Page last updated: 2024-10-20

spermidine and Precancerous Conditions

spermidine has been researched along with Precancerous Conditions in 11 studies

Precancerous Conditions: Pathological conditions that tend eventually to become malignant.

Research Excerpts

ExcerptRelevanceReference
"Here we determined whether Spd treatment reduces colitis and carcinogenesis."5.72Protective Role of Spermidine in Colitis and Colon Carcinogenesis. ( Allaman, MM; Asim, M; Barry, DP; Coburn, LA; Delgado, AG; Finley, JL; Gobert, AP; Latour, YL; Luis, PB; McNamara, KM; Piazuelo, MB; Schneider, C; Sierra, JC; Singh, K; Smith, TM; Washington, MK; Wilson, KT; Zhao, S, 2022)
"Here we determined whether Spd treatment reduces colitis and carcinogenesis."1.72Protective Role of Spermidine in Colitis and Colon Carcinogenesis. ( Allaman, MM; Asim, M; Barry, DP; Coburn, LA; Delgado, AG; Finley, JL; Gobert, AP; Latour, YL; Luis, PB; McNamara, KM; Piazuelo, MB; Schneider, C; Sierra, JC; Singh, K; Smith, TM; Washington, MK; Wilson, KT; Zhao, S, 2022)
"Mean putrescine content was 1."1.28Colonic polyamine content and ornithine decarboxylase activity as markers for adenomas. ( Bartholomew, MJ; McGarrity, TJ; Pegg, AE; Peiffer, LP, 1990)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19903 (27.27)18.7374
1990's5 (45.45)18.2507
2000's2 (18.18)29.6817
2010's0 (0.00)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Gobert, AP1
Latour, YL1
Asim, M1
Barry, DP1
Allaman, MM1
Finley, JL1
Smith, TM1
McNamara, KM1
Singh, K1
Sierra, JC1
Delgado, AG1
Luis, PB1
Schneider, C1
Washington, MK1
Piazuelo, MB1
Zhao, S2
Coburn, LA1
Wilson, KT1
Tanaka, T1
Kojima, T1
Hara, A1
Sawada, H1
Mori, H1
Duranton, B3
Nsi-Emvo, E1
Schleiffer, R3
Gossé, F3
Galluser, M1
Raul, F3
Bergmann, C1
Hasselmann, M1
Perin, A2
Sessa, A2
Fan, Z1
Chen, Z1
Wang, D1
Lin, P1
Zhu, Z1
Zhang, J1
Cao, M1
McGarrity, TJ1
Peiffer, LP1
Bartholomew, MJ1
Pegg, AE1
Halline, AG1
Dudeja, PK1
Brasitus, TA1
Fan, ZF1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Immunomodulary Effects of Arginine Supplementation in Colitis and Colon Cancer[NCT01091558]204 participants (Actual)Observational2009-09-30Completed
Urinary Excretion of Acetylamantadine by Cancer Patients[NCT02277938]120 participants (Anticipated)Observational2013-08-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for spermidine and Precancerous Conditions

ArticleYear
[Spermidine radioimmunoassay in monitor of precancerous lesions of esophagus].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1988, Volume: 10, Issue:6

    Topics: Adult; Aged; China; Esophageal Neoplasms; Female; Humans; Male; Mass Screening; Middle Aged; Precanc

1988

Other Studies

10 other studies available for spermidine and Precancerous Conditions

ArticleYear
Protective Role of Spermidine in Colitis and Colon Carcinogenesis.
    Gastroenterology, 2022, Volume: 162, Issue:3

    Topics: Adenomatous Polyposis Coli Protein; alpha-Defensins; Animals; Azoxymethane; Carcinogenesis; Colitis;

2022
Chemoprevention of oral carcinogenesis by DL-alpha-difluoromethylornithine, an ornithine decarboxylase inhibitor: dose-dependent reduction in 4-nitroquinoline 1-oxide-induced tongue neoplasms in rats.
    Cancer research, 1993, Feb-15, Volume: 53, Issue:4

    Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinoma; Dose-Response Relationship, Drug; Drug Screening Assay

1993
Suppression of preneoplastic changes in the intestine of rats fed low levels of polyamines.
    Cancer research, 1997, Feb-15, Volume: 57, Issue:4

    Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Cell Movement; Colon; Colonic Neoplasms; Dimethylhydraz

1997
Nitric oxide synthase inhibition promotes carcinogen-induced preneoplastic changes in the colon of rats.
    Nitric oxide : biology and chemistry, 2000, Volume: 4, Issue:6

    Topics: Adenosylmethionine Decarboxylase; Animals; Azoxymethane; Biogenic Polyamines; Blood Pressure; Body W

2000
Blood polyamine levels after oral ornithine load, a diagnostic marker of hyperproliferative premalignant and malignant stages in a model of colon carcinogenesis.
    Cancer detection and prevention, 2000, Volume: 24, Issue:6

    Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Biomarkers, Tumor; Biotransformation; Body

2000
Changes in polyamine levels and protein synthesis rate during rat liver carcinogenesis induced by 4-dimethylaminoazobenzene.
    Cancer research, 1978, Volume: 38, Issue:1

    Topics: Animals; Carcinoma, Hepatocellular; Liver Neoplasms; Male; Neoplasm Proteins; Neoplasms, Experimenta

1978
Establishment and preliminary application of spermidine radioimmunoassay with 125I-labelled monoclonal antibody and solid phase antigen.
    Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih, 1991, Volume: 6, Issue:1

    Topics: Antibodies, Monoclonal; Biomarkers, Tumor; Drugs, Chinese Herbal; Esophageal Neoplasms; Humans; Prec

1991
Increased synthesis of N1-acetylspermidine in hepatic preneoplastic nodules and hepatomas.
    Cancer letters, 1991, Volume: 56, Issue:2

    Topics: 2-Acetylaminofluorene; Acetyltransferases; Animals; Diethylnitrosamine; Hepatectomy; Liver; Liver Ne

1991
Colonic polyamine content and ornithine decarboxylase activity as markers for adenomas.
    Cancer, 1990, Oct-01, Volume: 66, Issue:7

    Topics: Aged; Biogenic Polyamines; Biomarkers, Tumor; Colonic Polyps; Colorectal Neoplasms; Female; Humans;

1990
Premalignant alterations in rat colonic N1-acetylspermidine levels induced by 1,2-dimethylhydrazine: effects of a high corn oil dietary regimen.
    Biochimica et biophysica acta, 1989, Mar-24, Volume: 990, Issue:3

    Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Biogenic Polyamines; Colonic Neoplasms; Corn Oil; Di

1989