spermine has been researched along with Benign Neoplasms, Brain in 48 studies
Excerpt | Relevance | Reference |
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" By employing RT-PCR and Western blotting techniques, we have examined the HO-1 induction in C6 glioma cells that were treated with cadmium chloride (CdCl(2)) or spermine NONOate (SPER/NO)." | 7.73 | Heme oxygenase-1-mediated partial cytoprotective effect by NO on cadmium-induced cytotoxicity in C6 rat glioma cells. ( Cha, SH; Cha, YN; Jung, NH; Kim, BR; Kim, HS; Srisook, K, 2005) |
" By employing RT-PCR and Western blotting techniques, we have examined the HO-1 induction in C6 glioma cells that were treated with cadmium chloride (CdCl(2)) or spermine NONOate (SPER/NO)." | 3.73 | Heme oxygenase-1-mediated partial cytoprotective effect by NO on cadmium-induced cytotoxicity in C6 rat glioma cells. ( Cha, SH; Cha, YN; Jung, NH; Kim, BR; Kim, HS; Srisook, K, 2005) |
"This 52-year-old male without a significant medical history was receiving chemotherapy with diethylnorspermine (DENSPM), a polyamine analogue, for a partially resected pancreatic adenocarcinoma." | 3.70 | Chemotherapy for pancreatic cancer: a neuroimaging clinicopathologic correlation. ( Rojiani, AM; Valenstein, EJ; Williams, LS, 1999) |
"In these primary brain tumors changes in urinary DiAcSpm were well correlated with the efficacy of treatments, recurrence of disease and increased malignancy of a tumor." | 2.43 | [Urinary diacetylspermine: its analysis and performance as a novel tumor marker]. ( Hiramatsu, K; Kariyone, K; Kawaguchi, M; Kawakita, M; Mori, T; Sasaki, Y; Shinoura, N; Takahashi, K; Tamamori, Y; Tanaka, T; Yamada, R, 2005) |
"The SF-767 brain tumors were extremely responsive to BE-4-4-4-4 alone (3 of 8 complete regressions after 2 cycles); however, the growth of the U-87 MG brain tumor was only slightly inhibited by BE-4-4-4-4 treatment." | 1.29 | Effect of 1,19-bis(ethylamino)-5,10,15-triazanonadecane on human tumor xenografts. ( Basu, HS; Casero, RA; Dolan, ME; Feuerstein, BG; Fleig, MJ; Luk, GD; Marton, LJ, 1994) |
"In the other primary brain tumors, however, the relationship between levels of N1-AcSpd in tissue and biological malignancy should be examined in each histopathological type." | 1.29 | Relationship between tissue polyamine levels and malignancy in primary brain tumors. ( Kurihara, H; Matsuzaki, S; Tamura, M; Tsukahara, T; Yamazaki, H, 1993) |
"Putrescine level was significantly increased in children with medulloblastomas." | 1.27 | CSF polyamines in childhood. ( Albright, AL; Lubich, WP; Marton, LJ; Reigel, DH, 1983) |
"CSF putrescine values were closely correlated with clinical state, with the highest concentrations identified in patients with widely disseminated recurrent disease." | 1.27 | Cerebrospinal fluid polyamines: biochemical markers of malignant childhood brain tumors. ( De Vivo, DC; Kremzner, LT; Phillips, PC, 1986) |
"Putrescine levels were elevated in all astrocytomas assayed, and the magnitude of this elevation was proportional to the malignancy of the tumor as determined by histopathological criteria." | 1.26 | Putrescine as a biochemical marker of malignant brain tumors. ( Harik, SI; Sutton, CH, 1979) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 27 (56.25) | 18.7374 |
1990's | 16 (33.33) | 18.2507 |
2000's | 4 (8.33) | 29.6817 |
2010's | 1 (2.08) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Cai, J | 2 |
Soloway, AH | 2 |
Barth, RF | 2 |
Adams, DM | 2 |
Hariharan, JR | 1 |
Wyzlic, IM | 1 |
Radcliffe, K | 1 |
Zhuo, JC | 1 |
Ji, W | 1 |
Tjarks, W | 1 |
Tian, Y | 1 |
Wang, S | 1 |
Wang, B | 1 |
Zhang, J | 1 |
Jiang, R | 1 |
Zhang, W | 1 |
Bai, H | 1 |
Konat, GW | 1 |
Dot, J | 1 |
Lluch, M | 1 |
Blanco, I | 1 |
Rodríguez-Alvarez, J | 1 |
Srisook, K | 1 |
Jung, NH | 1 |
Kim, BR | 1 |
Cha, SH | 1 |
Kim, HS | 1 |
Cha, YN | 1 |
Kawakita, M | 1 |
Hiramatsu, K | 1 |
Takahashi, K | 1 |
Yamada, R | 1 |
Kawaguchi, M | 1 |
Shinoura, N | 1 |
Tanaka, T | 1 |
Kariyone, K | 1 |
Tamamori, Y | 1 |
Sasaki, Y | 1 |
Mori, T | 1 |
Marton, LJ | 24 |
Fujita, K | 1 |
Shinpo, K | 1 |
Nagatsu, T | 1 |
Oredsson, SM | 2 |
Gray, JW | 3 |
Hung, DT | 1 |
Pegg, AE | 1 |
Deen, DF | 8 |
Seidenfeld, J | 5 |
Albright, AL | 1 |
Lubich, WP | 2 |
Reigel, DH | 1 |
Bergeron, CJ | 1 |
Basu, HS | 7 |
Pellarin, M | 5 |
Feuerstein, BG | 7 |
Smirnov, IV | 1 |
Dolan, ME | 1 |
Fleig, MJ | 1 |
Luk, GD | 1 |
Casero, RA | 1 |
Chen, CZ | 1 |
Hu, LJ | 1 |
Bergeron, RJ | 2 |
Shirahata, A | 1 |
Samejima, K | 1 |
Ernestus, RI | 2 |
Röhn, G | 2 |
Hossmann, KA | 1 |
Paschen, W | 2 |
Kurihara, H | 1 |
Matsuzaki, S | 2 |
Yamazaki, H | 2 |
Tsukahara, T | 2 |
Tamura, M | 1 |
Schröder, R | 1 |
Els, T | 1 |
Lee, JY | 1 |
Klug, N | 1 |
Watanabe, S | 1 |
Sato, S | 1 |
Nagase, S | 1 |
Shimosato, K | 1 |
Ohkuma, S | 1 |
Rojiani, AM | 1 |
Williams, LS | 1 |
Valenstein, EJ | 1 |
Bodell, WJ | 1 |
Harik, SI | 1 |
Sutton, CH | 1 |
Levin, VA | 2 |
Devor, WN | 1 |
Terabayashi, T | 2 |
Heby, O | 6 |
Wilson, CB | 5 |
Tanimura, K | 1 |
Ueki, K | 1 |
Martinez, HM | 1 |
Lee, PL | 2 |
Crafts, DC | 1 |
Sturkenboom, MC | 1 |
Delcros, JG | 1 |
Csokan, PP | 1 |
Szollosi, J | 1 |
Elworthy, P | 1 |
Hitchcock, E | 1 |
Phillips, PC | 1 |
Kremzner, LT | 2 |
De Vivo, DC | 1 |
Goldman, SS | 1 |
Volkow, ND | 1 |
Brodie, J | 1 |
Flamm, ES | 1 |
Scalabrino, G | 1 |
Ferioli, ME | 1 |
Luccarelli, G | 1 |
Uki, J | 1 |
Russell, DH | 1 |
Levy, CC | 1 |
Schimpff, SC | 1 |
Hawk, IA | 1 |
Duffy, PE | 1 |
Defendini, R | 1 |
3 reviews available for spermine and Benign Neoplasms, Brain
Article | Year |
---|---|
[Urinary diacetylspermine: its analysis and performance as a novel tumor marker].
Topics: Biomarkers, Tumor; Brain Neoplasms; Chromatography, High Pressure Liquid; Colonic Neoplasms; Enzyme- | 2005 |
[Polyamines and cancers (author's transl)].
Topics: Adult; Animals; Brain Neoplasms; Child; Erythrocytes; Female; Humans; Male; Mice; Neoplasms; Neoplas | 1981 |
Polyamine biosynthesis in primary tumors of human central nervous system: review of current knowledge.
Topics: Adenosylmethionine Decarboxylase; Brain Neoplasms; Erythrocytes; Humans; Ornithine Decarboxylase; Po | 1985 |
45 other studies available for spermine and Benign Neoplasms, Brain
Article | Year |
---|---|
Boron-containing polyamines as DNA targeting agents for neutron capture therapy of brain tumors: synthesis and biological evaluation.
Topics: Animals; Antineoplastic Agents; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; DNA | 1997 |
Synthesis and biological evaluation of boron-containing polyamines as potential agents for neutron capture therapy of brain tumors.
Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cattle; DNA; Glioma; Melan | 1999 |
Overexpression of SSAT by DENSPM treatment induces cell detachment and apoptosis in glioblastoma.
Topics: Acetyltransferases; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Adhesion; Cell Line, Tum | 2012 |
Hydrogen peroxide mediates higher order chromatin degradation.
Topics: Animals; Brain Neoplasms; Cell Nucleus; Chromatin; DNA; Glioma; Hydrogen Peroxide; Hypochlorous Acid | 2003 |
Polyamine uptake in cultured cerebellar granule neurons.
Topics: Animals; Astrocytes; Biogenic Polyamines; Brain Neoplasms; Cell Line, Tumor; Cells, Cultured; Cerebe | 2004 |
Heme oxygenase-1-mediated partial cytoprotective effect by NO on cadmium-induced cytotoxicity in C6 rat glioma cells.
Topics: Animals; Brain Neoplasms; Cadmium; Cell Line, Tumor; Cell Survival; Cytoprotection; Dose-Response Re | 2005 |
CSF polyamines. Potential as brain tumor markers.
Topics: Astrocytoma; Brain Neoplasms; Cerebellar Neoplasms; Glioblastoma; Humans; Medulloblastoma; Polyamine | 1981 |
Progressive increase in polyamine levels in 9L cells in vitro during the cell cycle: comparison between cells isolated by centrifugal elutriation and cells grown in synchrony.
Topics: Animals; Brain Neoplasms; Cell Cycle; Cell Line; Centrifugation; Kinetics; Polyamines; Putrescine; R | 1984 |
Potentiation of 1,3-bis(2-chloroethyl)-1-nitrosourea cytotoxicity in 9L rat brain tumor cells by methylglyoxal-bis(guanylhydrazone), an inhibitor of S-adenosyl-L-methionine decarboxylase.
Topics: Adenosylmethionine Decarboxylase; Animals; Brain Neoplasms; Carboxy-Lyases; Carmustine; Cell Surviva | 1984 |
Depletion of intracellular polyamine content does not alter the survival of 9L rat brain tumour cells after X-irradiation.
Topics: Animals; Brain Neoplasms; Cell Line; Cell Survival; Cells, Cultured; DNA; DNA, Neoplasm; Eflornithin | 1980 |
Depletion of 9L rat brain tumor cell polyamine content by treatment with D,L-alpha-difluoromethylornithine inhibits proliferation and the G1 to S transition.
Topics: Animals; Brain Neoplasms; Cell Division; Cell Line; Dose-Response Relationship, Drug; Eflornithine; | 1981 |
CSF polyamines in childhood.
Topics: Age Factors; Brain Neoplasms; Child; Child, Preschool; Encephalocele; Humans; Hydrocephalus; Meningo | 1983 |
Effects of DL-alpha-methylornithine on proliferation and polyamine content of 9L rat brain tumor cells.
Topics: Animals; Brain Neoplasms; Carboxy-Lyases; Cell Division; Cells, Cultured; Neoplasms, Experimental; O | 1980 |
Two polyamine analogs (BE-4-4-4 and BE-4-4-4-4) directly affect growth, survival, and cell cycle progression in two human brain tumor cell lines.
Topics: Antineoplastic Agents; Brain Neoplasms; Flow Cytometry; Growth Inhibitors; Humans; Spermine; Tumor C | 1995 |
Pretreatment with the polyamine analog 1,19-bis-(ethylamino)-5,10,15-triazanonadecane (BE-4-4-4-4) inhibits etoposide cytotoxicity in U-251 MG (NCI) human brain tumor cells.
Topics: Brain Neoplasms; Cell Death; Cell Division; DNA, Neoplasm; Etoposide; Humans; Nuclear Matrix; Spermi | 1994 |
Effect of 1,19-bis(ethylamino)-5,10,15-triazanonadecane on human tumor xenografts.
Topics: Animals; Body Weight; Brain Neoplasms; Carmustine; Cell Division; Colonic Neoplasms; Drug Screening | 1994 |
Radiopotentiation of human brain tumor cells by the spermine analog N1,N14-bis(ethyl)homospermine.
Topics: Brain Neoplasms; Combined Modality Therapy; Humans; Polyamines; Radiation-Sensitizing Agents; Spermi | 1994 |
Interaction of a polyamine analogue, 1,19-bis-(ethylamino)-5,10,15- triazanonadecane (BE-4-4-4-4), with DNA and effect on growth, survival, and polyamine levels in seven human brain tumor cell lines.
Topics: Brain Neoplasms; Cell Division; Cell Survival; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug | 1993 |
Polyamine metabolism in experimental brain tumors of rat.
Topics: Animals; Brain; Brain Neoplasms; Clone Cells; Functional Laterality; Glioma; Male; Organ Specificity | 1993 |
Relationship between tissue polyamine levels and malignancy in primary brain tumors.
Topics: Adolescent; Adult; Aged; Biomarkers, Tumor; Brain; Brain Neoplasms; Child; Child, Preschool; Chromat | 1993 |
Polyamine metabolism in gliomas.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Astrocytoma; Brain Neoplasms; Child; Child, Preschool; F | 1996 |
Choice of vincristine or 6-mercaptopurine on the basis of polyamine level in tumor-bearing regions of the brain.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Chroma | 1999 |
Chemotherapy for pancreatic cancer: a neuroimaging clinicopathologic correlation.
Topics: Adenocarcinoma; Antineoplastic Agents; Brain; Brain Neoplasms; Demyelinating Diseases; Diagnosis, Di | 1999 |
Effect of cations on the formation of DNA alkylation products in DNA reacted with 1-(2-Chloroethyl)-1-nitrosourea.
Topics: Alkylating Agents; Alkylation; Animals; Brain Neoplasms; Cations; Cattle; Chromatography, High Press | 1999 |
Putrescine as a biochemical marker of malignant brain tumors.
Topics: Astrocytoma; Brain Chemistry; Brain Neoplasms; Glioblastoma; Humans; Neoplasms, Nerve Tissue; Putres | 1979 |
Kinetics and distribution of tritiated putrescine in the domestic cat.
Topics: Animals; Astrocytoma; Brain Neoplasms; Cats; Dose-Response Relationship, Drug; Glioblastoma; Kinetic | 1979 |
[Measurement of blood polyamines in patients with brain tumor--special reference to relationship between the blood levels of spermidine and spermine, and histological malignancy in patients with glioma (author's transl)].
Topics: Adenoma; Adolescent; Adult; Astrocytoma; Brain Neoplasms; Ependymoma; Glioma; Hemangiosarcoma; Human | 1977 |
Depletion of intracellular putrescine and spermidine by alpha-difluromethylornithine does not inhibit proliferation of 9L rat brain tumor cells.
Topics: Animals; Brain Neoplasms; Carboxy-Lyases; Cell Division; Depression, Chemical; Dose-Response Relatio | 1979 |
Effect of methylglyoxal-bis (guanylhydrazone), an inhibitor of spermidine and spermine synthesis, on cell cycle traverse.
Topics: Animals; Brain Neoplasms; Cell Cycle; Cells, Cultured; Guanidines; Mitoguazone; Putrescine; Rats; Sp | 1977 |
[Determination of blood polyamines in patients with brain tumor -with special reference to relationship between varieties of tumors and concentrations of blood spermidine and spermine (author's transl)].
Topics: Adult; Brain Neoplasms; Female; Glioma; Humans; Male; Meningioma; Middle Aged; Neurilemmoma; Pinealo | 1976 |
Polyamines: a high correlation with cell replication.
Topics: Animals; Brain Neoplasms; Cell Division; Cell Line; Cells, Cultured; DNA, Neoplasm; Nitrosourea Comp | 1975 |
More sensitive automated detection of polyamines in physiological fluids and tissue extracts with omicron-phthalaldehyde.
Topics: Aldehydes; Amniotic Fluid; Animals; Autoanalysis; Brain Neoplasms; Evaluation Studies as Topic; Fema | 1975 |
The relationship of polyamines in cerebrospinal fluid to the presence of central nervous system tumors.
Topics: Adenoma; Astrocytoma; Brain Neoplasms; Central Nervous System Diseases; Glioma; Humans; Medulloblast | 1976 |
Effect of polyamine depletion on chromatin structure in U-87 MG human brain tumour cells.
Topics: Brain Neoplasms; Cell Nucleus; Chromatin; Culture Media, Serum-Free; Deoxyribonuclease I; Eflornithi | 1992 |
Effect on N1,N14-bis-(ethyl)-homospermine (BE-4-4-4) on the growth of U-251 MG and SF-188 human brain tumor cells.
Topics: Antineoplastic Agents; Brain Neoplasms; Cell Line; Cell Survival; Humans; Kinetics; Polyamines; Putr | 1991 |
Effect of N1,N14-bis(ethyl)homospermine on the growth of U-87 MG and SF-126 human brain tumor cells.
Topics: Brain Neoplasms; Cell Division; Humans; Putrescine; Spermidine; Spermine; Tumor Cells, Cultured | 1990 |
Red blood cell polyamines as a diagnostic indicator of glioma presence and recurrence.
Topics: Adolescent; Adult; Aged; Brain Neoplasms; Child; Child, Preschool; Female; Glioma; Humans; Male; Mid | 1989 |
Cerebrospinal fluid polyamines: biochemical markers of malignant childhood brain tumors.
Topics: Adolescent; Astrocytoma; Brain Neoplasms; Child; Child, Preschool; Humans; Medulloblastoma; Neoplasm | 1986 |
Putrescine metabolism in human brain tumors.
Topics: Astrocytoma; Brain Neoplasms; Humans; In Vitro Techniques; Meningioma; Neurilemmoma; Putrescine; Spe | 1986 |
Elevated levels of free putrescine and N1-acetylspermidine in cyst fluids of malignant brain tumours.
Topics: Brain; Brain Neoplasms; Cysts; Humans; Putrescine; Spermidine; Spermine | 1986 |
Increased polyamine concentrations in the cerebrospinal fluid of patients with brain tumors.
Topics: Adenoma, Acidophil; Adenoma, Chromophobe; Adolescent; Adult; Aged; Astrocytoma; Brain Neoplasms; Cer | 1974 |
Polyamine metabolism in tumor, spleen and liver of tumor-bearing rats.
Topics: Animals; Body Weight; Brain Neoplasms; Carbon Radioisotopes; Carboxy-Lyases; Liver; Male; Neoplasm T | 1974 |
An automated micromethod for the quantitative analysis of di- and polyamines utilizing a sensitive high pressure liquid chromatographic procedure.
Topics: Animals; Autoanalysis; Brain; Brain Chemistry; Brain Neoplasms; Cadaverine; Carbon Radioisotopes; Ch | 1974 |
Urinary polyamines in cancer patients.
Topics: Brain Neoplasms; Chemistry, Clinical; Daunorubicin; Female; Hodgkin Disease; Humans; Leukemia, Lymph | 1971 |
Regulation of meningioma cell growth in vitro by polyamines.
Topics: Biopsy; Brain Neoplasms; Butylamines; Cell Count; Cells, Cultured; Culture Media; Culture Techniques | 1971 |