spermidine has been researched along with Liver Cirrhosis in 4 studies
Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Spermidine supplementation is a potentially clinically meaningful approach to treating and curing liver fibrosis, preventing cirrhosis and HCC in patients." | 8.31 | Spermidine suppresses the activation of hepatic stellate cells to cure liver fibrosis through autophagy activator MAP1S. ( Ao, J; Jiang, X; Liang, M; Liang, X; Liu, L; Liu, Z; Shi, B; Wang, W; Xu, F; Xu, G; Ye, M; Yu, Z; Zhang, Y; Zhou, X, 2023) |
| "Liver fibrosis and hepatocellular carcinoma (HCC) have worldwide impact but continue to lack safe, low cost, and effective treatments." | 5.46 | Spermidine Prolongs Lifespan and Prevents Liver Fibrosis and Hepatocellular Carcinoma by Activating MAP1S-Mediated Autophagy. ( Huang, H; Jiang, X; Li, W; Liu, L; Xu, G; Yue, F; Zou, J, 2017) |
| "Spermidine supplementation is a potentially clinically meaningful approach to treating and curing liver fibrosis, preventing cirrhosis and HCC in patients." | 4.31 | Spermidine suppresses the activation of hepatic stellate cells to cure liver fibrosis through autophagy activator MAP1S. ( Ao, J; Jiang, X; Liang, M; Liang, X; Liu, L; Liu, Z; Shi, B; Wang, W; Xu, F; Xu, G; Ye, M; Yu, Z; Zhang, Y; Zhou, X, 2023) |
| "Liver fibrosis and hepatocellular carcinoma (HCC) have worldwide impact but continue to lack safe, low cost, and effective treatments." | 1.46 | Spermidine Prolongs Lifespan and Prevents Liver Fibrosis and Hepatocellular Carcinoma by Activating MAP1S-Mediated Autophagy. ( Huang, H; Jiang, X; Li, W; Liu, L; Xu, G; Yue, F; Zou, J, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shi, B | 2 |
| Wang, W | 1 |
| Ye, M | 1 |
| Liang, M | 1 |
| Yu, Z | 1 |
| Zhang, Y | 1 |
| Liu, Z | 1 |
| Liang, X | 1 |
| Ao, J | 1 |
| Xu, F | 1 |
| Xu, G | 2 |
| Jiang, X | 2 |
| Zhou, X | 1 |
| Liu, L | 3 |
| Yue, F | 2 |
| Li, W | 1 |
| Zou, J | 1 |
| Huang, H | 1 |
| Liu, P | 1 |
| de la Vega, MR | 1 |
| Dodson, M | 1 |
| Fang, D | 1 |
| Chapman, E | 1 |
| Zhang, DD | 1 |
| Sugimoto, H | 1 |
| Sakurai, S | 1 |
| Abe, T | 1 |
| Takagi, H | 1 |
| Takahashi, H | 1 |
| Takezawa, J | 1 |
| Nagamine, T | 1 |
| Matsuzaki, S | 1 |
4 other studies available for spermidine and Liver Cirrhosis
| Article | Year |
|---|---|
Spermidine suppresses the activation of hepatic stellate cells to cure liver fibrosis through autophagy activator MAP1S.
Topics: Animals; Autophagy; Carcinoma, Hepatocellular; Fatty Liver; Fibrosis; Hepatic Stellate Cells; Humans | 2023 |
Spermidine Prolongs Lifespan and Prevents Liver Fibrosis and Hepatocellular Carcinoma by Activating MAP1S-Mediated Autophagy.
Topics: Animals; Autophagy; Carcinoma, Hepatocellular; Humans; Liver Cirrhosis; Liver Neoplasms; Mice; Mice, | 2017 |
Spermidine Confers Liver Protection by Enhancing NRF2 Signaling Through a MAP1S-Mediated Noncanonical Mechanism.
Topics: Animals; Autophagy; Drug Evaluation, Preclinical; HEK293 Cells; Hepatic Stellate Cells; Humans; Kelc | 2019 |
Elevation of N1-acetylspermidine and putrescine in hepatic tissues of patients with fulminant hepatitis and liver cirrhosis.
Topics: Acetyltransferases; Adult; Aged; Female; Hepatic Encephalopathy; Hepatitis; Humans; Liver; Liver Cir | 1994 |