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spermidine and Neoplasm Metastasis

spermidine has been researched along with Neoplasm Metastasis in 18 studies

Neoplasm Metastasis: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.

Research Excerpts

ExcerptRelevanceReference
"The in vitro and in vivo effects of two flavonons, naringenin (NG) and hesperitin (HP) on the proliferation rate of highly metastatic murine B16-F10 melanoma cell were investigated."7.74Enhancement of transglutaminase activity and polyamine depletion in B16-F10 melanoma cells by flavonoids naringenin and hesperitin correlate to reduction of the in vivo metastatic potential. ( Beninati, S; Forni, C; Lentini, A; Provenzano, B, 2007)
"This study was conducted to examine the polyamine transporter (PAT) recognization and antitumor effects of anthracenymethyl homospermidine (ANTMHspd) and its apoptotic mechanism in B16 melanoma cells."3.75Polyamine transporter recognization and antitumor effects of anthracenymethyl homospermidine. ( Cheng, PF; Ma, HX; Wang, CJ; Wang, JH; Xie, SQ; Zhao, J, 2009)
"The in vitro and in vivo effects of two flavonons, naringenin (NG) and hesperitin (HP) on the proliferation rate of highly metastatic murine B16-F10 melanoma cell were investigated."3.74Enhancement of transglutaminase activity and polyamine depletion in B16-F10 melanoma cells by flavonoids naringenin and hesperitin correlate to reduction of the in vivo metastatic potential. ( Beninati, S; Forni, C; Lentini, A; Provenzano, B, 2007)
"The polyamines putrescine, cadaverine, spermidine, spermine, and the amine histamine in whole blood and plasma of 42 patients with malignant melanoma were analysed after cold acid extraction and ion-exchange chromatography by fluorescence detection."3.66[Polyamine levels in blood and plasma of patients with malignant melanoma]. ( Desser, H; Gebhart, W; Kläring, WJ; Luger, T, 1982)
"DFMO did not affect pulmonary metastasis when primary tumors of control and DFMO-treated mice were matched for size."1.34Effects of polyamine depletion by alpha-difluoromethylornithine on in vitro and in vivo biological properties of 4T1 murine mammary cancer cells. ( Bruggeman, R; Demers, LM; Griffith, JW; Jun, JY; Manni, A; Verderame, MF; Washington, S, 2007)
"With the P7 sarcoma no metastases were detected following implantation; similarly, no significant changes occurred in the levels of transglutaminase activity, putrescine, spermidine or spermine during tumour growth."1.27Correlation of changes in transglutaminase activity and polyamine content of neoplastic tissue during the metastatic process. ( Elliott, BM; Griffin, M; Hand, D, 1987)
"There were 105 patients with these tumors; 319 polyamine determinations were obtained from this subset of patients."1.26Further evidence for the use of polyamines as biochemical markers for malignant tumors. ( Beal, SL; Horn, Y; Lubich, WP; Marton, LJ; Spigel, L; Walach, N, 1982)
"All 6 patients with localized malignant tumors had elevated urinary polyamine levels."1.25Urinary polyamine levels in human cancer. ( Kessler, GF; Lipton, A; Sheehan, LM, 1975)
"Patients with breast carcinoma were screened for abnormal concentrations of CEA, HCG, putrescine, spermidine, spermine, pseudouridine, N2, N2-dimethylguanosine, and 1-methylinosine."1.25Biological markers in breast carcinoma. I. Incidence of abnormalities of CEA, HCG, three polyamines, and three minor nucleosides. ( Ahmann, D; Gehrke, CW; Hansen, H; Snyder, J; Tormey, DC; Waalkes, TP; Zumwatt, RW, 1975)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199011 (61.11)18.7374
1990's2 (11.11)18.2507
2000's5 (27.78)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Xie, SQ1
Wang, JH1
Ma, HX1
Cheng, PF1
Zhao, J1
Wang, CJ1
Lentini, A2
Forni, C1
Provenzano, B2
Beninati, S3
Jun, JY1
Griffith, JW1
Bruggeman, R1
Washington, S1
Demers, LM1
Verderame, MF1
Manni, A1
Caraglia, M1
Shevchenko, A1
Abbruzzese, A2
Maldonado-Celisa, ME1
Roussia, S1
Foltzer-Jourdainne, C1
Gossé, F1
Lobstein, A1
Habold, C1
Roessner, A1
Schneider-Stock, R1
Raul, F1
Woo, KB1
Waalkes, TP3
Abeloff, MD1
Lenhard, RE1
Gehrke, CW2
Kuo, KC1
Desser, H1
Kläring, WJ1
Luger, T1
Gebhart, W1
Horn, Y1
Beal, SL1
Walach, N1
Lubich, WP1
Spigel, L1
Marton, LJ1
Cipolla, B1
Guille, F1
Moulinoux, JP1
Bansard, JY1
Roth, S1
Staerman, F1
Corbel, L1
Quemener, V1
Lobel, B1
Cardinali, M1
Lipton, A1
Sheehan, LM1
Kessler, GF1
Terabayashi, T1
Tormey, DC2
Smirnova, EV1
Khachaturian, LM1
Ahmann, D1
Zumwatt, RW1
Snyder, J1
Hansen, H1
Dunzendorfer, U1
Knöner, M1
Hand, D1
Elliott, BM1
Griffin, M1
Hibasami, H1
Tsukada, T1
Nakashima, K1

Reviews

2 reviews available for spermidine and Neoplasm Metastasis

ArticleYear
Biochemical markers in cancer of the breast.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1976, Issue:57

    Topics: Breast Neoplasms; Cadaverine; Carcinoembryonic Antigen; Chorionic Gonadotropin; Cyclophosphamide; Do

1976
[Cancer metastasis and polyamines].
    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1985, Volume: 30, Issue:5

    Topics: Adenosylmethionine Decarboxylase; Animals; Humans; Lung Neoplasms; Mammary Neoplasms, Experimental;

1985

Other Studies

16 other studies available for spermidine and Neoplasm Metastasis

ArticleYear
Polyamine transporter recognization and antitumor effects of anthracenymethyl homospermidine.
    Toxicology, 2009, Sep-19, Volume: 263, Issue:2-3

    Topics: Acetylcysteine; Animals; Anthracenes; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein;

2009
Enhancement of transglutaminase activity and polyamine depletion in B16-F10 melanoma cells by flavonoids naringenin and hesperitin correlate to reduction of the in vivo metastatic potential.
    Amino acids, 2007, Volume: 32, Issue:1

    Topics: Animals; Antineoplastic Agents; Cell Proliferation; Enzyme Activation; Estrogen Antagonists; Flavano

2007
Effects of polyamine depletion by alpha-difluoromethylornithine on in vitro and in vivo biological properties of 4T1 murine mammary cancer cells.
    Breast cancer research and treatment, 2007, Volume: 105, Issue:1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Collagen; Drug Combinations; Eflornithi

2007
Impairment of the metastatic activity of melanoma cells by transglutaminase-catalyzed incorporation of polyamines into laminin and Matrigel.
    Amino acids, 2008, Volume: 34, Issue:2

    Topics: Animals; Cell Adhesion; Cell Migration Assays; Collagen; Drug Combinations; Laminin; Matrix Metallop

2008
Modulation by polyamines of apoptotic pathways triggered by procyanidins in human metastatic SW620 cells.
    Cellular and molecular life sciences : CMLS, 2008, Volume: 65, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Colonic Neoplasms; Enzy

2008
Urinary polyamines for evaluating the course of disease for patients with small cell carcinoma of the lung.
    Cancer, 1983, Nov-01, Volume: 52, Issue:9

    Topics: Carcinoma, Small Cell; Creatinine; Humans; Lung Neoplasms; Neoplasm Metastasis; Polyamines; Putresci

1983
[Polyamine levels in blood and plasma of patients with malignant melanoma].
    Onkologie, 1982, Volume: 5, Issue:1

    Topics: Adult; Aged; Cadaverine; Clinical Laboratory Techniques; Female; Humans; Male; Melanoma; Middle Aged

1982
Further evidence for the use of polyamines as biochemical markers for malignant tumors.
    Cancer research, 1982, Volume: 42, Issue:8

    Topics: Breast Neoplasms; Clinical Laboratory Techniques; Female; Genital Neoplasms, Female; Humans; Male; N

1982
Erythrocyte polyamines and prognosis in stage D2 prostatic carcinoma patients.
    The Journal of urology, 1994, Volume: 151, Issue:3

    Topics: Aged; Aged, 80 and over; Erythrocytes; Follow-Up Studies; Humans; Male; Middle Aged; Multivariate An

1994
Differences in the post-translational modification of proteins by polyamines between weakly and highly metastatic B16 melanoma cells.
    International journal of cancer, 1993, Mar-12, Volume: 53, Issue:5

    Topics: Animals; Melanins; Melanoma, Experimental; Mice; Neoplasm Metastasis; Neoplasm Proteins; Putrescine;

1993
Urinary polyamine levels in human cancer.
    Cancer, 1975, Volume: 35, Issue:2

    Topics: Adenocarcinoma; Adenoma; Bone Neoplasms; Breast Neoplasms; Bronchial Neoplasms; Carcinoma, Squamous

1975
[Measurement of blood polyamines in patients with brain tumor--special reference to relationship between the blood levels of spermidine and spermine, and histological malignancy in patients with glioma (author's transl)].
    No to shinkei = Brain and nerve, 1977, Volume: 29, Issue:11

    Topics: Adenoma; Adolescent; Adult; Astrocytoma; Brain Neoplasms; Ependymoma; Glioma; Hemangiosarcoma; Human

1977
[Diagnostic value of determining spermidine in the urine of patients with melanoblastoma of the skin].
    Voprosy onkologii, 1976, Volume: 22, Issue:11

    Topics: Adult; Female; Humans; Lymphatic Metastasis; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Neopl

1976
Biological markers in breast carcinoma. I. Incidence of abnormalities of CEA, HCG, three polyamines, and three minor nucleosides.
    Cancer, 1975, Volume: 35, Issue:4

    Topics: Breast Neoplasms; Carcinoembryonic Antigen; Chorionic Gonadotropin; Female; Guanosine; Humans; Inosi

1975
[Therapy with inhibitors of polyamine biosynthesis in refractory prostatic carcinoma. An experimental and clinical study].
    Onkologie, 1985, Volume: 8, Issue:4

    Topics: Adenocarcinoma; Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; Carboxy-Lyases; Ca

1985
Correlation of changes in transglutaminase activity and polyamine content of neoplastic tissue during the metastatic process.
    Biochimica et biophysica acta, 1987, Oct-01, Volume: 930, Issue:3

    Topics: Animals; Cell Division; Kinetics; Neoplasm Metastasis; Putrescine; Rats; Sarcoma, Experimental; Sper

1987