spermine has been researched along with Disease Exacerbation in 7 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " Polyamine analogs down-regulate ornithine decarboxylase, induce spermidine/spermine N1-acetyltransferase, deplete natural polyamine pools, inhibit growth, and induce programmed cell death in breast cancer models." | 9.10 | A Phase II study of the polyamine analog N1,N11-diethylnorspermine (DENSpm) daily for five days every 21 days in patients with previously treated metastatic breast cancer. ( Armstrong, DK; Bender, JF; Carducci, MK; Casero, RA; Davidson, NE; Fetting, JH; Riley, CD; Wolff, AC, 2003) |
| " Polyamine analogs down-regulate ornithine decarboxylase, induce spermidine/spermine N1-acetyltransferase, deplete natural polyamine pools, inhibit growth, and induce programmed cell death in breast cancer models." | 5.10 | A Phase II study of the polyamine analog N1,N11-diethylnorspermine (DENSpm) daily for five days every 21 days in patients with previously treated metastatic breast cancer. ( Armstrong, DK; Bender, JF; Carducci, MK; Casero, RA; Davidson, NE; Fetting, JH; Riley, CD; Wolff, AC, 2003) |
| " Moreover, pTAb progression to overt hypothyroidism may be related to high N-acetylspermidine." | 3.91 | Serum polyamine metabolic profile in autoimmune thyroid disease patients. ( Mao, J; Shan, Z; Song, J; Teng, W, 2019) |
| "Separating indolent from aggressive prostate cancer is an important clinical challenge for identifying patients eligible for active surveillance, thereby reducing the risk of overtreatment." | 1.39 | Spermine and citrate as metabolic biomarkers for assessing prostate cancer aggressiveness. ( Angelsen, A; Bathen, TF; Bertilsson, H; Giskeødegård, GF; Gribbestad, IS; Halgunset, J; Selnæs, KM; Tessem, MB; Viset, T; Wright, AJ, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xie, L | 1 |
| Yang, Y | 1 |
| Meng, J | 1 |
| Wen, T | 1 |
| Liu, J | 1 |
| Xu, H | 1 |
| Song, J | 1 |
| Shan, Z | 1 |
| Mao, J | 1 |
| Teng, W | 1 |
| Giskeødegård, GF | 1 |
| Bertilsson, H | 1 |
| Selnæs, KM | 1 |
| Wright, AJ | 1 |
| Bathen, TF | 1 |
| Viset, T | 1 |
| Halgunset, J | 1 |
| Angelsen, A | 1 |
| Gribbestad, IS | 1 |
| Tessem, MB | 1 |
| Hong, SH | 1 |
| Kim, JE | 1 |
| Kim, YK | 1 |
| Minai-Tehrani, A | 1 |
| Shin, JY | 1 |
| Kang, B | 1 |
| Kim, HJ | 1 |
| Cho, CS | 1 |
| Chae, C | 1 |
| Jiang, HL | 1 |
| Cho, MH | 1 |
| Wolff, AC | 1 |
| Armstrong, DK | 1 |
| Fetting, JH | 1 |
| Carducci, MK | 1 |
| Riley, CD | 1 |
| Bender, JF | 1 |
| Casero, RA | 1 |
| Davidson, NE | 1 |
| Rioux-Leclercq, N | 1 |
| Delcros, JG | 1 |
| Bansard, JY | 1 |
| Epstein, JI | 1 |
| Patard, JJ | 1 |
| Lobel, B | 1 |
| Guillé, F | 1 |
| Jouan, F | 1 |
| Bellaud, P | 1 |
| Moulinoux, JP | 1 |
| Schleiffer, R | 1 |
| Duranton, B | 1 |
| Gossé, F | 1 |
| Hasselmann, M | 1 |
| Raul, F | 1 |
1 trial available for spermine and Disease Exacerbation
| Article | Year |
|---|---|
A Phase II study of the polyamine analog N1,N11-diethylnorspermine (DENSpm) daily for five days every 21 days in patients with previously treated metastatic breast cancer.
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Disease Progression; Drug Administration Sched | 2003 |
6 other studies available for spermine and Disease Exacerbation
| Article | Year |
|---|---|
Cationic polysaccharide spermine-pullulan drives tumor associated macrophage towards M1 phenotype to inhibit tumor progression.
Topics: Animals; Cations; Cell Line, Tumor; Cell Polarity; Disease Progression; Female; Glucans; Lectins, C- | 2019 |
Serum polyamine metabolic profile in autoimmune thyroid disease patients.
Topics: Adult; Autoantibodies; Disease Progression; Female; Graves Disease; Hashimoto Disease; Humans; Hypot | 2019 |
Spermine and citrate as metabolic biomarkers for assessing prostate cancer aggressiveness.
Topics: Aged; Biomarkers, Tumor; Citric Acid; Disease Progression; Electron Spin Resonance Spectroscopy; Hum | 2013 |
Suppression of lung cancer progression by biocompatible glycerol triacrylate-spermine-mediated delivery of shAkt1.
Topics: Aerosols; Animals; Cell Line, Tumor; Disease Progression; Drug Carriers; Female; Genetic Therapy; Gl | 2012 |
Immunohistochemical analysis of tumor polyamines discriminates high-risk patients undergoing nephrectomy for renal cell carcinoma.
Topics: Adult; Aged; Antibodies, Monoclonal; Biomarkers, Tumor; Carcinoma, Renal Cell; Disease Progression; | 2004 |
Blood polyamine levels after oral ornithine load, a diagnostic marker of hyperproliferative premalignant and malignant stages in a model of colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Biomarkers, Tumor; Biotransformation; Body | 2000 |