Page last updated: 2024-10-20

spermine and Diabetes Mellitus

spermine has been researched along with Diabetes Mellitus in 4 studies

Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.

Research Excerpts

ExcerptRelevanceReference
"We describe the pharmacological properties of a novel spermine-cholesterol adduct, MSI 1436 (3beta-N-1(spermine)-7alpha, 24R-dihydroxy-5alpha-cholestane 24-sulfate), which causes reversible suppression of food and fluid intake in mammals resulting in profound weight loss, not associated with other signs or symptoms of illness, and which exhibits antidiabetic properties in genetically obese mice."3.71A spermine-coupled cholesterol metabolite from the shark with potent appetite suppressant and antidiabetic properties. ( Anderson, M; Chen, Q; Cheshire, K; Holroyd, K; Jones, S; Kinney, W; Maeder, T; McLane, M; Williams, JI; Zasloff, M, 2001)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's2 (50.00)2.80

Authors

AuthorsStudies
Wei, C2
Song, T1
Yuan, H1
Li, X1
Zhang, X2
Liang, X1
Fan, Y1
Wang, Y1
Chen, J1
Li, S1
Guo, Z1
Hu, J1
Shao, X1
Song, N1
Zhao, Y1
Li, H1
Yang, G1
Xu, C1
Olefsky, JM1
Zasloff, M1
Williams, JI1
Chen, Q1
Anderson, M1
Maeder, T1
Holroyd, K1
Jones, S1
Kinney, W1
Cheshire, K1
McLane, M1

Reviews

1 review available for spermine and Diabetes Mellitus

ArticleYear
LIlly lecture 1980. Insulin resistance and insulin action. An in vitro and in vivo perspective.
    Diabetes, 1981, Volume: 30, Issue:2

    Topics: Adipose Tissue; Adult; Animals; Blood Glucose; Child, Preschool; Deoxyglucose; Diabetes Mellitus; Do

1981

Other Studies

3 other studies available for spermine and Diabetes Mellitus

ArticleYear
Transcriptomics Coupled to Proteomics Reveals Novel Targets for the Protective Role of Spermine in Diabetic Cardiomyopathy.
    Oxidative medicine and cellular longevity, 2022, Volume: 2022

    Topics: Amino Acids; Animals; Computational Biology; Diabetes Mellitus; Diabetic Cardiomyopathies; Disease M

2022
Exogenous spermine attenuates rat diabetic cardiomyopathy via suppressing ROS-p53 mediated downregulation of calcium-sensitive receptor.
    Redox biology, 2020, Volume: 32

    Topics: Animals; Apoptosis; Calcium; Diabetes Mellitus; Diabetic Cardiomyopathies; Down-Regulation; Rats; Re

2020
A spermine-coupled cholesterol metabolite from the shark with potent appetite suppressant and antidiabetic properties.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 2001, Volume: 25, Issue:5

    Topics: Animals; Appetite Depressants; Cholestanes; Diabetes Mellitus; Disease Models, Animal; Dogfish; Drin

2001