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spermine and Acute Brain Injuries

spermine has been researched along with Acute Brain Injuries in 9 studies

Research Excerpts

ExcerptRelevanceReference
" Here, we show that extracellular spermine, one of the endogenous polyamines, exacerbates ischemic neuronal injury through sensitization of ASIC1a channels to extracellular acidosis."7.77Extracellular spermine exacerbates ischemic neuronal injury through sensitization of ASIC1a channels to extracellular acidosis. ( Cao, H; Chu, XP; Duan, B; Hansen, J; Huang, Y; Simon, RP; Wang, YZ; Xiong, ZG; Xu, TL; Yang, T; Yu, Y; Zhu, MX, 2011)
" Here, we show that extracellular spermine, one of the endogenous polyamines, exacerbates ischemic neuronal injury through sensitization of ASIC1a channels to extracellular acidosis."3.77Extracellular spermine exacerbates ischemic neuronal injury through sensitization of ASIC1a channels to extracellular acidosis. ( Cao, H; Chu, XP; Duan, B; Hansen, J; Huang, Y; Simon, RP; Wang, YZ; Xiong, ZG; Xu, TL; Yang, T; Yu, Y; Zhu, MX, 2011)
"Kukoamine A (KuA) has the ability of anti-oxidative stress and anti-apoptosis in vitro."1.43Neuroprotective Effects of Kukoamine a against Radiation-induced Rat Brain Injury through Inhibition of Oxidative Stress and Neuronal Apoptosis. ( Cheng, Z; Ma, H; Meng, W; Wang, C; Zhang, Y; Zhao, Q, 2016)
"Spermine oxidase is a FAD-containing enzyme involved in polyamines catabolism, selectively oxidizing spermine to produce H2O2, spermidine, and 3-aminopropanal."1.39A New Transgenic Mouse Model for Studying the Neurotoxicity of Spermine Oxidase Dosage in the Response to Excitotoxic Injury. ( Amendola, R; Bellavia, G; Berger, J; Cavallucci, V; Cecconi, F; Cervelli, M; D'Amelio, M; Marcoli, M; Mariottini, P; Maura, G; Moreno, S; Nardacci, R; Piacentini, M, 2013)
"Spermine levels were normal at 6 h and decreased slightly at 24 h, but were normal again by 72 h post-injury."1.36Polyamine catabolism is enhanced after traumatic brain injury. ( Casero, RA; Huttinger, F; Morrison, R; Murray-Stewart, T; Strauss, KI; Zahedi, K, 2010)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (22.22)29.6817
2010's7 (77.78)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cervelli, M1
Bellavia, G1
D'Amelio, M1
Cavallucci, V1
Moreno, S1
Berger, J1
Nardacci, R1
Marcoli, M1
Maura, G1
Piacentini, M1
Amendola, R1
Cecconi, F1
Mariottini, P1
Hu, XL1
Gao, LY1
Niu, YX1
Tian, X1
Wang, J1
Meng, WH1
Zhang, Q1
Cui, C1
Han, L1
Zhao, QC1
Yan, H1
Hao, S1
Sun, X1
Zhang, D1
Gao, X1
Yu, Z1
Li, K1
Hang, CH1
Zhang, Y1
Cheng, Z1
Wang, C1
Ma, H1
Meng, W1
Zhao, Q1
Zahedi, K1
Huttinger, F1
Morrison, R1
Murray-Stewart, T1
Casero, RA1
Strauss, KI1
Duan, B1
Wang, YZ1
Yang, T1
Chu, XP1
Yu, Y1
Huang, Y1
Cao, H1
Hansen, J1
Simon, RP1
Zhu, MX1
Xiong, ZG1
Xu, TL1
Yamashita, S1
Hasuo, H1
Tokutomi, T1
Shigemori, M1
Akasu, T1
Seiler, N1
Adibhatla, RM1
Hatcher, JF1
Sailor, K1
Dempsey, RJ1

Reviews

1 review available for spermine and Acute Brain Injuries

ArticleYear
Oxidation of polyamines and brain injury.
    Neurochemical research, 2000, Volume: 25, Issue:4

    Topics: Amine Oxidase (Copper-Containing); Animals; Brain; Brain Injuries; Cattle; Enzyme Inhibitors; Humans

2000

Other Studies

8 other studies available for spermine and Acute Brain Injuries

ArticleYear
A New Transgenic Mouse Model for Studying the Neurotoxicity of Spermine Oxidase Dosage in the Response to Excitotoxic Injury.
    PloS one, 2013, Volume: 8, Issue:6

    Topics: Animals; Brain Injuries; Disease Models, Animal; Gene Dosage; HeLa Cells; Humans; Mice; Mice, Inbred

2013
Neuroprotection by Kukoamine A against oxidative stress may involve N-methyl-D-aspartate receptors.
    Biochimica et biophysica acta, 2015, Volume: 1850, Issue:2

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Brain Injuries; Calcium; Cell Line, Tumor; Humans; Hydroge

2015
Blockage of mitochondrial calcium uniporter prevents iron accumulation in a model of experimental subarachnoid hemorrhage.
    Biochemical and biophysical research communications, 2015, Jan-24, Volume: 456, Issue:4

    Topics: Animals; Apoptosis; Brain Injuries; Calcium Channels; Disease Models, Animal; Homeostasis; Iron; Mal

2015
Neuroprotective Effects of Kukoamine a against Radiation-induced Rat Brain Injury through Inhibition of Oxidative Stress and Neuronal Apoptosis.
    Neurochemical research, 2016, Volume: 41, Issue:10

    Topics: Animals; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Brain Injuries; Disease Models, Ani

2016
Polyamine catabolism is enhanced after traumatic brain injury.
    Journal of neurotrauma, 2010, Volume: 27, Issue:3

    Topics: Acetyltransferases; Animals; Biogenic Polyamines; Biomarkers; Brain; Brain Chemistry; Brain Injuries

2010
Extracellular spermine exacerbates ischemic neuronal injury through sensitization of ASIC1a channels to extracellular acidosis.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Feb-09, Volume: 31, Issue:6

    Topics: Acid Sensing Ion Channels; Acidosis; Amino Acid Transport System y+; Animals; Biophysics; Brain Inju

2011
Edaravone attenuates impairment of synaptic plasticity in granule cell layer of the dentate gyrus following traumatic brain injury.
    The Kurume medical journal, 2011, Volume: 58, Issue:2

    Topics: Animals; Antipyrine; Brain Injuries; Dentate Gyrus; Edaravone; Electric Stimulation; Excitatory Post

2011
Polyamines and central nervous system injury: spermine and spermidine decrease following transient focal cerebral ischemia in spontaneously hypertensive rats.
    Brain research, 2002, May-31, Volume: 938, Issue:1-2

    Topics: Animals; Brain; Brain Injuries; Gerbillinae; Ischemic Attack, Transient; Putrescine; Rats; Rats, Inb

2002