Compounds > spermine
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spermine and Benign Neoplasms, Brain

spermine has been researched along with Benign Neoplasms, Brain in 48 studies

Research Excerpts

ExcerptRelevanceReference
" By employing RT-PCR and Western blotting techniques, we have examined the HO-1 induction in C6 glioma cells that were treated with cadmium chloride (CdCl(2)) or spermine NONOate (SPER/NO)."7.73Heme oxygenase-1-mediated partial cytoprotective effect by NO on cadmium-induced cytotoxicity in C6 rat glioma cells. ( Cha, SH; Cha, YN; Jung, NH; Kim, BR; Kim, HS; Srisook, K, 2005)
" By employing RT-PCR and Western blotting techniques, we have examined the HO-1 induction in C6 glioma cells that were treated with cadmium chloride (CdCl(2)) or spermine NONOate (SPER/NO)."3.73Heme oxygenase-1-mediated partial cytoprotective effect by NO on cadmium-induced cytotoxicity in C6 rat glioma cells. ( Cha, SH; Cha, YN; Jung, NH; Kim, BR; Kim, HS; Srisook, K, 2005)
"This 52-year-old male without a significant medical history was receiving chemotherapy with diethylnorspermine (DENSPM), a polyamine analogue, for a partially resected pancreatic adenocarcinoma."3.70Chemotherapy for pancreatic cancer: a neuroimaging clinicopathologic correlation. ( Rojiani, AM; Valenstein, EJ; Williams, LS, 1999)
"In these primary brain tumors changes in urinary DiAcSpm were well correlated with the efficacy of treatments, recurrence of disease and increased malignancy of a tumor."2.43[Urinary diacetylspermine: its analysis and performance as a novel tumor marker]. ( Hiramatsu, K; Kariyone, K; Kawaguchi, M; Kawakita, M; Mori, T; Sasaki, Y; Shinoura, N; Takahashi, K; Tamamori, Y; Tanaka, T; Yamada, R, 2005)
"The SF-767 brain tumors were extremely responsive to BE-4-4-4-4 alone (3 of 8 complete regressions after 2 cycles); however, the growth of the U-87 MG brain tumor was only slightly inhibited by BE-4-4-4-4 treatment."1.29Effect of 1,19-bis(ethylamino)-5,10,15-triazanonadecane on human tumor xenografts. ( Basu, HS; Casero, RA; Dolan, ME; Feuerstein, BG; Fleig, MJ; Luk, GD; Marton, LJ, 1994)
"In the other primary brain tumors, however, the relationship between levels of N1-AcSpd in tissue and biological malignancy should be examined in each histopathological type."1.29Relationship between tissue polyamine levels and malignancy in primary brain tumors. ( Kurihara, H; Matsuzaki, S; Tamura, M; Tsukahara, T; Yamazaki, H, 1993)
"Putrescine level was significantly increased in children with medulloblastomas."1.27CSF polyamines in childhood. ( Albright, AL; Lubich, WP; Marton, LJ; Reigel, DH, 1983)
"CSF putrescine values were closely correlated with clinical state, with the highest concentrations identified in patients with widely disseminated recurrent disease."1.27Cerebrospinal fluid polyamines: biochemical markers of malignant childhood brain tumors. ( De Vivo, DC; Kremzner, LT; Phillips, PC, 1986)
"Putrescine levels were elevated in all astrocytomas assayed, and the magnitude of this elevation was proportional to the malignancy of the tumor as determined by histopathological criteria."1.26Putrescine as a biochemical marker of malignant brain tumors. ( Harik, SI; Sutton, CH, 1979)

Research

Studies (48)

TimeframeStudies, this research(%)All Research%
pre-199027 (56.25)18.7374
1990's16 (33.33)18.2507
2000's4 (8.33)29.6817
2010's1 (2.08)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cai, J2
Soloway, AH2
Barth, RF2
Adams, DM2
Hariharan, JR1
Wyzlic, IM1
Radcliffe, K1
Zhuo, JC1
Ji, W1
Tjarks, W1
Tian, Y1
Wang, S1
Wang, B1
Zhang, J1
Jiang, R1
Zhang, W1
Bai, H1
Konat, GW1
Dot, J1
Lluch, M1
Blanco, I1
Rodríguez-Alvarez, J1
Srisook, K1
Jung, NH1
Kim, BR1
Cha, SH1
Kim, HS1
Cha, YN1
Kawakita, M1
Hiramatsu, K1
Takahashi, K1
Yamada, R1
Kawaguchi, M1
Shinoura, N1
Tanaka, T1
Kariyone, K1
Tamamori, Y1
Sasaki, Y1
Mori, T1
Marton, LJ24
Fujita, K1
Shinpo, K1
Nagatsu, T1
Oredsson, SM2
Gray, JW3
Hung, DT1
Pegg, AE1
Deen, DF8
Seidenfeld, J5
Albright, AL1
Lubich, WP2
Reigel, DH1
Bergeron, CJ1
Basu, HS7
Pellarin, M5
Feuerstein, BG7
Smirnov, IV1
Dolan, ME1
Fleig, MJ1
Luk, GD1
Casero, RA1
Chen, CZ1
Hu, LJ1
Bergeron, RJ2
Shirahata, A1
Samejima, K1
Ernestus, RI2
Röhn, G2
Hossmann, KA1
Paschen, W2
Kurihara, H1
Matsuzaki, S2
Yamazaki, H2
Tsukahara, T2
Tamura, M1
Schröder, R1
Els, T1
Lee, JY1
Klug, N1
Watanabe, S1
Sato, S1
Nagase, S1
Shimosato, K1
Ohkuma, S1
Rojiani, AM1
Williams, LS1
Valenstein, EJ1
Bodell, WJ1
Harik, SI1
Sutton, CH1
Levin, VA2
Devor, WN1
Terabayashi, T2
Heby, O6
Wilson, CB5
Tanimura, K1
Ueki, K1
Martinez, HM1
Lee, PL2
Crafts, DC1
Sturkenboom, MC1
Delcros, JG1
Csokan, PP1
Szollosi, J1
Elworthy, P1
Hitchcock, E1
Phillips, PC1
Kremzner, LT2
De Vivo, DC1
Goldman, SS1
Volkow, ND1
Brodie, J1
Flamm, ES1
Scalabrino, G1
Ferioli, ME1
Luccarelli, G1
Uki, J1
Russell, DH1
Levy, CC1
Schimpff, SC1
Hawk, IA1
Duffy, PE1
Defendini, R1

Reviews

3 reviews available for spermine and Benign Neoplasms, Brain

ArticleYear
[Urinary diacetylspermine: its analysis and performance as a novel tumor marker].
    Rinsho byori. The Japanese journal of clinical pathology, 2005, Volume: 53, Issue:2

    Topics: Biomarkers, Tumor; Brain Neoplasms; Chromatography, High Pressure Liquid; Colonic Neoplasms; Enzyme-

2005
[Polyamines and cancers (author's transl)].
    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1981, Volume: 26, Issue:11

    Topics: Adult; Animals; Brain Neoplasms; Child; Erythrocytes; Female; Humans; Male; Mice; Neoplasms; Neoplas

1981
Polyamine biosynthesis in primary tumors of human central nervous system: review of current knowledge.
    Progress in neurobiology, 1985, Volume: 25, Issue:4

    Topics: Adenosylmethionine Decarboxylase; Brain Neoplasms; Erythrocytes; Humans; Ornithine Decarboxylase; Po

1985

Other Studies

45 other studies available for spermine and Benign Neoplasms, Brain

ArticleYear
Boron-containing polyamines as DNA targeting agents for neutron capture therapy of brain tumors: synthesis and biological evaluation.
    Journal of medicinal chemistry, 1997, Nov-21, Volume: 40, Issue:24

    Topics: Animals; Antineoplastic Agents; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; DNA

1997
Synthesis and biological evaluation of boron-containing polyamines as potential agents for neutron capture therapy of brain tumors.
    Journal of medicinal chemistry, 1999, Apr-08, Volume: 42, Issue:7

    Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cattle; DNA; Glioma; Melan

1999
Overexpression of SSAT by DENSPM treatment induces cell detachment and apoptosis in glioblastoma.
    Oncology reports, 2012, Volume: 27, Issue:4

    Topics: Acetyltransferases; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Adhesion; Cell Line, Tum

2012
Hydrogen peroxide mediates higher order chromatin degradation.
    Neurochemistry international, 2003, Volume: 42, Issue:2

    Topics: Animals; Brain Neoplasms; Cell Nucleus; Chromatin; DNA; Glioma; Hydrogen Peroxide; Hypochlorous Acid

2003
Polyamine uptake in cultured cerebellar granule neurons.
    Neurochemistry international, 2004, Volume: 44, Issue:7

    Topics: Animals; Astrocytes; Biogenic Polyamines; Brain Neoplasms; Cell Line, Tumor; Cells, Cultured; Cerebe

2004
Heme oxygenase-1-mediated partial cytoprotective effect by NO on cadmium-induced cytotoxicity in C6 rat glioma cells.
    Toxicology in vitro : an international journal published in association with BIBRA, 2005, Volume: 19, Issue:1

    Topics: Animals; Brain Neoplasms; Cadmium; Cell Line, Tumor; Cell Survival; Cytoprotection; Dose-Response Re

2005
CSF polyamines. Potential as brain tumor markers.
    Archives of neurology, 1981, Volume: 38, Issue:2

    Topics: Astrocytoma; Brain Neoplasms; Cerebellar Neoplasms; Glioblastoma; Humans; Medulloblastoma; Polyamine

1981
Progressive increase in polyamine levels in 9L cells in vitro during the cell cycle: comparison between cells isolated by centrifugal elutriation and cells grown in synchrony.
    Cell and tissue kinetics, 1984, Volume: 17, Issue:5

    Topics: Animals; Brain Neoplasms; Cell Cycle; Cell Line; Centrifugation; Kinetics; Polyamines; Putrescine; R

1984
Potentiation of 1,3-bis(2-chloroethyl)-1-nitrosourea cytotoxicity in 9L rat brain tumor cells by methylglyoxal-bis(guanylhydrazone), an inhibitor of S-adenosyl-L-methionine decarboxylase.
    European journal of cancer & clinical oncology, 1984, Volume: 20, Issue:3

    Topics: Adenosylmethionine Decarboxylase; Animals; Brain Neoplasms; Carboxy-Lyases; Carmustine; Cell Surviva

1984
Depletion of intracellular polyamine content does not alter the survival of 9L rat brain tumour cells after X-irradiation.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1980, Volume: 38, Issue:2

    Topics: Animals; Brain Neoplasms; Cell Line; Cell Survival; Cells, Cultured; DNA; DNA, Neoplasm; Eflornithin

1980
Depletion of 9L rat brain tumor cell polyamine content by treatment with D,L-alpha-difluoromethylornithine inhibits proliferation and the G1 to S transition.
    Experimental cell research, 1981, Volume: 131, Issue:1

    Topics: Animals; Brain Neoplasms; Cell Division; Cell Line; Dose-Response Relationship, Drug; Eflornithine;

1981
CSF polyamines in childhood.
    Archives of neurology, 1983, Volume: 40, Issue:4

    Topics: Age Factors; Brain Neoplasms; Child; Child, Preschool; Encephalocele; Humans; Hydrocephalus; Meningo

1983
Effects of DL-alpha-methylornithine on proliferation and polyamine content of 9L rat brain tumor cells.
    Cancer research, 1980, Volume: 40, Issue:6

    Topics: Animals; Brain Neoplasms; Carboxy-Lyases; Cell Division; Cells, Cultured; Neoplasms, Experimental; O

1980
Two polyamine analogs (BE-4-4-4 and BE-4-4-4-4) directly affect growth, survival, and cell cycle progression in two human brain tumor cell lines.
    Cancer chemotherapy and pharmacology, 1995, Volume: 36, Issue:5

    Topics: Antineoplastic Agents; Brain Neoplasms; Flow Cytometry; Growth Inhibitors; Humans; Spermine; Tumor C

1995
Pretreatment with the polyamine analog 1,19-bis-(ethylamino)-5,10,15-triazanonadecane (BE-4-4-4-4) inhibits etoposide cytotoxicity in U-251 MG (NCI) human brain tumor cells.
    Cellular and molecular biology (Noisy-le-Grand, France), 1994, Volume: 40, Issue:7

    Topics: Brain Neoplasms; Cell Death; Cell Division; DNA, Neoplasm; Etoposide; Humans; Nuclear Matrix; Spermi

1994
Effect of 1,19-bis(ethylamino)-5,10,15-triazanonadecane on human tumor xenografts.
    Cancer research, 1994, Sep-01, Volume: 54, Issue:17

    Topics: Animals; Body Weight; Brain Neoplasms; Carmustine; Cell Division; Colonic Neoplasms; Drug Screening

1994
Radiopotentiation of human brain tumor cells by the spermine analog N1,N14-bis(ethyl)homospermine.
    International journal of radiation oncology, biology, physics, 1994, Jul-30, Volume: 29, Issue:5

    Topics: Brain Neoplasms; Combined Modality Therapy; Humans; Polyamines; Radiation-Sensitizing Agents; Spermi

1994
Interaction of a polyamine analogue, 1,19-bis-(ethylamino)-5,10,15- triazanonadecane (BE-4-4-4-4), with DNA and effect on growth, survival, and polyamine levels in seven human brain tumor cell lines.
    Cancer research, 1993, Sep-01, Volume: 53, Issue:17

    Topics: Brain Neoplasms; Cell Division; Cell Survival; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug

1993
Polyamine metabolism in experimental brain tumors of rat.
    Journal of neurochemistry, 1993, Volume: 60, Issue:2

    Topics: Animals; Brain; Brain Neoplasms; Clone Cells; Functional Laterality; Glioma; Male; Organ Specificity

1993
Relationship between tissue polyamine levels and malignancy in primary brain tumors.
    Neurosurgery, 1993, Volume: 32, Issue:3

    Topics: Adolescent; Adult; Aged; Biomarkers, Tumor; Brain; Brain Neoplasms; Child; Child, Preschool; Chromat

1993
Polyamine metabolism in gliomas.
    Journal of neuro-oncology, 1996, Volume: 29, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Astrocytoma; Brain Neoplasms; Child; Child, Preschool; F

1996
Choice of vincristine or 6-mercaptopurine on the basis of polyamine level in tumor-bearing regions of the brain.
    Cancer letters, 1999, May-03, Volume: 139, Issue:1

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Chroma

1999
Chemotherapy for pancreatic cancer: a neuroimaging clinicopathologic correlation.
    Journal of neuroimaging : official journal of the American Society of Neuroimaging, 1999, Volume: 9, Issue:3

    Topics: Adenocarcinoma; Antineoplastic Agents; Brain; Brain Neoplasms; Demyelinating Diseases; Diagnosis, Di

1999
Effect of cations on the formation of DNA alkylation products in DNA reacted with 1-(2-Chloroethyl)-1-nitrosourea.
    Chemical research in toxicology, 1999, Volume: 12, Issue:10

    Topics: Alkylating Agents; Alkylation; Animals; Brain Neoplasms; Cations; Cattle; Chromatography, High Press

1999
Putrescine as a biochemical marker of malignant brain tumors.
    Cancer research, 1979, Volume: 39, Issue:12

    Topics: Astrocytoma; Brain Chemistry; Brain Neoplasms; Glioblastoma; Humans; Neoplasms, Nerve Tissue; Putres

1979
Kinetics and distribution of tritiated putrescine in the domestic cat.
    European journal of cancer, 1979, Volume: 15, Issue:11

    Topics: Animals; Astrocytoma; Brain Neoplasms; Cats; Dose-Response Relationship, Drug; Glioblastoma; Kinetic

1979
[Measurement of blood polyamines in patients with brain tumor--special reference to relationship between the blood levels of spermidine and spermine, and histological malignancy in patients with glioma (author's transl)].
    No to shinkei = Brain and nerve, 1977, Volume: 29, Issue:11

    Topics: Adenoma; Adolescent; Adult; Astrocytoma; Brain Neoplasms; Ependymoma; Glioma; Hemangiosarcoma; Human

1977
Depletion of intracellular putrescine and spermidine by alpha-difluromethylornithine does not inhibit proliferation of 9L rat brain tumor cells.
    Biochemical and biophysical research communications, 1979, Feb-28, Volume: 86, Issue:4

    Topics: Animals; Brain Neoplasms; Carboxy-Lyases; Cell Division; Depression, Chemical; Dose-Response Relatio

1979
Effect of methylglyoxal-bis (guanylhydrazone), an inhibitor of spermidine and spermine synthesis, on cell cycle traverse.
    European journal of cancer, 1977, Volume: 13, Issue:9

    Topics: Animals; Brain Neoplasms; Cell Cycle; Cells, Cultured; Guanidines; Mitoguazone; Putrescine; Rats; Sp

1977
[Determination of blood polyamines in patients with brain tumor -with special reference to relationship between varieties of tumors and concentrations of blood spermidine and spermine (author's transl)].
    No shinkei geka. Neurological surgery, 1976, Volume: 4, Issue:11

    Topics: Adult; Brain Neoplasms; Female; Glioma; Humans; Male; Meningioma; Middle Aged; Neurilemmoma; Pinealo

1976
Polyamines: a high correlation with cell replication.
    FEBS letters, 1975, Jan-15, Volume: 50, Issue:1

    Topics: Animals; Brain Neoplasms; Cell Division; Cell Line; Cells, Cultured; DNA, Neoplasm; Nitrosourea Comp

1975
More sensitive automated detection of polyamines in physiological fluids and tissue extracts with omicron-phthalaldehyde.
    Clinical chemistry, 1975, Volume: 21, Issue:12

    Topics: Aldehydes; Amniotic Fluid; Animals; Autoanalysis; Brain Neoplasms; Evaluation Studies as Topic; Fema

1975
The relationship of polyamines in cerebrospinal fluid to the presence of central nervous system tumors.
    Cancer research, 1976, Volume: 36, Issue:3

    Topics: Adenoma; Astrocytoma; Brain Neoplasms; Central Nervous System Diseases; Glioma; Humans; Medulloblast

1976
Effect of polyamine depletion on chromatin structure in U-87 MG human brain tumour cells.
    The Biochemical journal, 1992, Mar-15, Volume: 282 ( Pt 3)

    Topics: Brain Neoplasms; Cell Nucleus; Chromatin; Culture Media, Serum-Free; Deoxyribonuclease I; Eflornithi

1992
Effect on N1,N14-bis-(ethyl)-homospermine (BE-4-4-4) on the growth of U-251 MG and SF-188 human brain tumor cells.
    International journal of cancer, 1991, Jul-30, Volume: 48, Issue:6

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Line; Cell Survival; Humans; Kinetics; Polyamines; Putr

1991
Effect of N1,N14-bis(ethyl)homospermine on the growth of U-87 MG and SF-126 human brain tumor cells.
    Cancer research, 1990, Jun-01, Volume: 50, Issue:11

    Topics: Brain Neoplasms; Cell Division; Humans; Putrescine; Spermidine; Spermine; Tumor Cells, Cultured

1990
Red blood cell polyamines as a diagnostic indicator of glioma presence and recurrence.
    Journal of neuro-oncology, 1989, Volume: 7, Issue:1

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Child; Child, Preschool; Female; Glioma; Humans; Male; Mid

1989
Cerebrospinal fluid polyamines: biochemical markers of malignant childhood brain tumors.
    Annals of neurology, 1986, Volume: 19, Issue:4

    Topics: Adolescent; Astrocytoma; Brain Neoplasms; Child; Child, Preschool; Humans; Medulloblastoma; Neoplasm

1986
Putrescine metabolism in human brain tumors.
    Journal of neuro-oncology, 1986, Volume: 4, Issue:1

    Topics: Astrocytoma; Brain Neoplasms; Humans; In Vitro Techniques; Meningioma; Neurilemmoma; Putrescine; Spe

1986
Elevated levels of free putrescine and N1-acetylspermidine in cyst fluids of malignant brain tumours.
    Journal of neurology, neurosurgery, and psychiatry, 1986, Volume: 49, Issue:2

    Topics: Brain; Brain Neoplasms; Cysts; Humans; Putrescine; Spermidine; Spermine

1986
Increased polyamine concentrations in the cerebrospinal fluid of patients with brain tumors.
    International journal of cancer, 1974, Dec-15, Volume: 14, Issue:6

    Topics: Adenoma, Acidophil; Adenoma, Chromophobe; Adolescent; Adult; Aged; Astrocytoma; Brain Neoplasms; Cer

1974
Polyamine metabolism in tumor, spleen and liver of tumor-bearing rats.
    International journal of cancer, 1974, May-15, Volume: 13, Issue:5

    Topics: Animals; Body Weight; Brain Neoplasms; Carbon Radioisotopes; Carboxy-Lyases; Liver; Male; Neoplasm T

1974
An automated micromethod for the quantitative analysis of di- and polyamines utilizing a sensitive high pressure liquid chromatographic procedure.
    FEBS letters, 1974, Apr-15, Volume: 41, Issue:1

    Topics: Animals; Autoanalysis; Brain; Brain Chemistry; Brain Neoplasms; Cadaverine; Carbon Radioisotopes; Ch

1974
Urinary polyamines in cancer patients.
    Cancer research, 1971, Volume: 31, Issue:11

    Topics: Brain Neoplasms; Chemistry, Clinical; Daunorubicin; Female; Hodgkin Disease; Humans; Leukemia, Lymph

1971
Regulation of meningioma cell growth in vitro by polyamines.
    Journal of neuropathology and experimental neurology, 1971, Volume: 30, Issue:4

    Topics: Biopsy; Brain Neoplasms; Butylamines; Cell Count; Cells, Cultured; Culture Media; Culture Techniques

1971