spermidine has been researched along with Multiple Myeloma in 6 studies
Multiple Myeloma: A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pretreatment spermidine concentrations did not distinguish those who responded to treatment nor did they differ in patients and controls." | 1.27 | Plasma spermidine concentrations as early indication of response to therapy in human myeloma. ( Halie, MR; Houwen, B; Jurjens, H; Marrink, J; Nieweg, HO; Van Dobbenburgh, OA, 1983) |
| " Restriction enzyme analyses of genomic DNA isolated from the resistant cells indicated that the gene dosage for ornithine decarboxylase was not increased to any appreciable extent." | 1.27 | Human myeloma cells acquire resistance to difluoromethylornithine without overproducing ornithine decarboxylase. ( Alhonen-Hongisto, L; Jänne, J; Laine, R; Leinonen, P, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Van Dobbenburgh, OA | 1 |
| Houwen, B | 1 |
| Jurjens, H | 1 |
| Marrink, J | 1 |
| Halie, MR | 1 |
| Nieweg, HO | 1 |
| Russell, DH | 3 |
| Russell, SD | 1 |
| Elahi, E | 1 |
| Jones, GH | 1 |
| Fleisher, JH | 1 |
| Alhonen-Hongisto, L | 1 |
| Leinonen, P | 1 |
| Laine, R | 1 |
| Jänne, J | 1 |
| Levy, CC | 1 |
| Schimpff, SC | 1 |
| Hawk, IA | 1 |
6 other studies available for spermidine and Multiple Myeloma
| Article | Year |
|---|---|
Plasma spermidine concentrations as early indication of response to therapy in human myeloma.
Topics: Antineoplastic Agents; Humans; Multiple Myeloma; Prednisone; Prognosis; Spermidine; Time Factors; Vi | 1983 |
Relative usefulness of measuring polyamines in serum, plasma, and urine as biochemical markers of cancer.
Topics: Bleomycin; Cadaverine; Chromatography, Ion Exchange; Cytarabine; Diamines; Humans; Multiple Myeloma; | 1975 |
Effects of ribosomal wash factors and spermidine on endogenous and exogenous mRNA stimulated protein synthesis in the wheat germ cell-free system.
Topics: Animals; Kinetics; Magnesium; Multiple Myeloma; Neoplasm Proteins; Plants; Protein Biosynthesis; Rab | 1979 |
Estimation of urinary diamines and polyamines by thin-layer chromatography.
Topics: Breast Neoplasms; Cadaverine; Chromatography, Thin Layer; Dansyl Compounds; Diamines; Humans; Melano | 1975 |
Human myeloma cells acquire resistance to difluoromethylornithine without overproducing ornithine decarboxylase.
Topics: Arginase; Cell Division; Cell Line; Drug Resistance; Eflornithine; Humans; Multiple Myeloma; Ornithi | 1987 |
Urinary polyamines in cancer patients.
Topics: Brain Neoplasms; Chemistry, Clinical; Daunorubicin; Female; Hodgkin Disease; Humans; Leukemia, Lymph | 1971 |