Page last updated: 2024-10-20

spermine and Insulin Resistance

spermine has been researched along with Insulin Resistance in 11 studies

Insulin Resistance: Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.

Research Excerpts

ExcerptRelevanceReference
"The importance of hypothalamic leptin and insulin resistance in the development and maintenance of obesity remains unclear."7.91Intranasal Targeting of Hypothalamic PTP1B and TCPTP Reinstates Leptin and Insulin Sensitivity and Promotes Weight Loss in Obesity. ( Andrews, ZB; Cowley, MA; Dodd, GT; Eramo, M; Henry, BA; Mitchell, CA; Tiganis, T; Xirouchaki, CE, 2019)
"Insulin resistance is believed to be the key mechanism mediating initial accumulation of fat in the liver, resulting in hepatic steatosis."5.46Kukoamine A attenuates insulin resistance and fatty liver through downregulation of Srebp-1c. ( Chen, Y; Li, G; Wang, N; Zhang, W; Zhou, F, 2017)
"The importance of hypothalamic leptin and insulin resistance in the development and maintenance of obesity remains unclear."3.91Intranasal Targeting of Hypothalamic PTP1B and TCPTP Reinstates Leptin and Insulin Sensitivity and Promotes Weight Loss in Obesity. ( Andrews, ZB; Cowley, MA; Dodd, GT; Eramo, M; Henry, BA; Mitchell, CA; Tiganis, T; Xirouchaki, CE, 2019)
"Insulin resistance is believed to be the key mechanism mediating initial accumulation of fat in the liver, resulting in hepatic steatosis."1.46Kukoamine A attenuates insulin resistance and fatty liver through downregulation of Srebp-1c. ( Chen, Y; Li, G; Wang, N; Zhang, W; Zhou, F, 2017)
"In obesity and type 2 diabetes, Glut4 glucose transporter expression is decreased selectively in adipocytes."1.40Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity. ( Alhonen, L; Asara, JM; Banks, AS; Bhanot, S; Cen, Y; Gong, F; Kahn, BB; Kong, D; Kraus, D; Monia, BP; Peroni, OD; Pirinen, E; Puigserver, P; Pulinilkunnil, TC; Rodgers, JT; Sauve, AA; Wang, YC; Yang, Q; Zhang, L, 2014)
" Furthermore, the quantitatively predicted rightward shift in the insulin-glucose transport dose-response curve could be demonstrated."1.26Effects of insulin incubation on insulin binding, glucose transport, and insulin degradation by isolated rat adipocytes. Evidence for hormone-induced desensitization at the receptor and postreceptor level. ( Marshall, S; Olefsky, JM, 1980)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19904 (36.36)18.7374
1990's2 (18.18)18.2507
2000's0 (0.00)29.6817
2010's4 (36.36)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Dodd, GT1
Xirouchaki, CE1
Eramo, M1
Mitchell, CA1
Andrews, ZB1
Henry, BA1
Cowley, MA1
Tiganis, T1
Ricke, KM1
Cruz, SA1
Qin, Z2
Farrokhi, K1
Sharmin, F1
Zhang, L2
Zasloff, MA1
Stewart, AFR1
Chen, HH2
Pandey, NR1
Zhou, X1
Zaman, T1
Gomez-Smith, M1
Keyhanian, K1
Anisman, H1
Brunel, JM1
Stewart, AF1
Kraus, D1
Yang, Q1
Kong, D1
Banks, AS1
Rodgers, JT1
Pirinen, E1
Pulinilkunnil, TC1
Gong, F1
Wang, YC1
Cen, Y1
Sauve, AA1
Asara, JM1
Peroni, OD1
Monia, BP1
Bhanot, S1
Alhonen, L1
Puigserver, P1
Kahn, BB1
Li, G1
Zhou, F1
Chen, Y1
Zhang, W1
Wang, N1
Marshall, S1
Olefsky, JM2
Galasko, GT1
Abe, S1
Lilley, K1
Zhang, C1
Larner, J1
Ushmorov, A1
Hack, V1
Dröge, W1
Lockwood, DH2
Livingston, JN2
Amatruda, JM1
Cuatrecasa, P1

Reviews

1 review available for spermine and Insulin Resistance

ArticleYear
LIlly lecture 1980. Insulin resistance and insulin action. An in vitro and in vivo perspective.
    Diabetes, 1981, Volume: 30, Issue:2

    Topics: Adipose Tissue; Adult; Animals; Blood Glucose; Child, Preschool; Deoxyglucose; Diabetes Mellitus; Do

1981

Other Studies

10 other studies available for spermine and Insulin Resistance

ArticleYear
Intranasal Targeting of Hypothalamic PTP1B and TCPTP Reinstates Leptin and Insulin Sensitivity and Promotes Weight Loss in Obesity.
    Cell reports, 2019, Sep-10, Volume: 28, Issue:11

    Topics: Adipose Tissue, White; Administration, Intranasal; Animals; Blood-Brain Barrier; Cholestanes; Diet,

2019
Neuronal Protein Tyrosine Phosphatase 1B Hastens Amyloid β-Associated Alzheimer's Disease in Mice.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2020, 02-12, Volume: 40, Issue:7

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cholestanes; Disease Models, Animal; Female; Glyc

2020
The LIM domain only 4 protein is a metabolic responsive inhibitor of protein tyrosine phosphatase 1B that controls hypothalamic leptin signaling.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, Jul-31, Volume: 33, Issue:31

    Topics: Adaptor Proteins, Signal Transducing; Adrenal Glands; Animals; Bacterial Proteins; Blood Pressure; B

2013
Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity.
    Nature, 2014, Apr-10, Volume: 508, Issue:7495

    Topics: Acetyltransferases; Adipocytes; Adipose Tissue; Adipose Tissue, White; Animals; Diabetes Mellitus, T

2014
Kukoamine A attenuates insulin resistance and fatty liver through downregulation of Srebp-1c.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 89

    Topics: Animals; Dietary Fats; Dose-Response Relationship, Drug; Gene Expression Regulation; Insulin Resista

2017
Effects of insulin incubation on insulin binding, glucose transport, and insulin degradation by isolated rat adipocytes. Evidence for hormone-induced desensitization at the receptor and postreceptor level.
    The Journal of clinical investigation, 1980, Volume: 66, Issue:4

    Topics: Adipose Tissue; Animals; Biological Transport; Glucose; In Vitro Techniques; Insulin; Insulin Antibo

1980
Circulating factors and insulin resistance. II. The action of the novel myo-inositol cyclic 1,2-inositol phosphate phosphoglycan insulin antagonist from human plasma in regulating pyruvate dehydrogenase phosphatase.
    The Journal of clinical endocrinology and metabolism, 1996, Volume: 81, Issue:3

    Topics: Animals; Blood Physiological Phenomena; Cattle; Humans; Inositol Phosphates; Insulin Antagonists; In

1996
Differential reconstitution of mitochondrial respiratory chain activity and plasma redox state by cysteine and ornithine in a model of cancer cachexia.
    Cancer research, 1999, Jul-15, Volume: 59, Issue:14

    Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Biomarkers; Blood Glucose; Cachexia; Cysteine; Cyst

1999
Relation of insulin receptors to insulin resistance.
    Federation proceedings, 1975, Volume: 34, Issue:7

    Topics: Adipose Tissue; Animals; Biological Transport, Active; Glucose; Humans; Insulin; Insulin Resistance;

1975
Insulin insensitivity of large fat cells.
    Science (New York, N.Y.), 1972, Aug-18, Volume: 177, Issue:4049

    Topics: Adipose Tissue; Animals; Glucose; In Vitro Techniques; Insulin; Insulin Resistance; Iodine Isotopes;

1972