Page last updated: 2024-10-20

spermine and Adenoma, Prostatic

spermine has been researched along with Adenoma, Prostatic in 14 studies

Research Excerpts

ExcerptRelevanceReference
" Tissue concentrations of polyamines can be detected by cation exchange analysis and putrescine, spermine and spermidine were assayed in specimens of benign hyperplasia of prostate and renal adenocarcinoma and in normal control tissues."3.66Determination of putrescine, spermine and spermidine in human tissues of prostate and kidney. ( Dunzendorfer, U; Russell, DH, 1980)
"PCa, benign prostatic hyperplasia (BPH) patients and healthy controls (HC) showing PSA>4."1.43Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers. ( Chan, CF; Chan, WL; Chiu, KF; Ng, CF; Tsoi, TH; Wong, KL; Wong, WT, 2016)
"Spermine levels were reduced in tumor tissue, especially in prostatic carcinoma with metastases, and in xenografts of human prostatic carcinoma cells."1.31Proton MR spectroscopy of prostatic tissue focused on the detection of spermine, a possible biomarker of malignant behavior in prostate cancer. ( Heerschap, A; Oosterhof, GO; Schalken, JA; Schipper, RG; van der Graaf, M; Verhofstad, AA, 2000)
"All 6 patients with localized malignant tumors had elevated urinary polyamine levels."1.25Urinary polyamine levels in human cancer. ( Kessler, GF; Lipton, A; Sheehan, LM, 1975)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19908 (57.14)18.7374
1990's2 (14.29)18.2507
2000's2 (14.29)29.6817
2010's1 (7.14)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Zaletok, SP1
Klenov, OO1
Bentrad, VV1
Prylutskyi, MP1
Vitruk, YV1
Stakhovsky, EO1
Timoshenko, AV1
Tsoi, TH1
Chan, CF1
Chan, WL1
Chiu, KF1
Wong, WT1
Ng, CF1
Wong, KL1
Yue, K1
Marumoto, A1
Binesh, N1
Thomas, MA1
Dunzendorfer, U5
Russell, DH3
Harper, ME1
Chaisiri, P1
Slade, J1
Peeling, WB1
Griffiths, K1
van der Graaf, M1
Schipper, RG1
Oosterhof, GO1
Schalken, JA1
Verhofstad, AA1
Heerschap, A1
Lipton, A1
Sheehan, LM1
Kessler, GF1
Cipolla, B2
Guille, F2
Quemener, V2
Lévêque, JM1
Moulinoux, JP2
Lobel, B2
Havouis, R1
Martin, LA1
Knöner, M1
Sakai, S1
Ito, Y1
Koide, T1
Tei, K1
Hara, A1
Sawada, H1

Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Artificial Intelligence (AI)-Assisted Risk-based Prostate Cancer Detection: A Synergy of Novel Biomarkers, Advanced Imaging, and Robotic-assisted Diagnosis[NCT05443412]510 participants (Anticipated)Observational2022-08-01Not yet recruiting
To Evaluate the Performance of a Urine Spermine Measuring Device in Predicting Prostate Biopsy Result[NCT04339920]0 participants (Actual)Observational2021-09-01Withdrawn (stopped due to No funding)
To Investigate the Diagnostic Accuracy of Exosomal microRNA in Predicting the Aggressiveness of Prostate Cancer in Chinese Patients[NCT03911999]180 participants (Actual)Observational2018-05-03Completed
To Identify Potential New Urine Marker Panel for Cancer Screening[NCT04689802]2,500 participants (Anticipated)Observational2021-01-20Recruiting
To Investigate the Role of Gut Microbiome in Androgen Deprivation Therapy Related Metabolic Changes in Prostate Cancer Patients[NCT04687709]50 participants (Anticipated)Observational2021-01-14Recruiting
The Investigation of New Biological Markers for Prostate Cancer Diagnosis and Management in Chinese Population[NCT03893929]5,000 participants (Anticipated)Observational2015-10-07Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for spermine and Adenoma, Prostatic

ArticleYear
Prostate cancer. Hormonal relationships, receptors, and tumour markers.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1981, Volume: 78

    Topics: Acid Phosphatase; Aged; Androgens; Humans; Male; Polyamines; Prostatic Hyperplasia; Prostatic Neopla

1981

Other Studies

13 other studies available for spermine and Adenoma, Prostatic

ArticleYear
POLYAMINES AS NEW POTENTIAL BIOMARKERS FOR DIFFERENTIAL DIAGNOSIS OF PROSTATE CANCER AND ESTIMATION OF ITS AGGRESSIVENESS.
    Experimental oncology, 2022, Volume: 44, Issue:2

    Topics: Aged; Biomarkers; Diagnosis, Differential; Humans; Male; Polyamines; Prostatic Hyperplasia; Prostati

2022
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
2D JPRESS of human prostates using an endorectal receiver coil.
    Magnetic resonance in medicine, 2002, Volume: 47, Issue:6

    Topics: Adult; Biomarkers, Tumor; Choline; Citric Acid; Creatine; Humans; Magnetic Resonance Spectroscopy; M

2002
Determination of putrescine, spermine and spermidine in human tissues of prostate and kidney.
    Arzneimittel-Forschung, 1980, Volume: 30, Issue:10

    Topics: Adenocarcinoma; Adult; Humans; Kidney; Kidney Neoplasms; Male; Polyamines; Prostate; Prostatic Hyper

1980
[Therapy of prostate carcinoma with polyamine synthesis inhibitors. I. Physiological and pathophysiological principles].
    Urologia internationalis, 1982, Volume: 37, Issue:5

    Topics: Antineoplastic Agents; Humans; Male; Polyamines; Prostatic Hyperplasia; Prostatic Neoplasms; Putresc

1982
Proton MR spectroscopy of prostatic tissue focused on the detection of spermine, a possible biomarker of malignant behavior in prostate cancer.
    Magma (New York, N.Y.), 2000, Volume: 10, Issue:3

    Topics: Biomarkers, Tumor; Chromatography, High Pressure Liquid; Humans; Magnetic Resonance Spectroscopy; Ma

2000
Urinary polyamine levels in human cancer.
    Cancer, 1975, Volume: 35, Issue:2

    Topics: Adenocarcinoma; Adenoma; Bone Neoplasms; Breast Neoplasms; Bronchial Neoplasms; Carcinoma, Squamous

1975
Altered polyamine profiles in prostatic hyperplasia and in kidney tumors.
    Cancer research, 1978, Volume: 38, Issue:8

    Topics: Adult; Aged; Female; Humans; Kidney; Kidney Neoplasms; Male; Middle Aged; Polyamines; Prostate; Pros

1978
Altered polyamines and peptide hormones (FSH, TSH, prolactin, C-peptide) in prostatic hyperplasia and kidney tumors.
    Cellular and molecular biology, including cyto-enzymology, 1979, Volume: 24, Issue:4

    Topics: C-Peptide; Follicle Stimulating Hormone; Humans; Kidney; Kidney Neoplasms; Male; Peptides; Polyamine

1979
[The diagnostic value of erythrocyte polyamines (EPA) in prostatic adenocarcinoma (PA): apropos of 100 patients].
    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie, 1992, Volume: 2, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Erythrocytes; Humans; Male; Middl

1992
Erythrocyte polyamine levels in human prostatic carcinoma.
    The Journal of urology, 1990, Volume: 144, Issue:5

    Topics: Adenocarcinoma; Aged; Chromatography, High Pressure Liquid; Erythrocytes; Humans; Male; Prostatic Hy

1990
[Therapy with inhibitors of polyamine biosynthesis in refractory prostatic carcinoma. An experimental and clinical study].
    Onkologie, 1985, Volume: 8, Issue:4

    Topics: Adenocarcinoma; Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; Carboxy-Lyases; Ca

1985
[Detection of urinary polyamine by a new enzymatic differential assay. (III). Studies on urinary polyamines in patients with malignant genitourinary diseases].
    Hinyokika kiyo. Acta urologica Japonica, 1986, Volume: 32, Issue:3

    Topics: Diamines; Humans; Kidney Neoplasms; Male; Polyamines; Prostatic Hyperplasia; Prostatic Neoplasms; Sp

1986