spermine has been researched along with Invasiveness, Neoplasm in 6 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " Highly metastatic colon cancer cells (HT-29) were cultured under either normoxia (21% O2) or hypoxia (2% O2) for 48 h with 0, 100, or 500 µM spermine, one of the natural polyamines with the strongest biological activity." | 7.77 | Spermine accelerates hypoxia-initiated cancer cell migration. ( Kano, Y; Konishi, F; Soda, K; Tsujinaka, S, 2011) |
| "Our previous study showed that treatment of highly invasive rat ascites hepatoma (LC-AH) cells with alpha-difluoromethylornithine (DFMO), an inhibitor of ornithine decarboxylase, decreased both their intracellular level of putrescine and their in vitro invasion of a monolayer of calf pulmonary arterial endothelial (CPAE) cells, and that both these decreases were completely reversed by exogenous putrescine, but not spermidine or spermine." | 7.70 | Putrescine-stimulated intracellular Ca2+ release for invasiveness of rat ascites hepatoma cells. ( Ashida, Y; Inoue, H; Miwa, Y; Miyoshi, K; Ueno, A, 1998) |
| " Highly metastatic colon cancer cells (HT-29) were cultured under either normoxia (21% O2) or hypoxia (2% O2) for 48 h with 0, 100, or 500 µM spermine, one of the natural polyamines with the strongest biological activity." | 3.77 | Spermine accelerates hypoxia-initiated cancer cell migration. ( Kano, Y; Konishi, F; Soda, K; Tsujinaka, S, 2011) |
| "Our previous study showed that treatment of highly invasive rat ascites hepatoma (LC-AH) cells with alpha-difluoromethylornithine (DFMO), an inhibitor of ornithine decarboxylase, decreased both their intracellular level of putrescine and their in vitro invasion of a monolayer of calf pulmonary arterial endothelial (CPAE) cells, and that both these decreases were completely reversed by exogenous putrescine, but not spermidine or spermine." | 3.70 | Putrescine-stimulated intracellular Ca2+ release for invasiveness of rat ascites hepatoma cells. ( Ashida, Y; Inoue, H; Miwa, Y; Miyoshi, K; Ueno, A, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kielbik, M | 1 |
| Szulc, I | 1 |
| Brzezinska, M | 1 |
| Bednarska, K | 1 |
| Przygodzka, P | 1 |
| Sulowska, Z | 1 |
| Nowak, M | 1 |
| Klink, M | 1 |
| Takahashi, Y | 1 |
| Horio, H | 1 |
| Sakaguchi, K | 1 |
| Hiramatsu, K | 1 |
| Kawakita, M | 1 |
| Wang, Q | 1 |
| Li, H | 1 |
| Sun, Z | 1 |
| Dong, L | 1 |
| Gao, L | 1 |
| Liu, C | 1 |
| Wang, X | 1 |
| Tsujinaka, S | 1 |
| Soda, K | 1 |
| Kano, Y | 1 |
| Konishi, F | 1 |
| Smith, RC | 1 |
| Litwin, MS | 1 |
| Lu, Y | 1 |
| Zetter, BR | 1 |
| Ashida, Y | 1 |
| Ueno, A | 1 |
| Miwa, Y | 1 |
| Miyoshi, K | 1 |
| Inoue, H | 1 |
6 other studies available for spermine and Invasiveness, Neoplasm
| Article | Year |
|---|---|
Nitric oxide donors reduce the invasion ability of ovarian cancer cells in vitro.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Survival; Female; Humans; Matrix Metall | 2014 |
Significant correlation between urinary N(1), N(12)-diacetylspermine and tumor invasiveness in patients with clinical stage IA non-small cell lung cancer.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Creatinine; Femal | 2015 |
Kukoamine A inhibits human glioblastoma cell growth and migration through apoptosis induction and epithelial-mesenchymal transition attenuation.
Topics: Animals; Apoptosis; Cell Movement; Epithelial-Mesenchymal Transition; G1 Phase Cell Cycle Checkpoint | 2016 |
Spermine accelerates hypoxia-initiated cancer cell migration.
Topics: Blotting, Western; Cadherins; Cell Movement; Cell Proliferation; Collagen; Colonic Neoplasms; Dose-R | 2011 |
Identification of an endogenous inhibitor of prostatic carcinoma cell growth.
Topics: Adenocarcinoma; Animals; Enzyme Inhibitors; Growth Inhibitors; Guanidines; Humans; Male; Neoplasm In | 1995 |
Putrescine-stimulated intracellular Ca2+ release for invasiveness of rat ascites hepatoma cells.
Topics: Animals; Ascites; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Carcinoma, Hepatocell | 1998 |