spermidine has been researched along with Pancreatitis in 5 studies
Pancreatitis: INFLAMMATION of the PANCREAS. Pancreatitis is classified as acute unless there are computed tomographic or endoscopic retrograde cholangiopancreatographic findings of CHRONIC PANCREATITIS (International Symposium on Acute Pancreatitis, Atlanta, 1992). The two most common forms of acute pancreatitis are ALCOHOLIC PANCREATITIS and gallstone pancreatitis.
Excerpt | Relevance | Reference |
---|---|---|
"Experimental pancreatitis is associated with activation of polyamine catabolism." | 5.37 | Association between remote organ injury and tissue polyamine homeostasis in acute experimental pancreatitis - treatment with a polyamine analogue bismethylspermine. ( Alhonen, L; Grigorenko, N; Hyvönen, MT; Jin, HT; Khomutov, AR; Lämsä, T; Nordback, I; Nordback, PH; Pörsti, I; Räty, S; Sand, J, 2011) |
" We have previously shown that pancreatic polyamine depletion in rats overexpressing the catabolic enzyme, spermidine/spermine N(1)-acetyltransferase (SSAT), results in the development of severe acute pancreatitis, and that therapeutic administration of metabolically stable alpha-methylated polyamine analogs protects the animals from pancreatitis-associated mortality." | 3.76 | Acute pancreatitis induced by activated polyamine catabolism is associated with coagulopathy: effects of alpha-methylated polyamine analogs on hemostasis. ( Alhonen, L; Fashe, T; Grigorenko, N; Hyvönen, MT; Keinänen, TA; Khomutov, AR; Sinervirta, R; Vepsäläinen, J, 2010) |
"We recently generated a transgenic rat model for acute pancreatitis, which was apparently caused by a massive depletion of pancreatic polyamines spermidine and spermine due to inducible activation of their catabolism (Alhonen, L." | 3.71 | A polyamine analogue prevents acute pancreatitis and restores early liver regeneration in transgenic rats with activated polyamine catabolism. ( Alhonen, L; Herzig, KH; Janne, J; Keinanen, T; Khomutov, AR; Rasanen, TL; Sinervirta, R; Suppola, S; Vepsalainen, J, 2002) |
"Experimental pancreatitis is associated with activation of polyamine catabolism." | 1.37 | Association between remote organ injury and tissue polyamine homeostasis in acute experimental pancreatitis - treatment with a polyamine analogue bismethylspermine. ( Alhonen, L; Grigorenko, N; Hyvönen, MT; Jin, HT; Khomutov, AR; Lämsä, T; Nordback, I; Nordback, PH; Pörsti, I; Räty, S; Sand, J, 2011) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 3 (60.00) | 29.6817 |
2010's | 2 (40.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Hyvönen, MT | 3 |
Sinervirta, R | 3 |
Keinänen, TA | 2 |
Fashe, T | 1 |
Grigorenko, N | 3 |
Khomutov, AR | 4 |
Vepsäläinen, J | 3 |
Alhonen, L | 5 |
Jin, HT | 1 |
Lämsä, T | 1 |
Nordback, PH | 1 |
Nordback, I | 1 |
Räty, S | 1 |
Pörsti, I | 1 |
Sand, J | 1 |
Rasanen, TL | 1 |
Keinanen, T | 1 |
Herzig, KH | 2 |
Suppola, S | 1 |
Janne, J | 3 |
Cerrada-Gimenez, M | 1 |
5 other studies available for spermidine and Pancreatitis
Article | Year |
---|---|
Acute pancreatitis induced by activated polyamine catabolism is associated with coagulopathy: effects of alpha-methylated polyamine analogs on hemostasis.
Topics: Acetyltransferases; Animals; Blood Coagulation; Blood Coagulation Disorders; Disease Models, Animal; | 2010 |
Association between remote organ injury and tissue polyamine homeostasis in acute experimental pancreatitis - treatment with a polyamine analogue bismethylspermine.
Topics: Acetyltransferases; Animals; Creatinine; Disease Models, Animal; Dose-Response Relationship, Drug; K | 2011 |
A polyamine analogue prevents acute pancreatitis and restores early liver regeneration in transgenic rats with activated polyamine catabolism.
Topics: alpha-Amylases; Animals; Animals, Genetically Modified; Immunohistochemistry; Liver; Mice; Pancreati | 2002 |
Acute pancreatitis induced by activation of the polyamine catabolism in gene-modified mice and rats overexpressing spermidine/spermine N1-acetyltransferase.
Topics: Acute Disease; Animals; Biomarkers; Disease Models, Animal; Mice; Mice, Transgenic; Pancreatitis; Ra | 2005 |
Role of hypusinated eukaryotic translation initiation factor 5A in polyamine depletion-induced cytostasis.
Topics: alpha-Amylases; Animals; Animals, Genetically Modified; Cell Proliferation; Eflornithine; Eukaryotic | 2007 |