spermidine has been researched along with Pregnancy in 101 studies
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "N-ethyl-N-nitrosourea-induced rat gliomas showed a stimulation of cytosolic spermidine N-acetyltransferase activity compared with normal brain, with an increased formation of N1 and N8-acetylspermidine, suggesting the activation of two enzymes acetylating the polyamine in N1 and N8 position, respectively." | 7.69 | Spermidine acetylation in N1 and N8 position in rat brain and in N-ethyl-N-nitrosourea-induced gliomas. ( Broglia, E; Perin, A; Sessa, A; Terreni, MR, 1994) |
| "Spermidine (SPD) has shown to improve cognition, but its effect on the cognitive function of IUH offspring remains unknown." | 5.62 | Impact of intrauterine hypoxia on adolescent and adult cognitive function in rat offspring: sexual differences and the effects of spermidine intervention. ( Ai, J; Jin, Z; Li, LX; Li, TT; Mao, M; Wang, YR; Yang, L; Zhao, YJ, 2021) |
| "We aimed to evaluate the levels of Spermidine, Syndecan 1, and Glypican 3 (GPC3) in the follicle fluid of women with diminished ovarian reserve (DOR) and to examine the relationship of these markers with the number of embryos and clinical pregnancy." | 4.31 | Evaluation of Intrafollicular Syndecan 1, Glypican 3, and Spermidine Levels in Women with Diminished Ovarian Reserve. ( Cevik, O; Gokce, S; Herkiloglu, D; Turan, V, 2023) |
| "N-ethyl-N-nitrosourea-induced rat gliomas showed a stimulation of cytosolic spermidine N-acetyltransferase activity compared with normal brain, with an increased formation of N1 and N8-acetylspermidine, suggesting the activation of two enzymes acetylating the polyamine in N1 and N8 position, respectively." | 3.69 | Spermidine acetylation in N1 and N8 position in rat brain and in N-ethyl-N-nitrosourea-induced gliomas. ( Broglia, E; Perin, A; Sessa, A; Terreni, MR, 1994) |
| "Our purpose was to test the prediction that spermine levels in IVF culture supernatants measure by rapid ELISA assay correlate with subsequent success or failure to establish a pregnancy." | 3.69 | High levels of spermine in IVF medium as a negative predictor of subsequent success of embryo transfer. ( Clark, DA; Craft, I; Delcros, JG, 1996) |
| "It has been suggested that the induction of ornithine decarboxylase (ODC) activity during pregnancy might contribute to the low ureagenic flux that enables the pregnant mother to spare nitrogen and support growth." | 3.68 | Ornithine decarboxylase activity and urea in liver of late-pregnant rats. Effect of streptozotocin-induced diabetes. ( Pastor-Anglada, M; Poveda, B; Soler, C; Soley, M, 1993) |
| " The results indicate that there are 2 significant differences between the choriocarcinoma and the mole: 1) the choriocarcinoma is characterized by increased polyamine and nucleic acid levels, 2) tissues differ in their putrescine:spermidine and spermidine:spermine ratios." | 3.67 | Polyamines and nucleic acids in gestational trophoblastic tumors. ( Cecco, L; Cerra, M; Pagnano, AM; Paladini, A; Pasquinelli, R; Romano, M, 1985) |
| " At the 12th day of pregnancy, a decrease of putrescine in the liver of the mother and marked increases in putrescine, cadaverine and spermidine in embryos were observed." | 3.67 | Polyamines and diamine oxidase activity in maternal, embryonal, and fetal tissues of rat after chronic ethanol consumption. ( Desiderio, MA; Perin, A; Sessa, A, 1987) |
| "Urinary total polyamines; putrescine, spermidine and cadaverine, levels were determined in the estrous cycle and during the pregnancy in female Wistar rats." | 3.67 | [Urinary total polyamines levels in estrous cycle and during pregnancy in female rats]. ( Ohsawa, N; Torii, R, 1988) |
| " Spermidine and spermine concentrations in fetal red blood cells decreased markedly with the progress of pregnancy." | 3.67 | Concentrations of polyamines in umbilical blood. ( Eguchi, K; Hiramatsu, Y; Sekiba, K, 1985) |
| "The nature of the side effects produced by the antimalarials and a common moiety present in these drugs (spermidine) links the polyamines to both schizophrenia and depression." | 3.67 | The side effects of antimalarial drugs indicates a polyamine involvement in both schizophrenia and depression. ( Andrews, RC, 1985) |
| "The in vivo metabolism of 14C-putrescine injected to rats before, during and after pregnancy was studied." | 3.66 | Metabolism of putrescine in the pregnant rat. ( Andersson, AC; Henningsson, S, 1981) |
| "The urinary excretion of the diamines histamine, methylhistamine, putrescine and cadaverine and the polyamines spermidine and spermine was studied in rats which on the 19th day of pregnancy were subjected to various ectomizing operations." | 3.66 | On the biogenesis of diamines and polyamines in the pregnant rat. ( Andersson, AC; Henningsson, S, 1981) |
| " Spermidine and spermine continued to increase with pregnancy and retained a high level during 24-35 weeks of gestation, then decreased at term; putrescine, however, kept the low nonpregnant level during pregnancy and puerperium." | 3.66 | Alterations of red blood cells' polyamines during pregnancy and neonatal period. ( Eguchi, K; Hayase, R; Hiramatsu, Y; Sekiba, K; Yonezawa, M, 1981) |
| " Putrescine was not an inhibitor in the presence of foetal calf serum but became so in the presence of human pregnancy serum, possibly due to the action of diamine oxidase." | 3.66 | Inhibition of lymphocyte proliferation by polyamines requires ruminant-plasma polyamine oxidase. ( Allen, JC; Gaugas, JM; Hussain, JI; Smith, CJ; Thomas, JM, 1979) |
| "Spermidine concentration in rabbit mammary gland was estimated during pregnancy, lactation and after the induction of milk synthesis by prolactin and glucocorticoids in vivo and in vitro." | 3.66 | Role of spermidine in casein gene expression in the rabbit. ( Delouis, C; Devinoy, E; Houdebine, LM, 1978) |
| " The urinary excretion of histamine, methylhistamine, putrescine, cadaverine, spermidine and spermine was examined before, during and after pregnancy in rats." | 3.66 | Increased formation of diamines and polyamines in the pregnant rat. ( Andersson, AC; Henningsson, S; Rosengren, E, 1978) |
| "The pregnancy of the rat brings about profound changes of the accumulation, biosynthesis and biodegradtion of the polyamines putrescine, spermidine and spermine in the reproductive tissues." | 3.65 | The synthesis and accumulation of polyamines in reproductive organs of the rat during pregnancy. ( Guha, SK; Jänne, J, 1976) |
| " Transfer RNA of maternal mouse organs and total embryo at 13 and 17 days of pregnancy was acylated in vitro with [3H] or [14C] histidine and examined by reversed-phase plaskon chromatography." | 3.65 | Mouse histidyl-tRNAs during pregnancy. Differentiation of activity profiles within and between organs. ( de León, V; Sirlin, JL; Yang, WK, 1975) |
| "Spermidine (SPD) has shown to improve cognition, but its effect on the cognitive function of IUH offspring remains unknown." | 1.62 | Impact of intrauterine hypoxia on adolescent and adult cognitive function in rat offspring: sexual differences and the effects of spermidine intervention. ( Ai, J; Jin, Z; Li, LX; Li, TT; Mao, M; Wang, YR; Yang, L; Zhao, YJ, 2021) |
| "Putrescine was the least concentrated of these substances in both milk types." | 1.42 | Polyamine profile in ovine and caprine colostrum and milk. ( Alichanidis, E; Galitsopoulou, A; Menexes, G; Michaelidou, AM, 2015) |
| "Obesity is associated with risks for mother and infant, and the mothers' dietary habits influence breast milk composition." | 1.39 | Lower polyamine levels in breast milk of obese mothers compared to mothers with normal body weight. ( Ali, MA; Palme-Kilander, C; Strandvik, B; Yngve, A, 2013) |
| "Spermidine and histamine were competitive inhibitors of putrescine with an inhibition constant of 1." | 1.27 | Diamine oxidase activity in human decidua and endometrium. ( Gurpide, E; Holinka, CF, 1984) |
| "Only 29% of the patients with breast carcinoma had elevated levels of spermidine compared to normal female subjects." | 1.26 | Plasma spermidine concentrations in patients with tumours of the breast or prostate or testis. ( Blamey, RW; Chaisiri, P; Griffiths, K; Harper, ME; Peeling, WB, 1980) |
| "Spermine levels were not decreased and in some cases were actually increased during the course of alpha-difluoromethylornithine administration; assessment of total organ content of spermine or total polyamines per organ (putrescine + spermidine + spermine) indicated that the tissues were still actively increasing their net polyamine content despite continued inhibition of ODC." | 1.26 | Ornithine decarboxylase and polyamines in tissues of the neonatal rat: effects of alpha-difluoromethylornithine, a specific, irreversible inhibitor of ornithine decarboxylase. ( Barnes, GA; Bartolome, J; Lerea, L; Seidler, FJ; Slotkin, TA; Trepanier, PA; Weigel, SJ; Whitmore, WL, 1982) |
| "The putrescine conjugate was purified to homogeneity by column chromatography on Biogels P10 and P6 followed by ion-exchange chromatography on DEAE-Sephadex A-25." | 1.26 | Isolation and characterization of a polyamine-peptide conjugate from human amniotic fluid. ( Chan, WY; Rennert, OM; Seale, TW; Shukla, JB, 1979) |
| "Putrescine and spermine were elevated in the urine of women with normal pregnancies." | 1.26 | Polyamines in amniotic fluid, plasma, and urine during normal pregnancy. ( Campbell, JL; Christian, CD; Giles, HR; Russell, DH, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 69 (68.32) | 18.7374 |
| 1990's | 17 (16.83) | 18.2507 |
| 2000's | 6 (5.94) | 29.6817 |
| 2010's | 7 (6.93) | 24.3611 |
| 2020's | 2 (1.98) | 2.80 |
| Authors | Studies |
|---|---|
| Cai, J | 1 |
| Soloway, AH | 1 |
| Barth, RF | 1 |
| Adams, DM | 1 |
| Hariharan, JR | 1 |
| Wyzlic, IM | 1 |
| Radcliffe, K | 1 |
| Gokce, S | 1 |
| Herkiloglu, D | 1 |
| Cevik, O | 1 |
| Turan, V | 1 |
| Mao, M | 1 |
| Yang, L | 1 |
| Jin, Z | 1 |
| Li, LX | 1 |
| Wang, YR | 1 |
| Li, TT | 1 |
| Zhao, YJ | 1 |
| Ai, J | 1 |
| Ali, MA | 1 |
| Strandvik, B | 1 |
| Palme-Kilander, C | 1 |
| Yngve, A | 1 |
| Kämpfer, P | 1 |
| Glaeser, S | 1 |
| Busse, HJ | 1 |
| Eisenberg, T | 1 |
| Scholz, H | 1 |
| Wang, X | 1 |
| Ying, W | 1 |
| Dunlap, KA | 1 |
| Lin, G | 1 |
| Satterfield, MC | 1 |
| Burghardt, RC | 1 |
| Wu, G | 2 |
| Bazer, FW | 2 |
| Galitsopoulou, A | 1 |
| Michaelidou, AM | 1 |
| Menexes, G | 1 |
| Alichanidis, E | 1 |
| Basystyi, O | 1 |
| Lefèvre, PL | 1 |
| Palin, MF | 1 |
| Murphy, BD | 1 |
| Plaza-Zamora, J | 1 |
| Sabater-Molina, M | 1 |
| Rodríguez-Palmero, M | 1 |
| Rivero, M | 1 |
| Bosch, V | 1 |
| Nadal, JM | 1 |
| Zamora, S | 1 |
| Larqué, E | 1 |
| Honse, Y | 1 |
| Randall, PK | 1 |
| Leslie, SW | 1 |
| Hu, J | 1 |
| Johnson, GA | 1 |
| Spencer, TE | 1 |
| Ravikumar, N | 1 |
| Houlihan, DD | 1 |
| Morrison, JJ | 1 |
| Hyvönen, MT | 1 |
| Uimari, A | 1 |
| Keinänen, TA | 1 |
| Heikkinen, S | 1 |
| Pellinen, R | 1 |
| Wahlfors, T | 1 |
| Korhonen, A | 1 |
| Närvänen, A | 1 |
| Wahlfors, J | 1 |
| Alhonen, L | 1 |
| Jänne, J | 2 |
| Takemoto, T | 1 |
| Nagamatsu, Y | 1 |
| Oka, T | 8 |
| Chaisiri, P | 1 |
| Harper, ME | 1 |
| Blamey, RW | 1 |
| Peeling, WB | 1 |
| Griffiths, K | 1 |
| Holinka, CF | 1 |
| Gurpide, E | 1 |
| Matusik, RJ | 1 |
| Rosen, JM | 1 |
| Moore, JJ | 1 |
| Cardaman, RC | 1 |
| Lundgren, DW | 1 |
| Russell, DH | 4 |
| Slotkin, TA | 3 |
| Bartolome, J | 2 |
| Persons, D | 1 |
| Whitmore, WL | 3 |
| Tadolini, B | 1 |
| Cabrini, L | 1 |
| Sechi, AM | 1 |
| Muskiet, FA | 1 |
| van den Berg, GA | 1 |
| Kingma, AW | 1 |
| Fremouw-Ottevangers, DC | 1 |
| Halie, MR | 1 |
| Perry, JW | 4 |
| Terada, N | 1 |
| Fozard, JR | 1 |
| Prakash, NJ | 1 |
| Grove, J | 1 |
| Gahl, WA | 1 |
| Vale, AM | 1 |
| Pitot, HC | 1 |
| Seidler, FJ | 2 |
| Trepanier, PA | 1 |
| Lerea, L | 1 |
| Barnes, GA | 1 |
| Weigel, SJ | 2 |
| Andersson, AC | 3 |
| Henningsson, S | 3 |
| Rennert, OM | 2 |
| Chan, WY | 2 |
| Griesmann, G | 1 |
| Hiramatsu, Y | 2 |
| Eguchi, K | 2 |
| Yonezawa, M | 1 |
| Hayase, R | 1 |
| Sekiba, K | 2 |
| Kleczkowska, D | 1 |
| Niedbalski, W | 1 |
| Zwierzchowski, L | 1 |
| Vanella, A | 1 |
| Di Silvestro, I | 1 |
| D'Urso, G | 1 |
| Avitabile, M | 1 |
| Grasso, M | 1 |
| Rapisarda, A | 1 |
| Pinturo, R | 1 |
| Roh, SG | 1 |
| Baik, MG | 1 |
| Woo, JH | 1 |
| Choi, YJ | 1 |
| Sooranna, SR | 1 |
| Das, I | 1 |
| Packianathan, S | 1 |
| Cain, CD | 1 |
| Longo, LD | 1 |
| Capano, G | 1 |
| Bloch, KJ | 1 |
| Schiffrin, EJ | 1 |
| Dascoli, JA | 1 |
| Israel, EJ | 1 |
| Harmatz, PR | 1 |
| Sessa, A | 3 |
| Broglia, E | 1 |
| Terreni, MR | 1 |
| Perin, A | 3 |
| Brock, M | 1 |
| Henley, CM | 1 |
| Manev, RM | 1 |
| Gabellini, N | 1 |
| Manev, H | 1 |
| Poveda, B | 1 |
| Soler, C | 1 |
| Soley, M | 1 |
| Pastor-Anglada, M | 1 |
| Sparapani, M | 1 |
| Virgili, M | 1 |
| Caprini, M | 1 |
| Facchinetti, F | 1 |
| Ciani, E | 1 |
| Contestabile, A | 1 |
| Clark, DA | 2 |
| Delcros, JG | 1 |
| Craft, I | 1 |
| Uzüm, G | 1 |
| Diler, AS | 1 |
| Ziylan, Z | 1 |
| Rillema, JA | 2 |
| Collins, S | 1 |
| Williams, CH | 1 |
| Rodriguez-Sallaberry, C | 1 |
| Simmen, FA | 1 |
| Simmen, RC | 1 |
| Kremzner, LT | 1 |
| Sturman, JA | 3 |
| Bolander, FF | 1 |
| Topper, YJ | 1 |
| Allen, JC | 1 |
| Smith, CJ | 1 |
| Hussain, JI | 1 |
| Thomas, JM | 1 |
| Gaugas, JM | 1 |
| D'Anna, M | 1 |
| Seale, TW | 1 |
| Shukla, JB | 1 |
| Heby, O | 1 |
| Andersson, G | 1 |
| Porta, R | 1 |
| Servillo, L | 1 |
| Abbruzzese, A | 1 |
| Della Pietra, G | 1 |
| Chomczyński, P | 1 |
| Giles, HR | 1 |
| Christian, CD | 1 |
| Campbell, JL | 1 |
| Houdebine, LM | 1 |
| Devinoy, E | 1 |
| Delouis, C | 1 |
| Rosengren, E | 1 |
| Gaull, GE | 2 |
| Guha, SK | 1 |
| McAnulty, PA | 1 |
| Yusuf, HK | 1 |
| Dickerson, JW | 1 |
| Hey, EN | 1 |
| Waterlow, JC | 1 |
| Peters, AR | 1 |
| Mepham, TB | 1 |
| Thakur, AN | 1 |
| Sheth, AR | 2 |
| Purandare, TV | 1 |
| Munshi, SR | 1 |
| Rao, SS | 2 |
| Marton, LJ | 1 |
| Lee, PL | 1 |
| de León, V | 1 |
| Yang, WK | 1 |
| Sirlin, JL | 1 |
| Fujita, K | 1 |
| Nagatsu, T | 1 |
| Maruta, K | 3 |
| Ito, M | 1 |
| Senba, H | 1 |
| Kano, K | 1 |
| Piggott, MA | 1 |
| Perry, EK | 1 |
| Perry, RH | 1 |
| Court, JA | 1 |
| Elliott, J | 1 |
| Fowden, AL | 1 |
| Callingham, BA | 1 |
| Sharman, DF | 1 |
| Silver, M | 1 |
| Porat, O | 1 |
| Young, AJ | 1 |
| Schmotzer, WB | 1 |
| Swanson, LV | 1 |
| Waters, SB | 1 |
| Mandella, RD | 1 |
| Piacentini, M | 1 |
| Sartori, C | 1 |
| Beninati, S | 1 |
| Bargagli, AM | 1 |
| Cerù-Argento, MP | 1 |
| Bartolome, JV | 1 |
| Bartolome, MB | 1 |
| Daltner, LA | 1 |
| Evans, CJ | 1 |
| Barchas, JD | 1 |
| Kuhn, CM | 1 |
| Schanberg, SM | 1 |
| Leiderman, LJ | 1 |
| Criss, WE | 1 |
| Romano, M | 1 |
| Cecco, L | 1 |
| Cerra, M | 1 |
| Pasquinelli, R | 1 |
| Pagnano, AM | 1 |
| Paladini, A | 1 |
| Ferrante, A | 1 |
| Maxwell, GM | 1 |
| Rencis, VO | 1 |
| Allison, AC | 1 |
| Morgan, DM | 1 |
| Desiderio, MA | 1 |
| Navaratnam, N | 1 |
| Ward, S | 1 |
| Fisher, C | 1 |
| Kuhn, NJ | 1 |
| Keen, JN | 1 |
| Findlay, JB | 1 |
| Osa, T | 2 |
| Torii, R | 1 |
| Ohsawa, N | 1 |
| Ientile, R | 1 |
| Russo, P | 1 |
| Macaione, S | 1 |
| Mizoguchi, Y | 1 |
| Grillo, MA | 1 |
| Saito, H | 1 |
| Casti, A | 1 |
| Bacciottini, F | 1 |
| Orlandini, G | 1 |
| Reali, N | 1 |
| Zannino, L | 1 |
| Bernasconi, S | 1 |
| Andrews, RC | 1 |
| McVicker, TA | 2 |
| Gunaga, CK | 1 |
| Gunaga, KP | 1 |
| Purandare, MC | 1 |
| Hernandez, O | 1 |
| Ballesteros, LM | 1 |
| Mendez, D | 1 |
| Rosado, A | 1 |
| Sanguansermsri, J | 1 |
| György, P | 1 |
| Zilliken, F | 1 |
| Levy, CC | 1 |
| Schimpff, SC | 1 |
| Hawk, IA | 1 |
| Russel, DH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of an Immediate-postpartum Support by IBCLC to Women With Obesity, on Breastfeeding Performance: A Randomized Trial.[NCT02756169] | 261 participants (Actual) | Interventional | 2016-07-14 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for spermidine and Pregnancy
| Article | Year |
|---|---|
Polyamines on the reproductive landscape.
Topics: Animals; Embryo Implantation; Embryonic Development; Female; Fertilization; Gonadal Steroid Hormones | 2011 |
Clinical relevance of polyamines.
Topics: Animals; Cadaverine; Cystic Fibrosis; Diamines; Female; Growth Disorders; Humans; Kidney Failure, Ch | 1983 |
Ethanol and polyamine metabolism: physiologic and pathologic implications: a review.
Topics: Alcoholic Intoxication; Alcoholism; Animals; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Hist | 1997 |
Metabolism and function of polyamines.
Topics: Acetyltransferases; Animals; Cell Differentiation; DNA Replication; Female; Mammary Glands, Animal; | 1985 |
97 other studies available for spermidine and Pregnancy
| Article | Year |
|---|---|
Boron-containing polyamines as DNA targeting agents for neutron capture therapy of brain tumors: synthesis and biological evaluation.
Topics: Animals; Antineoplastic Agents; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; DNA | 1997 |
Evaluation of Intrafollicular Syndecan 1, Glypican 3, and Spermidine Levels in Women with Diminished Ovarian Reserve.
Topics: Adult; Embryo Transfer; Female; Fertilization in Vitro; Glypicans; Humans; Infertility, Female; Midd | 2023 |
Impact of intrauterine hypoxia on adolescent and adult cognitive function in rat offspring: sexual differences and the effects of spermidine intervention.
Topics: Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopep | 2021 |
Lower polyamine levels in breast milk of obese mothers compared to mothers with normal body weight.
Topics: Adult; Body Mass Index; Breast Feeding; Feeding Behavior; Female; Guidelines as Topic; Humans; Lacta | 2013 |
Falsochrobactrum ovis gen. nov., sp. nov., isolated from a sheep.
Topics: Animals; Bacterial Typing Techniques; Base Composition; DNA, Bacterial; Fatty Acids; Female; Genes, | 2013 |
Arginine decarboxylase and agmatinase: an alternative pathway for de novo biosynthesis of polyamines for development of mammalian conceptuses.
Topics: Agmatine; Animals; Carboxy-Lyases; Cationic Amino Acid Transporter 1; Citrulline; Embryo Implantatio | 2014 |
Polyamine profile in ovine and caprine colostrum and milk.
Topics: Animals; Biogenic Polyamines; Chromatography, High Pressure Liquid; Colostrum; Female; Goats; Milk; | 2015 |
[POLYAMINE CONCENTRATION IN ERYTHROCYTES IN THE BLOOD OF PREGNANT WOMEN WITH INTRAUTERINE GROWTH RETARDATION].
Topics: Adult; Case-Control Studies; Erythrocytes; Female; Fetal Growth Retardation; Humans; Polyamines; Pre | 2016 |
Polyamines in human breast milk for preterm and term infants.
Topics: Breast Feeding; Female; Humans; Infant, Newborn; Infant, Premature; Lactation; Milk, Human; Polyamin | 2013 |
Prenatal ethanol exposure modifies [3H]MK-801 binding to NMDA receptors: spermidine and ifenprodil.
Topics: Alternative Splicing; Animals; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Dru | 2003 |
Polyamine synthesis from proline in the developing porcine placenta.
Topics: 1-Pyrroline-5-Carboxylate Dehydrogenase; Amniotic Fluid; Animals; Arginase; Carbon Radioisotopes; Fe | 2005 |
Effects of polyamines on human umbilical artery tone in vitro.
Topics: Adult; Female; Gestational Age; Humans; In Vitro Techniques; Polyamines; Pregnancy; Spermidine; Sper | 2004 |
Polyamine-regulated unproductive splicing and translation of spermidine/spermine N1-acetyltransferase.
Topics: Acetyltransferases; Alternative Splicing; Animals; Exons; Female; Gene Expression Regulation, Enzymo | 2006 |
The study of spermidine-stimulated polypeptide synthesis in cell-free translation of mRNA from lactating mouse mammary gland.
Topics: Animals; Cell-Free System; Female; Lactation; Mammary Glands, Animal; Mice; Mice, Inbred C3H; Peptid | 1983 |
Plasma spermidine concentrations in patients with tumours of the breast or prostate or testis.
Topics: Adult; Aged; Breast Neoplasms; Female; Humans; Male; Menopause; Middle Aged; Pregnancy; Prostatic Hy | 1980 |
Diamine oxidase activity in human decidua and endometrium.
Topics: Amine Oxidase (Copper-Containing); Culture Media; Decidua; Endometrium; Estradiol; Female; Histamine | 1984 |
Prolactin regulation of casein gene expression: possible mediators.
Topics: Animals; Bucladesine; Caseins; Cyclic AMP; Cyclic GMP; Dibutyryl Cyclic GMP; Female; Kinetics; Mamma | 1980 |
Spermine-enhanced protein phosphorylation in human placenta.
Topics: Adenosine Triphosphate; Cyclic AMP; Dose-Response Relationship, Drug; Female; Humans; Molecular Weig | 1984 |
Polyamines in brain and heart of the neonatal rat: effects of inhibitors of ornithine decarboxylase and spermidine synthase.
Topics: Animals; Animals, Newborn; Brain; Cyclohexylamines; Dose-Response Relationship, Drug; Eflornithine; | 1984 |
Representative applications of heparin-sepharose in the removal of polyamines from biological materials.
Topics: Animals; Cattle; DNA; Female; Male; Membranes; Methods; Mitochondria, Heart; Polyamines; Pregnancy; | 1984 |
Total polyamines and their non-alpha-amino acid metabolites simultaneously determined in urine by capillary gas chromatography, with nitrogen-phosphorus detector; and some clinical applications.
Topics: Adolescent; Adult; Aged; Amino Acids, Diamino; Cadaverine; Child; Child, Preschool; Chromatography, | 1984 |
The regulatory function of spermidine in hormonal control of the development of mouse mammary gland in culture.
Topics: Adenosylmethionine Decarboxylase; Animals; Caseins; Cell Differentiation; Culture Techniques; Female | 1982 |
Ovarian function in the rat following irreversible inhibition of L-ornithine decarboxylase.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Eflornithine; Estrus; Female; Mitoguazone | 1980 |
Spermidine oxidase in human pregnancy serum. Probable identity with diamine oxidase.
Topics: Amine Oxidase (Copper-Containing); Female; Humans; Hydrogen-Ion Concentration; Kinetics; Oxidoreduct | 1982 |
Ornithine decarboxylase and polyamines in tissues of the neonatal rat: effects of alpha-difluoromethylornithine, a specific, irreversible inhibitor of ornithine decarboxylase.
Topics: Animals; Animals, Newborn; Brain; Carboxy-Lyases; Eflornithine; Female; Heart; Kidney; Myocardium; O | 1982 |
Metabolism of putrescine in the pregnant rat.
Topics: Animals; Carbon Dioxide; Female; Pregnancy; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Sper | 1981 |
Toxic effects of maternal methadone administration on cardiac development in the neonatal rat: potential participation of altered polyamine levels in growth impairment.
Topics: Aging; Animals; Animals, Newborn; Female; Heart; Methadone; Myocardium; Ornithine Decarboxylase; Pol | 1982 |
On the biogenesis of diamines and polyamines in the pregnant rat.
Topics: Animals; Cadaverine; Castration; Diamines; Female; Fetus; Histamine; Hysterectomy; Methylhistamines; | 1981 |
Polyamine-peptide conjugates: proposed functions.
Topics: Amino Acids; Amniotic Fluid; Female; Humans; Polyamines; Pregnancy; Proteins; Putrescine; Spermidine | 1980 |
Alterations of red blood cells' polyamines during pregnancy and neonatal period.
Topics: Cadaverine; Chromatography, High Pressure Liquid; Erythrocytes; Female; Fetal Blood; Humans; Infant, | 1981 |
Effects of spermidine and spermine on DNA synthesis in isolated nuclei and on the activity of DNA polymerases alpha and beta from the mammary gland of pregnant rabbit.
Topics: Animals; Cell Nucleus; DNA; DNA Polymerase I; DNA Polymerase II; Female; Mammary Glands, Animal; Pre | 1981 |
Polyamine levels in rat placenta during pregnancy.
Topics: Animals; Female; Placenta; Pregnancy; Pregnancy, Animal; Rats; Spermidine; Spermine; Time Factors | 1980 |
Non-hormonal factors on differentiation of bovine mammary cells.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Amino Acids; Animals; Azacitidine; Cattle; Cell Diff | 1994 |
The inter-relationship between polyamines and the L-arginine nitric oxide pathway in the human placenta.
Topics: Amino Acid Oxidoreductases; Arginine; Cadaverine; Cell Line; Chorionic Villi; Female; Fetal Growth R | 1995 |
Ornithine decarboxylase activity and polyamine concentrations in fetal rat brain: response to chronic hypoxic-hypoxia and/or carbon monoxide-hypoxia.
Topics: Animals; Animals, Newborn; Brain; Carbon Monoxide; Embryonic and Fetal Development; Female; Gestatio | 1994 |
Influence of the polyamine, spermidine, on intestinal maturation and dietary antigen uptake in the neonatal rat.
Topics: Animals; Antigens; Cortisone; Dietary Proteins; Female; Immunoglobulin G; Intestines; Ovalbumin; Pre | 1994 |
Spermidine acetylation in N1 and N8 position in rat brain and in N-ethyl-N-nitrosourea-induced gliomas.
Topics: Acetylation; Acetyltransferases; Animals; Brain; Brain Neoplasms; Catalysis; Cytosol; Ethylnitrosour | 1994 |
Postnatal changes in cochlear polyamine metabolism in the rat.
Topics: Analysis of Variance; Animals; Animals, Newborn; Cochlea; Eflornithine; Female; Organ of Corti; Orni | 1994 |
Polyamines modulate the function of transfected glutamate receptor mGluR1a.
Topics: Biogenic Polyamines; Cell Line; Cycloleucine; Female; Humans; Hydrolysis; Kidney; Phosphatidylinosit | 1993 |
Ornithine decarboxylase activity and urea in liver of late-pregnant rats. Effect of streptozotocin-induced diabetes.
Topics: Animals; Blood Glucose; Blood Urea Nitrogen; Body Weight; Diabetes Mellitus, Experimental; Disease M | 1993 |
Effects of gestational or neonatal treatment with alpha-difluoromethylornithine on ornithine decarboxylase and polyamines in developing rat brain and on adult rat neurochemistry.
Topics: Animals; Animals, Newborn; Body Weight; Brain Chemistry; Cerebellum; Choline O-Acetyltransferase; Ef | 1996 |
High levels of spermine in IVF medium as a negative predictor of subsequent success of embryo transfer.
Topics: Culture Media, Conditioned; Embryo Transfer; Enzyme-Linked Immunosorbent Assay; Female; Fertilizatio | 1996 |
Effects of spermidine treatment on neurobehavioral development in intrauterine growth retarded (IUGR) rats.
Topics: Animals; Female; Fetal Growth Retardation; Hand Strength; Male; Motor Activity; Posture; Pregnancy; | 1999 |
Prolactin stimulation of iodide uptake and incorporation into protein is polyamine-dependent in mouse mammary gland explants.
Topics: Adenosylmethionine Decarboxylase; Animals; Eflornithine; Enzyme Inhibitors; Female; Iodides; Iodine | 2000 |
Polyamine- and insulin-like growth factor-I-mediated proliferation of porcine uterine endometrial cells: a potential role for spermidine/spermine N(1)-acetyltransferase during peri-implantation.
Topics: Acetylation; Acetyltransferases; Animals; Blotting, Northern; Cell Division; DNA; Embryo Implantatio | 2001 |
Putreanine in developing monkey brain: relation to polyamines.
Topics: Aging; Amino Acids, Diamino; Animals; Brain; Brain Chemistry; Female; Fetus; Gestational Age; Haplor | 1979 |
Relationships between spermidine, glucocorticoid and milk proteins in different mammalian species.
Topics: Animals; Caseins; Female; Hydrocortisone; Lactose Synthase; Mammary Glands, Animal; Organ Culture Te | 1979 |
Inhibition of lymphocyte proliferation by polyamines requires ruminant-plasma polyamine oxidase.
Topics: Animals; Blood; Cattle; Culture Media; Diamines; Female; Humans; Lymphocyte Activation; Oxidoreducta | 1979 |
[Preliminary study of the behavior of urinary polyamines in non-pregnant conditions, in pregnant women and in abortive pathology of the 1st trimester].
Topics: Abortion, Spontaneous; Abortion, Threatened; Adult; Age Factors; Female; Humans; Polyamines; Pregnan | 1979 |
Isolation and characterization of a polyamine-peptide conjugate from human amniotic fluid.
Topics: Amino Acids; Amniotic Fluid; Chromatography, Gel; Chromatography, High Pressure Liquid; Female; Huma | 1979 |
Simplified micro-method for the quantitative analysis of putrescine, spermidine and spermine in urine.
Topics: Chromatography, Thin Layer; Dansyl Compounds; Female; Humans; Microchemistry; Pregnancy; Putrescine; | 1978 |
Automated chromatographic analysis of human placenta polyamines..
Topics: Chromatography, Gas; Female; Gestational Age; Humans; Mass Spectrometry; Placenta; Polyamines; Pregn | 1978 |
[Regulation of transcription in mammary gland during lactogenesis (author's transl)].
Topics: Animals; Breast; Chromatin; DNA-Directed RNA Polymerases; Female; Glucocorticoids; Humans; Insulin; | 1978 |
Polyamines in amniotic fluid, plasma, and urine during normal pregnancy.
Topics: Amniotic Fluid; Female; Gestational Age; Humans; Polyamines; Pregnancy; Putrescine; Spermidine; Sper | 1978 |
Role of spermidine in casein gene expression in the rabbit.
Topics: Animals; Caseins; Female; Glucocorticoids; Hydrocortisone; Lactation; Mammary Glands, Animal; Organ | 1978 |
Increased formation of diamines and polyamines in the pregnant rat.
Topics: Animals; Cadaverine; Diamines; Female; Guanidines; Histamine; Hydrolysis; Methylhistamines; Polyamin | 1978 |
Polyamine metabolism in the brain and liver of the developing monkey.
Topics: Adenosylmethionine Decarboxylase; Aging; Animals; Brain; Female; Haplorhini; Liver; Macaca mulatta; | 1975 |
The synthesis and accumulation of polyamines in reproductive organs of the rat during pregnancy.
Topics: Amine Oxidase (Copper-Containing); Animals; Female; Organ Specificity; Ornithine Decarboxylase; Ovar | 1976 |
Polyamines of the human brain during normal fetal and postnatal growth and during postnatal malnutrition.
Topics: Aging; Brain; Brain Stem; Cerebellum; Child, Preschool; Female; Fetus; Gestational Age; Humans; Infa | 1977 |
The effect of spermidine on the uptake of tryptophan and corticosteroids by the isolated perfused guinea-pig mammary gland.
Topics: Adrenal Cortex Hormones; Animals; Biological Transport; Female; Guinea Pigs; In Vitro Techniques; La | 1976 |
Antisera to gonadotrophins and placental function in mice. I. Effect on polyamine content.
Topics: Animals; Cross Reactions; DNA; Female; Immune Sera; Luteinizing Hormone; Mice; Placenta; Polyamines; | 1975 |
More sensitive automated detection of polyamines in physiological fluids and tissue extracts with omicron-phthalaldehyde.
Topics: Aldehydes; Amniotic Fluid; Animals; Autoanalysis; Brain Neoplasms; Evaluation Studies as Topic; Fema | 1975 |
Mouse histidyl-tRNAs during pregnancy. Differentiation of activity profiles within and between organs.
Topics: Adenosine Triphosphate; Animals; Brain; Embryo, Mammalian; Female; Histidine; Histidine-tRNA Ligase; | 1975 |
Urinary putrescine, spermidine, and spermine in human blood and solid cancers and in an experimental gastric tumor of rats.
Topics: Animals; Female; Humans; Leukemia; Lymphoma; Methylnitronitrosoguanidine; Neoplasms; Neoplasms, Expe | 1976 |
Polyamine transport and metabolism in mouse mammary gland. General properties and hormonal regulation.
Topics: Animals; Biological Transport, Active; Cells, Cultured; Female; Insulin; Kinetics; Mammary Glands, A | 1976 |
[3H]MK-801 binding to the NMDA receptor complex, and its modulation in human frontal cortex during development and aging.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Child; Child, Preschool; Dizocilpine Maleate; Fem | 1992 |
Physiological and pathological influences on sheep blood plasma amine oxidase: effect of pregnancy and experimental alloxan-induced diabetes mellitus.
Topics: Amine Oxidase (Copper-Containing); Animals; Colorimetry; Deamination; Diabetes Mellitus, Experimenta | 1991 |
Analysis of immunosuppressive molecules associated with murine in vitro fertilized embryos.
Topics: Animals; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Culture Media; Embryo, Ma | 1990 |
In vitro regulation of mammary glucose-6-phosphate dehydrogenase activity by palmitoyl coenzyme A, acetate, and polyamines.
Topics: Acetates; Acyl Coenzyme A; Analysis of Variance; Animals; Biogenic Polyamines; Cattle; Culture Techn | 1990 |
Phorbol myristate acetate stimulates RNA and casein synthesis in cultured mouse mammary gland tissues.
Topics: Animals; Caseins; Cells, Cultured; Dose-Response Relationship, Drug; Female; Mammary Glands, Animal; | 1986 |
Polyamine biosynthesis in the developing rabbit palate.
Topics: Adenosylmethionine Decarboxylase; Animals; Cell Division; DNA; Female; Gestational Age; Ornithine De | 1985 |
Ornithine decarboxylase, transglutaminase, diamine oxidase and total diamines and polyamines in maternal liver and kidney throughout rat pregnancy.
Topics: Amine Oxidase (Copper-Containing); Animals; Female; Kidney; Liver; Ornithine Decarboxylase; Polyamin | 1986 |
Effects of beta-endorphin on ornithine decarboxylase in tissues of developing rats: a potential role for this endogenous neuropeptide in the modulation of tissue growth.
Topics: Animals; beta-Endorphin; Brain; Drug Interactions; Endorphins; Female; Kidney; Liver; Male; Naloxone | 1986 |
The characterization and regulation of a polyamine-responsive, cyclic nucleotide-independent protein kinase activity in the mouse mammary gland.
Topics: Adenosine Triphosphate; Animals; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cyclic AMP; Cy | 1985 |
Polyamines and nucleic acids in gestational trophoblastic tumors.
Topics: Adult; Choriocarcinoma; DNA, Neoplasm; Female; Humans; Hydatidiform Mole; Middle Aged; Polyamines; P | 1985 |
Inhibition of the respiratory burst of human neutrophils by the polyamine oxidase-polyamine system.
Topics: Animals; Carbon Dioxide; Catalase; Cattle; Female; Hexosephosphates; Humans; Kinetics; Male; Neutrop | 1986 |
Polyamines and diamine oxidase activity in maternal, embryonal, and fetal tissues of rat after chronic ethanol consumption.
Topics: Amine Oxidase (Copper-Containing); Animals; Brain; Cadaverine; Embryo, Mammalian; Ethanol; Female; F | 1987 |
Purification, properties and cation activation of galactosyltransferase from lactating-rat mammary Golgi membranes.
Topics: Amino Acid Sequence; Amino Acids; Animals; Clupeine; Enzyme Activation; Female; Galactosyltransferas | 1988 |
Postpartum changes in the mechanical responses of the circular muscle of rat uterus.
Topics: Animals; Calcium; Female; Indomethacin; Isotonic Solutions; Magnesium; Muscle, Smooth; Postpartum Pe | 1988 |
[Urinary total polyamines levels in estrous cycle and during pregnancy in female rats].
Topics: Animals; Cadaverine; Embryonic and Fetal Development; Estrus; Female; Ovariectomy; Ovary; Pituitary | 1988 |
Polyamine localization and biosynthesis in chemically fractionated rat retina.
Topics: Adenosylmethionine Decarboxylase; Animals; Female; Male; Ornithine Decarboxylase; Photoreceptor Cell | 1986 |
Effects of polyamines on the mechanical and electrical activities of the isolated circular muscle of rat uterus.
Topics: Animals; Cadaverine; Electric Conductivity; Electric Stimulation; Female; In Vitro Techniques; Myome | 1985 |
Alterations of polyamines in body fluids during pregnancy in rats.
Topics: Animals; Body Fluids; Chromatography, High Pressure Liquid; Estradiol; Female; Polyamines; Pregnancy | 1985 |
Pattern of human blood spermidine and spermine in prematurity.
Topics: Female; Humans; Infant, Newborn; Infant, Premature; Male; Pregnancy; Spermidine; Spermine | 1985 |
Concentrations of polyamines in umbilical blood.
Topics: Embryonic and Fetal Development; Erythrocytes; Erythropoiesis; Female; Fetal Blood; Fetus; Gestation | 1985 |
The side effects of antimalarial drugs indicates a polyamine involvement in both schizophrenia and depression.
Topics: Antimalarials; Depression; Female; Humans; Lupus Erythematosus, Systemic; Menstruation Disturbances; | 1985 |
Spermidine as a possible mediator of glucocorticoid effect on milk protein synthesis in mouse mammary epithelium in vitro.
Topics: Aldosterone; Amidines; Animals; Carboxy-Lyases; Cell Differentiation; Epithelium; Female; Glyoxal; H | 1974 |
Polyamine biogenesis in the rat mammary gland during pregnancy and lactation.
Topics: Animals; Carbon Isotopes; Carboxy-Lyases; Epithelial Cells; Epithelium; Female; Lactation; Mammary G | 1972 |
Polyamines in human placenta.
Topics: Female; Humans; Placenta; Polyamines; Pregnancy; Putrescine; Spermidine; Spermine | 1972 |
Polyamine synthesis and polysome patterns in the rat uterus during the oestrous cycle.
Topics: Animals; Carbon Isotopes; Carboxy-Lyases; Chromatography, Thin Layer; Estrus; Female; Nucleoproteins | 1973 |
Spermidine in hormone-dependent differentiation of mammary gland in vitro.
Topics: Animals; Caseins; Culture Techniques; Drug Synergism; Epithelium; Female; Hydrocortisone; Insulin; L | 1974 |
Studies on the function of glucocorticoid in mouse mammary epithelial cell differentiation in vitro. Stimulation of glucose 6-phosphate dehydrogenase.
Topics: Adipose Tissue; Animals; Cell Differentiation; Culture Techniques; Dose-Response Relationship, Drug; | 1974 |
Polyamine biosynthesis in human fetal liver and brain.
Topics: Adult; Age Factors; Animals; Brain; Carbon Radioisotopes; Carboxy-Lyases; Female; Fetus; Humans; Liv | 1974 |
Polyamines in human and cow's milk.
Topics: Animals; Cadaverine; Cattle; Chromatography, Thin Layer; Dansyl Compounds; Dialysis; DNA; Europe; Fe | 1974 |
Arginase affects lactogenesis through its influence on the biosynthesis of spermidine.
Topics: Animals; Arginase; Culture Techniques; Female; Hydrocortisone; Insulin; Lactation; Mammary Glands, A | 1974 |
Urinary polyamines in cancer patients.
Topics: Brain Neoplasms; Chemistry, Clinical; Daunorubicin; Female; Hodgkin Disease; Humans; Leukemia, Lymph | 1971 |
Polyamines in the developing rat and in supportive tissues.
Topics: Amniotic Fluid; Animals; Carboxy-Lyases; Embryo, Mammalian; Female; Fetus; Gestational Age; Histidin | 1972 |