spermidine has been researched along with Neurodegenerative Diseases in 6 studies
Neurodegenerative Diseases: Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Spermidine supplementation has shown beneficial effects on brain and cognitive health in animal models, and there has been preliminary evidence of memory improvement in individuals with subjective cognitive decline." | 9.51 | Effects of Spermidine Supplementation on Cognition and Biomarkers in Older Adults With Subjective Cognitive Decline: A Randomized Clinical Trial. ( Benson, GS; Eisenberg, T; Flöel, A; Grittner, U; Hofer, SJ; Horn, N; Köbe, T; Madeo, F; Magnes, C; Märschenz, S; Schilling, R; Schmitz, D; Schwarz, C; Sigrist, SJ; Stekovic, S; Wirth, M; Wurdack, K, 2022) |
| " Spermidine supplementation has shown beneficial effects on brain and cognitive health in animal models, and there has been preliminary evidence of memory improvement in individuals with subjective cognitive decline." | 5.51 | Effects of Spermidine Supplementation on Cognition and Biomarkers in Older Adults With Subjective Cognitive Decline: A Randomized Clinical Trial. ( Benson, GS; Eisenberg, T; Flöel, A; Grittner, U; Hofer, SJ; Horn, N; Köbe, T; Madeo, F; Magnes, C; Märschenz, S; Schilling, R; Schmitz, D; Schwarz, C; Sigrist, SJ; Stekovic, S; Wirth, M; Wurdack, K, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| de Medina, P | 1 |
| Paillasse, MR | 1 |
| Payré, B | 1 |
| Silvente-Poirot, S | 1 |
| Poirot, M | 1 |
| Schwarz, C | 1 |
| Benson, GS | 1 |
| Horn, N | 1 |
| Wurdack, K | 1 |
| Grittner, U | 1 |
| Schilling, R | 1 |
| Märschenz, S | 1 |
| Köbe, T | 1 |
| Hofer, SJ | 1 |
| Magnes, C | 1 |
| Stekovic, S | 1 |
| Eisenberg, T | 1 |
| Sigrist, SJ | 1 |
| Schmitz, D | 1 |
| Wirth, M | 1 |
| Madeo, F | 1 |
| Flöel, A | 1 |
| González-Polo, RA | 1 |
| Pizarro-Estrella, E | 1 |
| Yakhine-Diop, SM | 1 |
| Rodríguez-Arribas, M | 1 |
| Gómez-Sánchez, R | 1 |
| Pedro, JM | 1 |
| Fuentes, JM | 1 |
| Speldewinde, SH | 1 |
| Doronina, VA | 1 |
| Grant, CM | 1 |
| Morrison, B | 1 |
| Pringle, AK | 1 |
| McManus, T | 1 |
| Ellard, J | 1 |
| Bradley, M | 1 |
| Signorelli, F | 1 |
| Iannotti, F | 1 |
| Sundstrom, LE | 1 |
| Vivó, M | 1 |
| de Vera, N | 1 |
| Cortés, R | 1 |
| Mengod, G | 1 |
| Camón, L | 1 |
| Martínez, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Polyamine-enriched Dietary Supplementation on Cognitive Function and Biomarkers in Elderly Individuals With Subjective Cognitive Decline[NCT03094546] | Phase 2 | 100 participants (Actual) | Interventional | 2017-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for spermidine and Neurodegenerative Diseases
| Article | Year |
|---|---|
Is the Modulation of Autophagy the Future in the Treatment of Neurodegenerative Diseases?
Topics: Animals; Autophagy; Disease Models, Animal; Food; Humans; Isothiocyanates; Lithium; Neurodegenerativ | 2015 |
1 trial available for spermidine and Neurodegenerative Diseases
| Article | Year |
|---|---|
Effects of Spermidine Supplementation on Cognition and Biomarkers in Older Adults With Subjective Cognitive Decline: A Randomized Clinical Trial.
Topics: Aged; Animals; Biomarkers; Cognition; Cognitive Dysfunction; Dietary Supplements; Female; Humans; In | 2022 |
4 other studies available for spermidine and Neurodegenerative Diseases
| Article | Year |
|---|---|
Synthesis of new alkylaminooxysterols with potent cell differentiating activities: identification of leads for the treatment of cancer and neurodegenerative diseases.
Topics: Amines; Animals; Cell Differentiation; Cell Line, Tumor; Cell Survival; Cholestanols; Dendrites; Dru | 2009 |
Autophagy protects against de novo formation of the [PSI+] prion in yeast.
Topics: Autophagy; Gene Expression Regulation, Fungal; Humans; Mutation; Neurodegenerative Diseases; Oxidati | 2015 |
L-arginyl-3,4-spermidine is neuroprotective in several in vitro models of neurodegeneration and in vivo ischaemia without suppressing synaptic transmission.
Topics: Animals; Arginine; Cell Death; Cell Hypoxia; Cells, Cultured; Hippocampus; Ischemia; Neurodegenerati | 2002 |
Polyamines in the basal ganglia of human brain. Influence of aging and degenerative movement disorders.
Topics: Aged; Aged, 80 and over; Aging; Analysis of Variance; Basal Ganglia; Biogenic Polyamines; Female; Hu | 2001 |