spermine has been researched along with Cystic Fibrosis in 14 studies
Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Previous studies have shown an abnormality of the spermidine-to-spermine (Spd/Spm) ratio in whole blood of cystic fibrosis homo-and heterozygotes." | 7.65 | Distribution of spermidine and spermine in blood from cystic fibrosis patients and control subjects. ( Cohen, LF; Farrell, PM; Lundgren, DW, 1976) |
| "Serum putrescine (Pu), spermidine (Sd), spermine (Sp), and plasma diamine oxidase ativity (DAO) were determined in cystic fibrosis (CF) homozygotes and heterozygotes plus age-matched controls." | 3.66 | Age-related abnormalities of circulating polyamines and diamine oxidase activity in cystic fibrosis heterozygotes and homozygotes. ( Baylin, SB; Lockwood, DH; Marton, LJ; Rosenstein, BJ, 1980) |
| "Children with cystic fibrosis excreted elevated urinary levels of all three polyamines--putrescine, spermidine, and spermine." | 3.66 | Altered polyamine metabolism in cystic fibrosis. ( Barnett, DR; Beckerman, RC; Durie, BG; Rosenblum, MG; Russell, DH; Taussig, LM, 1979) |
| "Previous studies have shown an abnormality of the spermidine-to-spermine (Spd/Spm) ratio in whole blood of cystic fibrosis homo-and heterozygotes." | 3.65 | Distribution of spermidine and spermine in blood from cystic fibrosis patients and control subjects. ( Cohen, LF; Farrell, PM; Lundgren, DW, 1976) |
| "The polyamines, spermidine and spermine, have been measured in whole blood extracts from control volunteers, patients with cystic fibrosis, and obligate cystic fibrosis heterozygotes." | 3.65 | Polyamine alterations in blood of male homozygotes and heterozygotes for cystic fibrosis. ( Di Sant'Agnese, PA; Farrell, PM; Lundgren, DW, 1975) |
| " Formulation with 3beta [N-(N', N'-dimethylaminoethane) carbamoy] cholesterol (DC-Chol) DC-cholesterol (DC-Chol))/DOPE or dexamethasone in the first dosing at day 0 resulted in moderate alkaline phosphatase expression at day 24." | 1.34 | Pulmonary delivery of adenovirus vector formulated with dexamethasone-spermine facilitates homologous vector re-administration. ( Diamond, SL; Limberis, MP; Price, AR; Wilson, JM, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (64.29) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dubarry, N | 1 |
| Du, W | 1 |
| Lane, D | 1 |
| Pasta, F | 1 |
| Fein, DE | 1 |
| Bucki, R | 1 |
| Byfield, F | 1 |
| Leszczynska, K | 1 |
| Janmey, PA | 1 |
| Diamond, SL | 2 |
| Price, AR | 1 |
| Limberis, MP | 1 |
| Wilson, JM | 1 |
| Theoharides, TC | 1 |
| Russell, DH | 2 |
| Baylin, SB | 1 |
| Rosenstein, BJ | 1 |
| Marton, LJ | 1 |
| Lockwood, DH | 1 |
| Fortunati, E | 1 |
| Bout, A | 1 |
| Zanta, MA | 1 |
| Valerio, D | 1 |
| Scarpa, M | 1 |
| Rückes-Nilges, C | 1 |
| Lindemann, H | 1 |
| Klimek, T | 1 |
| Glanz, H | 1 |
| Weber, WM | 1 |
| Rosenblum, MG | 1 |
| Beckerman, RC | 1 |
| Durie, BG | 1 |
| Taussig, LM | 1 |
| Barnett, DR | 1 |
| Wright, RK | 1 |
| Buehler, BA | 1 |
| Schott, SN | 1 |
| Rennert, OM | 1 |
| Gahl, WA | 1 |
| Changus, JE | 1 |
| Pitot, HC | 1 |
| Cohen, LF | 1 |
| Lundgren, DW | 2 |
| Farrell, PM | 2 |
| Di Sant'Agnese, PA | 1 |
| McEvoy, FA | 1 |
| Hartley, CB | 1 |
2 reviews available for spermine and Cystic Fibrosis
| Article | Year |
|---|---|
Polyamines spermidine and spermine as modulators of calcium-dependent immune processes.
Topics: Adenosine Diphosphate; Animals; Biological Transport; Calcium; Cystic Fibrosis; Enzyme Induction; ga | 1980 |
Clinical relevance of polyamines.
Topics: Animals; Cadaverine; Cystic Fibrosis; Diamines; Female; Growth Disorders; Humans; Kidney Failure, Ch | 1983 |
12 other studies available for spermine and Cystic Fibrosis
| Article | Year |
|---|---|
Improved electrotransformation and decreased antibiotic resistance of the cystic fibrosis pathogen Burkholderia cenocepacia strain J2315.
Topics: Base Sequence; Burkholderia cepacia complex; Culture Media; Cystic Fibrosis; DNA Methylation; DNA Pr | 2010 |
Novel cationic lipids with enhanced gene delivery and antimicrobial activity.
Topics: Animals; Anti-Infective Agents; Cations; Cattle; Cystic Fibrosis; Dexamethasone; DNA; Eukaryota; Gen | 2010 |
Pulmonary delivery of adenovirus vector formulated with dexamethasone-spermine facilitates homologous vector re-administration.
Topics: Adenoviridae; Alkaline Phosphatase; Animals; Antibodies; Cholesterol; Cystic Fibrosis; Dexamethasone | 2007 |
Age-related abnormalities of circulating polyamines and diamine oxidase activity in cystic fibrosis heterozygotes and homozygotes.
Topics: Adolescent; Adult; Age Factors; Amine Oxidase (Copper-Containing); Child; Child, Preschool; Cystic F | 1980 |
In vitro and in vivo gene transfer to pulmonary cells mediated by cationic liposomes.
Topics: 3T3 Cells; Adenoviridae; Animals; beta-Galactosidase; Bronchi; Cations; Cell Line; Cells, Cultured; | 1996 |
Nitric oxide has no beneficial effects on ion transport defects in cystic fibrosis human nasal epithelium.
Topics: Absorption; Calcium; Cells, Cultured; Chloride Channels; Chlorides; Cystic Fibrosis; Cystic Fibrosis | 2000 |
Altered polyamine metabolism in cystic fibrosis.
Topics: Adult; Child; Child, Preschool; Cystic Fibrosis; Female; Heterozygote; Humans; Male; Polyamines; Put | 1979 |
Spermine and spermidine, modulators of the cell surface enzyme adenylate cyclase.
Topics: Adenylyl Cyclase Inhibitors; Adult; Cell Membrane; Cells, Cultured; Child; Child, Preschool; Cystic | 1978 |
The effect of spermidine and spermine on proliferation in vitro of fibroblasts from normal and cystic fibrosis patients.
Topics: Cell Division; Cystic Fibrosis; Depression, Chemical; Fibroblasts; Humans; Spermidine; Spermine | 1976 |
Distribution of spermidine and spermine in blood from cystic fibrosis patients and control subjects.
Topics: Cell Fractionation; Cell Separation; Citrates; Cystic Fibrosis; Heparin; Humans; Male; Polyamines; S | 1976 |
Polyamine alterations in blood of male homozygotes and heterozygotes for cystic fibrosis.
Topics: Cystic Fibrosis; Female; Heterozygote; Homozygote; Humans; Male; Sex Factors; Spermidine; Spermine | 1975 |
Polyamines in cystic fibrosis.
Topics: Bile; Cystic Fibrosis; Duodenum; Humans; Intestinal Secretions; Polyamines; Saliva; Spermidine; Sper | 1975 |