Page last updated: 2024-10-20

spermine and Carcinoma, Epidermoid

spermine has been researched along with Carcinoma, Epidermoid in 16 studies

Research Excerpts

ExcerptRelevanceReference
" This paper discusses the development of a group of lipophilic polyamine analogues that potently inhibit the cellular polyamine uptake system and greatly increase the effectiveness of polyamine depletion when used in combination with DFMO, a well-studied polyamine biosynthesis inhibitor."1.35Lipophilic lysine-spermine conjugates are potent polyamine transport inhibitors for use in combination with a polyamine biosynthesis inhibitor. ( Burns, MR; Chen, Y; Graminski, GF; O'Brien, TG; Weeks, RS, 2009)
"Xenografts of human squamous cell carcinomas were grown in nude mice; then, BE 4444 was injected intraperitoneally (5 mg/kg) on a twice-daily schedule for 8 days."1.29Growth inhibition of squamous cell carcinoma xenografts with the polyamine analogue BE 4444. ( Auchter, RM; Harari, PM; Nash, GA; Pickart, MA; Qu, RP, 1996)
"All 6 patients with localized malignant tumors had elevated urinary polyamine levels."1.25Urinary polyamine levels in human cancer. ( Kessler, GF; Lipton, A; Sheehan, LM, 1975)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19907 (43.75)18.7374
1990's3 (18.75)18.2507
2000's2 (12.50)29.6817
2010's3 (18.75)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Wu, R1
Zuo, W1
Xu, X1
Bi, L1
Zhang, C1
Chen, H1
Liu, H1
Wang, K1
Huang, Q1
Zhao, G1
Yang, J1
Yang, K1
Huang, Y1
Lewis, JR1
O'Brien, TG4
Skorupski, KA1
Krick, EL1
Reiter, AM1
Jennings, MW1
Jurney, CH1
Shofer, FS1
Kato, M1
Onishi, H1
Matsumoto, K1
Motoshita, J1
Tsuruta, N1
Higuchi, K1
Katano, M1
Burns, MR2
Graminski, GF1
Weeks, RS2
Chen, Y2
Boorman, DW1
Klein-Szanto, A1
Moulinoux, JP1
Quemener, V1
Larzul, JJ1
Le Calve, M1
Roch, AM1
Toujas, L1
Quash, G1
Wilcox, KW1
Kohn, A1
Sklyanskaya, E1
Roizman, B1
Shideler, CE1
Johns, ME1
Cantrell, RW1
Shipe, JR1
Wills, MR1
Savory, J1
Harari, PM2
Pickart, MA2
Contreras, L1
Petereit, DG1
Basu, HS1
Marton, LJ2
Auchter, RM1
Nash, GA1
Qu, RP1
Peralta Soler, A1
Gilliard, G1
Megosh, L1
George, K1
Lipton, A1
Sheehan, LM1
Kessler, GF1
Dimery, IW1
Nishioka, K1
Grossie, VB1
Ota, DM1
Schantz, SP1
Byers, R1
Robbins, KT1
Hong, WK1
Shukla, GS1
Singhal, RL1
Russell, DH1
Levy, CC1

Other Studies

16 other studies available for spermine and Carcinoma, Epidermoid

ArticleYear
MCU That Is Transcriptionally Regulated by Nrf2 Augments Malignant Biological Behaviors in Oral Squamous Cell Carcinoma Cells.
    BioMed research international, 2021, Volume: 2021

    Topics: Apoptosis; Calcium Channels; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Cell Prolife

2021
Gene polymorphisms of SFTPB rs7316, rs9752 and PAOX rs1046175 affect the diagnostic value of plasma Pro-SFTPB and DAS in Chinese Han non-small-cell lung cancer patients.
    Journal of cellular biochemistry, 2019, Volume: 120, Issue:9

    Topics: Adenocarcinoma of Lung; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Carcinoma, Non-Small-Cell

2019
Polyamine inhibitors for treatment of feline oral squamous cell carcinoma: a proof-of-concept study.
    Journal of veterinary dentistry, 2013,Fall, Volume: 30, Issue:3

    Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cat Diseases; Cats; Eflornithine; Evoked P

2013
Prognostic significance of urine N1, N12-diacetylspermine in patients with non-small cell lung cancer.
    Anticancer research, 2014, Volume: 34, Issue:6

    Topics: Adenocarcinoma; Aged; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; F

2014
Lipophilic lysine-spermine conjugates are potent polyamine transport inhibitors for use in combination with a polyamine biosynthesis inhibitor.
    Journal of medicinal chemistry, 2009, Apr-09, Volume: 52, Issue:7

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biological Transport

2009
Combination therapy with 2-difluoromethylornithine and a polyamine transport inhibitor against murine squamous cell carcinoma.
    International journal of cancer, 2006, May-01, Volume: 118, Issue:9

    Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Squamous Cell; Drug Therapy, Combination; Eflo

2006
Red blood cell polyamines in mice bearing the Lewis lung carcinoma (3LL) and in patients with bronchopulmonary cancers.
    International journal of cancer, 1984, Aug-15, Volume: 34, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Animals; Bronchial Neoplasms; Carcinoma, Small Cell; Carcinoma, Squamou

1984
Herpes simplex virus phosphoproteins. I. Phosphate cycles on and off some viral polypeptides and can alter their affinity for DNA.
    Journal of virology, 1980, Volume: 33, Issue:1

    Topics: Carcinoma, Squamous Cell; Cell Line; Cycloheximide; DNA, Viral; Heparin; Humans; Laryngeal Neoplasms

1980
Erythrocyte polyamine determinations in patients with head and neck cancer.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1981, Volume: 107, Issue:12

    Topics: Carcinoma, Squamous Cell; Erythrocytes; Head and Neck Neoplasms; Humans; Polyamines; Spermidine; Spe

1981
Slowing proliferation in head and neck tumors: in vitro growth inhibitory effects of the polyamine analog BE-4-4-4-4 in human squamous cell carcinomas.
    International journal of radiation oncology, biology, physics, 1995, Jun-15, Volume: 32, Issue:3

    Topics: Carcinoma, Squamous Cell; Cell Cycle; Cell Division; Drug Screening Assays, Antitumor; Flow Cytometr

1995
Growth inhibition of squamous cell carcinoma xenografts with the polyamine analogue BE 4444.
    Archives of otolaryngology--head & neck surgery, 1996, Volume: 122, Issue:9

    Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Division; Cell Line; Drug Screening A

1996
Polyamines regulate expression of the neoplastic phenotype in mouse skin.
    Cancer research, 1998, Apr-15, Volume: 58, Issue:8

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Newborn; Apoptosis; Carcinoma, Papillary; Carcin

1998
Urinary polyamine levels in human cancer.
    Cancer, 1975, Volume: 35, Issue:2

    Topics: Adenocarcinoma; Adenoma; Bone Neoplasms; Breast Neoplasms; Bronchial Neoplasms; Carcinoma, Squamous

1975
Polyamine metabolism in carcinoma of the oral cavity compared with adjacent and normal oral mucosa.
    American journal of surgery, 1987, Volume: 154, Issue:4

    Topics: Carcinoma, Squamous Cell; Female; Humans; Male; Middle Aged; Mouth Mucosa; Mouth Neoplasms; Ornithin

1987
Hormone-independent polyamine metabolism of squamous cell carcinoma of the prostate.
    Cell biochemistry and function, 1985, Volume: 3, Issue:3

    Topics: Adenosylmethionine Decarboxylase; Androgens; Animals; Carcinoma, Squamous Cell; Castration; Cyproter

1985
Measurement of putrescine, spermidine, and spermine in physiological fluids by use of an amino acid analyzer.
    Clinical chemistry, 1973, Volume: 19, Issue:8

    Topics: Autoanalysis; Carbon Isotopes; Carcinoma, Squamous Cell; Chromatography, Ion Exchange; Humans; Lung

1973