Page last updated: 2024-10-20

spermidine and Pregnancy

spermidine has been researched along with Pregnancy in 101 studies

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"N-ethyl-N-nitrosourea-induced rat gliomas showed a stimulation of cytosolic spermidine N-acetyltransferase activity compared with normal brain, with an increased formation of N1 and N8-acetylspermidine, suggesting the activation of two enzymes acetylating the polyamine in N1 and N8 position, respectively."7.69Spermidine acetylation in N1 and N8 position in rat brain and in N-ethyl-N-nitrosourea-induced gliomas. ( Broglia, E; Perin, A; Sessa, A; Terreni, MR, 1994)
"Spermidine (SPD) has shown to improve cognition, but its effect on the cognitive function of IUH offspring remains unknown."5.62Impact of intrauterine hypoxia on adolescent and adult cognitive function in rat offspring: sexual differences and the effects of spermidine intervention. ( Ai, J; Jin, Z; Li, LX; Li, TT; Mao, M; Wang, YR; Yang, L; Zhao, YJ, 2021)
"We aimed to evaluate the levels of Spermidine, Syndecan 1, and Glypican 3 (GPC3) in the follicle fluid of women with diminished ovarian reserve (DOR) and to examine the relationship of these markers with the number of embryos and clinical pregnancy."4.31Evaluation of Intrafollicular Syndecan 1, Glypican 3, and Spermidine Levels in Women with Diminished Ovarian Reserve. ( Cevik, O; Gokce, S; Herkiloglu, D; Turan, V, 2023)
"N-ethyl-N-nitrosourea-induced rat gliomas showed a stimulation of cytosolic spermidine N-acetyltransferase activity compared with normal brain, with an increased formation of N1 and N8-acetylspermidine, suggesting the activation of two enzymes acetylating the polyamine in N1 and N8 position, respectively."3.69Spermidine acetylation in N1 and N8 position in rat brain and in N-ethyl-N-nitrosourea-induced gliomas. ( Broglia, E; Perin, A; Sessa, A; Terreni, MR, 1994)
"Our purpose was to test the prediction that spermine levels in IVF culture supernatants measure by rapid ELISA assay correlate with subsequent success or failure to establish a pregnancy."3.69High levels of spermine in IVF medium as a negative predictor of subsequent success of embryo transfer. ( Clark, DA; Craft, I; Delcros, JG, 1996)
"It has been suggested that the induction of ornithine decarboxylase (ODC) activity during pregnancy might contribute to the low ureagenic flux that enables the pregnant mother to spare nitrogen and support growth."3.68Ornithine decarboxylase activity and urea in liver of late-pregnant rats. Effect of streptozotocin-induced diabetes. ( Pastor-Anglada, M; Poveda, B; Soler, C; Soley, M, 1993)
" The results indicate that there are 2 significant differences between the choriocarcinoma and the mole: 1) the choriocarcinoma is characterized by increased polyamine and nucleic acid levels, 2) tissues differ in their putrescine:spermidine and spermidine:spermine ratios."3.67Polyamines and nucleic acids in gestational trophoblastic tumors. ( Cecco, L; Cerra, M; Pagnano, AM; Paladini, A; Pasquinelli, R; Romano, M, 1985)
" At the 12th day of pregnancy, a decrease of putrescine in the liver of the mother and marked increases in putrescine, cadaverine and spermidine in embryos were observed."3.67Polyamines and diamine oxidase activity in maternal, embryonal, and fetal tissues of rat after chronic ethanol consumption. ( Desiderio, MA; Perin, A; Sessa, A, 1987)
"Urinary total polyamines; putrescine, spermidine and cadaverine, levels were determined in the estrous cycle and during the pregnancy in female Wistar rats."3.67[Urinary total polyamines levels in estrous cycle and during pregnancy in female rats]. ( Ohsawa, N; Torii, R, 1988)
" Spermidine and spermine concentrations in fetal red blood cells decreased markedly with the progress of pregnancy."3.67Concentrations of polyamines in umbilical blood. ( Eguchi, K; Hiramatsu, Y; Sekiba, K, 1985)
"The nature of the side effects produced by the antimalarials and a common moiety present in these drugs (spermidine) links the polyamines to both schizophrenia and depression."3.67The side effects of antimalarial drugs indicates a polyamine involvement in both schizophrenia and depression. ( Andrews, RC, 1985)
"The in vivo metabolism of 14C-putrescine injected to rats before, during and after pregnancy was studied."3.66Metabolism of putrescine in the pregnant rat. ( Andersson, AC; Henningsson, S, 1981)
"The urinary excretion of the diamines histamine, methylhistamine, putrescine and cadaverine and the polyamines spermidine and spermine was studied in rats which on the 19th day of pregnancy were subjected to various ectomizing operations."3.66On the biogenesis of diamines and polyamines in the pregnant rat. ( Andersson, AC; Henningsson, S, 1981)
" Spermidine and spermine continued to increase with pregnancy and retained a high level during 24-35 weeks of gestation, then decreased at term; putrescine, however, kept the low nonpregnant level during pregnancy and puerperium."3.66Alterations of red blood cells' polyamines during pregnancy and neonatal period. ( Eguchi, K; Hayase, R; Hiramatsu, Y; Sekiba, K; Yonezawa, M, 1981)
" Putrescine was not an inhibitor in the presence of foetal calf serum but became so in the presence of human pregnancy serum, possibly due to the action of diamine oxidase."3.66Inhibition of lymphocyte proliferation by polyamines requires ruminant-plasma polyamine oxidase. ( Allen, JC; Gaugas, JM; Hussain, JI; Smith, CJ; Thomas, JM, 1979)
"Spermidine concentration in rabbit mammary gland was estimated during pregnancy, lactation and after the induction of milk synthesis by prolactin and glucocorticoids in vivo and in vitro."3.66Role of spermidine in casein gene expression in the rabbit. ( Delouis, C; Devinoy, E; Houdebine, LM, 1978)
" The urinary excretion of histamine, methylhistamine, putrescine, cadaverine, spermidine and spermine was examined before, during and after pregnancy in rats."3.66Increased formation of diamines and polyamines in the pregnant rat. ( Andersson, AC; Henningsson, S; Rosengren, E, 1978)
"The pregnancy of the rat brings about profound changes of the accumulation, biosynthesis and biodegradtion of the polyamines putrescine, spermidine and spermine in the reproductive tissues."3.65The synthesis and accumulation of polyamines in reproductive organs of the rat during pregnancy. ( Guha, SK; Jänne, J, 1976)
" Transfer RNA of maternal mouse organs and total embryo at 13 and 17 days of pregnancy was acylated in vitro with [3H] or [14C] histidine and examined by reversed-phase plaskon chromatography."3.65Mouse histidyl-tRNAs during pregnancy. Differentiation of activity profiles within and between organs. ( de León, V; Sirlin, JL; Yang, WK, 1975)
"Spermidine (SPD) has shown to improve cognition, but its effect on the cognitive function of IUH offspring remains unknown."1.62Impact of intrauterine hypoxia on adolescent and adult cognitive function in rat offspring: sexual differences and the effects of spermidine intervention. ( Ai, J; Jin, Z; Li, LX; Li, TT; Mao, M; Wang, YR; Yang, L; Zhao, YJ, 2021)
"Putrescine was the least concentrated of these substances in both milk types."1.42Polyamine profile in ovine and caprine colostrum and milk. ( Alichanidis, E; Galitsopoulou, A; Menexes, G; Michaelidou, AM, 2015)
"Obesity is associated with risks for mother and infant, and the mothers' dietary habits influence breast milk composition."1.39Lower polyamine levels in breast milk of obese mothers compared to mothers with normal body weight. ( Ali, MA; Palme-Kilander, C; Strandvik, B; Yngve, A, 2013)
"Spermidine and histamine were competitive inhibitors of putrescine with an inhibition constant of 1."1.27Diamine oxidase activity in human decidua and endometrium. ( Gurpide, E; Holinka, CF, 1984)
"Only 29% of the patients with breast carcinoma had elevated levels of spermidine compared to normal female subjects."1.26Plasma spermidine concentrations in patients with tumours of the breast or prostate or testis. ( Blamey, RW; Chaisiri, P; Griffiths, K; Harper, ME; Peeling, WB, 1980)
"Spermine levels were not decreased and in some cases were actually increased during the course of alpha-difluoromethylornithine administration; assessment of total organ content of spermine or total polyamines per organ (putrescine + spermidine + spermine) indicated that the tissues were still actively increasing their net polyamine content despite continued inhibition of ODC."1.26Ornithine decarboxylase and polyamines in tissues of the neonatal rat: effects of alpha-difluoromethylornithine, a specific, irreversible inhibitor of ornithine decarboxylase. ( Barnes, GA; Bartolome, J; Lerea, L; Seidler, FJ; Slotkin, TA; Trepanier, PA; Weigel, SJ; Whitmore, WL, 1982)
"The putrescine conjugate was purified to homogeneity by column chromatography on Biogels P10 and P6 followed by ion-exchange chromatography on DEAE-Sephadex A-25."1.26Isolation and characterization of a polyamine-peptide conjugate from human amniotic fluid. ( Chan, WY; Rennert, OM; Seale, TW; Shukla, JB, 1979)
"Putrescine and spermine were elevated in the urine of women with normal pregnancies."1.26Polyamines in amniotic fluid, plasma, and urine during normal pregnancy. ( Campbell, JL; Christian, CD; Giles, HR; Russell, DH, 1978)

Research

Studies (101)

TimeframeStudies, this research(%)All Research%
pre-199069 (68.32)18.7374
1990's17 (16.83)18.2507
2000's6 (5.94)29.6817
2010's7 (6.93)24.3611
2020's2 (1.98)2.80

Authors

AuthorsStudies
Cai, J1
Soloway, AH1
Barth, RF1
Adams, DM1
Hariharan, JR1
Wyzlic, IM1
Radcliffe, K1
Gokce, S1
Herkiloglu, D1
Cevik, O1
Turan, V1
Mao, M1
Yang, L1
Jin, Z1
Li, LX1
Wang, YR1
Li, TT1
Zhao, YJ1
Ai, J1
Ali, MA1
Strandvik, B1
Palme-Kilander, C1
Yngve, A1
Kämpfer, P1
Glaeser, S1
Busse, HJ1
Eisenberg, T1
Scholz, H1
Wang, X1
Ying, W1
Dunlap, KA1
Lin, G1
Satterfield, MC1
Burghardt, RC1
Wu, G2
Bazer, FW2
Galitsopoulou, A1
Michaelidou, AM1
Menexes, G1
Alichanidis, E1
Basystyi, O1
Lefèvre, PL1
Palin, MF1
Murphy, BD1
Plaza-Zamora, J1
Sabater-Molina, M1
Rodríguez-Palmero, M1
Rivero, M1
Bosch, V1
Nadal, JM1
Zamora, S1
Larqué, E1
Honse, Y1
Randall, PK1
Leslie, SW1
Hu, J1
Johnson, GA1
Spencer, TE1
Ravikumar, N1
Houlihan, DD1
Morrison, JJ1
Hyvönen, MT1
Uimari, A1
Keinänen, TA1
Heikkinen, S1
Pellinen, R1
Wahlfors, T1
Korhonen, A1
Närvänen, A1
Wahlfors, J1
Alhonen, L1
Jänne, J2
Takemoto, T1
Nagamatsu, Y1
Oka, T8
Chaisiri, P1
Harper, ME1
Blamey, RW1
Peeling, WB1
Griffiths, K1
Holinka, CF1
Gurpide, E1
Matusik, RJ1
Rosen, JM1
Moore, JJ1
Cardaman, RC1
Lundgren, DW1
Russell, DH4
Slotkin, TA3
Bartolome, J2
Persons, D1
Whitmore, WL3
Tadolini, B1
Cabrini, L1
Sechi, AM1
Muskiet, FA1
van den Berg, GA1
Kingma, AW1
Fremouw-Ottevangers, DC1
Halie, MR1
Perry, JW4
Terada, N1
Fozard, JR1
Prakash, NJ1
Grove, J1
Gahl, WA1
Vale, AM1
Pitot, HC1
Seidler, FJ2
Trepanier, PA1
Lerea, L1
Barnes, GA1
Weigel, SJ2
Andersson, AC3
Henningsson, S3
Rennert, OM2
Chan, WY2
Griesmann, G1
Hiramatsu, Y2
Eguchi, K2
Yonezawa, M1
Hayase, R1
Sekiba, K2
Kleczkowska, D1
Niedbalski, W1
Zwierzchowski, L1
Vanella, A1
Di Silvestro, I1
D'Urso, G1
Avitabile, M1
Grasso, M1
Rapisarda, A1
Pinturo, R1
Roh, SG1
Baik, MG1
Woo, JH1
Choi, YJ1
Sooranna, SR1
Das, I1
Packianathan, S1
Cain, CD1
Longo, LD1
Capano, G1
Bloch, KJ1
Schiffrin, EJ1
Dascoli, JA1
Israel, EJ1
Harmatz, PR1
Sessa, A3
Broglia, E1
Terreni, MR1
Perin, A3
Brock, M1
Henley, CM1
Manev, RM1
Gabellini, N1
Manev, H1
Poveda, B1
Soler, C1
Soley, M1
Pastor-Anglada, M1
Sparapani, M1
Virgili, M1
Caprini, M1
Facchinetti, F1
Ciani, E1
Contestabile, A1
Clark, DA2
Delcros, JG1
Craft, I1
Uzüm, G1
Diler, AS1
Ziylan, Z1
Rillema, JA2
Collins, S1
Williams, CH1
Rodriguez-Sallaberry, C1
Simmen, FA1
Simmen, RC1
Kremzner, LT1
Sturman, JA3
Bolander, FF1
Topper, YJ1
Allen, JC1
Smith, CJ1
Hussain, JI1
Thomas, JM1
Gaugas, JM1
D'Anna, M1
Seale, TW1
Shukla, JB1
Heby, O1
Andersson, G1
Porta, R1
Servillo, L1
Abbruzzese, A1
Della Pietra, G1
Chomczyński, P1
Giles, HR1
Christian, CD1
Campbell, JL1
Houdebine, LM1
Devinoy, E1
Delouis, C1
Rosengren, E1
Gaull, GE2
Guha, SK1
McAnulty, PA1
Yusuf, HK1
Dickerson, JW1
Hey, EN1
Waterlow, JC1
Peters, AR1
Mepham, TB1
Thakur, AN1
Sheth, AR2
Purandare, TV1
Munshi, SR1
Rao, SS2
Marton, LJ1
Lee, PL1
de León, V1
Yang, WK1
Sirlin, JL1
Fujita, K1
Nagatsu, T1
Maruta, K3
Ito, M1
Senba, H1
Kano, K1
Piggott, MA1
Perry, EK1
Perry, RH1
Court, JA1
Elliott, J1
Fowden, AL1
Callingham, BA1
Sharman, DF1
Silver, M1
Porat, O1
Young, AJ1
Schmotzer, WB1
Swanson, LV1
Waters, SB1
Mandella, RD1
Piacentini, M1
Sartori, C1
Beninati, S1
Bargagli, AM1
Cerù-Argento, MP1
Bartolome, JV1
Bartolome, MB1
Daltner, LA1
Evans, CJ1
Barchas, JD1
Kuhn, CM1
Schanberg, SM1
Leiderman, LJ1
Criss, WE1
Romano, M1
Cecco, L1
Cerra, M1
Pasquinelli, R1
Pagnano, AM1
Paladini, A1
Ferrante, A1
Maxwell, GM1
Rencis, VO1
Allison, AC1
Morgan, DM1
Desiderio, MA1
Navaratnam, N1
Ward, S1
Fisher, C1
Kuhn, NJ1
Keen, JN1
Findlay, JB1
Osa, T2
Torii, R1
Ohsawa, N1
Ientile, R1
Russo, P1
Macaione, S1
Mizoguchi, Y1
Grillo, MA1
Saito, H1
Casti, A1
Bacciottini, F1
Orlandini, G1
Reali, N1
Zannino, L1
Bernasconi, S1
Andrews, RC1
McVicker, TA2
Gunaga, CK1
Gunaga, KP1
Purandare, MC1
Hernandez, O1
Ballesteros, LM1
Mendez, D1
Rosado, A1
Sanguansermsri, J1
György, P1
Zilliken, F1
Levy, CC1
Schimpff, SC1
Hawk, IA1
Russel, DH1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of an Immediate-postpartum Support by IBCLC to Women With Obesity, on Breastfeeding Performance: A Randomized Trial.[NCT02756169]261 participants (Actual)Interventional2016-07-14Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for spermidine and Pregnancy

ArticleYear
Polyamines on the reproductive landscape.
    Endocrine reviews, 2011, Volume: 32, Issue:5

    Topics: Animals; Embryo Implantation; Embryonic Development; Female; Fertilization; Gonadal Steroid Hormones

2011
Clinical relevance of polyamines.
    Critical reviews in clinical laboratory sciences, 1983, Volume: 18, Issue:3

    Topics: Animals; Cadaverine; Cystic Fibrosis; Diamines; Female; Growth Disorders; Humans; Kidney Failure, Ch

1983
Ethanol and polyamine metabolism: physiologic and pathologic implications: a review.
    Alcoholism, clinical and experimental research, 1997, Volume: 21, Issue:2

    Topics: Alcoholic Intoxication; Alcoholism; Animals; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Hist

1997
Metabolism and function of polyamines.
    The International journal of biochemistry, 1985, Volume: 17, Issue:9

    Topics: Acetyltransferases; Animals; Cell Differentiation; DNA Replication; Female; Mammary Glands, Animal;

1985

Other Studies

97 other studies available for spermidine and Pregnancy

ArticleYear
Boron-containing polyamines as DNA targeting agents for neutron capture therapy of brain tumors: synthesis and biological evaluation.
    Journal of medicinal chemistry, 1997, Nov-21, Volume: 40, Issue:24

    Topics: Animals; Antineoplastic Agents; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; DNA

1997
Evaluation of Intrafollicular Syndecan 1, Glypican 3, and Spermidine Levels in Women with Diminished Ovarian Reserve.
    Reproductive sciences (Thousand Oaks, Calif.), 2023, Volume: 30, Issue:2

    Topics: Adult; Embryo Transfer; Female; Fertilization in Vitro; Glypicans; Humans; Infertility, Female; Midd

2023
Impact of intrauterine hypoxia on adolescent and adult cognitive function in rat offspring: sexual differences and the effects of spermidine intervention.
    Acta pharmacologica Sinica, 2021, Volume: 42, Issue:3

    Topics: Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopep

2021
Lower polyamine levels in breast milk of obese mothers compared to mothers with normal body weight.
    Journal of human nutrition and dietetics : the official journal of the British Dietetic Association, 2013, Volume: 26 Suppl 1

    Topics: Adult; Body Mass Index; Breast Feeding; Feeding Behavior; Female; Guidelines as Topic; Humans; Lacta

2013
Falsochrobactrum ovis gen. nov., sp. nov., isolated from a sheep.
    International journal of systematic and evolutionary microbiology, 2013, Volume: 63, Issue:Pt 10

    Topics: Animals; Bacterial Typing Techniques; Base Composition; DNA, Bacterial; Fatty Acids; Female; Genes,

2013
Arginine decarboxylase and agmatinase: an alternative pathway for de novo biosynthesis of polyamines for development of mammalian conceptuses.
    Biology of reproduction, 2014, Volume: 90, Issue:4

    Topics: Agmatine; Animals; Carboxy-Lyases; Cationic Amino Acid Transporter 1; Citrulline; Embryo Implantatio

2014
Polyamine profile in ovine and caprine colostrum and milk.
    Food chemistry, 2015, Apr-15, Volume: 173

    Topics: Animals; Biogenic Polyamines; Chromatography, High Pressure Liquid; Colostrum; Female; Goats; Milk;

2015
[POLYAMINE CONCENTRATION IN ERYTHROCYTES IN THE BLOOD OF PREGNANT WOMEN WITH INTRAUTERINE GROWTH RETARDATION].
    Georgian medical news, 2016, Issue:261

    Topics: Adult; Case-Control Studies; Erythrocytes; Female; Fetal Growth Retardation; Humans; Polyamines; Pre

2016
Polyamines in human breast milk for preterm and term infants.
    The British journal of nutrition, 2013, Aug-28, Volume: 110, Issue:3

    Topics: Breast Feeding; Female; Humans; Infant, Newborn; Infant, Premature; Lactation; Milk, Human; Polyamin

2013
Prenatal ethanol exposure modifies [3H]MK-801 binding to NMDA receptors: spermidine and ifenprodil.
    Alcoholism, clinical and experimental research, 2003, Volume: 27, Issue:12

    Topics: Alternative Splicing; Animals; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Dru

2003
Polyamine synthesis from proline in the developing porcine placenta.
    Biology of reproduction, 2005, Volume: 72, Issue:4

    Topics: 1-Pyrroline-5-Carboxylate Dehydrogenase; Amniotic Fluid; Animals; Arginase; Carbon Radioisotopes; Fe

2005
Effects of polyamines on human umbilical artery tone in vitro.
    Journal of the Society for Gynecologic Investigation, 2004, Volume: 11, Issue:8

    Topics: Adult; Female; Gestational Age; Humans; In Vitro Techniques; Polyamines; Pregnancy; Spermidine; Sper

2004
Polyamine-regulated unproductive splicing and translation of spermidine/spermine N1-acetyltransferase.
    RNA (New York, N.Y.), 2006, Volume: 12, Issue:8

    Topics: Acetyltransferases; Alternative Splicing; Animals; Exons; Female; Gene Expression Regulation, Enzymo

2006
The study of spermidine-stimulated polypeptide synthesis in cell-free translation of mRNA from lactating mouse mammary gland.
    Biochimica et biophysica acta, 1983, May-20, Volume: 740, Issue:1

    Topics: Animals; Cell-Free System; Female; Lactation; Mammary Glands, Animal; Mice; Mice, Inbred C3H; Peptid

1983
Plasma spermidine concentrations in patients with tumours of the breast or prostate or testis.
    Clinica chimica acta; international journal of clinical chemistry, 1980, Jul-01, Volume: 104, Issue:3

    Topics: Adult; Aged; Breast Neoplasms; Female; Humans; Male; Menopause; Middle Aged; Pregnancy; Prostatic Hy

1980
Diamine oxidase activity in human decidua and endometrium.
    American journal of obstetrics and gynecology, 1984, Oct-15, Volume: 150, Issue:4

    Topics: Amine Oxidase (Copper-Containing); Culture Media; Decidua; Endometrium; Estradiol; Female; Histamine

1984
Prolactin regulation of casein gene expression: possible mediators.
    Endocrinology, 1980, Volume: 106, Issue:1

    Topics: Animals; Bucladesine; Caseins; Cyclic AMP; Cyclic GMP; Dibutyryl Cyclic GMP; Female; Kinetics; Mamma

1980
Spermine-enhanced protein phosphorylation in human placenta.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1984, Volume: 176, Issue:3

    Topics: Adenosine Triphosphate; Cyclic AMP; Dose-Response Relationship, Drug; Female; Humans; Molecular Weig

1984
Polyamines in brain and heart of the neonatal rat: effects of inhibitors of ornithine decarboxylase and spermidine synthase.
    Life sciences, 1984, Sep-03, Volume: 35, Issue:10

    Topics: Animals; Animals, Newborn; Brain; Cyclohexylamines; Dose-Response Relationship, Drug; Eflornithine;

1984
Representative applications of heparin-sepharose in the removal of polyamines from biological materials.
    Applied biochemistry and biotechnology, 1984, Volume: 9, Issue:2

    Topics: Animals; Cattle; DNA; Female; Male; Membranes; Methods; Mitochondria, Heart; Polyamines; Pregnancy;

1984
Total polyamines and their non-alpha-amino acid metabolites simultaneously determined in urine by capillary gas chromatography, with nitrogen-phosphorus detector; and some clinical applications.
    Clinical chemistry, 1984, Volume: 30, Issue:5

    Topics: Adolescent; Adult; Aged; Amino Acids, Diamino; Cadaverine; Child; Child, Preschool; Chromatography,

1984
The regulatory function of spermidine in hormonal control of the development of mouse mammary gland in culture.
    Federation proceedings, 1982, Volume: 41, Issue:14

    Topics: Adenosylmethionine Decarboxylase; Animals; Caseins; Cell Differentiation; Culture Techniques; Female

1982
Ovarian function in the rat following irreversible inhibition of L-ornithine decarboxylase.
    Life sciences, 1980, Dec-08, Volume: 27, Issue:23

    Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Eflornithine; Estrus; Female; Mitoguazone

1980
Spermidine oxidase in human pregnancy serum. Probable identity with diamine oxidase.
    The Biochemical journal, 1982, Jan-01, Volume: 201, Issue:1

    Topics: Amine Oxidase (Copper-Containing); Female; Humans; Hydrogen-Ion Concentration; Kinetics; Oxidoreduct

1982
Ornithine decarboxylase and polyamines in tissues of the neonatal rat: effects of alpha-difluoromethylornithine, a specific, irreversible inhibitor of ornithine decarboxylase.
    The Journal of pharmacology and experimental therapeutics, 1982, Volume: 222, Issue:3

    Topics: Animals; Animals, Newborn; Brain; Carboxy-Lyases; Eflornithine; Female; Heart; Kidney; Myocardium; O

1982
Metabolism of putrescine in the pregnant rat.
    Acta physiologica Scandinavica, 1981, Volume: 113, Issue:4

    Topics: Animals; Carbon Dioxide; Female; Pregnancy; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Sper

1981
Toxic effects of maternal methadone administration on cardiac development in the neonatal rat: potential participation of altered polyamine levels in growth impairment.
    Toxicology letters, 1982, Volume: 14, Issue:3-4

    Topics: Aging; Animals; Animals, Newborn; Female; Heart; Methadone; Myocardium; Ornithine Decarboxylase; Pol

1982
On the biogenesis of diamines and polyamines in the pregnant rat.
    Acta endocrinologica, 1981, Volume: 98, Issue:3

    Topics: Animals; Cadaverine; Castration; Diamines; Female; Fetus; Histamine; Hysterectomy; Methylhistamines;

1981
Polyamine-peptide conjugates: proposed functions.
    Physiological chemistry and physics, 1980, Volume: 12, Issue:5

    Topics: Amino Acids; Amniotic Fluid; Female; Humans; Polyamines; Pregnancy; Proteins; Putrescine; Spermidine

1980
Alterations of red blood cells' polyamines during pregnancy and neonatal period.
    Biology of the neonate, 1981, Volume: 40, Issue:3-4

    Topics: Cadaverine; Chromatography, High Pressure Liquid; Erythrocytes; Female; Fetal Blood; Humans; Infant,

1981
Effects of spermidine and spermine on DNA synthesis in isolated nuclei and on the activity of DNA polymerases alpha and beta from the mammary gland of pregnant rabbit.
    Acta biochimica Polonica, 1981, Volume: 28, Issue:3-4

    Topics: Animals; Cell Nucleus; DNA; DNA Polymerase I; DNA Polymerase II; Female; Mammary Glands, Animal; Pre

1981
Polyamine levels in rat placenta during pregnancy.
    Acta Europaea fertilitatis, 1980, Volume: 11, Issue:1

    Topics: Animals; Female; Placenta; Pregnancy; Pregnancy, Animal; Rats; Spermidine; Spermine; Time Factors

1980
Non-hormonal factors on differentiation of bovine mammary cells.
    In vitro cellular & developmental biology. Animal, 1994, Volume: 30A, Issue:5

    Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Amino Acids; Animals; Azacitidine; Cattle; Cell Diff

1994
The inter-relationship between polyamines and the L-arginine nitric oxide pathway in the human placenta.
    Biochemical and biophysical research communications, 1995, Jul-06, Volume: 212, Issue:1

    Topics: Amino Acid Oxidoreductases; Arginine; Cadaverine; Cell Line; Chorionic Villi; Female; Fetal Growth R

1995
Ornithine decarboxylase activity and polyamine concentrations in fetal rat brain: response to chronic hypoxic-hypoxia and/or carbon monoxide-hypoxia.
    Brain research. Developmental brain research, 1994, Nov-18, Volume: 83, Issue:1

    Topics: Animals; Animals, Newborn; Brain; Carbon Monoxide; Embryonic and Fetal Development; Female; Gestatio

1994
Influence of the polyamine, spermidine, on intestinal maturation and dietary antigen uptake in the neonatal rat.
    Journal of pediatric gastroenterology and nutrition, 1994, Volume: 19, Issue:1

    Topics: Animals; Antigens; Cortisone; Dietary Proteins; Female; Immunoglobulin G; Intestines; Ovalbumin; Pre

1994
Spermidine acetylation in N1 and N8 position in rat brain and in N-ethyl-N-nitrosourea-induced gliomas.
    Cancer letters, 1994, Jan-30, Volume: 76, Issue:2-3

    Topics: Acetylation; Acetyltransferases; Animals; Brain; Brain Neoplasms; Catalysis; Cytosol; Ethylnitrosour

1994
Postnatal changes in cochlear polyamine metabolism in the rat.
    Hearing research, 1994, Volume: 72, Issue:1-2

    Topics: Analysis of Variance; Animals; Animals, Newborn; Cochlea; Eflornithine; Female; Organ of Corti; Orni

1994
Polyamines modulate the function of transfected glutamate receptor mGluR1a.
    Neuroreport, 1993, Volume: 4, Issue:6

    Topics: Biogenic Polyamines; Cell Line; Cycloleucine; Female; Humans; Hydrolysis; Kidney; Phosphatidylinosit

1993
Ornithine decarboxylase activity and urea in liver of late-pregnant rats. Effect of streptozotocin-induced diabetes.
    Biology of the neonate, 1993, Volume: 63, Issue:1

    Topics: Animals; Blood Glucose; Blood Urea Nitrogen; Body Weight; Diabetes Mellitus, Experimental; Disease M

1993
Effects of gestational or neonatal treatment with alpha-difluoromethylornithine on ornithine decarboxylase and polyamines in developing rat brain and on adult rat neurochemistry.
    Experimental brain research, 1996, Volume: 108, Issue:3

    Topics: Animals; Animals, Newborn; Body Weight; Brain Chemistry; Cerebellum; Choline O-Acetyltransferase; Ef

1996
High levels of spermine in IVF medium as a negative predictor of subsequent success of embryo transfer.
    Journal of assisted reproduction and genetics, 1996, Volume: 13, Issue:6

    Topics: Culture Media, Conditioned; Embryo Transfer; Enzyme-Linked Immunosorbent Assay; Female; Fertilizatio

1996
Effects of spermidine treatment on neurobehavioral development in intrauterine growth retarded (IUGR) rats.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 1999, Volume: 17, Issue:7

    Topics: Animals; Female; Fetal Growth Retardation; Hand Strength; Male; Motor Activity; Posture; Pregnancy;

1999
Prolactin stimulation of iodide uptake and incorporation into protein is polyamine-dependent in mouse mammary gland explants.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 2000, Volume: 224, Issue:1

    Topics: Adenosylmethionine Decarboxylase; Animals; Eflornithine; Enzyme Inhibitors; Female; Iodides; Iodine

2000
Polyamine- and insulin-like growth factor-I-mediated proliferation of porcine uterine endometrial cells: a potential role for spermidine/spermine N(1)-acetyltransferase during peri-implantation.
    Biology of reproduction, 2001, Volume: 65, Issue:2

    Topics: Acetylation; Acetyltransferases; Animals; Blotting, Northern; Cell Division; DNA; Embryo Implantatio

2001
Putreanine in developing monkey brain: relation to polyamines.
    Journal of neurochemistry, 1979, Volume: 33, Issue:5

    Topics: Aging; Amino Acids, Diamino; Animals; Brain; Brain Chemistry; Female; Fetus; Gestational Age; Haplor

1979
Relationships between spermidine, glucocorticoid and milk proteins in different mammalian species.
    Biochemical and biophysical research communications, 1979, Oct-29, Volume: 90, Issue:4

    Topics: Animals; Caseins; Female; Hydrocortisone; Lactose Synthase; Mammary Glands, Animal; Organ Culture Te

1979
Inhibition of lymphocyte proliferation by polyamines requires ruminant-plasma polyamine oxidase.
    European journal of biochemistry, 1979, Volume: 102, Issue:1

    Topics: Animals; Blood; Cattle; Culture Media; Diamines; Female; Humans; Lymphocyte Activation; Oxidoreducta

1979
[Preliminary study of the behavior of urinary polyamines in non-pregnant conditions, in pregnant women and in abortive pathology of the 1st trimester].
    Minerva ginecologica, 1979, Volume: 31, Issue:5

    Topics: Abortion, Spontaneous; Abortion, Threatened; Adult; Age Factors; Female; Humans; Polyamines; Pregnan

1979
Isolation and characterization of a polyamine-peptide conjugate from human amniotic fluid.
    Clinica chimica acta; international journal of clinical chemistry, 1979, Aug-01, Volume: 95, Issue:3

    Topics: Amino Acids; Amniotic Fluid; Chromatography, Gel; Chromatography, High Pressure Liquid; Female; Huma

1979
Simplified micro-method for the quantitative analysis of putrescine, spermidine and spermine in urine.
    Journal of chromatography, 1978, Jan-01, Volume: 145, Issue:1

    Topics: Chromatography, Thin Layer; Dansyl Compounds; Female; Humans; Microchemistry; Pregnancy; Putrescine;

1978
Automated chromatographic analysis of human placenta polyamines..
    Biochemical medicine, 1978, Volume: 19, Issue:2

    Topics: Chromatography, Gas; Female; Gestational Age; Humans; Mass Spectrometry; Placenta; Polyamines; Pregn

1978
[Regulation of transcription in mammary gland during lactogenesis (author's transl)].
    Postepy biochemii, 1978, Volume: 24, Issue:2

    Topics: Animals; Breast; Chromatin; DNA-Directed RNA Polymerases; Female; Glucocorticoids; Humans; Insulin;

1978
Polyamines in amniotic fluid, plasma, and urine during normal pregnancy.
    American journal of obstetrics and gynecology, 1978, Nov-15, Volume: 132, Issue:6

    Topics: Amniotic Fluid; Female; Gestational Age; Humans; Polyamines; Pregnancy; Putrescine; Spermidine; Sper

1978
Role of spermidine in casein gene expression in the rabbit.
    Biochimie, 1978, Volume: 60, Issue:8

    Topics: Animals; Caseins; Female; Glucocorticoids; Hydrocortisone; Lactation; Mammary Glands, Animal; Organ

1978
Increased formation of diamines and polyamines in the pregnant rat.
    The Journal of physiology, 1978, Volume: 285

    Topics: Animals; Cadaverine; Diamines; Female; Guanidines; Histamine; Hydrolysis; Methylhistamines; Polyamin

1978
Polyamine metabolism in the brain and liver of the developing monkey.
    Journal of neurochemistry, 1975, Volume: 25, Issue:3

    Topics: Adenosylmethionine Decarboxylase; Aging; Animals; Brain; Female; Haplorhini; Liver; Macaca mulatta;

1975
The synthesis and accumulation of polyamines in reproductive organs of the rat during pregnancy.
    Biochimica et biophysica acta, 1976, Jun-23, Volume: 437, Issue:1

    Topics: Amine Oxidase (Copper-Containing); Animals; Female; Organ Specificity; Ornithine Decarboxylase; Ovar

1976
Polyamines of the human brain during normal fetal and postnatal growth and during postnatal malnutrition.
    Journal of neurochemistry, 1977, Volume: 28, Issue:6

    Topics: Aging; Brain; Brain Stem; Cerebellum; Child, Preschool; Female; Fetus; Gestational Age; Humans; Infa

1977
The effect of spermidine on the uptake of tryptophan and corticosteroids by the isolated perfused guinea-pig mammary gland.
    Biochemical Society transactions, 1976, Volume: 4, Issue:1

    Topics: Adrenal Cortex Hormones; Animals; Biological Transport; Female; Guinea Pigs; In Vitro Techniques; La

1976
Antisera to gonadotrophins and placental function in mice. I. Effect on polyamine content.
    Journal of reproduction and fertility, 1975, Volume: 43, Issue:2

    Topics: Animals; Cross Reactions; DNA; Female; Immune Sera; Luteinizing Hormone; Mice; Placenta; Polyamines;

1975
More sensitive automated detection of polyamines in physiological fluids and tissue extracts with omicron-phthalaldehyde.
    Clinical chemistry, 1975, Volume: 21, Issue:12

    Topics: Aldehydes; Amniotic Fluid; Animals; Autoanalysis; Brain Neoplasms; Evaluation Studies as Topic; Fema

1975
Mouse histidyl-tRNAs during pregnancy. Differentiation of activity profiles within and between organs.
    Differentiation; research in biological diversity, 1975, Oct-16, Volume: 4, Issue:2

    Topics: Adenosine Triphosphate; Animals; Brain; Embryo, Mammalian; Female; Histidine; Histidine-tRNA Ligase;

1975
Urinary putrescine, spermidine, and spermine in human blood and solid cancers and in an experimental gastric tumor of rats.
    Cancer research, 1976, Volume: 36, Issue:4

    Topics: Animals; Female; Humans; Leukemia; Lymphoma; Methylnitronitrosoguanidine; Neoplasms; Neoplasms, Expe

1976
Polyamine transport and metabolism in mouse mammary gland. General properties and hormonal regulation.
    The Journal of biological chemistry, 1976, May-10, Volume: 251, Issue:9

    Topics: Animals; Biological Transport, Active; Cells, Cultured; Female; Insulin; Kinetics; Mammary Glands, A

1976
[3H]MK-801 binding to the NMDA receptor complex, and its modulation in human frontal cortex during development and aging.
    Brain research, 1992, Aug-21, Volume: 588, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Child; Child, Preschool; Dizocilpine Maleate; Fem

1992
Physiological and pathological influences on sheep blood plasma amine oxidase: effect of pregnancy and experimental alloxan-induced diabetes mellitus.
    Research in veterinary science, 1991, Volume: 50, Issue:3

    Topics: Amine Oxidase (Copper-Containing); Animals; Colorimetry; Deamination; Diabetes Mellitus, Experimenta

1991
Analysis of immunosuppressive molecules associated with murine in vitro fertilized embryos.
    Fertility and sterility, 1990, Volume: 54, Issue:6

    Topics: Animals; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Culture Media; Embryo, Ma

1990
In vitro regulation of mammary glucose-6-phosphate dehydrogenase activity by palmitoyl coenzyme A, acetate, and polyamines.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1990, Volume: 193, Issue:4

    Topics: Acetates; Acyl Coenzyme A; Analysis of Variance; Animals; Biogenic Polyamines; Cattle; Culture Techn

1990
Phorbol myristate acetate stimulates RNA and casein synthesis in cultured mouse mammary gland tissues.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1986, Volume: 182, Issue:1

    Topics: Animals; Caseins; Cells, Cultured; Dose-Response Relationship, Drug; Female; Mammary Glands, Animal;

1986
Polyamine biosynthesis in the developing rabbit palate.
    Journal of craniofacial genetics and developmental biology, 1985, Volume: 5, Issue:1

    Topics: Adenosylmethionine Decarboxylase; Animals; Cell Division; DNA; Female; Gestational Age; Ornithine De

1985
Ornithine decarboxylase, transglutaminase, diamine oxidase and total diamines and polyamines in maternal liver and kidney throughout rat pregnancy.
    The Biochemical journal, 1986, Mar-01, Volume: 234, Issue:2

    Topics: Amine Oxidase (Copper-Containing); Animals; Female; Kidney; Liver; Ornithine Decarboxylase; Polyamin

1986
Effects of beta-endorphin on ornithine decarboxylase in tissues of developing rats: a potential role for this endogenous neuropeptide in the modulation of tissue growth.
    Life sciences, 1986, Jun-23, Volume: 38, Issue:25

    Topics: Animals; beta-Endorphin; Brain; Drug Interactions; Endorphins; Female; Kidney; Liver; Male; Naloxone

1986
The characterization and regulation of a polyamine-responsive, cyclic nucleotide-independent protein kinase activity in the mouse mammary gland.
    Biochimica et biophysica acta, 1985, Feb-21, Volume: 844, Issue:2

    Topics: Adenosine Triphosphate; Animals; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cyclic AMP; Cy

1985
Polyamines and nucleic acids in gestational trophoblastic tumors.
    Tumori, 1985, Feb-28, Volume: 71, Issue:1

    Topics: Adult; Choriocarcinoma; DNA, Neoplasm; Female; Humans; Hydatidiform Mole; Middle Aged; Polyamines; P

1985
Inhibition of the respiratory burst of human neutrophils by the polyamine oxidase-polyamine system.
    International journal of immunopharmacology, 1986, Volume: 8, Issue:4

    Topics: Animals; Carbon Dioxide; Catalase; Cattle; Female; Hexosephosphates; Humans; Kinetics; Male; Neutrop

1986
Polyamines and diamine oxidase activity in maternal, embryonal, and fetal tissues of rat after chronic ethanol consumption.
    Biochemical and biophysical research communications, 1987, Feb-13, Volume: 142, Issue:3

    Topics: Amine Oxidase (Copper-Containing); Animals; Brain; Cadaverine; Embryo, Mammalian; Ethanol; Female; F

1987
Purification, properties and cation activation of galactosyltransferase from lactating-rat mammary Golgi membranes.
    European journal of biochemistry, 1988, Feb-01, Volume: 171, Issue:3

    Topics: Amino Acid Sequence; Amino Acids; Animals; Clupeine; Enzyme Activation; Female; Galactosyltransferas

1988
Postpartum changes in the mechanical responses of the circular muscle of rat uterus.
    The Japanese journal of physiology, 1988, Volume: 38, Issue:3

    Topics: Animals; Calcium; Female; Indomethacin; Isotonic Solutions; Magnesium; Muscle, Smooth; Postpartum Pe

1988
[Urinary total polyamines levels in estrous cycle and during pregnancy in female rats].
    Jikken dobutsu. Experimental animals, 1988, Volume: 37, Issue:4

    Topics: Animals; Cadaverine; Embryonic and Fetal Development; Estrus; Female; Ovariectomy; Ovary; Pituitary

1988
Polyamine localization and biosynthesis in chemically fractionated rat retina.
    Journal of neurochemistry, 1986, Volume: 47, Issue:5

    Topics: Adenosylmethionine Decarboxylase; Animals; Female; Male; Ornithine Decarboxylase; Photoreceptor Cell

1986
Effects of polyamines on the mechanical and electrical activities of the isolated circular muscle of rat uterus.
    The Japanese journal of physiology, 1985, Volume: 35, Issue:6

    Topics: Animals; Cadaverine; Electric Conductivity; Electric Stimulation; Female; In Vitro Techniques; Myome

1985
Alterations of polyamines in body fluids during pregnancy in rats.
    Nihon Sanka Fujinka Gakkai zasshi, 1985, Volume: 37, Issue:2

    Topics: Animals; Body Fluids; Chromatography, High Pressure Liquid; Estradiol; Female; Polyamines; Pregnancy

1985
Pattern of human blood spermidine and spermine in prematurity.
    Clinica chimica acta; international journal of clinical chemistry, 1985, Apr-30, Volume: 147, Issue:3

    Topics: Female; Humans; Infant, Newborn; Infant, Premature; Male; Pregnancy; Spermidine; Spermine

1985
Concentrations of polyamines in umbilical blood.
    Acta medica Okayama, 1985, Volume: 39, Issue:4

    Topics: Embryonic and Fetal Development; Erythrocytes; Erythropoiesis; Female; Fetal Blood; Fetus; Gestation

1985
The side effects of antimalarial drugs indicates a polyamine involvement in both schizophrenia and depression.
    Medical hypotheses, 1985, Volume: 18, Issue:1

    Topics: Antimalarials; Depression; Female; Humans; Lupus Erythematosus, Systemic; Menstruation Disturbances;

1985
Spermidine as a possible mediator of glucocorticoid effect on milk protein synthesis in mouse mammary epithelium in vitro.
    The Journal of biological chemistry, 1974, Dec-10, Volume: 249, Issue:23

    Topics: Aldosterone; Amidines; Animals; Carboxy-Lyases; Cell Differentiation; Epithelium; Female; Glyoxal; H

1974
Polyamine biogenesis in the rat mammary gland during pregnancy and lactation.
    The Biochemical journal, 1972, Volume: 130, Issue:1

    Topics: Animals; Carbon Isotopes; Carboxy-Lyases; Epithelial Cells; Epithelium; Female; Lactation; Mammary G

1972
Polyamines in human placenta.
    Indian journal of biochemistry & biophysics, 1972, Volume: 9, Issue:3

    Topics: Female; Humans; Placenta; Polyamines; Pregnancy; Putrescine; Spermidine; Spermine

1972
Polyamine synthesis and polysome patterns in the rat uterus during the oestrous cycle.
    Endocrinology, 1973, Volume: 92, Issue:4

    Topics: Animals; Carbon Isotopes; Carboxy-Lyases; Chromatography, Thin Layer; Estrus; Female; Nucleoproteins

1973
Spermidine in hormone-dependent differentiation of mammary gland in vitro.
    Science (New York, N.Y.), 1974, Apr-05, Volume: 184, Issue:4132

    Topics: Animals; Caseins; Culture Techniques; Drug Synergism; Epithelium; Female; Hydrocortisone; Insulin; L

1974
Studies on the function of glucocorticoid in mouse mammary epithelial cell differentiation in vitro. Stimulation of glucose 6-phosphate dehydrogenase.
    The Journal of biological chemistry, 1974, Jun-10, Volume: 249, Issue:11

    Topics: Adipose Tissue; Animals; Cell Differentiation; Culture Techniques; Dose-Response Relationship, Drug;

1974
Polyamine biosynthesis in human fetal liver and brain.
    Pediatric research, 1974, Volume: 8, Issue:4

    Topics: Adult; Age Factors; Animals; Brain; Carbon Radioisotopes; Carboxy-Lyases; Female; Fetus; Humans; Liv

1974
Polyamines in human and cow's milk.
    The American journal of clinical nutrition, 1974, Volume: 27, Issue:8

    Topics: Animals; Cadaverine; Cattle; Chromatography, Thin Layer; Dansyl Compounds; Dialysis; DNA; Europe; Fe

1974
Arginase affects lactogenesis through its influence on the biosynthesis of spermidine.
    Nature, 1974, Aug-23, Volume: 250, Issue:5468

    Topics: Animals; Arginase; Culture Techniques; Female; Hydrocortisone; Insulin; Lactation; Mammary Glands, A

1974
Urinary polyamines in cancer patients.
    Cancer research, 1971, Volume: 31, Issue:11

    Topics: Brain Neoplasms; Chemistry, Clinical; Daunorubicin; Female; Hodgkin Disease; Humans; Leukemia, Lymph

1971
Polyamines in the developing rat and in supportive tissues.
    Biochimica et biophysica acta, 1972, Jan-31, Volume: 259, Issue:2

    Topics: Amniotic Fluid; Animals; Carboxy-Lyases; Embryo, Mammalian; Female; Fetus; Gestational Age; Histidin

1972