spermine has been researched along with Adenocarcinoma, Basal Cell in 46 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " Exogenous spermine and ZmPAO treatment decreased cell viability in a spermine dose‑ and time‑dependent manner, particularly, the viability of the multidrug‑resistant (MDR) colon adenocarcinoma cells, LoVo DX, when compared with drug‑sensitive ones (LoVo WT)." | 7.91 | Maize polyamine oxidase in the presence of spermine/spermidine induces the apoptosis of LoVo human colon adenocarcinoma cells. ( Agostinelli, E; Angelini, R; Canettieri, G; Cona, A; Gaudio, E; Mancinelli, R; Miglietta, S; Ohkubo, S; Spandidos, DA, 2019) |
| "Using three cytotoxicity assays, we have investigated the effect of the spermine analogue N1,N11-diethylnorspermine (DENSPM) on four human breast cancer cell lines with different known genetic lesions." | 7.73 | Comparison of three cytotoxicity tests in the evaluation of the cytotoxicity of a spermine analogue on human breast cancer cell lines. ( Holst, CM; Oredsson, SM, 2005) |
| " We investigated a new strategy to overcome multidrug resistance (MDR) cancer cells, using bovine serum amine oxidase (BSAO), which forms toxic products from spermine (H2O2 and aldehydes)." | 5.33 | Hyperthermia enhances cytotoxicity of amine oxidase and spermine on drug-resistant LoVo colon adenocarcinoma cells. ( Agostinelli, E; Arancia, G; Belli, F; Crateri, P; Dalla Vedova, L; Marra, M, 2006) |
| "Histamine was detected in 3 of the 6 cases of thyroid carcinomas, and in case of adenomatous goiter." | 5.26 | Elevated levels of polyamines and histamine in adenocarcinomas of the thyroid. ( Hamana, K; Itoh, K; Matsuzaki, S; Suzuki, M, 1978) |
| " Exogenous spermine and ZmPAO treatment decreased cell viability in a spermine dose‑ and time‑dependent manner, particularly, the viability of the multidrug‑resistant (MDR) colon adenocarcinoma cells, LoVo DX, when compared with drug‑sensitive ones (LoVo WT)." | 3.91 | Maize polyamine oxidase in the presence of spermine/spermidine induces the apoptosis of LoVo human colon adenocarcinoma cells. ( Agostinelli, E; Angelini, R; Canettieri, G; Cona, A; Gaudio, E; Mancinelli, R; Miglietta, S; Ohkubo, S; Spandidos, DA, 2019) |
| " Here, extending earlier work on bisnaphthalimidopropylspermidine (BNIPSpd)-induced apoptosis in colon adenocarcinoma Caco-2 cells, we compare the cytotoxicity and genotoxicity of BNIPSpd relative to the spermine and oxaspermine derivatives, bisnaphthalimidopropylspermine (BNIPSpm) and bisnaphthalimidopropyloxaspermine (BNIPOSpm)." | 3.77 | The influence of bisnaphthalimidopropyl polyamines on DNA instability and repair in Caco-2 colon epithelial cells. ( Bestwick, CS; Duthie, SJ; Kong Thoo Lin, P; Milne, L; Ralton, LD, 2011) |
| "Using three cytotoxicity assays, we have investigated the effect of the spermine analogue N1,N11-diethylnorspermine (DENSPM) on four human breast cancer cell lines with different known genetic lesions." | 3.73 | Comparison of three cytotoxicity tests in the evaluation of the cytotoxicity of a spermine analogue on human breast cancer cell lines. ( Holst, CM; Oredsson, SM, 2005) |
| " The present results show that multidrug-resistant human colon adenocarcinoma cells (LoVo) are significantly more sensitive than corresponding wild-type cells to hydrogen peroxide and aldehydes, the products of bovine serum amine oxidase (BSAO)-catalyzed oxidation of spermine." | 3.73 | Sensitization of human colon adenocarcinoma cells (LoVo) to reactive oxygen species by a lysosomotropic compound. ( Agostinelli, E; Arancia, G; Belli, F; Condello, M; Seiler, N; Vedova, LD, 2006) |
| "This 52-year-old male without a significant medical history was receiving chemotherapy with diethylnorspermine (DENSPM), a polyamine analogue, for a partially resected pancreatic adenocarcinoma." | 3.70 | Chemotherapy for pancreatic cancer: a neuroimaging clinicopathologic correlation. ( Rojiani, AM; Valenstein, EJ; Williams, LS, 1999) |
| "We evaluated polyamine (putrescine, spermidine, and spermine) levels, estrogen receptor concentrations, and their relationship in neoplastic tissue and surrounding mucosa from 30 patients with gastric adenocarcinoma." | 3.69 | Estrogen receptors and polyamine levels in human gastric carcinoma. ( Cavallini, A; Di Leo, A; Linsalata, M; Messa, C; Russo, F, 1994) |
| "We assayed the estrogen receptors and polyamine levels (putrescine, spermidine and spermine) in the neoplastic and "normal" surrounding tissue of patients with colorectal cancer." | 3.68 | Polyamines and estrogen-receptor concentrations in human colorectal carcinomas. ( Cavallini, A; Di Leo, A; Guerra, V; Lacatena, M; Lantone, G; Linsalata, M; Messa, C; Notarnicola, M; Russo, F, 1992) |
| " Tissue concentrations of polyamines can be detected by cation exchange analysis and putrescine, spermine and spermidine were assayed in specimens of benign hyperplasia of prostate and renal adenocarcinoma and in normal control tissues." | 3.66 | Determination of putrescine, spermine and spermidine in human tissues of prostate and kidney. ( Dunzendorfer, U; Russell, DH, 1980) |
| "Fifteen patients with advanced solid tumors were entered into a phase I study of DENSPM given by a 1 h i." | 2.68 | Unusual central nervous system toxicity in a phase I study of N1N11 diethylnorspermine in patients with advanced malignancy. ( Berghorn, E; Creaven, PJ; Levine, E; Loewen, G; Meropol, NJ; Pendyala, L; Perez, R; Raghavan, D, 1997) |
| "Treatment of human breast cancer cell lines in culture with these analogues has been shown to decrease cell proliferation and induce programmed cell death." | 2.40 | Clinical aspects of cell death in breast cancer: the polyamine pathway as a new target for treatment. ( Casero, RA; Davidson, NE; Hahm, HA; McCloskey, DE; Woster, PM, 1999) |
| " We investigated a new strategy to overcome multidrug resistance (MDR) cancer cells, using bovine serum amine oxidase (BSAO), which forms toxic products from spermine (H2O2 and aldehydes)." | 1.33 | Hyperthermia enhances cytotoxicity of amine oxidase and spermine on drug-resistant LoVo colon adenocarcinoma cells. ( Agostinelli, E; Arancia, G; Belli, F; Crateri, P; Dalla Vedova, L; Marra, M, 2006) |
| " In vitro studies indicated that the growth sensitivity of most tumor cell lines to DENSPM was similar, with characteristically flat dose-response curves and IC50s ranging between 0." | 1.29 | Preclinical antitumor efficacy of the polyamine analogue N1, N11-diethylnorspermine administered by multiple injection or continuous infusion. ( Atwood, A; Bergeron, RJ; Bernacki, RJ; Oberman, EJ; Porter, CW; Seweryniak, KE, 1995) |
| "Histamine was detected in 3 of the 6 cases of thyroid carcinomas, and in case of adenomatous goiter." | 1.26 | Elevated levels of polyamines and histamine in adenocarcinomas of the thyroid. ( Hamana, K; Itoh, K; Matsuzaki, S; Suzuki, M, 1978) |
| "All 6 patients with localized malignant tumors had elevated urinary polyamine levels." | 1.25 | Urinary polyamine levels in human cancer. ( Kessler, GF; Lipton, A; Sheehan, LM, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (23.91) | 18.7374 |
| 1990's | 19 (41.30) | 18.2507 |
| 2000's | 9 (19.57) | 29.6817 |
| 2010's | 6 (13.04) | 24.3611 |
| 2020's | 1 (2.17) | 2.80 |
| Authors | Studies |
|---|---|
| Sierra, JC | 1 |
| Piazuelo, MB | 1 |
| Luis, PB | 1 |
| Barry, DP | 1 |
| Allaman, MM | 1 |
| Asim, M | 1 |
| Sebrell, TA | 1 |
| Finley, JL | 1 |
| Rose, KL | 1 |
| Hill, S | 1 |
| Holshouser, SL | 1 |
| Casero, RA | 3 |
| Cleveland, JL | 1 |
| Woster, PM | 2 |
| Schey, KL | 1 |
| Bimczok, D | 1 |
| Schneider, C | 1 |
| Gobert, AP | 1 |
| Wilson, KT | 1 |
| Ohkubo, S | 1 |
| Mancinelli, R | 1 |
| Miglietta, S | 1 |
| Cona, A | 1 |
| Angelini, R | 1 |
| Canettieri, G | 1 |
| Spandidos, DA | 1 |
| Gaudio, E | 1 |
| Agostinelli, E | 5 |
| Kato, M | 1 |
| Onishi, H | 1 |
| Matsumoto, K | 1 |
| Motoshita, J | 1 |
| Tsuruta, N | 1 |
| Higuchi, K | 1 |
| Katano, M | 1 |
| Wang, Z | 2 |
| Zou, H | 1 |
| Wu, J | 1 |
| Xia, Z | 1 |
| Feng, M | 1 |
| García-Martín, ML | 1 |
| Adrados, M | 1 |
| Ortega, MP | 1 |
| Fernández González, I | 1 |
| López-Larrubia, P | 1 |
| Viaño, J | 1 |
| García-Segura, JM | 1 |
| Bestwick, CS | 1 |
| Ralton, LD | 1 |
| Milne, L | 1 |
| Kong Thoo Lin, P | 1 |
| Duthie, SJ | 1 |
| Jiang, HL | 1 |
| Hong, SH | 1 |
| Kim, YK | 1 |
| Islam, MA | 1 |
| Kim, HJ | 1 |
| Choi, YJ | 1 |
| Nah, JW | 1 |
| Lee, KH | 1 |
| Han, KW | 1 |
| Chae, C | 1 |
| Cho, CS | 1 |
| Cho, MH | 1 |
| Watts, RN | 1 |
| Richardson, DR | 1 |
| Arancia, G | 4 |
| Calcabrini, A | 2 |
| Marra, M | 3 |
| Crateri, P | 3 |
| Artico, M | 1 |
| Martone, A | 2 |
| Martelli, F | 1 |
| Holst, CM | 1 |
| Oredsson, SM | 1 |
| Belli, F | 2 |
| Dalla Vedova, L | 1 |
| Vedova, LD | 1 |
| Condello, M | 1 |
| Seiler, N | 1 |
| Moulinoux, JP | 3 |
| Quemener, V | 3 |
| Larzul, JJ | 1 |
| Le Calve, M | 1 |
| Roch, AM | 1 |
| Toujas, L | 1 |
| Quash, G | 1 |
| Dunzendorfer, U | 2 |
| Russell, DH | 1 |
| Smith, RC | 1 |
| Litwin, MS | 1 |
| Lu, Y | 1 |
| Zetter, BR | 1 |
| Milovic, V | 2 |
| Deubner, C | 1 |
| Zeuzem, S | 1 |
| Piiper, A | 1 |
| Caspary, WF | 2 |
| Stein, J | 2 |
| Gabrielson, EW | 1 |
| Pegg, AE | 1 |
| Linsalata, M | 3 |
| Messa, C | 2 |
| Russo, F | 3 |
| Cavallini, A | 3 |
| Di Leo, A | 3 |
| Capaccioli, S | 1 |
| Di Pasquale, G | 1 |
| Mini, E | 1 |
| Mazzei, T | 1 |
| Quattrone, A | 1 |
| Berloco, P | 1 |
| Gray, MR | 1 |
| Wallace, HM | 2 |
| Goulding, H | 1 |
| Hoffman, J | 1 |
| Kenyon, WE | 1 |
| Kingsnorth, AN | 1 |
| Creaven, PJ | 1 |
| Perez, R | 1 |
| Pendyala, L | 1 |
| Meropol, NJ | 1 |
| Loewen, G | 1 |
| Levine, E | 1 |
| Berghorn, E | 1 |
| Raghavan, D | 1 |
| Zagaja, GP | 1 |
| Shrivastav, M | 1 |
| Fleig, MJ | 1 |
| Marton, LJ | 1 |
| Rinker-Schaeffer, CW | 1 |
| Dolan, ME | 1 |
| Bernacki, RJ | 1 |
| Oberman, EJ | 1 |
| Seweryniak, KE | 1 |
| Atwood, A | 1 |
| Bergeron, RJ | 3 |
| Porter, CW | 3 |
| Rojiani, AM | 1 |
| Williams, LS | 1 |
| Valenstein, EJ | 1 |
| Davidson, NE | 1 |
| Hahm, HA | 1 |
| McCloskey, DE | 1 |
| Teller, IC | 1 |
| Turchanowa, L | 1 |
| Schleiffer, R | 1 |
| Duranton, B | 1 |
| Gossé, F | 1 |
| Hasselmann, M | 1 |
| Raul, F | 1 |
| Cohen, RJ | 1 |
| Fujiwara, K | 1 |
| Holland, JW | 1 |
| McNeal, JE | 1 |
| Befani, O | 1 |
| Lipton, A | 2 |
| Sheehan, LM | 1 |
| Kessler, GF | 2 |
| Matsuzaki, S | 1 |
| Suzuki, M | 1 |
| Hamana, K | 1 |
| Itoh, K | 1 |
| Matsuda, M | 1 |
| Osafune, M | 1 |
| Kotake, T | 1 |
| Sonoda, T | 1 |
| Sobue, K | 1 |
| Nakajima, T | 1 |
| Nishioka, K | 1 |
| Romsdahl, MM | 1 |
| Sanford, EJ | 1 |
| Drago, JR | 1 |
| Rohner, TJ | 1 |
| Sheehan, L | 1 |
| Cipolla, B | 2 |
| Guille, F | 2 |
| Lévêque, JM | 1 |
| Lobel, B | 2 |
| Twentyman, PR | 1 |
| Wright, KA | 1 |
| Notarnicola, M | 1 |
| Guerra, V | 1 |
| Lantone, G | 1 |
| Lacatena, M | 1 |
| Chang, BK | 2 |
| Liang, Y | 2 |
| Vinson, JR | 1 |
| Libby, PR | 1 |
| Havouis, R | 1 |
| Martin, LA | 1 |
| Becciolini, A | 1 |
| Porciani, S | 1 |
| Lanini, A | 1 |
| Balzi, M | 1 |
| Cionini, L | 1 |
| Bandettini, L | 1 |
| Knöner, M | 1 |
| Hawrylewicz, EJ | 1 |
| Moshovitis, CK | 1 |
| Reger, C | 1 |
| Madell, J | 1 |
| Levasseur, S | 1 |
| Poleck, T | 1 |
| Shaw, M | 1 |
| Guinan, P | 1 |
| Burke, G | 1 |
| LaMuraglia, GM | 1 |
| Lacaine, F | 1 |
| Malt, RA | 1 |
1 review available for spermine and Adenocarcinoma, Basal Cell
| Article | Year |
|---|---|
Clinical aspects of cell death in breast cancer: the polyamine pathway as a new target for treatment.
Topics: Acetyltransferases; Adenocarcinoma; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Divisio | 1999 |
1 trial available for spermine and Adenocarcinoma, Basal Cell
| Article | Year |
|---|---|
Unusual central nervous system toxicity in a phase I study of N1N11 diethylnorspermine in patients with advanced malignancy.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Area Under Curve; Biological Availability; Centr | 1997 |
44 other studies available for spermine and Adenocarcinoma, Basal Cell
| Article | Year |
|---|---|
Spermine oxidase mediates Helicobacter pylori-induced gastric inflammation, DNA damage, and carcinogenic signaling.
Topics: Adenocarcinoma; Animals; beta Catenin; Cell Transformation, Neoplastic; DNA Damage; Gastritis; Helic | 2020 |
Maize polyamine oxidase in the presence of spermine/spermidine induces the apoptosis of LoVo human colon adenocarcinoma cells.
Topics: Adenocarcinoma; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colonic Neoplasms; Dose-Respons | 2019 |
Prognostic significance of urine N1, N12-diacetylspermine in patients with non-small cell lung cancer.
Topics: Adenocarcinoma; Aged; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; F | 2014 |
Highly stable polyglutamate derivatives/siRNA polyplex efficiently down-relegate survivin expression and augment the efficacy of cisplatin.
Topics: Adenocarcinoma; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cisplatin; | 2016 |
Quantitative (1) H MR spectroscopic imaging of the prostate gland using LCModel and a dedicated basis-set: correlation with histologic findings.
Topics: Adenocarcinoma; Choline; Citric Acid; Creatine; Humans; In Vitro Techniques; Magnetic Resonance Spec | 2011 |
The influence of bisnaphthalimidopropyl polyamines on DNA instability and repair in Caco-2 colon epithelial cells.
Topics: Adenocarcinoma; Apoptosis; Caco-2 Cells; Cell Survival; Colonic Neoplasms; Comet Assay; DNA; DNA Dam | 2011 |
Aerosol delivery of spermine-based poly(amino ester)/Akt1 shRNA complexes for lung cancer gene therapy.
Topics: Acrylates; Adenocarcinoma; Adenocarcinoma of Lung; Aerosols; Animals; Cell Line, Tumor; Cross-Linkin | 2011 |
The mechanism of nitrogen monoxide (NO)-mediated iron mobilization from cells. NO intercepts iron before incorporation into ferritin and indirectly mobilizes iron from ferritin in a glutathione-dependent manner.
Topics: Adenocarcinoma; Animals; Breast Neoplasms; Cell Membrane Permeability; Cell-Free System; Cytosol; De | 2002 |
Mitochondrial alterations induced by serum amine oxidase and spermine on human multidrug resistant tumor cells.
Topics: Adenocarcinoma; Amine Oxidase (Copper-Containing); Animals; Cattle; Cell Line, Tumor; Cell Survival; | 2004 |
Comparison of three cytotoxicity tests in the evaluation of the cytotoxicity of a spermine analogue on human breast cancer cell lines.
Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Survival; | 2005 |
Hyperthermia enhances cytotoxicity of amine oxidase and spermine on drug-resistant LoVo colon adenocarcinoma cells.
Topics: Adenocarcinoma; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Drug Resistance, Neoplasm; Human | 2006 |
Sensitization of human colon adenocarcinoma cells (LoVo) to reactive oxygen species by a lysosomotropic compound.
Topics: Adenocarcinoma; Aldehydes; Amine Oxidase (Copper-Containing); Animals; Antineoplastic Combined Chemo | 2006 |
Red blood cell polyamines in mice bearing the Lewis lung carcinoma (3LL) and in patients with bronchopulmonary cancers.
Topics: Adenocarcinoma; Adult; Aged; Animals; Bronchial Neoplasms; Carcinoma, Small Cell; Carcinoma, Squamou | 1984 |
Determination of putrescine, spermine and spermidine in human tissues of prostate and kidney.
Topics: Adenocarcinoma; Adult; Humans; Kidney; Kidney Neoplasms; Male; Polyamines; Prostate; Prostatic Hyper | 1980 |
Identification of an endogenous inhibitor of prostatic carcinoma cell growth.
Topics: Adenocarcinoma; Animals; Enzyme Inhibitors; Growth Inhibitors; Guanidines; Humans; Male; Neoplasm In | 1995 |
EGF stimulates polyamine uptake in Caco-2 cells.
Topics: Adenocarcinoma; Biological Transport; Cell Differentiation; Colonic Neoplasms; Cycloheximide; Epider | 1995 |
Immunohistochemical staining of human spermidine/spermine N1-acetyltransferase superinduced in response to treatment with antitumor polyamine analogues.
Topics: Acetyltransferases; Adenocarcinoma; Animals; Antibodies; Antineoplastic Agents; Drug Screening Assay | 1994 |
Estrogen receptors and polyamine levels in human gastric carcinoma.
Topics: Adenocarcinoma; Biogenic Polyamines; Female; Gastric Mucosa; Humans; Male; Middle Aged; Putrescine; | 1994 |
Cationic lipids improve antisense oligonucleotide uptake and prevent degradation in cultured cells and in human serum.
Topics: 3T3 Cells; Adenocarcinoma; Animals; Base Sequence; Biological Transport; Cell Line; Colonic Neoplasm | 1993 |
Polyamines, diamine oxidase, and ornithine decarboxylase activity in colorectal cancer and in normal surrounding mucosa.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Amine Oxidase (Copper-Containing); Biomarkers, Tumor | 1993 |
Mucosal polyamine metabolism in the columnar lined oesophagus.
Topics: Adenocarcinoma; Barrett Esophagus; Biomarkers; Chromatography, High Pressure Liquid; Esophageal Neop | 1993 |
Effects of polyamine analogues on prostatic adenocarcinoma cells in vitro and in vivo.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Cell Survival; Dose-Response Relationship | 1998 |
Preclinical antitumor efficacy of the polyamine analogue N1, N11-diethylnorspermine administered by multiple injection or continuous infusion.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Division; Colonic Neoplasms; Drug Administratio | 1995 |
Chemotherapy for pancreatic cancer: a neuroimaging clinicopathologic correlation.
Topics: Adenocarcinoma; Antineoplastic Agents; Brain; Brain Neoplasms; Demyelinating Diseases; Diagnosis, Di | 1999 |
Effect of structural analogues of propionate and butyrate on colon cancer cell growth.
Topics: Adenocarcinoma; Apoptosis; Bromine; Butyrates; Cell Division; Colonic Neoplasms; DNA Damage; DNA, Su | 2000 |
Blood polyamine levels after oral ornithine load, a diagnostic marker of hyperproliferative premalignant and malignant stages in a model of colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Biomarkers, Tumor; Biotransformation; Body | 2000 |
Polyamines in prostatic epithelial cells and adenocarcinoma; the effects of androgen blockade.
Topics: Adenocarcinoma; Androgen Antagonists; Eosinophils; Epithelial Cells; Humans; Immunohistochemistry; M | 2001 |
Enzymatic oxidation products of spermine induce greater cytotoxic effects on human multidrug-resistant colon carcinoma cells (LoVo) than on their wild-type counterparts.
Topics: Adenocarcinoma; Aldehyde Dehydrogenase; Amine Oxidase (Copper-Containing); ATP Binding Cassette Tran | 2002 |
Urinary polyamine levels in human cancer.
Topics: Adenocarcinoma; Adenoma; Bone Neoplasms; Breast Neoplasms; Bronchial Neoplasms; Carcinoma, Squamous | 1975 |
Elevated levels of polyamines and histamine in adenocarcinomas of the thyroid.
Topics: Adenocarcinoma; Adenoma; Adult; DNA; Female; Graves Disease; Histamine; Humans; Middle Aged; Polyami | 1978 |
Concentrations of polyamines in renal cell carcinoma.
Topics: Adenocarcinoma; Adult; Aged; DNA, Neoplasm; Female; Humans; Kidney; Kidney Neoplasms; Male; Middle A | 1978 |
Preliminary longitudinal studies of serum polyamines in patients with colorectal carcinoma.
Topics: Adenocarcinoma; Colonic Neoplasms; Humans; Intestinal Polyps; Longitudinal Studies; Middle Aged; Pro | 1977 |
Preliminary evaluation of urinary polyamines in the diagnosis of genitourinary tract malignancy.
Topics: Adenocarcinoma; Carcinoma, Transitional Cell; Female; Humans; Kidney Neoplasms; Male; Polyamines; Pr | 1975 |
[The diagnostic value of erythrocyte polyamines (EPA) in prostatic adenocarcinoma (PA): apropos of 100 patients].
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Erythrocytes; Humans; Male; Middl | 1992 |
Effects of cyclosporin A and a non-immunosuppressive analogue, O-acetyl cyclosporin A, upon the growth of parent and multidrug resistant human lung cancer cells in vitro.
Topics: Adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Division; Cell Line; Cel | 1992 |
Polyamines and estrogen-receptor concentrations in human colorectal carcinomas.
Topics: Adenocarcinoma; Adult; Aged; Carcinoembryonic Antigen; Colorectal Neoplasms; Female; Humans; Intesti | 1992 |
Antitumor effects of N-alkylated polyamine analogues in human pancreatic adenocarcinoma models.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Humans; Male; Mice; Mice, Nude; Neoplasm Transplanta | 1992 |
Regulatory and antiproliferative effects of N-alkylated polyamine analogues in human and hamster pancreatic adenocarcinoma cell lines.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cricetinae; Humans; Mesocricetus; Pancreatic Neoplas | 1992 |
Erythrocyte polyamine levels in human prostatic carcinoma.
Topics: Adenocarcinoma; Aged; Chromatography, High Pressure Liquid; Erythrocytes; Humans; Male; Prostatic Hy | 1990 |
Polyamine levels in healthy and tumor tissues of patients with colon adenocarcinoma.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Chromatography, High Pressure Liquid; Colon; Colonic | 1991 |
[Therapy with inhibitors of polyamine biosynthesis in refractory prostatic carcinoma. An experimental and clinical study].
Topics: Adenocarcinoma; Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; Carboxy-Lyases; Ca | 1985 |
Dietary protein enhanced mammary ornithine decarboxylase activity and tumorigenesis in rats.
Topics: Adenocarcinoma; Animals; Dietary Proteins; Epithelium; Female; Liver; Mammary Glands, Animal; Mammar | 1989 |
The effects of polyamine antimetabolites on polyamine-responsive casein kinase activity.
Topics: Adenocarcinoma; Adenosylmethionine Decarboxylase; Alkynes; Animals; Antineoplastic Agents; Casein Ki | 1987 |
High ornithine decarboxylase activity and polyamine levels in human colorectal neoplasia.
Topics: Adenocarcinoma; Cell Differentiation; Colonic Neoplasms; Humans; Intestinal Mucosa; Intestinal Polyp | 1986 |