spermine has been researched along with Insulin Resistance in 11 studies
Insulin Resistance: Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The importance of hypothalamic leptin and insulin resistance in the development and maintenance of obesity remains unclear." | 7.91 | Intranasal Targeting of Hypothalamic PTP1B and TCPTP Reinstates Leptin and Insulin Sensitivity and Promotes Weight Loss in Obesity. ( Andrews, ZB; Cowley, MA; Dodd, GT; Eramo, M; Henry, BA; Mitchell, CA; Tiganis, T; Xirouchaki, CE, 2019) |
| "Insulin resistance is believed to be the key mechanism mediating initial accumulation of fat in the liver, resulting in hepatic steatosis." | 5.46 | Kukoamine A attenuates insulin resistance and fatty liver through downregulation of Srebp-1c. ( Chen, Y; Li, G; Wang, N; Zhang, W; Zhou, F, 2017) |
| "The importance of hypothalamic leptin and insulin resistance in the development and maintenance of obesity remains unclear." | 3.91 | Intranasal Targeting of Hypothalamic PTP1B and TCPTP Reinstates Leptin and Insulin Sensitivity and Promotes Weight Loss in Obesity. ( Andrews, ZB; Cowley, MA; Dodd, GT; Eramo, M; Henry, BA; Mitchell, CA; Tiganis, T; Xirouchaki, CE, 2019) |
| "Insulin resistance is believed to be the key mechanism mediating initial accumulation of fat in the liver, resulting in hepatic steatosis." | 1.46 | Kukoamine A attenuates insulin resistance and fatty liver through downregulation of Srebp-1c. ( Chen, Y; Li, G; Wang, N; Zhang, W; Zhou, F, 2017) |
| "In obesity and type 2 diabetes, Glut4 glucose transporter expression is decreased selectively in adipocytes." | 1.40 | Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity. ( Alhonen, L; Asara, JM; Banks, AS; Bhanot, S; Cen, Y; Gong, F; Kahn, BB; Kong, D; Kraus, D; Monia, BP; Peroni, OD; Pirinen, E; Puigserver, P; Pulinilkunnil, TC; Rodgers, JT; Sauve, AA; Wang, YC; Yang, Q; Zhang, L, 2014) |
| " Furthermore, the quantitatively predicted rightward shift in the insulin-glucose transport dose-response curve could be demonstrated." | 1.26 | Effects of insulin incubation on insulin binding, glucose transport, and insulin degradation by isolated rat adipocytes. Evidence for hormone-induced desensitization at the receptor and postreceptor level. ( Marshall, S; Olefsky, JM, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (36.36) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (36.36) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Dodd, GT | 1 |
| Xirouchaki, CE | 1 |
| Eramo, M | 1 |
| Mitchell, CA | 1 |
| Andrews, ZB | 1 |
| Henry, BA | 1 |
| Cowley, MA | 1 |
| Tiganis, T | 1 |
| Ricke, KM | 1 |
| Cruz, SA | 1 |
| Qin, Z | 2 |
| Farrokhi, K | 1 |
| Sharmin, F | 1 |
| Zhang, L | 2 |
| Zasloff, MA | 1 |
| Stewart, AFR | 1 |
| Chen, HH | 2 |
| Pandey, NR | 1 |
| Zhou, X | 1 |
| Zaman, T | 1 |
| Gomez-Smith, M | 1 |
| Keyhanian, K | 1 |
| Anisman, H | 1 |
| Brunel, JM | 1 |
| Stewart, AF | 1 |
| Kraus, D | 1 |
| Yang, Q | 1 |
| Kong, D | 1 |
| Banks, AS | 1 |
| Rodgers, JT | 1 |
| Pirinen, E | 1 |
| Pulinilkunnil, TC | 1 |
| Gong, F | 1 |
| Wang, YC | 1 |
| Cen, Y | 1 |
| Sauve, AA | 1 |
| Asara, JM | 1 |
| Peroni, OD | 1 |
| Monia, BP | 1 |
| Bhanot, S | 1 |
| Alhonen, L | 1 |
| Puigserver, P | 1 |
| Kahn, BB | 1 |
| Li, G | 1 |
| Zhou, F | 1 |
| Chen, Y | 1 |
| Zhang, W | 1 |
| Wang, N | 1 |
| Marshall, S | 1 |
| Olefsky, JM | 2 |
| Galasko, GT | 1 |
| Abe, S | 1 |
| Lilley, K | 1 |
| Zhang, C | 1 |
| Larner, J | 1 |
| Ushmorov, A | 1 |
| Hack, V | 1 |
| Dröge, W | 1 |
| Lockwood, DH | 2 |
| Livingston, JN | 2 |
| Amatruda, JM | 1 |
| Cuatrecasa, P | 1 |
1 review available for spermine and Insulin Resistance
| Article | Year |
|---|---|
LIlly lecture 1980. Insulin resistance and insulin action. An in vitro and in vivo perspective.
Topics: Adipose Tissue; Adult; Animals; Blood Glucose; Child, Preschool; Deoxyglucose; Diabetes Mellitus; Do | 1981 |
10 other studies available for spermine and Insulin Resistance
| Article | Year |
|---|---|
Intranasal Targeting of Hypothalamic PTP1B and TCPTP Reinstates Leptin and Insulin Sensitivity and Promotes Weight Loss in Obesity.
Topics: Adipose Tissue, White; Administration, Intranasal; Animals; Blood-Brain Barrier; Cholestanes; Diet, | 2019 |
Neuronal Protein Tyrosine Phosphatase 1B Hastens Amyloid β-Associated Alzheimer's Disease in Mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cholestanes; Disease Models, Animal; Female; Glyc | 2020 |
The LIM domain only 4 protein is a metabolic responsive inhibitor of protein tyrosine phosphatase 1B that controls hypothalamic leptin signaling.
Topics: Adaptor Proteins, Signal Transducing; Adrenal Glands; Animals; Bacterial Proteins; Blood Pressure; B | 2013 |
Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity.
Topics: Acetyltransferases; Adipocytes; Adipose Tissue; Adipose Tissue, White; Animals; Diabetes Mellitus, T | 2014 |
Kukoamine A attenuates insulin resistance and fatty liver through downregulation of Srebp-1c.
Topics: Animals; Dietary Fats; Dose-Response Relationship, Drug; Gene Expression Regulation; Insulin Resista | 2017 |
Effects of insulin incubation on insulin binding, glucose transport, and insulin degradation by isolated rat adipocytes. Evidence for hormone-induced desensitization at the receptor and postreceptor level.
Topics: Adipose Tissue; Animals; Biological Transport; Glucose; In Vitro Techniques; Insulin; Insulin Antibo | 1980 |
Circulating factors and insulin resistance. II. The action of the novel myo-inositol cyclic 1,2-inositol phosphate phosphoglycan insulin antagonist from human plasma in regulating pyruvate dehydrogenase phosphatase.
Topics: Animals; Blood Physiological Phenomena; Cattle; Humans; Inositol Phosphates; Insulin Antagonists; In | 1996 |
Differential reconstitution of mitochondrial respiratory chain activity and plasma redox state by cysteine and ornithine in a model of cancer cachexia.
Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Biomarkers; Blood Glucose; Cachexia; Cysteine; Cyst | 1999 |
Relation of insulin receptors to insulin resistance.
Topics: Adipose Tissue; Animals; Biological Transport, Active; Glucose; Humans; Insulin; Insulin Resistance; | 1975 |
Insulin insensitivity of large fat cells.
Topics: Adipose Tissue; Animals; Glucose; In Vitro Techniques; Insulin; Insulin Resistance; Iodine Isotopes; | 1972 |