spermine has been researched along with Cell Transformation, Neoplastic in 27 studies
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chemoprevention is the long-term use of different chemical agents, both synthetic and natural, to prevent or delay the onset of disease." | 2.50 | Pharmacological and dietary agents for colorectal cancer chemoprevention: effects on polyamine metabolism (review). ( Linsalata, M; Orlando, A; Russo, F, 2014) |
| "Putrescine transport was inhibited to varying degrees by other polyamines, but not by amino acids or divalent cations." | 1.26 | Putrescine transport is greatly increased in human fibroblasts initiated to proliferate. ( Pohjanpelto, P, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (55.56) | 18.7374 |
| 1990's | 7 (25.93) | 18.2507 |
| 2000's | 2 (7.41) | 29.6817 |
| 2010's | 2 (7.41) | 24.3611 |
| 2020's | 1 (3.70) | 2.80 |
| Authors | Studies |
|---|---|
| Sierra, JC | 1 |
| Piazuelo, MB | 1 |
| Luis, PB | 1 |
| Barry, DP | 1 |
| Allaman, MM | 1 |
| Asim, M | 1 |
| Sebrell, TA | 1 |
| Finley, JL | 1 |
| Rose, KL | 1 |
| Hill, S | 1 |
| Holshouser, SL | 1 |
| Casero, RA | 1 |
| Cleveland, JL | 2 |
| Woster, PM | 1 |
| Schey, KL | 1 |
| Bimczok, D | 1 |
| Schneider, C | 1 |
| Gobert, AP | 1 |
| Wilson, KT | 1 |
| Linsalata, M | 1 |
| Orlando, A | 1 |
| Russo, F | 1 |
| Tang, B | 1 |
| Chow, JY | 1 |
| Dong, TX | 1 |
| Yang, SM | 1 |
| Lu, DS | 1 |
| Carethers, JM | 1 |
| Dong, H | 1 |
| Shao, C | 1 |
| Aoki, M | 1 |
| Furusawa, Y | 1 |
| Sugiura, M | 1 |
| Shafman, T | 1 |
| Mitchell, T | 1 |
| Griffin, J | 1 |
| Kufe, D | 1 |
| Heby, O | 1 |
| Oredsson, SM | 1 |
| Kanje, M | 1 |
| Sunkara, PS | 2 |
| Fowler, SK | 1 |
| Nishioka, K | 2 |
| O'Brien, TG | 3 |
| Saladik, D | 1 |
| Diamond, L | 2 |
| Cipolla, B | 1 |
| Guillé, F | 1 |
| Moulinoux, JP | 1 |
| Quemener, V | 1 |
| Staerman, F | 1 |
| Corbel, L | 1 |
| Lobel, B | 1 |
| Shantz, LM | 1 |
| Hu, RH | 1 |
| Pegg, AE | 1 |
| Peralta Soler, A | 1 |
| Gilliard, G | 1 |
| Megosh, L | 1 |
| George, K | 1 |
| Dai, H | 1 |
| Kramer, DL | 1 |
| Yang, C | 1 |
| Murti, KG | 1 |
| Porter, CW | 2 |
| Heigold, S | 1 |
| Sers, C | 1 |
| Bechtel, W | 1 |
| Ivanovas, B | 1 |
| Schäfer, R | 1 |
| Bauer, G | 1 |
| Don, S | 4 |
| Wiener, H | 3 |
| Bachrach, U | 4 |
| Pohjanpelto, P | 1 |
| Pargac, MB | 1 |
| Rao, PN | 1 |
| Fletcher, S | 1 |
| Neill, WA | 1 |
| Norval, M | 1 |
| Sen, U | 1 |
| Guha, S | 1 |
| Glikman, PL | 1 |
| Manni, A | 1 |
| Bartholomew, M | 1 |
| Demers, L | 1 |
| Quash, G | 1 |
| Ripoll, H | 1 |
| Gazzolo, L | 1 |
| Doutheau, A | 1 |
| Saba, A | 1 |
| Gore, J | 1 |
| Chang, BK | 1 |
| Libby, PR | 1 |
| Bergeron, RJ | 1 |
| Lembach, KJ | 1 |
| Glick, JL | 1 |
| Majumdar, A | 1 |
1 review available for spermine and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Pharmacological and dietary agents for colorectal cancer chemoprevention: effects on polyamine metabolism (review).
Topics: Anticarcinogenic Agents; Cell Transformation, Neoplastic; Chemoprevention; Colorectal Neoplasms; Hum | 2014 |
26 other studies available for spermine and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Spermine oxidase mediates Helicobacter pylori-induced gastric inflammation, DNA damage, and carcinogenic signaling.
Topics: Adenocarcinoma; Animals; beta Catenin; Cell Transformation, Neoplastic; DNA Damage; Gastritis; Helic | 2020 |
Calcium sensing receptor suppresses human pancreatic tumorigenesis through a novel NCX1/Ca(2+)/β-catenin signaling pathway.
Topics: Animals; Antineoplastic Agents; beta Catenin; Calcium Signaling; Carcinoma, Pancreatic Ductal; Cell | 2016 |
Bystander effect on cell growth stimulation in neoplastic HSGc cells induced by heavy-ion irradiation.
Topics: Bystander Effect; Cell Division; Cell Survival; Cell Transformation, Neoplastic; Coculture Technique | 2003 |
Involvement of spermidine in proliferation and differentiation of human promyelocytic leukemia cells.
Topics: Acetamides; Antineoplastic Agents; Cell Line; Cell Transformation, Neoplastic; DNA; Eflornithine; Hu | 1984 |
Polyamine biosynthetic enzymes as targets in cancer chemotherapy.
Topics: Adenine Nucleotides; Animals; Carcinoma, Ehrlich Tumor; Cell Division; Cell Line; Cell Transformatio | 1984 |
Selective killing of transformed cells in combination with inhibitors of polyamine biosynthesis and S-phase specific drugs.
Topics: Cell Division; Cell Transformation, Neoplastic; Cytarabine; Drug Synergism; Eflornithine; HeLa Cells | 1981 |
Regulation of polyamine biosynthesis in normal and transformed hamster cells in culture.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Enzyme Induction; Fibroblasts; Orni | 1980 |
Polyamines and prostatic carcinoma: clinical and therapeutic implications.
Topics: Adult; Aged; Animals; Biomarkers, Tumor; Cell Division; Cell Transformation, Neoplastic; Eflornithin | 1993 |
Regulation of ornithine decarboxylase in a transformed cell line that overexpresses translation initiation factor eIF-4E.
Topics: 3T3 Cells; Animals; Cell Transformation, Neoplastic; Eukaryotic Initiation Factor-4E; Gene Expressio | 1996 |
Polyamines regulate expression of the neoplastic phenotype in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Newborn; Apoptosis; Carcinoma, Papillary; Carcin | 1998 |
The polyamine oxidase inhibitor MDL-72,527 selectively induces apoptosis of transformed hematopoietic cells through lysosomotropic effects.
Topics: Animals; Apoptosis; bcl-X Protein; Cell Cycle; Cell Death; Cell Line, Transformed; Cell Survival; Ce | 1999 |
Nitric oxide mediates apoptosis induction selectively in transformed fibroblasts compared to nontransformed fibroblasts.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Azoles; Biomarkers; Cell Line; Cell Lin | 2002 |
Specific increase in polyamine levels in chick embryo cells transformed by Rous sarcoma virus.
Topics: Allantois; Animals; Avian Sarcoma Viruses; Cell Transformation, Neoplastic; Chick Embryo; Chorion; E | 1975 |
Polyamine metabolism in normal and in virus-transformed chick embryo fibroblasts.
Topics: Avian Sarcoma Viruses; Carboxy-Lyases; Cell Transformation, Neoplastic; Cells, Cultured; Mutation; O | 1975 |
Putrescine transport is greatly increased in human fibroblasts initiated to proliferate.
Topics: Biological Transport; Blood; Bucladesine; Cadaverine; Calcium; Cell Division; Cell Line; Cell Transf | 1976 |
Differential effects of inhibition of polyamine biosynthesis on cell cycle traverse and structure of the prematurely condensed chromosomes of normal and transformed cells.
Topics: Animals; Cell Cycle; Cell Transformation, Neoplastic; Cells, Cultured; Chromosomes; Cricetinae; DNA | 1979 |
Ornithine decarboxylase induction and DNA synthesis in hamster embryo cell cultures treated with tumor-promoting phorbol diesters.
Topics: Carboxy-Lyases; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; DNA; Enzyme Inducti | 1977 |
Seminal polyamines as agents of cervical carcinoma: production of aneuploidy in squamous epithelium.
Topics: Adult; Aneuploidy; Cell Cycle; Cell Line; Cell Transformation, Neoplastic; Cervix Uteri; Diamines; D | 1991 |
The role of polyamines as a marker of tumor progression and regression in experimental tumors.
Topics: Animals; Biomarkers, Tumor; Carcinoma, Ehrlich Tumor; Cell Division; Cell Transformation, Neoplastic | 1990 |
Polyamine involvement in basal and estradiol-stimulated insulin-like growth factor I secretion and action in breast cancer cells in culture.
Topics: Antibodies, Monoclonal; Breast Neoplasms; Cell Transformation, Neoplastic; Eflornithine; Estradiol; | 1990 |
Malondialdehyde production from spermine by homogenates of normal and transformed cells.
Topics: Aldehydes; Amine Oxidase (Copper-Containing); Animals; Cell Line; Cell Transformation, Neoplastic; L | 1987 |
Modulation of polyamine biosynthesis and transport by oncogene transfection.
Topics: Animals; Biological Transport; Cell Division; Cell Line; Cell Transformation, Neoplastic; Eflornithi | 1988 |
Polyamines and tumor cells: effect of transformation of chick embryo fibroblasts by Rous sarcoma virus on polyamine levels.
Topics: Animals; Avian Sarcoma Viruses; Cell Transformation, Neoplastic; Cells, Cultured; Chick Embryo; Chro | 1973 |
Polyamines in normal and in virus-transformed chick embryo fibroblasts.
Topics: Animals; Avian Sarcoma Viruses; Cell Transformation, Neoplastic; Cells, Cultured; Chick Embryo; Cult | 1974 |
Regulation of growth in vitro. I. Control of ornithine decarboxylase levels in untransformed and transformed mouse fibroblasts by serum.
Topics: Animals; Carbon Radioisotopes; Carboxy-Lyases; Cell Transformation, Neoplastic; Cells, Cultured; Cul | 1974 |
A "loop" model for integration of donor DNA into host DNA of eukaryote cells.
Topics: Alleles; Animals; Bromodeoxyuridine; Cell Differentiation; Cell Nucleus; Cell Transformation, Neopla | 1972 |