Page last updated: 2024-10-20

spermine and Aging

spermine has been researched along with Aging in 67 studies

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
" Chlorophyll and electrical conductance had a inverse relationship throughout the experimental period, whereas, the chlorophyll content was directly related with polyamine levels in both stipule and pod wall during aging."3.71Changes in free polyamines and related enzymes during stipule and pod wall development in Pisum sativum. ( Bharati, G; Chattopadhyay, S; Lahiri, K, 2002)
" We examined the influence of regional distribution and aging on putrescine, spermidine, and spermine levels in autopsied human brain."3.69Polyamines in human brain: regional distribution and influence of aging. ( Ang, LC; Becker, L; Kish, SJ; Morrison, LD, 1995)
"Because spermine and spermidine have caused hypothermia in rodent experiments, we tested the hypothesis that these polyamines accumulate in some elderly convalescent patients and that this accumulation could predispose to lower body temperature."3.67Accumulation of polyamines and their weak association with lower body temperature in elderly convalescent patients. ( Bond, O; Drayer, DE; Orto, L; Reidenberg, MM; Restivo, KM, 1987)

Research

Studies (67)

TimeframeStudies, this research(%)All Research%
pre-199032 (47.76)18.7374
1990's18 (26.87)18.2507
2000's8 (11.94)29.6817
2010's6 (8.96)24.3611
2020's3 (4.48)2.80

Authors

AuthorsStudies
Uemura, T1
Matsunaga, M1
Yokota, Y1
Takao, K2
Furuchi, T1
Fischer, M1
Ruhnau, J1
Schulze, J1
Obst, D1
Flöel, A1
Vogelgesang, A1
Leruez, S1
Marill, A1
Bresson, T1
de Saint Martin, G1
Buisset, A1
Muller, J1
Tessier, L1
Gadras, C1
Verny, C1
Gohier, P1
Amati-Bonneau, P1
Lenaers, G1
Bonneau, D1
Simard, G1
Milea, D1
Procaccio, V1
Reynier, P1
Chao de la Barca, JM1
Soda, K4
Kano, Y3
Chiba, F1
Koizumi, K1
Miyaki, Y1
Enot, DP1
Niso-Santano, M1
Durand, S1
Chery, A1
Pietrocola, F1
Vacchelli, E1
Madeo, F1
Galluzzi, L1
Kroemer, G1
Dobashi, Y1
Tsujinaka, S1
Konishi, F2
Sakuragi, M1
Lefor, A1
Meng, K1
Li, YH1
Zhang, L1
Li, P1
Han, TZ1
Cerrada-Gimenez, M1
Pietilä, M1
Loimas, S1
Pirinen, E1
Hyvönen, MT1
Keinänen, TA1
Jänne, J1
Alhonen, L1
Liu, P1
Zhang, H1
Devaraj, R1
Ganesalingam, GS1
Smith, PF1
Schteingart, HF1
Cigorraga, SB1
Calandra, RS1
Gonzalez-Calvar, SI1
Chattopadhyay, S1
Lahiri, K1
Bharati, G1
JAENNE, J1
RAINA, A1
SIIMES, M1
Serkova, NJ1
Gamito, EJ1
Jones, RH1
O'Donnell, C1
Brown, JL1
Green, S1
Sullivan, H1
Hedlund, T1
Crawford, ED1
Supakar, PC1
Kanungo, MS4
Seiler, N3
Sarhan, S1
Roth-Schechter, BF1
Scalabrino, G1
Ferioli, ME3
Grillo, MA1
Dianzani, U1
Pezzali, DC1
Mezzetti, G1
Moruzzi, MS1
Barbiroli, B1
Rath, NC1
Reddi, AH1
Slotkin, TA1
Weigel, SJ1
Seidler, FJ1
Whitmore, WL1
Laitinen, SI1
Laitinen, PH1
Hietala, OA1
Pajunen, AE1
Piha, RS1
Bose, R1
Kaminska, AM1
Stern, LZ1
Russell, DH2
Nabekura, J1
Kawamoto, I1
Horimoto, N1
Ogawa, T1
Morrison, LD1
Becker, L1
Ang, LC1
Kish, SJ1
Contestabile, A1
Facchinetti, F1
Ciani, E1
Sparapani, M1
Virgili, M1
Buts, JP1
De Keyser, N1
Romain, N1
Dandrifosse, G1
Sokal, E1
Nsengiyumva, T1
Sessa, A1
Tunici, P1
Pinotti, O1
Perin, A1
Forget, PP2
Degraeuwe, PL1
Smeets, C1
Deutz, NE1
ter Steege, JC1
Buurman, WA1
Hilliard, AL1
Ramesh, A1
Zawia, NH1
Rumbaugh, G2
Vicini, S2
Prybylowski, K1
Wolfe, BB1
Vivó, M1
de Vera, N1
Cortés, R1
Mengod, G1
Camón, L1
Martínez, E1
Galston, AW1
Sawhney, RK1
Clayton, DA1
Mesches, MH1
Alvarez, E1
Bickford, PC1
Browning, MD1
Das, R1
Symonds, GW2
Brosnan, ME2
Hall, DE1
Symonds, DL1
Macaione, S1
Calatroni, A1
Sturman, JA1
Gaull, GE1
Shaskan, EG1
McAnulty, PA1
Yusuf, HK1
Dickerson, JW1
Hey, EN1
Waterlow, JC1
Ball, WJ1
Balis, ME1
Lamberty, U1
Comolli, R2
Suorsa, A1
Hietala, O1
Pajunen, A1
Eguchi, K1
Yonezawa, M1
Ohmoto, H1
Mitsui, Y1
Hiramatsu, Y1
Pedersen, SB1
Børglum, JD1
Eriksen, EF1
Richelsen, B1
Poston, GJ1
Saydjari, R1
Lawrence, J1
Alexander, RW1
Townsend, CM1
Thompson, JC1
Thakur, MK3
Prasad, S3
Zaalishvili, TM1
Dzhaparidze, NSh1
Sabelashvili, DSh1
Michilashvili, RD1
Pöyhönen, MJ1
Uusitalo, UM1
Kari, A1
Takala, JA1
Alakuijala, LA1
Eloranta, TO1
Jensen, JR1
Lynch, G1
Baudry, M1
Cascales, C1
Boscá, L1
Martin, A1
Brindley, DN1
Cascales, M1
Orlandini, G1
Bernasconi, S1
Zannino, L1
Bacciottini, F1
Frezza, E1
Reali, N1
Casti, A1
Bolkenius, FN1
Ekker, M1
Sourkes, TL1
Restivo, KM1
Drayer, DE1
Orto, L1
Bond, O1
Reidenberg, MM1
Das, BR1
Nishida, Y1
Miyamoto, T1
Lombardini, JP1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Polyamine-enriched Dietary Supplementation on Cognitive Function in Healthy Older Adults With Subjective Cognitive Decline[NCT02755246]Phase 230 participants (Actual)Interventional2016-04-30Completed
Effect of Polyamine-enriched Dietary Supplementation on Cognitive Function and Biomarkers in Elderly Individuals With Subjective Cognitive Decline[NCT03094546]Phase 2100 participants (Actual)Interventional2017-01-31Completed
TArgeting Type 1 Diabetes Using POLyamines (TADPOL): A Randomized, Double-Masked, Placebo-Controlled Phase 2 Study to Evaluate the Efficacy and Safety of Difluoromethylornithine (DFMO) to Preserve Insulin Production in Type 1 Diabetes[NCT05594563]Phase 270 participants (Anticipated)Interventional2023-03-14Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for spermine and Aging

ArticleYear
Spermine and gene methylation: a mechanism of lifespan extension induced by polyamine-rich diet.
    Amino acids, 2020, Volume: 52, Issue:2

    Topics: Aging; Animals; Diet; DNA Methylation; Humans; Longevity; Polyamines; Spermine

2020
Polyamines in mammalian ageing: an oncological problem, too? A review.
    Mechanisms of ageing and development, 1984, Volume: 26, Issue:2-3

    Topics: Adenosylmethionine Decarboxylase; Aging; Animals; Humans; Male; Neoplasms; Ornithine Decarboxylase;

1984
Polyamines in plant physiology.
    Plant physiology, 1990, Volume: 94, Issue:2

    Topics: Aging; Carboxy-Lyases; Morphogenesis; Ornithine Decarboxylase; Plant Development; Plant Physiologica

1990

Other Studies

64 other studies available for spermine and Aging

ArticleYear
Inhibition of Polyamine Catabolism Reduces Cellular Senescence.
    International journal of molecular sciences, 2023, Aug-29, Volume: 24, Issue:17

    Topics: Aging; Cellular Senescence; Humans; Polyamines; Spermidine; Spermine

2023
Spermine and spermidine modulate T-cell function in older adults with and without cognitive decline ex vivo.
    Aging, 2020, 06-30, Volume: 12, Issue:13

    Topics: Aged; Aged, 80 and over; Aging; Autophagy; Case-Control Studies; Cognitive Dysfunction; Cytokines; D

2020
A Metabolomics Profiling of Glaucoma Points to Mitochondrial Dysfunction, Senescence, and Polyamines Deficiency.
    Investigative ophthalmology & visual science, 2018, 09-04, Volume: 59, Issue:11

    Topics: Aged; Aging; Eye Proteins; Female; Glaucoma, Open-Angle; Humans; Male; Mass Spectrometry; Metabolome

2018
Increased polyamine intake inhibits age-associated alteration in global DNA methylation and 1,2-dimethylhydrazine-induced tumorigenesis.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Aging; Animals; Cell Line; Colonic Neoplasms; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation;

2013
Metabolomic analyses reveal that anti-aging metabolites are depleted by palmitate but increased by oleate in vivo.
    Cell cycle (Georgetown, Tex.), 2015, Aug-03, Volume: 14, Issue:15

    Topics: Aging; Amino Acids; Animals; Autophagy; Female; Liver; Mass Spectrometry; Metabolomics; Mice; Mice,

2015
Polyamine-rich food decreases age-associated pathology and mortality in aged mice.
    Experimental gerontology, 2009, Volume: 44, Issue:11

    Topics: Aging; Animals; Diet; Longevity; Male; Mice; Polyamines; Spermidine; Spermine

2009
Polyamine-rich food decreases age-associated pathology and mortality in aged mice.
    Experimental gerontology, 2009, Volume: 44, Issue:11

    Topics: Aging; Animals; Diet; Longevity; Male; Mice; Polyamines; Spermidine; Spermine

2009
Polyamine-rich food decreases age-associated pathology and mortality in aged mice.
    Experimental gerontology, 2009, Volume: 44, Issue:11

    Topics: Aging; Animals; Diet; Longevity; Male; Mice; Polyamines; Spermidine; Spermine

2009
Polyamine-rich food decreases age-associated pathology and mortality in aged mice.
    Experimental gerontology, 2009, Volume: 44, Issue:11

    Topics: Aging; Animals; Diet; Longevity; Male; Mice; Polyamines; Spermidine; Spermine

2009
Long-term oral polyamine intake increases blood polyamine concentrations.
    Journal of nutritional science and vitaminology, 2009, Volume: 55, Issue:4

    Topics: Adult; Aged; Aging; Animals; Diet; Dose-Response Relationship, Drug; Glycine max; Humans; Male; Mice

2009
Long-term oral polyamine intake increases blood polyamine concentrations.
    Journal of nutritional science and vitaminology, 2009, Volume: 55, Issue:4

    Topics: Adult; Aged; Aging; Animals; Diet; Dose-Response Relationship, Drug; Glycine max; Humans; Male; Mice

2009
Long-term oral polyamine intake increases blood polyamine concentrations.
    Journal of nutritional science and vitaminology, 2009, Volume: 55, Issue:4

    Topics: Adult; Aged; Aging; Animals; Diet; Dose-Response Relationship, Drug; Glycine max; Humans; Male; Mice

2009
Long-term oral polyamine intake increases blood polyamine concentrations.
    Journal of nutritional science and vitaminology, 2009, Volume: 55, Issue:4

    Topics: Adult; Aged; Aging; Animals; Diet; Dose-Response Relationship, Drug; Glycine max; Humans; Male; Mice

2009
Long-term oral polyamine intake increases blood polyamine concentrations.
    Journal of nutritional science and vitaminology, 2009, Volume: 55, Issue:4

    Topics: Adult; Aged; Aging; Animals; Diet; Dose-Response Relationship, Drug; Glycine max; Humans; Male; Mice

2009
Long-term oral polyamine intake increases blood polyamine concentrations.
    Journal of nutritional science and vitaminology, 2009, Volume: 55, Issue:4

    Topics: Adult; Aged; Aging; Animals; Diet; Dose-Response Relationship, Drug; Glycine max; Humans; Male; Mice

2009
Long-term oral polyamine intake increases blood polyamine concentrations.
    Journal of nutritional science and vitaminology, 2009, Volume: 55, Issue:4

    Topics: Adult; Aged; Aging; Animals; Diet; Dose-Response Relationship, Drug; Glycine max; Humans; Male; Mice

2009
Long-term oral polyamine intake increases blood polyamine concentrations.
    Journal of nutritional science and vitaminology, 2009, Volume: 55, Issue:4

    Topics: Adult; Aged; Aging; Animals; Diet; Dose-Response Relationship, Drug; Glycine max; Humans; Male; Mice

2009
Long-term oral polyamine intake increases blood polyamine concentrations.
    Journal of nutritional science and vitaminology, 2009, Volume: 55, Issue:4

    Topics: Adult; Aged; Aging; Animals; Diet; Dose-Response Relationship, Drug; Glycine max; Humans; Male; Mice

2009
Ca2+-permeable AMPA receptors mediate induction of test pulse depression of naive synapses in rat visual cortical slices at early postnatal stage.
    Neuroscience, 2010, Feb-03, Volume: 165, Issue:3

    Topics: 2-Amino-5-phosphonovalerate; Adamantane; Aging; Animals; Electric Stimulation; Evoked Potentials; Ex

2010
Continuous oxidative stress due to activation of polyamine catabolism accelerates aging and protects against hepatotoxic insults.
    Transgenic research, 2011, Volume: 20, Issue:2

    Topics: Acetyltransferases; Aging; Animals; Carbon Tetrachloride; Liver; Male; Mice; Mice, Transgenic; Oxida

2011
A multivariate analysis of the effects of aging on glutamate, GABA and arginine metabolites in the rat vestibular nucleus.
    Hearing research, 2010, Oct-01, Volume: 269, Issue:1-2

    Topics: Aging; Animals; Arginine; Cerebellum; Cluster Analysis; gamma-Aminobutyric Acid; Glutamic Acid; Male

2010
Modulation by polyamines of gamma-glutamyl transpeptidase activity and lactate production in cultured Sertoli cells from immature and adult regressed golden hamster.
    Endocrine research, 2002, Volume: 28, Issue:3

    Topics: Aging; Animals; Cells, Cultured; Cricetinae; Follicle Stimulating Hormone; gamma-Glutamyltransferase

2002
Changes in free polyamines and related enzymes during stipule and pod wall development in Pisum sativum.
    Indian journal of experimental biology, 2002, Volume: 40, Issue:8

    Topics: Aging; Amine Oxidase (Copper-Containing); Carboxy-Lyases; Chlorophyll; DNA, Plant; Electric Conducti

2002
SPERMIDINE AND SPERMINE IN RAT TISSUES AT DIFFERENT AGES.
    Acta physiologica Scandinavica, 1964, Volume: 62

    Topics: Adipose Tissue; Aging; Amines; Animals; Animals, Newborn; Brain; Coloring Agents; Electrophoresis; F

1964
The metabolites citrate, myo-inositol, and spermine are potential age-independent markers of prostate cancer in human expressed prostatic secretions.
    The Prostate, 2008, May-01, Volume: 68, Issue:6

    Topics: Adult; Aged; Aging; Area Under Curve; Biomarkers, Tumor; Body Fluids; Citric Acid; Humans; Inositol;

2008
Chromatin function in developing brain: acetylation of chromosomal proteins and RNA synthesis.
    Biochemical and biophysical research communications, 1981, May-15, Volume: 100, Issue:1

    Topics: Acetylation; Aging; Animals; Cerebral Cortex; Chromatin; Chromosomal Proteins, Non-Histone; Histones

1981
Developmental changes of the GABA and polyamine systems in isolated neurons in cell culture.
    Developmental neuroscience, 1981, Volume: 4, Issue:3

    Topics: Aging; Amino Acids; Animals; Cerebral Cortex; Chick Embryo; DNA; gamma-Aminobutyric Acid; Putrescine

1981
Acetylation of polyamines in chicken brain and retina.
    The International journal of biochemistry, 1984, Volume: 16, Issue:12

    Topics: Acetylation; Acetyltransferases; Aging; Alkaline Phosphatase; Animals; Brain; Chick Embryo; Chickens

1984
Changes of duodenal spermine-binding activity caused by vitamin D deficiency.
    Experientia, 1983, Feb-15, Volume: 39, Issue:2

    Topics: Aging; Animals; Calcitriol; Chickens; Duodenum; Spermine; Vitamin D Deficiency

1983
Changes in polyamines, RNA synthesis, and cell proliferation during matrix-induced cartilage, bone, and bone marrow development.
    Developmental biology, 1981, Volume: 82, Issue:2

    Topics: Adenosylmethionine Decarboxylase; Aging; Animals; Bone and Bones; Bone Marrow; Bone Transplantation;

1981
Toxic effects of maternal methadone administration on cardiac development in the neonatal rat: potential participation of altered polyamine levels in growth impairment.
    Toxicology letters, 1982, Volume: 14, Issue:3-4

    Topics: Aging; Animals; Animals, Newborn; Female; Heart; Methadone; Myocardium; Ornithine Decarboxylase; Pol

1982
Developmental changes in mouse brain polyamine metabolism.
    Neurochemical research, 1982, Volume: 7, Issue:12

    Topics: Adenosylmethionine Decarboxylase; Aging; Animals; Brain; Carboxy-Lyases; Kinetics; Mice; Mice, Inbre

1982
Polyamines modulate phosphorylation and acetylation of non-histone chromosomal proteins of the cerebral cortex of rats of various ages.
    Archives of gerontology and geriatrics, 1982, Volume: 1, Issue:4

    Topics: Acetylation; Aging; Animals; Cerebral Cortex; Chromosomal Proteins, Non-Histone; DNA; Histones; In V

1982
Polyamine accumulation in normal and denervated neonatal muscle.
    Experimental neurology, 1981, Volume: 72, Issue:3

    Topics: Aging; Animals; Animals, Newborn; Female; Male; Muscle Denervation; Muscles; Polyamines; Putrescine;

1981
Developmental change of the potentiation of NMDA response by spermine.
    Neuroreport, 1995, May-09, Volume: 6, Issue:7

    Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Drug Synergism; Electrophy

1995
Polyamines in human brain: regional distribution and influence of aging.
    Journal of neurochemistry, 1995, Volume: 65, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Animals; Brain; Child; Child, Preschool; Humans;

1995
Chronic neonatal blockade of NMDA receptor does not affect developmental polyamine metabolism but results in altered response to the excitotoxic induction of ornithine decarboxylase.
    Neurochemistry international, 1994, Volume: 24, Issue:6

    Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Animals, Newborn; Brain; Cerebellum; Cerebral Cortex; E

1994
Response of rat immature enterocytes to insulin: regulation by receptor binding and endoluminal polyamine uptake.
    Gastroenterology, 1994, Volume: 106, Issue:1

    Topics: Adrenalectomy; Aging; Animals; Animals, Newborn; Antibodies, Monoclonal; Eflornithine; Hydrolases; I

1994
Aging and polyamine acetylation in rat kidney.
    Biochimica et biophysica acta, 1996, Oct-07, Volume: 1317, Issue:1

    Topics: Acetylation; Acetyltransferases; Aging; Animals; Histones; Kidney; Male; Oxidoreductases Acting on C

1996
Fasting gastric fluid and fecal polyamine concentrations in premature infants.
    Journal of pediatric gastroenterology and nutrition, 1997, Volume: 24, Issue:4

    Topics: Aging; Cadaverine; Chromatography, High Pressure Liquid; Fasting; Feces; Gastric Juice; Gestational

1997
Spermine induces maturation of the immature intestinal immune system in neonatal mice.
    Journal of pediatric gastroenterology and nutrition, 1997, Volume: 25, Issue:3

    Topics: Aging; Animals; Animals, Newborn; beta-Galactosidase; CD4 Antigens; CD5 Antigens; Epithelial Cells;

1997
Regional variations in spermine levels in the developing rat brain following exposure to lead.
    Brain research bulletin, 1999, Jul-15, Volume: 49, Issue:5

    Topics: Aging; Animals; Animals, Newborn; Brain; Chromatography, High Pressure Liquid; Lead; Rats; Rats, Lon

1999
Distinct synaptic and extrasynaptic NMDA receptors in developing cerebellar granule neurons.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Dec-15, Volume: 19, Issue:24

    Topics: Aging; Animals; Animals, Newborn; Cerebellum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists

1999
Increased exon 5 expression alters extrasynaptic NMDA receptors in cerebellar neurons.
    Journal of neurochemistry, 2000, Volume: 75, Issue:3

    Topics: Aging; Alternative Splicing; Animals; Animals, Newborn; Cell Membrane; Cerebellum; Cerebral Cortex;

2000
Polyamines in the basal ganglia of human brain. Influence of aging and degenerative movement disorders.
    Neuroscience letters, 2001, May-18, Volume: 304, Issue:1-2

    Topics: Aged; Aged, 80 and over; Aging; Analysis of Variance; Basal Ganglia; Biogenic Polyamines; Female; Hu

2001
A hippocampal NR2B deficit can mimic age-related changes in long-term potentiation and spatial learning in the Fischer 344 rat.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, May-01, Volume: 22, Issue:9

    Topics: Action Potentials; Aging; Animals; Behavior, Animal; Blotting, Western; Calcium Channel Blockers; Ca

2002
Effects of polyamines on in vitro phosphorylation and acetylation of histones of the cerebral cortex of rats of various ages.
    Biochemical and biophysical research communications, 1979, Oct-12, Volume: 90, Issue:3

    Topics: Acetylation; Aging; Animals; Cerebral Cortex; Female; Histones; Phosphorylation; Rats; Spermidine; S

1979
Effect of age of rat on polyamine content of liver nuclei [proceedings].
    Biochemical Society transactions, 1977, Volume: 5, Issue:6

    Topics: Aging; Animals; Cell Nucleus; Liver; Polyamines; Rats; Spermidine; Spermine

1977
Analysis of spermidine and spermine in rat liver. Effect of hypophysectomy on polyamine concentrations.
    Canadian journal of biochemistry, 1978, Volume: 56, Issue:5

    Topics: Aging; Animals; Chromatography, Ion Exchange; Hypophysectomy; Liver; Male; Rats; Spermidine; Spermin

1978
Polyamines and ornithine decarboxylase activity in the developing rat retina.
    Life sciences, 1978, Aug-21, Volume: 23, Issue:7

    Topics: Aging; Animals; Animals, Newborn; Carboxy-Lyases; Eye Proteins; Female; Male; Ornithine Decarboxylas

1978
Polyamine metabolism in the brain and liver of the developing monkey.
    Journal of neurochemistry, 1975, Volume: 25, Issue:3

    Topics: Adenosylmethionine Decarboxylase; Aging; Animals; Brain; Female; Haplorhini; Liver; Macaca mulatta;

1975
Brain regional spermidine and spermine levels in relation to RNA and DNA in aging rat brain.
    Journal of neurochemistry, 1977, Volume: 28, Issue:3

    Topics: Aging; Animals; Brain; Brain Chemistry; Cerebral Cortex; Corpus Striatum; DNA; Hippocampus; Hypothal

1977
Polyamines of the human brain during normal fetal and postnatal growth and during postnatal malnutrition.
    Journal of neurochemistry, 1977, Volume: 28, Issue:6

    Topics: Aging; Brain; Brain Stem; Cerebellum; Child, Preschool; Female; Fetus; Gestational Age; Humans; Infa

1977
Changes in ornithine decarboxylase activity in rat intestines during aging.
    Cancer research, 1976, Volume: 36, Issue:9 pt.1

    Topics: Aging; Animals; Brain; Carboxy-Lyases; Female; Intestines; Kinetics; Liver; Male; Nucleotides; Ornit

1976
Interrelations between polyamines and nucleic acids: changes of polyamine and nucleic acid concentrations in the developing rat brain.
    Journal of neurochemistry, 1975, Volume: 24, Issue:1

    Topics: Aging; Animals; Brain; DNA; Nerve Tissue Proteins; Polyamines; Putrescine; Rats; RNA; Spermidine; Sp

1975
Changes of liver and kidney polyamine levels during aging.
    Experimental gerontology, 1975, Volume: 10, Issue:1

    Topics: Aging; Animals; Kidney; Liver; Male; Rats; Spermidine; Spermine

1975
Developmental expression of ornithine and S-adenosylmethionine decarboxylases in mouse brain.
    Biochemical and biophysical research communications, 1992, Apr-30, Volume: 184, Issue:2

    Topics: Adenosylmethionine Decarboxylase; Aging; Animals; Brain; DNA Probes; Gene Expression Regulation, Enz

1992
Development changes of polyamine biosynthesis in rat liver.
    Biology of the neonate, 1992, Volume: 62, Issue:6

    Topics: Acetyltransferases; Adenosylmethionine Decarboxylase; Aging; Animals; Animals, Newborn; Gestational

1992
Nuclear estradiol binding in rat adipocytes. Regional variations and regulatory influences of hormones.
    Biochimica et biophysica acta, 1991, Jun-07, Volume: 1093, Issue:1

    Topics: Adipose Tissue; Aging; Animals; Bucladesine; Cell Nucleus; Estradiol; Insulin; Isoproterenol; Kineti

1991
The effect of age on small bowel adaptation and growth after proximal enterectomy.
    Journal of gerontology, 1990, Volume: 45, Issue:6

    Topics: Adaptation, Physiological; Aging; Animals; Body Weight; DNA; Intestinal Mucosa; Intestine, Small; Ma

1990
Analysis of age-associated alteration in the synthesis of HMG nonhistone proteins of the rat liver.
    Molecular biology reports, 1991, Volume: 15, Issue:1

    Topics: Aging; Animals; Benzamides; Butyrates; Butyric Acid; Dexamethasone; Electrophoresis, Polyacrylamide

1991
[The effect of Cu2+, Zn2+ cations and biogenic amines on the nuclear poly(ADP-ribose) polymerase activity in the rat brain].
    Biokhimiia (Moscow, Russia), 1990, Volume: 55, Issue:4

    Topics: Aging; Animals; Biogenic Polyamines; Brain; Cations, Divalent; Cell Nucleus; Copper; Enzyme Activati

1990
ADP-ribosylation of HMG proteins and its modulation by different effectors in the liver of aging rats.
    Mechanisms of ageing and development, 1990, Mar-31, Volume: 53, Issue:1

    Topics: Adenosine Diphosphate Ribose; Aging; Animals; Benzamides; Butyrates; Butyric Acid; Dexamethasone; Hi

1990
Urinary excretion of polyamines: importance of circadian rhythm, age, sex, menstrual cycle, weight, and creatinine excretion.
    The American journal of clinical nutrition, 1990, Volume: 52, Issue:4

    Topics: Adult; Aging; Body Weight; Chromatography; Circadian Rhythm; Creatinine; Female; Humans; Male; Menst

1990
Allosteric activation of brain mitochondrial Ca2+ uptake by spermine and by Ca2+: developmental changes.
    Journal of neurochemistry, 1989, Volume: 53, Issue:4

    Topics: Aging; Allosteric Regulation; Animals; Brain; Calcium; Hippocampus; Kinetics; Mitochondria; Rats; Sp

1989
Age-related changes in the translocation of phosphatidate phosphohydrolase from the cytosol to microsomal membranes in rat liver.
    Biochimica et biophysica acta, 1988, Nov-25, Volume: 963, Issue:2

    Topics: Aging; Animals; Chlorpromazine; Cytosol; Intracellular Membranes; Kinetics; Liver; Male; Microsomes,

1988
Age-specific methylation of high-mobility-group proteins of the rat liver and its modulation by spermine and sodium butyrate.
    Mutation research, 1989, Volume: 219, Issue:2

    Topics: Aging; Animals; Butyrates; Butyric Acid; Chromatin; High Mobility Group Proteins; Liver; Male; Methi

1989
Changes of polyamine concentrations in infants during the first six months of life.
    Early human development, 1987, Volume: 15, Issue:6

    Topics: Aging; Diet; Female; Humans; Infant; Infant, Newborn; Male; Polyamines; Spermidine; Spermine

1987
Developmental aspects of polyamine interconversion in rat brain.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 1986, Volume: 4, Issue:3

    Topics: Aging; Animals; Blood-Brain Barrier; Brain; Female; Male; Oxidoreductases Acting on CH-NH Group Dono

1986
Developmental pattern of ornithine decarboxylase activity, S-adenosylmethionine decarboxylase, and polyamines of rat adrenal glands.
    Biology of the neonate, 1987, Volume: 51, Issue:5

    Topics: Adenosylmethionine Decarboxylase; Adrenal Glands; Aging; Animals; Carboxy-Lyases; Cold Temperature;

1987
Accumulation of polyamines and their weak association with lower body temperature in elderly convalescent patients.
    The Journal of laboratory and clinical medicine, 1987, Volume: 110, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aging; Body Temperature Regulation; Chromatography, High Pressure Li

1987
In vitro ADP-ribosylation of chromosomal proteins of the brain of developing rats.
    Molecular biology reports, 1986, Volume: 11, Issue:2

    Topics: Adenosine Diphosphate Ribose; Aging; Animals; Benzamides; Brain; Chromosomal Proteins, Non-Histone;

1986
Fetal calf serum-mediated toxicity of human polyamines to lymphocytes.
    Toxicology letters, 1986, Volume: 31, Issue:3

    Topics: Aging; Cell Survival; Humans; In Vitro Techniques; Lymphocytes; Mitogens; Polyamines; Putrescine; Sp

1986
Polyamine effects on 14C-leucine transfer to microsomal protein in a rat liver cell free system during ageing.
    Experimental gerontology, 1973, Volume: 8, Issue:6

    Topics: Aging; Animals; Carbon Radioisotopes; Cell-Free System; Centrifugation; Cytoplasm; Isotope Labeling;

1973
Polyamines. (1) Enhanced s-adenosyl-L-methionine decarboxylase in rapid growth systems, and (2) the relationships between polyamine concentration and RNA accumulation.
    Biochimica et biophysica acta, 1971, Jun-30, Volume: 240, Issue:2

    Topics: Aging; Amines; Animals; Carbon Isotopes; Carboxy-Lyases; Chemical Phenomena; Chemistry; Chick Embryo

1971