spermidine has been researched along with Reperfusion Injury in 10 studies
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Kidney ischemia and reperfusion injury (IRI) is associated with a high mortality rate, which is attributed to tubular oxidative stress and necrosis; however, an effective approach to limit IRI remains elusive." | 5.46 | Spermidine rescues proximal tubular cells from oxidative stress and necrosis after ischemic acute kidney injury. ( Kim, J, 2017) |
| " This study investigated the impact of polyamines (spermidine and spermine) on ischemia/reperfusion injury (IRI) and liver regeneration." | 3.83 | Oral administration of polyamines ameliorates liver ischemia/reperfusion injury and promotes liver regeneration in rats. ( Fujimoto, Y; Iida, T; Kaido, T; Kasahara, N; Masano, Y; Okumura, S; Teratani, T; Tsuruyama, T; Uemoto, S; Uemura, T; Yagi, S; Zhao, X, 2016) |
| "Kidney ischemia and reperfusion injury (IRI) is associated with a high mortality rate, which is attributed to tubular oxidative stress and necrosis; however, an effective approach to limit IRI remains elusive." | 1.46 | Spermidine rescues proximal tubular cells from oxidative stress and necrosis after ischemic acute kidney injury. ( Kim, J, 2017) |
| "Acute kidney injury is associated with the activation of NMDA receptors, as well as significant oxidative stress." | 1.39 | Effect of modulating the allosteric sites of N-methyl-D-aspartate receptors in ischemia-reperfusion induced acute kidney injury. ( Arora, S; Kaur, T; Pundir, M; Singh, AP; Singh, R, 2013) |
| "Thymoquinone treatment caused the reversal of I/R-induced changes in MDA as well as GST and SOD activity." | 1.37 | Effect of thymoquinone on hepatorenal dysfunction and alteration of CYP3A1 and spermidine/spermine N-1-acetyl-transferase gene expression induced by renal ischaemia-reperfusion in rats. ( Awad, AS; Kamel, R; Sherief, MA, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 6 (60.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sieckmann, T | 1 |
| Schley, G | 1 |
| Ögel, N | 1 |
| Kelterborn, S | 1 |
| Boivin, FJ | 1 |
| Fähling, M | 1 |
| Ashraf, MI | 1 |
| Reichel, M | 1 |
| Vigolo, E | 1 |
| Hartner, A | 1 |
| Lichtenberger, FB | 1 |
| Breiderhoff, T | 1 |
| Knauf, F | 1 |
| Rosenberger, C | 1 |
| Aigner, F | 1 |
| Schmidt-Ott, K | 1 |
| Scholz, H | 1 |
| Kirschner, KM | 1 |
| Liu, H | 1 |
| Dong, J | 1 |
| Song, S | 1 |
| Zhao, Y | 1 |
| Wang, J | 1 |
| Fu, Z | 1 |
| Yang, J | 1 |
| Yang, Y | 1 |
| Chen, S | 1 |
| Zhang, Y | 1 |
| Lin, X | 1 |
| Song, Y | 1 |
| Xue, Z | 1 |
| Qian, H | 1 |
| Wang, S | 1 |
| Wan, G | 1 |
| Zheng, X | 1 |
| Zhang, L | 1 |
| Kim, J | 1 |
| Pundir, M | 1 |
| Arora, S | 1 |
| Kaur, T | 1 |
| Singh, R | 1 |
| Singh, AP | 1 |
| Okumura, S | 1 |
| Teratani, T | 1 |
| Fujimoto, Y | 1 |
| Zhao, X | 1 |
| Tsuruyama, T | 1 |
| Masano, Y | 1 |
| Kasahara, N | 1 |
| Iida, T | 1 |
| Yagi, S | 1 |
| Uemura, T | 1 |
| Kaido, T | 1 |
| Uemoto, S | 1 |
| Awad, AS | 1 |
| Kamel, R | 1 |
| Sherief, MA | 1 |
| Diler, AS | 1 |
| Ziylan, YZ | 1 |
| Uzum, G | 1 |
| Lefauconnier, JM | 1 |
| Seylaz, J | 1 |
| Pinard, E | 1 |
| Reid, KM | 1 |
| Tsung, A | 1 |
| Kaizu, T | 1 |
| Jeyabalan, G | 1 |
| Ikeda, A | 1 |
| Shao, L | 1 |
| Wu, G | 1 |
| Murase, N | 1 |
| Geller, DA | 1 |
| Rao, AM | 1 |
| Hatcher, JF | 1 |
| Doğan, A | 1 |
| Dempsey, RJ | 1 |
10 other studies available for spermidine and Reperfusion Injury
| Article | Year |
|---|---|
Strikingly conserved gene expression changes of polyamine regulating enzymes among various forms of acute and chronic kidney injury.
Topics: Acetyltransferases; Amine Oxidase (Copper-Containing); Animals; Gene Expression; Humans; Kidney; Mic | 2023 |
Spermidine ameliorates liver ischaemia-reperfusion injury through the regulation of autophagy by the AMPK-mTOR-ULK1 signalling pathway.
Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Autophagy-Related Protein-1 Homolog; Liver; Male; | 2019 |
Induction of autophagy by spermidine is neuroprotective via inhibition of caspase 3-mediated Beclin 1 cleavage.
Topics: Animals; Autophagy; Beclin-1; Caspase 3; Cerebral Cortex; Hippocampus; Neurons; Neuroprotective Agen | 2017 |
Spermidine rescues proximal tubular cells from oxidative stress and necrosis after ischemic acute kidney injury.
Topics: Animals; Antioxidants; Cell Culture Techniques; Disease Models, Animal; Gene Knockdown Techniques; H | 2017 |
Effect of modulating the allosteric sites of N-methyl-D-aspartate receptors in ischemia-reperfusion induced acute kidney injury.
Topics: Acute Kidney Injury; Allosteric Site; Animals; Catalase; Glutamic Acid; Glutathione; Ketamine; Kynur | 2013 |
Oral administration of polyamines ameliorates liver ischemia/reperfusion injury and promotes liver regeneration in rats.
Topics: Administration, Oral; Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Cell Pr | 2016 |
Effect of thymoquinone on hepatorenal dysfunction and alteration of CYP3A1 and spermidine/spermine N-1-acetyl-transferase gene expression induced by renal ischaemia-reperfusion in rats.
Topics: Acetyltransferases; Alanine Transaminase; Animals; Antioxidants; Benzoquinones; Creatinine; Cytochro | 2011 |
Passage of spermidine across the blood-brain barrier in short recirculation periods following global cerebral ischemia: effects of mild hyperthermia.
Topics: Aminoisobutyric Acids; Animals; Blood-Brain Barrier; Brain; Brain Ischemia; Hypothermia, Induced; Ma | 2002 |
Liver I/R injury is improved by the arginase inhibitor, N(omega)-hydroxy-nor-L-arginine (nor-NOHA).
Topics: Alanine Transaminase; Animals; Arginase; Arginine; Aspartate Aminotransferases; Biogenic Polyamines; | 2007 |
Elevated N1-acetylspermidine levels in gerbil and rat brains after CNS injury.
Topics: Animals; Arterial Occlusive Diseases; Blood-Brain Barrier; Brain; Brain Injuries; Cerebral Arteries; | 2000 |