spermine has been researched along with Cerebral Ischemia in 14 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " The effects of addition of putrescine on IR will be evaluated in terms of inflammation and oxidant-antioxidant balance in liver." | 8.31 | Effects of putrescine on oxidative stress, spermidine/spermine-N(1)-acetyltransferase, inflammation and energy levels in liver and serum in rats with brain ischemia-reperfusion. ( Baltaci, AK; Cetin, N; Dasdelen, D; Menevse, E; Mogulkoc, R, 2023) |
| "The aim of this study is to investigate the effects of spermine and the passive avoidance learning on hippocampus following transient cerebral ischemia in the chicks." | 7.88 | Effects of spermine and the passive avoidance learning (PAL) following cerebral ischemia in chicks: Association with neuroprotection of pyramidal cells. ( Altunkaynak, BZ; Deniz, OG; Elibol, E; Kaplan, S; Karayiğit, MÖ; Marangoz, C; Onger, ME; Ragbetli, MÇ; Yarım, M, 2018) |
| " Addition of carnosine to the treatment protocol for chronic brain ischemia normalized the content of putrescine and spermine." | 5.16 | Effects of carnosine on polyamine levels in red blood cells of patients with hypertonic discirculatory encephalopathy. ( Boldyrev, AA; Fedorova, TN; Makletsova, MG; Maksimova, MY, 2012) |
| " The effects of addition of putrescine on IR will be evaluated in terms of inflammation and oxidant-antioxidant balance in liver." | 4.31 | Effects of putrescine on oxidative stress, spermidine/spermine-N(1)-acetyltransferase, inflammation and energy levels in liver and serum in rats with brain ischemia-reperfusion. ( Baltaci, AK; Cetin, N; Dasdelen, D; Menevse, E; Mogulkoc, R, 2023) |
| "The aim of this study is to investigate the effects of spermine and the passive avoidance learning on hippocampus following transient cerebral ischemia in the chicks." | 3.88 | Effects of spermine and the passive avoidance learning (PAL) following cerebral ischemia in chicks: Association with neuroprotection of pyramidal cells. ( Altunkaynak, BZ; Deniz, OG; Elibol, E; Kaplan, S; Karayiğit, MÖ; Marangoz, C; Onger, ME; Ragbetli, MÇ; Yarım, M, 2018) |
| "Putrescine, spermidine, and spermine levels were measured in the cortex, caudoputamen, and hippocampus of rats during 30 min of severe forebrain ischemia (induced by occlusion of both carotid and vertebral arteries) and subsequent recirculation." | 3.67 | Polyamine changes in reversible cerebral ischemia. ( Djuricic, B; Hossmann, KA; Linn, F; Meese, C; Paschen, W; Schmidt-Kastner, R, 1987) |
| " These data indicate that the polyamine spermine is toxic to neurons in vitro and that toxicity is prevented by the NMDA-associated channel antagonist dizocilpine." | 1.29 | Polyamine neurotoxicity is antagonized by dizocilpine in cultured chick cortical neurons. ( Fahey, JM; Miller, LG; Pritchard, GA, 1993) |
| "Putrescine efflux was significantly increased in 2/5 animals with MCA occlusion but the increase in release was similar to the spontaneous fluctuations observed in control animals." | 1.29 | Release of spermidine from the rat cortex following permanent middle cerebral artery occlusion. ( Carboni, S; Carter, C; Fage, D; Poignet, H; Scatton, B; Voltz, C, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.14) | 18.7374 |
| 1990's | 4 (28.57) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Dasdelen, D | 1 |
| Cetin, N | 1 |
| Menevse, E | 1 |
| Baltaci, AK | 1 |
| Mogulkoc, R | 1 |
| Kaplan, S | 1 |
| Onger, ME | 1 |
| Altunkaynak, BZ | 1 |
| Elibol, E | 1 |
| Deniz, OG | 1 |
| Karayiğit, MÖ | 1 |
| Yarım, M | 1 |
| Marangoz, C | 1 |
| Ragbetli, MÇ | 1 |
| Liu, J | 1 |
| Jiang, X | 1 |
| Zhang, Q | 2 |
| Lin, S | 1 |
| Zhu, J | 1 |
| Zhang, Y | 1 |
| Du, J | 1 |
| Hu, X | 1 |
| Meng, W | 1 |
| Zhao, Q | 1 |
| Masuko, T | 1 |
| Suzuki, T | 1 |
| Miyake, M | 1 |
| Kusama-Eguchi, K | 1 |
| Kizawa, Y | 1 |
| Tomono, K | 1 |
| Kashiwagi, K | 1 |
| Igarashi, K | 1 |
| Kusama, T | 1 |
| Makletsova, MG | 1 |
| Fedorova, TN | 1 |
| Maksimova, MY | 1 |
| Boldyrev, AA | 1 |
| Zhang, G | 1 |
| Meng, F | 1 |
| Tian, H | 1 |
| Kirby, BP | 2 |
| Shaw, GG | 2 |
| Li, J | 1 |
| Henman, MC | 1 |
| Doyle, KM | 1 |
| Strbian, D | 1 |
| Tatlisumak, T | 1 |
| Noh, KM | 1 |
| Yokota, H | 1 |
| Mashiko, T | 1 |
| Castillo, PE | 1 |
| Zukin, RS | 1 |
| Bennett, MV | 1 |
| Fahey, JM | 1 |
| Pritchard, GA | 1 |
| Miller, LG | 1 |
| Carter, C | 1 |
| Poignet, H | 1 |
| Carboni, S | 1 |
| Fage, D | 1 |
| Voltz, C | 1 |
| Scatton, B | 1 |
| Ivanova, S | 1 |
| Botchkina, GI | 1 |
| Al-Abed, Y | 1 |
| Meistrell, M | 1 |
| Batliwalla, F | 1 |
| Dubinsky, JM | 1 |
| Iadecola, C | 1 |
| Wang, H | 1 |
| Gregersen, PK | 1 |
| Eaton, JW | 1 |
| Tracey, KJ | 1 |
| Sauer, D | 1 |
| Martin, P | 1 |
| Allegrini, PR | 1 |
| Bernasconi, R | 1 |
| Amacker, H | 1 |
| Fagg, GE | 1 |
| Paschen, W | 1 |
| Schmidt-Kastner, R | 1 |
| Djuricic, B | 1 |
| Meese, C | 1 |
| Linn, F | 1 |
| Hossmann, KA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase II Study of the Effects of Tiopronin on 3-Aminopropanal Level & Neurologic Outcome After Aneurysmal Subarachnoid Hemorrhage[NCT01095731] | Phase 2 | 60 participants (Actual) | Interventional | 2010-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for spermine and Cerebral Ischemia
| Article | Year |
|---|---|
Effects of carnosine on polyamine levels in red blood cells of patients with hypertonic discirculatory encephalopathy.
Topics: Adult; Aged; Brain Ischemia; Carnosine; Cerebrovascular Disorders; Erythrocytes; Female; Humans; Mal | 2012 |
13 other studies available for spermine and Cerebral Ischemia
| Article | Year |
|---|---|
Effects of putrescine on oxidative stress, spermidine/spermine-N(1)-acetyltransferase, inflammation and energy levels in liver and serum in rats with brain ischemia-reperfusion.
Topics: Acetyltransferases; Animals; Brain Ischemia; Inflammation; Liver; Male; Oxidative Stress; Putrescine | 2023 |
Effects of spermine and the passive avoidance learning (PAL) following cerebral ischemia in chicks: Association with neuroprotection of pyramidal cells.
Topics: Animals; Avoidance Learning; Brain; Brain Ischemia; Chickens; Neuroprotective Agents; Pyramidal Cell | 2018 |
Neuroprotective effects of Kukoamine A against cerebral ischemia via antioxidant and inactivation of apoptosis pathway.
Topics: Administration, Intravenous; Animals; Antioxidants; Apoptosis; Brain Ischemia; Dose-Response Relatio | 2017 |
Antagonism of NMDA receptors by butanesulfonyl-homospermine guanidine and neuroprotective effects in in vitro and in vivo.
Topics: Animals; Brain Ischemia; Cell Line, Tumor; Cell Survival; Excitatory Amino Acid Antagonists; Female; | 2012 |
Biphasic activation of apoptosis signal-regulating kinase 1-stress-activated protein kinase 1-c-Jun N-terminal protein kinase pathway is selectively mediated by Ca2+-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors involving oxidat
Topics: Acetylcysteine; Animals; Antioxidants; Brain Ischemia; Calcium; Calcium Channel Blockers; Calcium Ch | 2003 |
The neuroprotective effects of N1-dansyl-spermine in the gerbil model of cerebral ischaemia.
Topics: Analysis of Variance; Animals; Behavior, Animal; Body Temperature; Brain Ischemia; Cell Count; Dansy | 2004 |
The pre-ischaemic neuroprotective effect of a novel polyamine antagonist, N1-dansyl-spermine in a permanent focal cerebral ischaemia model in mice.
Topics: Analysis of Variance; Animals; Behavior, Animal; Brain Damage, Chronic; Brain Ischemia; Dansyl Compo | 2004 |
Blockade of calcium-permeable AMPA receptors protects hippocampal neurons against global ischemia-induced death.
Topics: Animals; Brain Ischemia; Calcium; Cell Death; Electrophysiology; Hippocampus; Histological Technique | 2005 |
Polyamine neurotoxicity is antagonized by dizocilpine in cultured chick cortical neurons.
Topics: Animals; Brain Ischemia; Cell Survival; Cells, Cultured; Cerebral Cortex; Chick Embryo; Dizocilpine | 1993 |
Release of spermidine from the rat cortex following permanent middle cerebral artery occlusion.
Topics: Animals; Brain Ischemia; Cerebral Arteries; Cerebral Cortex; Chromatography, High Pressure Liquid; E | 1995 |
Cerebral ischemia enhances polyamine oxidation: identification of enzymatically formed 3-aminopropanal as an endogenous mediator of neuronal and glial cell death.
Topics: Aldehydes; Animals; Brain Ischemia; Cell Death; Cell Line; Magnetic Resonance Spectroscopy; Neurogli | 1998 |
Differing effects of alpha-difluoromethylornithine and CGP 40116 on polyamine levels and infarct volume in a rat model of focal cerebral ischaemia.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Brain Ischemia; Cerebral Infarction; Eflornithine; Magn | 1992 |
Polyamine changes in reversible cerebral ischemia.
Topics: Animals; Brain Ischemia; Cerebral Cortex; Hippocampus; Polyamines; Putamen; Putrescine; Rats; Spermi | 1987 |