Page last updated: 2024-10-20

spermine and Acute Edematous Pancreatitis

spermine has been researched along with Acute Edematous Pancreatitis in 8 studies

Research Excerpts

ExcerptRelevanceReference
" Our experimental studies have shown that catabolism of spermidine and spermine to putrescine is associated with the development of pancreatitis."7.74A polyamine analog bismethylspermine ameliorates severe pancreatitis induced by intraductal infusion of taurodeoxycholate. ( Alhonen, L; Grigorenko, N; Herzig, KH; Hyvönen, MT; Jin, HT; Khomutov, AR; Lämsä, T; Nordback, I; Räty, S; Sand, J, 2008)
"Experimental pancreatitis is associated with activation of polyamine catabolism."5.37Association between remote organ injury and tissue polyamine homeostasis in acute experimental pancreatitis - treatment with a polyamine analogue bismethylspermine. ( Alhonen, L; Grigorenko, N; Hyvönen, MT; Jin, HT; Khomutov, AR; Lämsä, T; Nordback, I; Nordback, PH; Pörsti, I; Räty, S; Sand, J, 2011)
"Pancreatitis was induced in wild-type rats by 2 or 6% taurodeoxycholate infusion or in transgenic rats by overexpressing spermidine/spermine N(1)-acetyltransferase (SSAT)."3.77Polyamine catabolism in relation to trypsin activation and apoptosis in experimental acute pancreatitis. ( Alhonen, L; Herzig, KH; Hyvönen, MT; Jin, HT; Lämsä, T; Nordback, I; Nordback, PH; Räty, S; Sand, J, 2011)
" Our experimental studies have shown that catabolism of spermidine and spermine to putrescine is associated with the development of pancreatitis."3.74A polyamine analog bismethylspermine ameliorates severe pancreatitis induced by intraductal infusion of taurodeoxycholate. ( Alhonen, L; Grigorenko, N; Herzig, KH; Hyvönen, MT; Jin, HT; Khomutov, AR; Lämsä, T; Nordback, I; Räty, S; Sand, J, 2008)
"We recently generated a transgenic rat model for acute pancreatitis, which was apparently caused by a massive depletion of pancreatic polyamines spermidine and spermine due to inducible activation of their catabolism (Alhonen, L."3.71A polyamine analogue prevents acute pancreatitis and restores early liver regeneration in transgenic rats with activated polyamine catabolism. ( Alhonen, L; Herzig, KH; Janne, J; Keinanen, T; Khomutov, AR; Rasanen, TL; Sinervirta, R; Suppola, S; Vepsalainen, J, 2002)
"Experimental pancreatitis is associated with activation of polyamine catabolism."1.37Association between remote organ injury and tissue polyamine homeostasis in acute experimental pancreatitis - treatment with a polyamine analogue bismethylspermine. ( Alhonen, L; Grigorenko, N; Hyvönen, MT; Jin, HT; Khomutov, AR; Lämsä, T; Nordback, I; Nordback, PH; Pörsti, I; Räty, S; Sand, J, 2011)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (62.50)29.6817
2010's3 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jin, HT3
Lämsä, T3
Hyvönen, MT3
Sand, J3
Räty, S3
Grigorenko, N3
Khomutov, AR3
Herzig, KH6
Alhonen, L8
Nordback, I3
Nordback, PH2
Uimari, A2
Merentie, M2
Sironen, R1
Pirnes-Karhu, S1
Peräniemi, S1
Pörsti, I1
Rasanen, TL1
Sinervirta, R3
Keinanen, T2
Suppola, S1
Vepsalainen, J2
Janne, J4
Pietilä, M1
Keinänen, TA1
Khomutov, A1
Parkkinen, JJ1

Other Studies

8 other studies available for spermine and Acute Edematous Pancreatitis

ArticleYear
A polyamine analog bismethylspermine ameliorates severe pancreatitis induced by intraductal infusion of taurodeoxycholate.
    Surgery, 2008, Volume: 144, Issue:1

    Topics: Animals; Bile Acids and Salts; Disease Models, Animal; Male; Pancreas; Pancreatitis; Polyamines; Rat

2008
Polyamine catabolism in relation to trypsin activation and apoptosis in experimental acute pancreatitis.
    Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2011, Volume: 11, Issue:2

    Topics: Acetyltransferases; Animals; Apoptosis; Disease Models, Animal; Enzyme Activation; Male; Oligopeptid

2011
Overexpression of spermidine/spermine N1-acetyltransferase or treatment with N1-N11-diethylnorspermine attenuates the severity of zinc-induced pancreatitis in mouse.
    Amino acids, 2012, Volume: 42, Issue:2-3

    Topics: Acetyltransferases; Animals; Immunohistochemistry; Mice; Mice, Transgenic; Pancreatitis; Severity of

2012
Association between remote organ injury and tissue polyamine homeostasis in acute experimental pancreatitis - treatment with a polyamine analogue bismethylspermine.
    Pharmacological reports : PR, 2011, Volume: 63, Issue:4

    Topics: Acetyltransferases; Animals; Creatinine; Disease Models, Animal; Dose-Response Relationship, Drug; K

2011
A polyamine analogue prevents acute pancreatitis and restores early liver regeneration in transgenic rats with activated polyamine catabolism.
    The Journal of biological chemistry, 2002, Oct-18, Volume: 277, Issue:42

    Topics: alpha-Amylases; Animals; Animals, Genetically Modified; Immunohistochemistry; Liver; Mice; Pancreati

2002
Acute pancreatitis induced by activation of the polyamine catabolism in gene-modified mice and rats overexpressing spermidine/spermine N1-acetyltransferase.
    Scandinavian journal of gastroenterology, 2005, Volume: 40, Issue:1

    Topics: Acute Disease; Animals; Biomarkers; Disease Models, Animal; Mice; Mice, Transgenic; Pancreatitis; Ra

2005
Oxidative stress and inflammation in the pathogenesis of activated polyamine catabolism-induced acute pancreatitis.
    Amino acids, 2007, Volume: 33, Issue:2

    Topics: Acetyltransferases; Acute Disease; Animals; Animals, Genetically Modified; Inflammation; Interleukin

2007
Activation of polyamine catabolism in transgenic rats induces acute pancreatitis.
    Proceedings of the National Academy of Sciences of the United States of America, 2000, Jul-18, Volume: 97, Issue:15

    Topics: Acetyltransferases; Acute Disease; Animals; Animals, Genetically Modified; Disease Models, Animal; E

2000