spermidine has been researched along with Pulmonary Fibrosis in 3 studies
Pulmonary Fibrosis: A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Spermidine is an endogenous biological polyamine that plays various longevity-extending roles and exerts antioxidative, antiaging, and cell growth-promoting effects." | 1.56 | Spermidine attenuates bleomycin-induced lung fibrosis by inducing autophagy and inhibiting endoplasmic reticulum stress (ERS)-induced cell death in mice. ( Baek, AR; Chin, SS; Hong, J; Jang, AS; Kim, DJ; Park, SW; Song, KS, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Baek, AR | 1 |
| Hong, J | 1 |
| Song, KS | 1 |
| Jang, AS | 1 |
| Kim, DJ | 1 |
| Chin, SS | 1 |
| Park, SW | 1 |
| Cho, IH | 1 |
| Choi, YJ | 1 |
| Gong, JH | 1 |
| Shin, D | 1 |
| Kang, MK | 1 |
| Kang, YH | 1 |
| Raisfeld, IH | 1 |
3 other studies available for spermidine and Pulmonary Fibrosis
| Article | Year |
|---|---|
Spermidine attenuates bleomycin-induced lung fibrosis by inducing autophagy and inhibiting endoplasmic reticulum stress (ERS)-induced cell death in mice.
Topics: Animals; Autophagy; Biomarkers; Bleomycin; Cell Death; Cellular Senescence; Cytokines; Disease Model | 2020 |
Astragalin inhibits autophagy-associated airway epithelial fibrosis.
Topics: Airway Remodeling; Animals; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Cdh1 Proteins; Cell | 2015 |
Role of terminal substituents in the pulmonary toxicity of bleomycins.
Topics: Animals; Bleomycin; Lung; Lung Diseases; Male; Metaplasia; Mice; Pulmonary Fibrosis; Spermidine; Str | 1981 |