spermine has been researched along with Aging in 67 studies
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Chlorophyll and electrical conductance had a inverse relationship throughout the experimental period, whereas, the chlorophyll content was directly related with polyamine levels in both stipule and pod wall during aging." | 3.71 | Changes in free polyamines and related enzymes during stipule and pod wall development in Pisum sativum. ( Bharati, G; Chattopadhyay, S; Lahiri, K, 2002) |
| " We examined the influence of regional distribution and aging on putrescine, spermidine, and spermine levels in autopsied human brain." | 3.69 | Polyamines in human brain: regional distribution and influence of aging. ( Ang, LC; Becker, L; Kish, SJ; Morrison, LD, 1995) |
| "Because spermine and spermidine have caused hypothermia in rodent experiments, we tested the hypothesis that these polyamines accumulate in some elderly convalescent patients and that this accumulation could predispose to lower body temperature." | 3.67 | Accumulation of polyamines and their weak association with lower body temperature in elderly convalescent patients. ( Bond, O; Drayer, DE; Orto, L; Reidenberg, MM; Restivo, KM, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 32 (47.76) | 18.7374 |
| 1990's | 18 (26.87) | 18.2507 |
| 2000's | 8 (11.94) | 29.6817 |
| 2010's | 6 (8.96) | 24.3611 |
| 2020's | 3 (4.48) | 2.80 |
| Authors | Studies |
|---|---|
| Uemura, T | 1 |
| Matsunaga, M | 1 |
| Yokota, Y | 1 |
| Takao, K | 2 |
| Furuchi, T | 1 |
| Fischer, M | 1 |
| Ruhnau, J | 1 |
| Schulze, J | 1 |
| Obst, D | 1 |
| Flöel, A | 1 |
| Vogelgesang, A | 1 |
| Leruez, S | 1 |
| Marill, A | 1 |
| Bresson, T | 1 |
| de Saint Martin, G | 1 |
| Buisset, A | 1 |
| Muller, J | 1 |
| Tessier, L | 1 |
| Gadras, C | 1 |
| Verny, C | 1 |
| Gohier, P | 1 |
| Amati-Bonneau, P | 1 |
| Lenaers, G | 1 |
| Bonneau, D | 1 |
| Simard, G | 1 |
| Milea, D | 1 |
| Procaccio, V | 1 |
| Reynier, P | 1 |
| Chao de la Barca, JM | 1 |
| Soda, K | 4 |
| Kano, Y | 3 |
| Chiba, F | 1 |
| Koizumi, K | 1 |
| Miyaki, Y | 1 |
| Enot, DP | 1 |
| Niso-Santano, M | 1 |
| Durand, S | 1 |
| Chery, A | 1 |
| Pietrocola, F | 1 |
| Vacchelli, E | 1 |
| Madeo, F | 1 |
| Galluzzi, L | 1 |
| Kroemer, G | 1 |
| Dobashi, Y | 1 |
| Tsujinaka, S | 1 |
| Konishi, F | 2 |
| Sakuragi, M | 1 |
| Lefor, A | 1 |
| Meng, K | 1 |
| Li, YH | 1 |
| Zhang, L | 1 |
| Li, P | 1 |
| Han, TZ | 1 |
| Cerrada-Gimenez, M | 1 |
| Pietilä, M | 1 |
| Loimas, S | 1 |
| Pirinen, E | 1 |
| Hyvönen, MT | 1 |
| Keinänen, TA | 1 |
| Jänne, J | 1 |
| Alhonen, L | 1 |
| Liu, P | 1 |
| Zhang, H | 1 |
| Devaraj, R | 1 |
| Ganesalingam, GS | 1 |
| Smith, PF | 1 |
| Schteingart, HF | 1 |
| Cigorraga, SB | 1 |
| Calandra, RS | 1 |
| Gonzalez-Calvar, SI | 1 |
| Chattopadhyay, S | 1 |
| Lahiri, K | 1 |
| Bharati, G | 1 |
| JAENNE, J | 1 |
| RAINA, A | 1 |
| SIIMES, M | 1 |
| Serkova, NJ | 1 |
| Gamito, EJ | 1 |
| Jones, RH | 1 |
| O'Donnell, C | 1 |
| Brown, JL | 1 |
| Green, S | 1 |
| Sullivan, H | 1 |
| Hedlund, T | 1 |
| Crawford, ED | 1 |
| Supakar, PC | 1 |
| Kanungo, MS | 4 |
| Seiler, N | 3 |
| Sarhan, S | 1 |
| Roth-Schechter, BF | 1 |
| Scalabrino, G | 1 |
| Ferioli, ME | 3 |
| Grillo, MA | 1 |
| Dianzani, U | 1 |
| Pezzali, DC | 1 |
| Mezzetti, G | 1 |
| Moruzzi, MS | 1 |
| Barbiroli, B | 1 |
| Rath, NC | 1 |
| Reddi, AH | 1 |
| Slotkin, TA | 1 |
| Weigel, SJ | 1 |
| Seidler, FJ | 1 |
| Whitmore, WL | 1 |
| Laitinen, SI | 1 |
| Laitinen, PH | 1 |
| Hietala, OA | 1 |
| Pajunen, AE | 1 |
| Piha, RS | 1 |
| Bose, R | 1 |
| Kaminska, AM | 1 |
| Stern, LZ | 1 |
| Russell, DH | 2 |
| Nabekura, J | 1 |
| Kawamoto, I | 1 |
| Horimoto, N | 1 |
| Ogawa, T | 1 |
| Morrison, LD | 1 |
| Becker, L | 1 |
| Ang, LC | 1 |
| Kish, SJ | 1 |
| Contestabile, A | 1 |
| Facchinetti, F | 1 |
| Ciani, E | 1 |
| Sparapani, M | 1 |
| Virgili, M | 1 |
| Buts, JP | 1 |
| De Keyser, N | 1 |
| Romain, N | 1 |
| Dandrifosse, G | 1 |
| Sokal, E | 1 |
| Nsengiyumva, T | 1 |
| Sessa, A | 1 |
| Tunici, P | 1 |
| Pinotti, O | 1 |
| Perin, A | 1 |
| Forget, PP | 2 |
| Degraeuwe, PL | 1 |
| Smeets, C | 1 |
| Deutz, NE | 1 |
| ter Steege, JC | 1 |
| Buurman, WA | 1 |
| Hilliard, AL | 1 |
| Ramesh, A | 1 |
| Zawia, NH | 1 |
| Rumbaugh, G | 2 |
| Vicini, S | 2 |
| Prybylowski, K | 1 |
| Wolfe, BB | 1 |
| Vivó, M | 1 |
| de Vera, N | 1 |
| Cortés, R | 1 |
| Mengod, G | 1 |
| Camón, L | 1 |
| Martínez, E | 1 |
| Galston, AW | 1 |
| Sawhney, RK | 1 |
| Clayton, DA | 1 |
| Mesches, MH | 1 |
| Alvarez, E | 1 |
| Bickford, PC | 1 |
| Browning, MD | 1 |
| Das, R | 1 |
| Symonds, GW | 2 |
| Brosnan, ME | 2 |
| Hall, DE | 1 |
| Symonds, DL | 1 |
| Macaione, S | 1 |
| Calatroni, A | 1 |
| Sturman, JA | 1 |
| Gaull, GE | 1 |
| Shaskan, EG | 1 |
| McAnulty, PA | 1 |
| Yusuf, HK | 1 |
| Dickerson, JW | 1 |
| Hey, EN | 1 |
| Waterlow, JC | 1 |
| Ball, WJ | 1 |
| Balis, ME | 1 |
| Lamberty, U | 1 |
| Comolli, R | 2 |
| Suorsa, A | 1 |
| Hietala, O | 1 |
| Pajunen, A | 1 |
| Eguchi, K | 1 |
| Yonezawa, M | 1 |
| Ohmoto, H | 1 |
| Mitsui, Y | 1 |
| Hiramatsu, Y | 1 |
| Pedersen, SB | 1 |
| Børglum, JD | 1 |
| Eriksen, EF | 1 |
| Richelsen, B | 1 |
| Poston, GJ | 1 |
| Saydjari, R | 1 |
| Lawrence, J | 1 |
| Alexander, RW | 1 |
| Townsend, CM | 1 |
| Thompson, JC | 1 |
| Thakur, MK | 3 |
| Prasad, S | 3 |
| Zaalishvili, TM | 1 |
| Dzhaparidze, NSh | 1 |
| Sabelashvili, DSh | 1 |
| Michilashvili, RD | 1 |
| Pöyhönen, MJ | 1 |
| Uusitalo, UM | 1 |
| Kari, A | 1 |
| Takala, JA | 1 |
| Alakuijala, LA | 1 |
| Eloranta, TO | 1 |
| Jensen, JR | 1 |
| Lynch, G | 1 |
| Baudry, M | 1 |
| Cascales, C | 1 |
| Boscá, L | 1 |
| Martin, A | 1 |
| Brindley, DN | 1 |
| Cascales, M | 1 |
| Orlandini, G | 1 |
| Bernasconi, S | 1 |
| Zannino, L | 1 |
| Bacciottini, F | 1 |
| Frezza, E | 1 |
| Reali, N | 1 |
| Casti, A | 1 |
| Bolkenius, FN | 1 |
| Ekker, M | 1 |
| Sourkes, TL | 1 |
| Restivo, KM | 1 |
| Drayer, DE | 1 |
| Orto, L | 1 |
| Bond, O | 1 |
| Reidenberg, MM | 1 |
| Das, BR | 1 |
| Nishida, Y | 1 |
| Miyamoto, T | 1 |
| Lombardini, JP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Polyamine-enriched Dietary Supplementation on Cognitive Function in Healthy Older Adults With Subjective Cognitive Decline[NCT02755246] | Phase 2 | 30 participants (Actual) | Interventional | 2016-04-30 | Completed | ||
| Effect of Polyamine-enriched Dietary Supplementation on Cognitive Function and Biomarkers in Elderly Individuals With Subjective Cognitive Decline[NCT03094546] | Phase 2 | 100 participants (Actual) | Interventional | 2017-01-31 | Completed | ||
| TArgeting Type 1 Diabetes Using POLyamines (TADPOL): A Randomized, Double-Masked, Placebo-Controlled Phase 2 Study to Evaluate the Efficacy and Safety of Difluoromethylornithine (DFMO) to Preserve Insulin Production in Type 1 Diabetes[NCT05594563] | Phase 2 | 70 participants (Anticipated) | Interventional | 2023-03-14 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for spermine and Aging
| Article | Year |
|---|---|
Spermine and gene methylation: a mechanism of lifespan extension induced by polyamine-rich diet.
Topics: Aging; Animals; Diet; DNA Methylation; Humans; Longevity; Polyamines; Spermine | 2020 |
Polyamines in mammalian ageing: an oncological problem, too? A review.
Topics: Adenosylmethionine Decarboxylase; Aging; Animals; Humans; Male; Neoplasms; Ornithine Decarboxylase; | 1984 |
Polyamines in plant physiology.
Topics: Aging; Carboxy-Lyases; Morphogenesis; Ornithine Decarboxylase; Plant Development; Plant Physiologica | 1990 |
64 other studies available for spermine and Aging
| Article | Year |
|---|---|
Inhibition of Polyamine Catabolism Reduces Cellular Senescence.
Topics: Aging; Cellular Senescence; Humans; Polyamines; Spermidine; Spermine | 2023 |
Spermine and spermidine modulate T-cell function in older adults with and without cognitive decline ex vivo.
Topics: Aged; Aged, 80 and over; Aging; Autophagy; Case-Control Studies; Cognitive Dysfunction; Cytokines; D | 2020 |
A Metabolomics Profiling of Glaucoma Points to Mitochondrial Dysfunction, Senescence, and Polyamines Deficiency.
Topics: Aged; Aging; Eye Proteins; Female; Glaucoma, Open-Angle; Humans; Male; Mass Spectrometry; Metabolome | 2018 |
Increased polyamine intake inhibits age-associated alteration in global DNA methylation and 1,2-dimethylhydrazine-induced tumorigenesis.
Topics: Aging; Animals; Cell Line; Colonic Neoplasms; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; | 2013 |
Metabolomic analyses reveal that anti-aging metabolites are depleted by palmitate but increased by oleate in vivo.
Topics: Aging; Amino Acids; Animals; Autophagy; Female; Liver; Mass Spectrometry; Metabolomics; Mice; Mice, | 2015 |
Polyamine-rich food decreases age-associated pathology and mortality in aged mice.
Topics: Aging; Animals; Diet; Longevity; Male; Mice; Polyamines; Spermidine; Spermine | 2009 |
Polyamine-rich food decreases age-associated pathology and mortality in aged mice.
Topics: Aging; Animals; Diet; Longevity; Male; Mice; Polyamines; Spermidine; Spermine | 2009 |
Polyamine-rich food decreases age-associated pathology and mortality in aged mice.
Topics: Aging; Animals; Diet; Longevity; Male; Mice; Polyamines; Spermidine; Spermine | 2009 |
Polyamine-rich food decreases age-associated pathology and mortality in aged mice.
Topics: Aging; Animals; Diet; Longevity; Male; Mice; Polyamines; Spermidine; Spermine | 2009 |
Long-term oral polyamine intake increases blood polyamine concentrations.
Topics: Adult; Aged; Aging; Animals; Diet; Dose-Response Relationship, Drug; Glycine max; Humans; Male; Mice | 2009 |
Long-term oral polyamine intake increases blood polyamine concentrations.
Topics: Adult; Aged; Aging; Animals; Diet; Dose-Response Relationship, Drug; Glycine max; Humans; Male; Mice | 2009 |
Long-term oral polyamine intake increases blood polyamine concentrations.
Topics: Adult; Aged; Aging; Animals; Diet; Dose-Response Relationship, Drug; Glycine max; Humans; Male; Mice | 2009 |
Long-term oral polyamine intake increases blood polyamine concentrations.
Topics: Adult; Aged; Aging; Animals; Diet; Dose-Response Relationship, Drug; Glycine max; Humans; Male; Mice | 2009 |
Long-term oral polyamine intake increases blood polyamine concentrations.
Topics: Adult; Aged; Aging; Animals; Diet; Dose-Response Relationship, Drug; Glycine max; Humans; Male; Mice | 2009 |
Long-term oral polyamine intake increases blood polyamine concentrations.
Topics: Adult; Aged; Aging; Animals; Diet; Dose-Response Relationship, Drug; Glycine max; Humans; Male; Mice | 2009 |
Long-term oral polyamine intake increases blood polyamine concentrations.
Topics: Adult; Aged; Aging; Animals; Diet; Dose-Response Relationship, Drug; Glycine max; Humans; Male; Mice | 2009 |
Long-term oral polyamine intake increases blood polyamine concentrations.
Topics: Adult; Aged; Aging; Animals; Diet; Dose-Response Relationship, Drug; Glycine max; Humans; Male; Mice | 2009 |
Long-term oral polyamine intake increases blood polyamine concentrations.
Topics: Adult; Aged; Aging; Animals; Diet; Dose-Response Relationship, Drug; Glycine max; Humans; Male; Mice | 2009 |
Ca2+-permeable AMPA receptors mediate induction of test pulse depression of naive synapses in rat visual cortical slices at early postnatal stage.
Topics: 2-Amino-5-phosphonovalerate; Adamantane; Aging; Animals; Electric Stimulation; Evoked Potentials; Ex | 2010 |
Continuous oxidative stress due to activation of polyamine catabolism accelerates aging and protects against hepatotoxic insults.
Topics: Acetyltransferases; Aging; Animals; Carbon Tetrachloride; Liver; Male; Mice; Mice, Transgenic; Oxida | 2011 |
A multivariate analysis of the effects of aging on glutamate, GABA and arginine metabolites in the rat vestibular nucleus.
Topics: Aging; Animals; Arginine; Cerebellum; Cluster Analysis; gamma-Aminobutyric Acid; Glutamic Acid; Male | 2010 |
Modulation by polyamines of gamma-glutamyl transpeptidase activity and lactate production in cultured Sertoli cells from immature and adult regressed golden hamster.
Topics: Aging; Animals; Cells, Cultured; Cricetinae; Follicle Stimulating Hormone; gamma-Glutamyltransferase | 2002 |
Changes in free polyamines and related enzymes during stipule and pod wall development in Pisum sativum.
Topics: Aging; Amine Oxidase (Copper-Containing); Carboxy-Lyases; Chlorophyll; DNA, Plant; Electric Conducti | 2002 |
SPERMIDINE AND SPERMINE IN RAT TISSUES AT DIFFERENT AGES.
Topics: Adipose Tissue; Aging; Amines; Animals; Animals, Newborn; Brain; Coloring Agents; Electrophoresis; F | 1964 |
The metabolites citrate, myo-inositol, and spermine are potential age-independent markers of prostate cancer in human expressed prostatic secretions.
Topics: Adult; Aged; Aging; Area Under Curve; Biomarkers, Tumor; Body Fluids; Citric Acid; Humans; Inositol; | 2008 |
Chromatin function in developing brain: acetylation of chromosomal proteins and RNA synthesis.
Topics: Acetylation; Aging; Animals; Cerebral Cortex; Chromatin; Chromosomal Proteins, Non-Histone; Histones | 1981 |
Developmental changes of the GABA and polyamine systems in isolated neurons in cell culture.
Topics: Aging; Amino Acids; Animals; Cerebral Cortex; Chick Embryo; DNA; gamma-Aminobutyric Acid; Putrescine | 1981 |
Acetylation of polyamines in chicken brain and retina.
Topics: Acetylation; Acetyltransferases; Aging; Alkaline Phosphatase; Animals; Brain; Chick Embryo; Chickens | 1984 |
Changes of duodenal spermine-binding activity caused by vitamin D deficiency.
Topics: Aging; Animals; Calcitriol; Chickens; Duodenum; Spermine; Vitamin D Deficiency | 1983 |
Changes in polyamines, RNA synthesis, and cell proliferation during matrix-induced cartilage, bone, and bone marrow development.
Topics: Adenosylmethionine Decarboxylase; Aging; Animals; Bone and Bones; Bone Marrow; Bone Transplantation; | 1981 |
Toxic effects of maternal methadone administration on cardiac development in the neonatal rat: potential participation of altered polyamine levels in growth impairment.
Topics: Aging; Animals; Animals, Newborn; Female; Heart; Methadone; Myocardium; Ornithine Decarboxylase; Pol | 1982 |
Developmental changes in mouse brain polyamine metabolism.
Topics: Adenosylmethionine Decarboxylase; Aging; Animals; Brain; Carboxy-Lyases; Kinetics; Mice; Mice, Inbre | 1982 |
Polyamines modulate phosphorylation and acetylation of non-histone chromosomal proteins of the cerebral cortex of rats of various ages.
Topics: Acetylation; Aging; Animals; Cerebral Cortex; Chromosomal Proteins, Non-Histone; DNA; Histones; In V | 1982 |
Polyamine accumulation in normal and denervated neonatal muscle.
Topics: Aging; Animals; Animals, Newborn; Female; Male; Muscle Denervation; Muscles; Polyamines; Putrescine; | 1981 |
Developmental change of the potentiation of NMDA response by spermine.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Drug Synergism; Electrophy | 1995 |
Polyamines in human brain: regional distribution and influence of aging.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Animals; Brain; Child; Child, Preschool; Humans; | 1995 |
Chronic neonatal blockade of NMDA receptor does not affect developmental polyamine metabolism but results in altered response to the excitotoxic induction of ornithine decarboxylase.
Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Animals, Newborn; Brain; Cerebellum; Cerebral Cortex; E | 1994 |
Response of rat immature enterocytes to insulin: regulation by receptor binding and endoluminal polyamine uptake.
Topics: Adrenalectomy; Aging; Animals; Animals, Newborn; Antibodies, Monoclonal; Eflornithine; Hydrolases; I | 1994 |
Aging and polyamine acetylation in rat kidney.
Topics: Acetylation; Acetyltransferases; Aging; Animals; Histones; Kidney; Male; Oxidoreductases Acting on C | 1996 |
Fasting gastric fluid and fecal polyamine concentrations in premature infants.
Topics: Aging; Cadaverine; Chromatography, High Pressure Liquid; Fasting; Feces; Gastric Juice; Gestational | 1997 |
Spermine induces maturation of the immature intestinal immune system in neonatal mice.
Topics: Aging; Animals; Animals, Newborn; beta-Galactosidase; CD4 Antigens; CD5 Antigens; Epithelial Cells; | 1997 |
Regional variations in spermine levels in the developing rat brain following exposure to lead.
Topics: Aging; Animals; Animals, Newborn; Brain; Chromatography, High Pressure Liquid; Lead; Rats; Rats, Lon | 1999 |
Distinct synaptic and extrasynaptic NMDA receptors in developing cerebellar granule neurons.
Topics: Aging; Animals; Animals, Newborn; Cerebellum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists | 1999 |
Increased exon 5 expression alters extrasynaptic NMDA receptors in cerebellar neurons.
Topics: Aging; Alternative Splicing; Animals; Animals, Newborn; Cell Membrane; Cerebellum; Cerebral Cortex; | 2000 |
Polyamines in the basal ganglia of human brain. Influence of aging and degenerative movement disorders.
Topics: Aged; Aged, 80 and over; Aging; Analysis of Variance; Basal Ganglia; Biogenic Polyamines; Female; Hu | 2001 |
A hippocampal NR2B deficit can mimic age-related changes in long-term potentiation and spatial learning in the Fischer 344 rat.
Topics: Action Potentials; Aging; Animals; Behavior, Animal; Blotting, Western; Calcium Channel Blockers; Ca | 2002 |
Effects of polyamines on in vitro phosphorylation and acetylation of histones of the cerebral cortex of rats of various ages.
Topics: Acetylation; Aging; Animals; Cerebral Cortex; Female; Histones; Phosphorylation; Rats; Spermidine; S | 1979 |
Effect of age of rat on polyamine content of liver nuclei [proceedings].
Topics: Aging; Animals; Cell Nucleus; Liver; Polyamines; Rats; Spermidine; Spermine | 1977 |
Analysis of spermidine and spermine in rat liver. Effect of hypophysectomy on polyamine concentrations.
Topics: Aging; Animals; Chromatography, Ion Exchange; Hypophysectomy; Liver; Male; Rats; Spermidine; Spermin | 1978 |
Polyamines and ornithine decarboxylase activity in the developing rat retina.
Topics: Aging; Animals; Animals, Newborn; Carboxy-Lyases; Eye Proteins; Female; Male; Ornithine Decarboxylas | 1978 |
Polyamine metabolism in the brain and liver of the developing monkey.
Topics: Adenosylmethionine Decarboxylase; Aging; Animals; Brain; Female; Haplorhini; Liver; Macaca mulatta; | 1975 |
Brain regional spermidine and spermine levels in relation to RNA and DNA in aging rat brain.
Topics: Aging; Animals; Brain; Brain Chemistry; Cerebral Cortex; Corpus Striatum; DNA; Hippocampus; Hypothal | 1977 |
Polyamines of the human brain during normal fetal and postnatal growth and during postnatal malnutrition.
Topics: Aging; Brain; Brain Stem; Cerebellum; Child, Preschool; Female; Fetus; Gestational Age; Humans; Infa | 1977 |
Changes in ornithine decarboxylase activity in rat intestines during aging.
Topics: Aging; Animals; Brain; Carboxy-Lyases; Female; Intestines; Kinetics; Liver; Male; Nucleotides; Ornit | 1976 |
Interrelations between polyamines and nucleic acids: changes of polyamine and nucleic acid concentrations in the developing rat brain.
Topics: Aging; Animals; Brain; DNA; Nerve Tissue Proteins; Polyamines; Putrescine; Rats; RNA; Spermidine; Sp | 1975 |
Changes of liver and kidney polyamine levels during aging.
Topics: Aging; Animals; Kidney; Liver; Male; Rats; Spermidine; Spermine | 1975 |
Developmental expression of ornithine and S-adenosylmethionine decarboxylases in mouse brain.
Topics: Adenosylmethionine Decarboxylase; Aging; Animals; Brain; DNA Probes; Gene Expression Regulation, Enz | 1992 |
Development changes of polyamine biosynthesis in rat liver.
Topics: Acetyltransferases; Adenosylmethionine Decarboxylase; Aging; Animals; Animals, Newborn; Gestational | 1992 |
Nuclear estradiol binding in rat adipocytes. Regional variations and regulatory influences of hormones.
Topics: Adipose Tissue; Aging; Animals; Bucladesine; Cell Nucleus; Estradiol; Insulin; Isoproterenol; Kineti | 1991 |
The effect of age on small bowel adaptation and growth after proximal enterectomy.
Topics: Adaptation, Physiological; Aging; Animals; Body Weight; DNA; Intestinal Mucosa; Intestine, Small; Ma | 1990 |
Analysis of age-associated alteration in the synthesis of HMG nonhistone proteins of the rat liver.
Topics: Aging; Animals; Benzamides; Butyrates; Butyric Acid; Dexamethasone; Electrophoresis, Polyacrylamide | 1991 |
[The effect of Cu2+, Zn2+ cations and biogenic amines on the nuclear poly(ADP-ribose) polymerase activity in the rat brain].
Topics: Aging; Animals; Biogenic Polyamines; Brain; Cations, Divalent; Cell Nucleus; Copper; Enzyme Activati | 1990 |
ADP-ribosylation of HMG proteins and its modulation by different effectors in the liver of aging rats.
Topics: Adenosine Diphosphate Ribose; Aging; Animals; Benzamides; Butyrates; Butyric Acid; Dexamethasone; Hi | 1990 |
Urinary excretion of polyamines: importance of circadian rhythm, age, sex, menstrual cycle, weight, and creatinine excretion.
Topics: Adult; Aging; Body Weight; Chromatography; Circadian Rhythm; Creatinine; Female; Humans; Male; Menst | 1990 |
Allosteric activation of brain mitochondrial Ca2+ uptake by spermine and by Ca2+: developmental changes.
Topics: Aging; Allosteric Regulation; Animals; Brain; Calcium; Hippocampus; Kinetics; Mitochondria; Rats; Sp | 1989 |
Age-related changes in the translocation of phosphatidate phosphohydrolase from the cytosol to microsomal membranes in rat liver.
Topics: Aging; Animals; Chlorpromazine; Cytosol; Intracellular Membranes; Kinetics; Liver; Male; Microsomes, | 1988 |
Age-specific methylation of high-mobility-group proteins of the rat liver and its modulation by spermine and sodium butyrate.
Topics: Aging; Animals; Butyrates; Butyric Acid; Chromatin; High Mobility Group Proteins; Liver; Male; Methi | 1989 |
Changes of polyamine concentrations in infants during the first six months of life.
Topics: Aging; Diet; Female; Humans; Infant; Infant, Newborn; Male; Polyamines; Spermidine; Spermine | 1987 |
Developmental aspects of polyamine interconversion in rat brain.
Topics: Aging; Animals; Blood-Brain Barrier; Brain; Female; Male; Oxidoreductases Acting on CH-NH Group Dono | 1986 |
Developmental pattern of ornithine decarboxylase activity, S-adenosylmethionine decarboxylase, and polyamines of rat adrenal glands.
Topics: Adenosylmethionine Decarboxylase; Adrenal Glands; Aging; Animals; Carboxy-Lyases; Cold Temperature; | 1987 |
Accumulation of polyamines and their weak association with lower body temperature in elderly convalescent patients.
Topics: Adult; Aged; Aged, 80 and over; Aging; Body Temperature Regulation; Chromatography, High Pressure Li | 1987 |
In vitro ADP-ribosylation of chromosomal proteins of the brain of developing rats.
Topics: Adenosine Diphosphate Ribose; Aging; Animals; Benzamides; Brain; Chromosomal Proteins, Non-Histone; | 1986 |
Fetal calf serum-mediated toxicity of human polyamines to lymphocytes.
Topics: Aging; Cell Survival; Humans; In Vitro Techniques; Lymphocytes; Mitogens; Polyamines; Putrescine; Sp | 1986 |
Polyamine effects on 14C-leucine transfer to microsomal protein in a rat liver cell free system during ageing.
Topics: Aging; Animals; Carbon Radioisotopes; Cell-Free System; Centrifugation; Cytoplasm; Isotope Labeling; | 1973 |
Polyamines. (1) Enhanced s-adenosyl-L-methionine decarboxylase in rapid growth systems, and (2) the relationships between polyamine concentration and RNA accumulation.
Topics: Aging; Amines; Animals; Carbon Isotopes; Carboxy-Lyases; Chemical Phenomena; Chemistry; Chick Embryo | 1971 |