spermidine has been researched along with Lupus Erythematosus, Systemic in 7 studies
Lupus Erythematosus, Systemic: A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The nature of the side effects produced by the antimalarials and a common moiety present in these drugs (spermidine) links the polyamines to both schizophrenia and depression." | 3.67 | The side effects of antimalarial drugs indicates a polyamine involvement in both schizophrenia and depression. ( Andrews, RC, 1985) |
| "Putrescine is a very weak SLE-causing agent, while spermine and spermidine contribute equally in triggering SLE." | 1.32 | Calculating the etiology of systemic lupus erythematosus. ( Adhami, E, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, X | 1 |
| Stearns, NA | 1 |
| Li, X | 1 |
| Pisetsky, DS | 1 |
| Adhami, E | 1 |
| Thomas, TJ | 4 |
| Thomas, T | 3 |
| Gunnia, UB | 2 |
| Seibold, JR | 1 |
| Meryhew, NL | 1 |
| Messner, RP | 1 |
| Andrews, RC | 1 |
7 other studies available for spermidine and Lupus Erythematosus, Systemic
| Article | Year |
|---|---|
The effect of polyamines on the binding of anti-DNA antibodies from patients with SLE and normal human subjects.
Topics: Antibodies, Antinuclear; Antibody Specificity; Antigen-Antibody Complex; Case-Control Studies; DNA; | 2014 |
Calculating the etiology of systemic lupus erythematosus.
Topics: Animals; Autoimmunity; Humans; Lupus Erythematosus, Systemic; Models, Immunological; Polyamines; Put | 2004 |
Polyamine-induced Z-DNA conformation in plasmids containing (dA-dC)n.(dG-dT)n inserts and increased binding of lupus autoantibodies to the Z-DNA form of plasmids.
Topics: Animals; Antibodies, Antinuclear; Binding Sites, Antibody; Biogenic Polyamines; Cattle; DNA; Humans; | 1994 |
Reversal of the abnormal development of T cell subpopulations in the thymus of autoimmune MRL-lpr/lpr mice by a polyamine biosynthesis inhibitor.
Topics: Animals; Autoimmunity; CD4-CD8 Ratio; Disease Models, Animal; Eflornithine; Lupus Erythematosus, Sys | 1992 |
Restoration of the DNA binding activity of estrogen receptor in MRL-lpr/lpr mice by a polyamine biosynthesis inhibitor.
Topics: Animals; DNA; Down-Regulation; Eflornithine; Female; Lupus Erythematosus, Systemic; Mice; Mice, Inbr | 1991 |
Enhanced binding of lupus sera to the polyamine-induced left-handed Z-DNA form of polynucleotides.
Topics: Autoantibodies; DNA; Enzyme-Linked Immunosorbent Assay; Humans; Immunoglobulin G; Lupus Erythematosu | 1990 |
The side effects of antimalarial drugs indicates a polyamine involvement in both schizophrenia and depression.
Topics: Antimalarials; Depression; Female; Humans; Lupus Erythematosus, Systemic; Menstruation Disturbances; | 1985 |