spermine has been researched along with Infarction, Middle Cerebral Artery in 6 studies
Infarction, Middle Cerebral Artery: NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here, we show that extracellular spermine, one of the endogenous polyamines, exacerbates ischemic neuronal injury through sensitization of ASIC1a channels to extracellular acidosis." | 7.77 | Extracellular spermine exacerbates ischemic neuronal injury through sensitization of ASIC1a channels to extracellular acidosis. ( Cao, H; Chu, XP; Duan, B; Hansen, J; Huang, Y; Simon, RP; Wang, YZ; Xiong, ZG; Xu, TL; Yang, T; Yu, Y; Zhu, MX, 2011) |
| " Here, we show that extracellular spermine, one of the endogenous polyamines, exacerbates ischemic neuronal injury through sensitization of ASIC1a channels to extracellular acidosis." | 3.77 | Extracellular spermine exacerbates ischemic neuronal injury through sensitization of ASIC1a channels to extracellular acidosis. ( Cao, H; Chu, XP; Duan, B; Hansen, J; Huang, Y; Simon, RP; Wang, YZ; Xiong, ZG; Xu, TL; Yang, T; Yu, Y; Zhu, MX, 2011) |
| "Diazoxide and spermine were administrated 30 minutes before ischemia or 10 minutes before reperfusion, respectively." | 1.40 | Spermine attenuates the preconditioning of diazoxide against transient focal cerebral ischemia in rats. ( Dong, H; Guo, Y; Li, S; Li, Y; Wang, P; Wang, S; Yao, R; Zhang, L, 2014) |
| "The intraluminal suture transient middle cerebral artery occlusion (MCAO) model was used." | 1.33 | The pre-ischaemic neuroprotective effects of N1-dansyl-spermine in a transient focal cerebral ischaemia model in mice. ( Doyle, KM; Henman, MC; Li, J; Shaw, GG; Tatlisumak, T, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liang, N | 1 |
| Wang, P | 2 |
| Wang, S | 2 |
| Li, S | 2 |
| Li, Y | 2 |
| Wang, J | 1 |
| Wang, M | 1 |
| Zhang, L | 1 |
| Dong, H | 1 |
| Guo, Y | 1 |
| Yao, R | 1 |
| Saiki, R | 1 |
| Nishimura, K | 1 |
| Ishii, I | 1 |
| Omura, T | 1 |
| Okuyama, S | 1 |
| Kashiwagi, K | 1 |
| Igarashi, K | 1 |
| Duan, B | 1 |
| Wang, YZ | 1 |
| Yang, T | 1 |
| Chu, XP | 1 |
| Yu, Y | 1 |
| Huang, Y | 1 |
| Cao, H | 1 |
| Hansen, J | 1 |
| Simon, RP | 1 |
| Zhu, MX | 1 |
| Xiong, ZG | 1 |
| Xu, TL | 1 |
| Shirhan, MD | 1 |
| Moochhala, SM | 1 |
| Ng, PY | 1 |
| Lu, J | 1 |
| Ng, KC | 1 |
| Teo, AL | 1 |
| Yap, E | 1 |
| Ng, I | 1 |
| Hwang, P | 1 |
| Lim, T | 1 |
| Sitoh, YY | 1 |
| Rumpel, H | 1 |
| Jose, R | 1 |
| Ling, E | 1 |
| Li, J | 1 |
| Henman, MC | 1 |
| Tatlisumak, T | 1 |
| Shaw, GG | 1 |
| Doyle, KM | 1 |
6 other studies available for spermine and Infarction, Middle Cerebral Artery
| Article | Year |
|---|---|
Role of mitochondrial calcium uniporter in regulating mitochondrial fission in the cerebral cortexes of living rats.
Topics: Animals; Calcineurin; Calcium; Calcium Channels; Cerebral Cortex; Disease Models, Animal; Dynamins; | 2014 |
Spermine attenuates the preconditioning of diazoxide against transient focal cerebral ischemia in rats.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Brain; Calcium Channels; Cytochromes c; Diazoxide; I | 2014 |
Intense correlation between brain infarction and protein-conjugated acrolein.
Topics: Acetylcysteine; Acrolein; Animals; Brain; Carrier Proteins; Disease Models, Animal; Down-Regulation; | 2009 |
Extracellular spermine exacerbates ischemic neuronal injury through sensitization of ASIC1a channels to extracellular acidosis.
Topics: Acid Sensing Ion Channels; Acidosis; Amino Acid Transport System y+; Animals; Biophysics; Brain Inju | 2011 |
Spermine reduces infarction and neurological deficit following a rat model of middle cerebral artery occlusion: a magnetic resonance imaging study.
Topics: Analysis of Variance; Animals; Behavior, Animal; Brain Chemistry; Brain Infarction; Brain Mapping; D | 2004 |
The pre-ischaemic neuroprotective effects of N1-dansyl-spermine in a transient focal cerebral ischaemia model in mice.
Topics: Animals; Brain; Brain Edema; Dansyl Compounds; Disease Models, Animal; Dizocilpine Maleate; Dose-Res | 2005 |