spermidine has been researched along with Malignant Melanoma in 26 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "The in vitro and in vivo effects of two flavonons, naringenin (NG) and hesperitin (HP) on the proliferation rate of highly metastatic murine B16-F10 melanoma cell were investigated." | 7.74 | Enhancement of transglutaminase activity and polyamine depletion in B16-F10 melanoma cells by flavonoids naringenin and hesperitin correlate to reduction of the in vivo metastatic potential. ( Beninati, S; Forni, C; Lentini, A; Provenzano, B, 2007) |
| "In the course of our investigations aimed at improving the biological characteristics of iodobenzamides for melanoma therapeutic applications, four new derivatives containing a spermidine chain have been prepared and radiolabeled with (125)I." | 7.73 | Synthesis, in vitro binding and biodistribution in B16 melanoma-bearing mice of new iodine-125 spermidine benzamide derivatives. ( Bayle, M; Borel, M; Bouchon, B; Labarre, P; Madelmont, JC; Moins, N; Moreau, MF; Papon, J, 2005) |
| "Extreme inducibility of spermidine/spermine acetyltransferase (SSAT) by bis-ethyl derivatives of spermine in human large cell lung carcinoma and melanoma cells has prompted biochemical characterization of the purified enzyme." | 7.68 | Characterization of human spermidine/spermine N1-acetyltransferase purified from cultured melanoma cells. ( Bergeron, RJ; Ganis, B; Libby, PR; Porter, CW, 1991) |
| "Before, during, and after 19 courses of chemotherapy given to patients with disseminated malignant melanoma plasma spermidine levels were determined with a radioimmunoassay." | 7.67 | Spermidine level as a parameter in the treatment of patients with malignant melanoma. ( Bijzet, J; Bouman, J; Jurjens, H; Mulder, NH; Sleijfer, DT; Smit, JM; Woldring, MG, 1985) |
| "The in vitro and in vivo effects of two flavonons, naringenin (NG) and hesperitin (HP) on the proliferation rate of highly metastatic murine B16-F10 melanoma cell were investigated." | 3.74 | Enhancement of transglutaminase activity and polyamine depletion in B16-F10 melanoma cells by flavonoids naringenin and hesperitin correlate to reduction of the in vivo metastatic potential. ( Beninati, S; Forni, C; Lentini, A; Provenzano, B, 2007) |
| "In the course of our investigations aimed at improving the biological characteristics of iodobenzamides for melanoma therapeutic applications, four new derivatives containing a spermidine chain have been prepared and radiolabeled with (125)I." | 3.73 | Synthesis, in vitro binding and biodistribution in B16 melanoma-bearing mice of new iodine-125 spermidine benzamide derivatives. ( Bayle, M; Borel, M; Bouchon, B; Labarre, P; Madelmont, JC; Moins, N; Moreau, MF; Papon, J, 2005) |
| " We have found that treatment of MALME-3M human melanoma cells for 6 h with 10 micrograms/ml cycloheximide (CHX) increases ODC and SSAT mRNA 6-9-fold." | 3.69 | Differential post-transcriptional control of ornithine decarboxylase and spermidine-spermine N1-acetyltransferase by polyamines. ( Fogel-Petrovic, M; Miller, J; Porter, CW; Vujcic, S, 1996) |
| "Extreme inducibility of spermidine/spermine acetyltransferase (SSAT) by bis-ethyl derivatives of spermine in human large cell lung carcinoma and melanoma cells has prompted biochemical characterization of the purified enzyme." | 3.68 | Characterization of human spermidine/spermine N1-acetyltransferase purified from cultured melanoma cells. ( Bergeron, RJ; Ganis, B; Libby, PR; Porter, CW, 1991) |
| "Before, during, and after 19 courses of chemotherapy given to patients with disseminated malignant melanoma plasma spermidine levels were determined with a radioimmunoassay." | 3.67 | Spermidine level as a parameter in the treatment of patients with malignant melanoma. ( Bijzet, J; Bouman, J; Jurjens, H; Mulder, NH; Sleijfer, DT; Smit, JM; Woldring, MG, 1985) |
| "The polyamines putrescine, cadaverine, spermidine, spermine, and the amine histamine in whole blood and plasma of 42 patients with malignant melanoma were analysed after cold acid extraction and ion-exchange chromatography by fluorescence detection." | 3.66 | [Polyamine levels in blood and plasma of patients with malignant melanoma]. ( Desser, H; Gebhart, W; Kläring, WJ; Luger, T, 1982) |
| "The levels of polyamines (putrescine, spermidine and spermine) in erythrocytes and plasma were studied using Cloudman S-91 melanoma grown in the lungs of DBA/2 mice." | 3.66 | Raised polyamines in erythrocytes from melanoma-bearing mice and patients with solid tumours. ( Nishioka, K; Takami, H, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (57.69) | 18.7374 |
| 1990's | 8 (30.77) | 18.2507 |
| 2000's | 3 (11.54) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Moreau, MF | 1 |
| Papon, J | 1 |
| Labarre, P | 1 |
| Moins, N | 1 |
| Borel, M | 1 |
| Bayle, M | 1 |
| Bouchon, B | 1 |
| Madelmont, JC | 1 |
| Lentini, A | 1 |
| Forni, C | 1 |
| Provenzano, B | 1 |
| Beninati, S | 1 |
| Muskiet, FA | 1 |
| van den Berg, GA | 1 |
| Kingma, AW | 1 |
| Fremouw-Ottevangers, DC | 1 |
| Halie, MR | 1 |
| Seiler, N | 1 |
| Graham, A | 1 |
| Bartholeyns, J | 1 |
| Desser, H | 1 |
| Kläring, WJ | 1 |
| Luger, T | 1 |
| Gebhart, W | 1 |
| Prussak, CE | 1 |
| Russell, DH | 2 |
| Takami, H | 1 |
| Nishioka, K | 2 |
| Dewey, DL | 2 |
| Gaugas, JM | 1 |
| Kramer, D | 1 |
| Stanek, J | 1 |
| Diegelman, P | 1 |
| Regenass, U | 1 |
| Schneider, P | 1 |
| Porter, CW | 4 |
| Gutman, M | 1 |
| Beltran, PJ | 1 |
| Fan, D | 1 |
| Delworth, MG | 1 |
| Singh, RK | 1 |
| Wilson, MR | 1 |
| Fidler, IJ | 1 |
| Naredi, P | 1 |
| Hafström, L | 1 |
| Zachrisson, H | 1 |
| Rudenstam, CM | 1 |
| Lundholm, K | 1 |
| Gerner, EW | 1 |
| Kurtts, TA | 1 |
| Fuller, DJ | 1 |
| Casero, RA | 1 |
| Fujiwara, K | 1 |
| Araki, M | 1 |
| Kitagawa, T | 1 |
| Inoue, Y | 1 |
| Shappell, NW | 1 |
| Fogel-Petrovic, MF | 1 |
| Fogel-Petrovic, M | 1 |
| Vujcic, S | 1 |
| Miller, J | 1 |
| Weeks, RS | 1 |
| Vanderwerf, SM | 1 |
| Carlson, CL | 1 |
| Burns, MR | 1 |
| O'Day, CL | 1 |
| Cai, F | 1 |
| Devens, BH | 1 |
| Webb, HK | 1 |
| Abdel-Monem, MM | 1 |
| Ono, K | 1 |
| Fortuny, IE | 1 |
| Theologides, A | 1 |
| Pavel, P | 1 |
| Schwippelová, Z | 1 |
| Welch, MJ | 1 |
| Coleman, RE | 1 |
| Straatmann, MG | 1 |
| Asberry, BE | 1 |
| Primeau, JL | 1 |
| Fair, WR | 1 |
| Ter-Pogossian, MM | 1 |
| Townsend, RM | 1 |
| Banda, PW | 1 |
| Marton, LJ | 1 |
| Smirnova, EV | 1 |
| Khachaturian, LM | 1 |
| Fleisher, JH | 1 |
| Libby, PR | 1 |
| Ganis, B | 1 |
| Bergeron, RJ | 1 |
| Smit, JM | 1 |
| Jurjens, H | 1 |
| Bouman, J | 1 |
| Bijzet, J | 1 |
| Sleijfer, DT | 1 |
| Woldring, MG | 1 |
| Mulder, NH | 1 |
| Romsdahl, MM | 1 |
1 review available for spermidine and Malignant Melanoma
| Article | Year |
|---|---|
[Polyamines and malignant melanoma (author's transl)].
Topics: Animals; Humans; Mammals; Melanoma; Polyamines; Putrescine; Skin Neoplasms; Spermidine; Spermine | 1979 |
25 other studies available for spermidine and Malignant Melanoma
| Article | Year |
|---|---|
Synthesis, in vitro binding and biodistribution in B16 melanoma-bearing mice of new iodine-125 spermidine benzamide derivatives.
Topics: Animals; Benzamides; Biomarkers, Tumor; Body Burden; Cell Line, Tumor; Iodine Radioisotopes; Male; M | 2005 |
Enhancement of transglutaminase activity and polyamine depletion in B16-F10 melanoma cells by flavonoids naringenin and hesperitin correlate to reduction of the in vivo metastatic potential.
Topics: Animals; Antineoplastic Agents; Cell Proliferation; Enzyme Activation; Estrogen Antagonists; Flavano | 2007 |
Total polyamines and their non-alpha-amino acid metabolites simultaneously determined in urine by capillary gas chromatography, with nitrogen-phosphorus detector; and some clinical applications.
Topics: Adolescent; Adult; Aged; Amino Acids, Diamino; Cadaverine; Child; Child, Preschool; Chromatography, | 1984 |
Enhanced urinary excretion of N1-acetylspermidine and the presence of tumors.
Topics: Animals; Humans; Liver Neoplasms, Experimental; Mammary Neoplasms, Experimental; Melanoma; Neoplasm | 1981 |
[Polyamine levels in blood and plasma of patients with malignant melanoma].
Topics: Adult; Aged; Cadaverine; Clinical Laboratory Techniques; Female; Humans; Male; Melanoma; Middle Aged | 1982 |
Single-step high-performance liquid chromatographic method for the analysis of acetylated polyamines.
Topics: Chromatography, High Pressure Liquid; Humans; Leukemia; Male; Melanoma; Mesothelioma; Putrescine; Re | 1982 |
Raised polyamines in erythrocytes from melanoma-bearing mice and patients with solid tumours.
Topics: Animals; Erythrocytes; Female; Humans; Male; Melanoma; Mice; Mice, Inbred DBA; Middle Aged; Neoplasm | 1980 |
Inhibition of proliferation of cultured cells by polyamine and cysteine interaction.
Topics: Animals; Cell Division; Cells, Cultured; Cysteine; Drug Interactions; Melanoma; Mice; Spermidine | 1980 |
Use of 4-fluoro-L-ornithine to monitor metabolic flux through the polyamine biosynthetic pathway.
Topics: Adenosylmethionine Decarboxylase; Animals; Biogenic Polyamines; Cell Division; Cell Membrane Permeab | 1995 |
Treatment of nude mice with 4-amidinoindan -1- one2 '- amidinohydrazone, a new S-adenosylmethionine decarboxylase inhibitor, delays growth and inhibits metastasis of human melanoma cells.
Topics: Adenosylmethionine Decarboxylase; Amidines; Animals; Cell Division; Culture Media; Dose-Response Rel | 1995 |
Whole body energy expenditure protein breakdown and polyamine excretion during high dose treatment with interleukin-2 and interferon-alpha.
Topics: Aged; Carcinoma, Renal Cell; Cytokines; Energy Metabolism; Female; Humans; Interferon alpha-2; Inter | 1994 |
Stress induction of the spermidine/spermine N1-acetyltransferase by a post-transcriptional mechanism in mammalian cells.
Topics: Acetylation; Acetyltransferases; Animals; CHO Cells; Cricetinae; Ditiocarb; Eflornithine; Enzyme Ind | 1993 |
A new enzyme-linked immunosorbent assay (ELISA) for studying immunocytochemical procedures using an antiserum produced against spermidine as a model.
Topics: Enzyme-Linked Immunosorbent Assay; Humans; Immune Sera; Melanoma; Models, Biological; Neuroblastoma; | 1993 |
Regulation of spermidine/spermine N1-acetyltransferase by intracellular polyamine pools. Evidence for a functional role in polyamine homeostasis.
Topics: Acetyltransferases; Blotting, Northern; Eflornithine; Gene Expression Regulation, Enzymologic; Homeo | 1993 |
Differential post-transcriptional control of ornithine decarboxylase and spermidine-spermine N1-acetyltransferase by polyamines.
Topics: Acetyltransferases; Blotting, Northern; Cell Line; Cycloheximide; Gene Expression Regulation, Enzymo | 1996 |
Novel lysine-spermine conjugate inhibits polyamine transport and inhibits cell growth when given with DFMO.
Topics: Animals; Antineoplastic Agents; Biological Transport; Breast Neoplasms; Cell Division; Eflornithine; | 2000 |
Letter: Acetylspermidines in human urine.
Topics: Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Melanoma; Neoplasms; Skin Neoplasms; Spermidine; | 1975 |
The identification of a cell culture inhibitor in a tumour extract.
Topics: Animals; Cell Division; Cells, Cultured; Chromatography, Gel; Electrophoresis; Melanoma; Mice; Molec | 1978 |
Carbon-11-labeled methylated polyamine analogs: uptake in prostate and tumor in animal models.
Topics: Animals; Carbon Radioisotopes; Dogs; Male; Melanoma; Methylation; Mice; Neoplasm Transplantation; Ne | 1977 |
Polyamines in malignant melanoma. Urinary excretion and disease progress.
Topics: Female; Humans; Male; Melanoma; Polyamines; Putrescine; Spermidine; Spermine | 1976 |
[Diagnostic value of determining spermidine in the urine of patients with melanoblastoma of the skin].
Topics: Adult; Female; Humans; Lymphatic Metastasis; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Neopl | 1976 |
Estimation of urinary diamines and polyamines by thin-layer chromatography.
Topics: Breast Neoplasms; Cadaverine; Chromatography, Thin Layer; Dansyl Compounds; Diamines; Humans; Melano | 1975 |
Characterization of human spermidine/spermine N1-acetyltransferase purified from cultured melanoma cells.
Topics: Acetyltransferases; Coenzyme A; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Enzyme Stabil | 1991 |
Spermidine level as a parameter in the treatment of patients with malignant melanoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dacarbazine; Dactinomycin; Drug Ad | 1985 |
Elevation of putrescine and spermidine in sera of patients with solid tumors.
Topics: Autoanalysis; Breast Neoplasms; Cadaverine; Carbon Radioisotopes; Carcinoma; Chromatography, Ion Exc | 1974 |