Page last updated: 2024-10-20

spermidine and Ovarian Neoplasms

spermidine has been researched along with Ovarian Neoplasms in 8 studies

Ovarian Neoplasms: Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.

Research Excerpts

ExcerptRelevanceReference
"With advances in the stage of uterine cervical cancer, the frequency of abnormal levels of polyamines (concentrations greater than two standard deviations above the mean control level) became greater, and reached nearly 80% in recurrent and ovarian cancer."1.27Polyamine levels in gynecologic malignancies. ( Eguchi, K; Hayase, R; Sekiba, K, 1985)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19905 (62.50)18.7374
1990's1 (12.50)18.2507
2000's1 (12.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tummala, R1
Diegelman, P1
Hector, S1
Kramer, DL1
Clark, K1
Zagst, P1
Fetterly, G1
Porter, CW1
Pendyala, L1
Russell, DH3
Ellingson, JD1
Davis, TP1
Chanda, R1
Ganguly, AK1
Hegmans, A1
Qu, Y1
Kelland, LR1
Roberts, JD1
Farrell, N1
Szarka, G1
Pulay, T1
Csömör, S1
Schumann, B1
Hayase, R1
Eguchi, K1
Sekiba, K1
Levy, CC1
Schimpff, SC1
Hawk, IA1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
To Evaluate the Performance of a Urine Spermine Measuring Device in Predicting Prostate Biopsy Result[NCT04339920]0 participants (Actual)Observational2021-09-01Withdrawn (stopped due to No funding)
Urinary Excretion of Acetylamantadine by Cancer Patients[NCT02277938]120 participants (Anticipated)Observational2013-08-31Recruiting
To Identify Potential New Urine Marker Panel for Cancer Screening[NCT04689802]2,500 participants (Anticipated)Observational2021-01-20Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

8 other studies available for spermidine and Ovarian Neoplasms

ArticleYear
Combination effects of platinum drugs and N1, N11 diethylnorspermine on spermidine/spermine N1-acetyltransferase, polyamines and growth inhibition in A2780 human ovarian carcinoma cells and their oxaliplatin and cisplatin-resistant variants.
    Cancer chemotherapy and pharmacology, 2011, Volume: 67, Issue:2

    Topics: Acetyltransferases; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cisp

2011
Analysis of polyamines and acetyl derivatives by a single automated amino acid analyzer technique.
    Journal of chromatography, 1983, Apr-08, Volume: 273, Issue:2

    Topics: Autoanalysis; Chromatography, Ion Exchange; Female; Fluorescence; Humans; Hydrogen-Ion Concentration

1983
Diamine-oxidase activity and tissue di- and poly-amine contents of human ovarian, cervical and endometrial carcinoma.
    Cancer letters, 1995, Feb-10, Volume: 89, Issue:1

    Topics: Adult; Amine Oxidase (Copper-Containing); Biogenic Polyamines; Cadaverine; Diamines; Endometrial Neo

1995
Novel approaches to polynuclear platinum pro-drugs. Selective release of cytotoxic platinum-spermidine species through hydrolytic cleavage of carbamates.
    Inorganic chemistry, 2001, Nov-19, Volume: 40, Issue:24

    Topics: Animals; Antineoplastic Agents; Carbamates; Catalysis; Chromatography, High Pressure Liquid; Female;

2001
The importance of polyamine determination in monitoring malignant gynaecological tumours.
    Acta chirurgica Hungarica, 1988, Volume: 29, Issue:4

    Topics: Antigens, Tumor-Associated, Carbohydrate; Biomarkers, Tumor; Carcinoembryonic Antigen; Female; Human

1988
Polyamine levels in gynecologic malignancies.
    Acta medica Okayama, 1985, Volume: 39, Issue:1

    Topics: Adult; Aged; Cadaverine; Chromatography, High Pressure Liquid; Female; Genital Neoplasms, Female; Hu

1985
Urinary polyamines in cancer patients.
    Cancer research, 1971, Volume: 31, Issue:11

    Topics: Brain Neoplasms; Chemistry, Clinical; Daunorubicin; Female; Hodgkin Disease; Humans; Leukemia, Lymph

1971
Increased polyamine concentrations in the urine of human cancer patients.
    Nature: New biology, 1971, Sep-29, Volume: 233, Issue:39

    Topics: Carcinoma; Female; Hodgkin Disease; Humans; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; N

1971
Increased polyamine concentrations in the urine of human cancer patients.
    Nature: New biology, 1971, Sep-29, Volume: 233, Issue:39

    Topics: Carcinoma; Female; Hodgkin Disease; Humans; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; N

1971
Increased polyamine concentrations in the urine of human cancer patients.
    Nature: New biology, 1971, Sep-29, Volume: 233, Issue:39

    Topics: Carcinoma; Female; Hodgkin Disease; Humans; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; N

1971
Increased polyamine concentrations in the urine of human cancer patients.
    Nature: New biology, 1971, Sep-29, Volume: 233, Issue:39

    Topics: Carcinoma; Female; Hodgkin Disease; Humans; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; N

1971
Increased polyamine concentrations in the urine of human cancer patients.
    Nature: New biology, 1971, Sep-29, Volume: 233, Issue:39

    Topics: Carcinoma; Female; Hodgkin Disease; Humans; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; N

1971
Increased polyamine concentrations in the urine of human cancer patients.
    Nature: New biology, 1971, Sep-29, Volume: 233, Issue:39

    Topics: Carcinoma; Female; Hodgkin Disease; Humans; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; N

1971
Increased polyamine concentrations in the urine of human cancer patients.
    Nature: New biology, 1971, Sep-29, Volume: 233, Issue:39

    Topics: Carcinoma; Female; Hodgkin Disease; Humans; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; N

1971
Increased polyamine concentrations in the urine of human cancer patients.
    Nature: New biology, 1971, Sep-29, Volume: 233, Issue:39

    Topics: Carcinoma; Female; Hodgkin Disease; Humans; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; N

1971
Increased polyamine concentrations in the urine of human cancer patients.
    Nature: New biology, 1971, Sep-29, Volume: 233, Issue:39

    Topics: Carcinoma; Female; Hodgkin Disease; Humans; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; N

1971