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spermidine and Leukemia L 1210

spermidine has been researched along with Leukemia L 1210 in 65 studies

Research Excerpts

ExcerptRelevanceReference
"Spermidine was depleted in treated L1210 cells but was only partly reduced in treated R20 cells."1.29Effects of chronic 5'-([(Z)-4-amino-2-butenyl]methylamino)-5'-deoxy- adenosine (AbeAdo) treatment on polyamine and eIF-5A metabolism in AbeAdo-sensitive and -resistant L1210 murine leukaemia cells. ( Byers, TL; Pegg, AE; Wechter, RS; Wiest, L, 1993)
"Putrescine was similarly ineffective, supporting growth at 13% of control and viability at 7%."1.28Cellular characterization of a new irreversible inhibitor of S-adenosylmethionine decarboxylase and its use in determining the relative abilities of individual polyamines to sustain growth and viability of L1210 cells. ( Bukin, YV; Khomutov, AR; Khomutov, RM; Kramer, DL; Porter, CW, 1989)

Research

Studies (65)

TimeframeStudies, this research(%)All Research%
pre-199032 (49.23)18.7374
1990's30 (46.15)18.2507
2000's2 (3.08)29.6817
2010's1 (1.54)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lakanen, JR3
Coward, JK3
Pegg, AE7
Bergeron, RJ15
Feng, Y2
Weimar, WR3
McManis, JS2
Dimova, H1
Porter, C1
Raisler, B1
Phanstiel, O2
Tsen, C1
Iltis, M1
Kaur, N1
Bayer, C1
Delcros, JG3
von Kalm, L1
Tomasi, S1
Renault, J2
Martin, B1
Duhieu, S1
Cerec, V1
Le Roch, M1
Uriac, P1
Seppänen, P1
Ruohola, H1
Jänne, J3
Cavanaugh, PF4
Kline, SJ1
Hughes, RG1
Elliott, GT1
Porter, CW19
Pavelic, ZP2
Alhonen-Hongisto, L1
Fagerström, R1
Laine, R1
Elo, H1
Casero, RA2
Blair, DG1
Byczkowski, JZ1
Miller, J1
Stolowich, NJ1
Wang, Z2
Fries, D2
Blankenship, J2
Poulin, R3
Pelletier, G1
Kramer, D2
Stanek, J3
Diegelman, P1
Regenass, U2
Schneider, P2
Cullis, PM1
Green, RE1
Malone, ME1
Merson-Davies, L1
Weaver, R1
Grillo, MA2
Colombatto, S2
Liu, CZ1
Luchetta, GR1
Wu, Q1
Ortiz-Ocasio, J1
Vinson, JR1
Byers, TL2
Fontana, L1
Yuan, ZM1
Egorin, MJ2
Rosen, DM2
Simon, MA1
Callery, PS2
Stjernborg, L1
Heby, O8
Mamont, P1
Persson, L5
Wiest, L1
Wechter, RS1
Ask, A2
Seiler, N4
Khomutov, AR2
Shvetsov, AS1
Vepsalainen, J1
Dramer, DL1
Hyvonen, T1
Keinanen, T1
Eloranta, TO1
Khomutov, RM2
Li, Y1
MacKerell, AD1
Ballesteros, MF1
Wu, YY1
Blamble, DA1
Vaultier, M2
Le Roch, N2
Havouis, R2
Moulinoux, JP3
Dorhout, B1
Odink, MF1
de Hoog, E1
Kingma, AW1
van der Veer, E1
Muskiet, FA1
Felschow, DM1
Mi, Z1
Frei, J1
Douaud, F1
Müller, R1
Zimmerman, CO1
McCosar, BH1
Yao, H1
Smith, RE1
Hegmans, A1
Qu, Y1
Kelland, LR1
Roberts, JD1
Farrell, N1
Foa, P1
Paile, W1
Yuen, TL1
Jones, WA1
Rytömaa, T1
Newton, NE2
Abdel-Monem, MM2
Ohno, K1
Canellakis, ES1
Bellantone, RA1
Caravatti, G1
Mett, H1
Müller, M1
Matter, A1
Vertino, P1
Khan, NA1
Quemener, V1
Vertino, PM1
Beerman, TA1
Kelly, EJ1
Autelli, R1
Holm, I2
Wotring, LL1
Townsend, LB1
Jones, LM1
Borysko, KZ1
Gildersleeve, DL1
Parker, WB1
Kramer, DL2
Bukin, YV1
Pommier, Y1
Kerrigan, D1
Kohn, K1
Libby, PR1
Henderson, M1
Ganis, B2
Vinson, T1
Marton, LJ1
Madhubala, R1
Secrist, JA1
Sunkara, PS1
Zwolshen, JH1
Prakash, NJ1
Bowlin, TL1
McManis, J1
Umeda, Y2
Moriguchi, M2
Kuroda, H2
Nakamura, T2
Fujii, A1
Iinuma, H2
Takeuchi, T2
Umezawa, H2
Stolowich, N1
Kelly, E1
Tukalo, D1
Frankfurt, OS1
Russell, DH4
Hacker, B1
McDermott, BJ1
Sauter, S1

Reviews

1 review available for spermidine and Leukemia L 1210

ArticleYear
Polyamine transport in cells.
    Biochemical Society transactions, 1994, Volume: 22, Issue:4

    Topics: Animals; Biological Transport; Cells, Cultured; Escherichia coli; Humans; Kinetics; Leukemia L1210;

1994

Other Studies

64 other studies available for spermidine and Leukemia L 1210

ArticleYear
alpha-Methyl polyamines: metabolically stable spermidine and spermine mimics capable of supporting growth in cells depleted of polyamines.
    Journal of medicinal chemistry, 1992, Feb-21, Volume: 35, Issue:4

    Topics: Animals; Cell Division; Cell Line, Transformed; Colonic Neoplasms; Eflornithine; Humans; Leukemia L1

1992
A comparison of structure-activity relationships between spermidine and spermine analogue antineoplastics.
    Journal of medicinal chemistry, 1997, May-09, Volume: 40, Issue:10

    Topics: Acetyltransferases; Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; Cell Division;

1997
A Drosophila model to identify polyamine-drug conjugates that target the polyamine transporter in an intact epithelium.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Animals; Anthracenes; Biological Transport; Carrier Proteins; Cell Line, Tumor; CHO Cells; Cricetina

2008
Targeting the polyamine transport system with benzazepine- and azepine-polyamine conjugates.
    Journal of medicinal chemistry, 2010, Nov-11, Volume: 53, Issue:21

    Topics: Animals; Antineoplastic Agents; Azepines; Benzazepines; Biological Transport; Cell Proliferation; CH

2010
Ethylglyoxal bis(guanylhydrazone) as an inhibitor of polyamine biosynthesis in L1210 leukemia cells.
    Biochimica et biophysica acta, 1984, Apr-16, Volume: 803, Issue:4

    Topics: Adenosylmethionine Decarboxylase; Animals; Cell Division; Guanidines; Leukemia L1210; Microscopy, El

1984
Antineoplastic and antiherpetic activity of spermidine catecholamide iron chelators.
    Biochemical and biophysical research communications, 1984, Jun-29, Volume: 121, Issue:3

    Topics: Animals; Antineoplastic Agents; Antiviral Agents; Iron Chelating Agents; Leukemia L1210; Mice; Sider

1984
Enhancement of 1,3-bis(2-chloroethyl)-1-nitrosourea-induced cytotoxicity and DNA damage by alpha-difluoromethylornithine in L1210 leukemia cells.
    Cancer research, 1984, Volume: 44, Issue:9

    Topics: Animals; Carmustine; Cell Survival; DNA, Neoplasm; Drug Synergism; Eflornithine; Kinetics; Leukemia

1984
Different efflux rates may determine the cellular accumulation of various bis(guanylhydrazones).
    The Biochemical journal, 1984, Jul-01, Volume: 221, Issue:1

    Topics: Animals; Cells, Cultured; Eflornithine; Guanidines; Leukemia L1210; Mice; Mitoguazone; Ornithine; Sp

1984
Treatment with alpha-difluoromethylornithine plus a spermidine analog leads to spermine depletion and growth inhibition in cultured L1210 leukemia cells.
    Journal of cellular physiology, 1984, Volume: 121, Issue:3

    Topics: Animals; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Eflornithine; Leukemia L1

1984
Stimulation of RNA polymerases I and II from mouse L1210 leukemia and Ehrlich ascites carcinoma cells by spermine and spermidine and its modification by ammonium sulfate.
    The International journal of biochemistry, 1984, Volume: 16, Issue:12

    Topics: Ammonium Sulfate; Animals; Carcinoma, Ehrlich Tumor; Cell Nucleus; Drug Interactions; Kinetics; Leuk

1984
Interactions between bis(guanylhydrazones) and polyamines in isolated mitochondria.
    General pharmacology, 1983, Volume: 14, Issue:6

    Topics: Animals; Antineoplastic Agents; Carbanilides; Dinitrophenols; Drug Interactions; Guanidines; In Vitr

1983
Aliphatic chain length specificity of the polyamine transport system in ascites L1210 leukemia cells.
    Cancer research, 1984, Volume: 44, Issue:1

    Topics: Animals; Biological Transport; Kinetics; Leukemia L1210; Mice; Polyamines; Spermidine; Structure-Act

1984
Spermidine requirement for cell proliferation in eukaryotic cells: structural specificity and quantitation.
    Science (New York, N.Y.), 1983, Mar-04, Volume: 219, Issue:4588

    Topics: Animals; Cell Division; Cell Physiological Phenomena; Eukaryotic Cells; Leukemia L1210; Mice; Ornith

1983
Biological properties of N4-spermidine derivatives and their potential in anticancer chemotherapy.
    Cancer research, 1982, Volume: 42, Issue:10

    Topics: Animals; Antineoplastic Agents; Drug Evaluation, Preclinical; Glycolysis; Leukemia L1210; Mice; Oxyg

1982
Similarity of effects of N8-acetylspermidine and its deacetylase inhibitor on stimulating the growth of L1210 cells.
    Proceedings of the Western Pharmacology Society, 1995, Volume: 38

    Topics: Amidohydrolases; Animals; Biogenic Polyamines; Cell Division; Diamines; Leukemia L1210; Mice; Spermi

1995
Induction of apoptosis by excessive polyamine accumulation in ornithine decarboxylase-overproducing L1210 cells.
    The Biochemical journal, 1995, Nov-01, Volume: 311 ( Pt 3)

    Topics: Animals; Apoptosis; Biogenic Polyamines; DNA, Neoplasm; Hydrogen Peroxide; Leukemia L1210; Mice; Orn

1995
Use of 4-fluoro-L-ornithine to monitor metabolic flux through the polyamine biosynthetic pathway.
    Biochemical pharmacology, 1995, Oct-26, Volume: 50, Issue:9

    Topics: Adenosylmethionine Decarboxylase; Animals; Biogenic Polyamines; Cell Division; Cell Membrane Permeab

1995
Targeting of tumour cells with polyamine-drug conjugates.
    Biochemical Society transactions, 1994, Volume: 22, Issue:4

    Topics: Animals; Biological Transport; Cell Line; Cell Survival; Chlorambucil; Cross-Linking Reagents; Leuke

1994
Antiproliferative properties of polyamine analogues: a structure-activity study.
    Journal of medicinal chemistry, 1994, Oct-14, Volume: 37, Issue:21

    Topics: Acetyltransferases; Adenosylmethionine Decarboxylase; Animals; Binding, Competitive; Cell Division;

1994
The role of hypusine depletion in cytostasis induced by S-adenosyl-L-methionine decarboxylase inhibition: new evidence provided by 1-methylspermidine and 1,12-dimethylspermine.
    The Biochemical journal, 1994, Oct-15, Volume: 303 ( Pt 2)

    Topics: Adenosylmethionine Decarboxylase; Animals; Cell Division; CHO Cells; Chromatography, High Pressure L

1994
Regulation of spermidine transport in L1210 cells.
    The International journal of biochemistry, 1993, Volume: 25, Issue:10

    Topics: Animals; Biological Transport; Leukemia L1210; Mice; Spermidine

1993
Cellular pharmacology of N1- and N8-aziridinyl analogues of spermidine.
    Cancer research, 1994, Feb-01, Volume: 54, Issue:3

    Topics: Alkylating Agents; Animals; Aziridines; Eflornithine; Leukemia L1210; Mice; Polyamines; Spermidine;

1994
Polyamine-mediated regulation of S-adenosylmethionine decarboxylase expression in mammalian cells. Studies using 5'-([(Z)-4-amino-2-butenyl]methylamino)-5'-deoxyadenosine, a suicide inhibitor of the enzyme.
    European journal of biochemistry, 1993, Jun-15, Volume: 214, Issue:3

    Topics: Adenosylmethionine Decarboxylase; Animals; Deoxyadenosines; Enzyme Precursors; Gene Expression Regul

1993
Effects of chronic 5'-([(Z)-4-amino-2-butenyl]methylamino)-5'-deoxy- adenosine (AbeAdo) treatment on polyamine and eIF-5A metabolism in AbeAdo-sensitive and -resistant L1210 murine leukaemia cells.
    The Biochemical journal, 1993, Feb-15, Volume: 290 ( Pt 1)

    Topics: Adenosylmethionine Decarboxylase; Animals; Cell Division; Deoxyadenosines; Drug Resistance; Eukaryot

1993
Enhancement of the spermidine uptake system and lethal effects of spermidine overaccumulation in ornithine decarboxylase-overproducing L1210 cells under hyposmotic stress.
    The Journal of biological chemistry, 1993, Mar-05, Volume: 268, Issue:7

    Topics: Animals; Biological Transport; Cell Division; Cell Survival; Leukemia L1210; Mice; Ornithine Decarbo

1993
Antileukemic effects of non-metabolizable derivatives of spermidine and spermine.
    Cancer letters, 1993, Apr-15, Volume: 69, Issue:1

    Topics: Adenosylmethionine Decarboxylase; Animals; Drug Synergism; Eflornithine; Female; Leukemia L1210; Mic

1993
Stable intracellular acidification upon polyamine depletion induced by alpha-difluoromethylornithine or N1,N12-bis(ethyl)spermine in L1210 leukaemia cells.
    The Biochemical journal, 1995, Dec-15, Volume: 312 ( Pt 3)

    Topics: Animals; Antineoplastic Agents; Bicarbonates; Eflornithine; Hydrogen-Ion Concentration; Leukemia L12

1995
[New aminooxy analogs of biogenic polyamines].
    Bioorganicheskaia khimiia, 1996, Volume: 22, Issue:7

    Topics: Animals; Cell Division; Cell Line; Cricetinae; Leukemia L1210; Putrescine; Spermidine; Spermine; Tum

1996
Comparative molecular field analysis-based predictive model of structure-function relationships of polyamine transport inhibitors in L1210 cells.
    Cancer research, 1997, Jan-15, Volume: 57, Issue:2

    Topics: Animals; Leukemia L1210; Mice; Models, Chemical; Polyamines; Spermidine; Structure-Activity Relation

1997
Bis(7-amino-4-azaheptyl)dimethylsilane: a new tetramine with polyamine-like features. Effects on cell growth.
    Anti-cancer drug design, 1997, Volume: 12, Issue:1

    Topics: Animals; Antineoplastic Agents; Cell Division; Drug Screening Assays, Antitumor; Leukemia L1210; Neo

1997
4-Amidinoindan-1-one 2'-amidinohydrazone (CGP 48664A) exerts in vitro growth inhibitory effects that are not only related to S-adenosylmethionine decarboxylase (SAMdc) inhibition.
    Biochimica et biophysica acta, 1997, Apr-17, Volume: 1335, Issue:1-2

    Topics: Adenosylmethionine Decarboxylase; Amidines; Animals; Antineoplastic Agents; Cell Division; Deoxyaden

1997
Selective labelling of cell-surface polyamine-binding proteins on leukaemic and solid-tumour cell types using a new polyamine photoprobe.
    The Biochemical journal, 1997, Dec-15, Volume: 328 ( Pt 3)

    Topics: Animals; Binding, Competitive; Biological Transport; Carrier Proteins; Cell Membrane; Cross-Linking

1997
Dimethylsilane polyamines: cytostatic compounds with potentials as anticancer drugs.
    Anti-cancer drug design, 1997, Volume: 12, Issue:8

    Topics: Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; CHO Cells; Cricetinae; DNA; Drug Screening As

1997
Effect of polyamine analogues on hypusine content in JURKAT T-cells.
    Journal of medicinal chemistry, 1998, Sep-24, Volume: 41, Issue:20

    Topics: Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; Biological Transport; Cell Divisio

1998
Effect of N8-acetylspermidine deacetylase inhibition on the growth of L1210 cells.
    Biochemical pharmacology, 1999, May-15, Volume: 57, Issue:10

    Topics: Amidohydrolases; Animals; Cell Division; Chromatography, High Pressure Liquid; Diamines; Drug Intera

1999
Novel approaches to polynuclear platinum pro-drugs. Selective release of cytotoxic platinum-spermidine species through hydrolytic cleavage of carbamates.
    Inorganic chemistry, 2001, Nov-19, Volume: 40, Issue:24

    Topics: Animals; Antineoplastic Agents; Carbamates; Catalysis; Chromatography, High Pressure Liquid; Female;

2001
Granulocytic chalone is not a polyamine complex.
    Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1979, Volume: 31, Issue:6

    Topics: Animals; Bone Marrow; Granulocytes; Growth Inhibitors; Humans; Leukemia L1210; Leukemia, Experimenta

1979
Inhibitors of polyamine biosynthesis. 4. Effects of alpha-methyl-(+/-)-ornithine and methylglyoxal bis(guanylhydrazone) on growth and polyamine content of L1210 leukemic cells of mice.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:2

    Topics: Animals; Cell Division; Cells, Cultured; DNA, Neoplasm; Guanidines; Leukemia L1210; Mice; Mitoguazon

1977
Determination of diamines and polyamines in tissues by high-pressure liquid chromatography.
    Journal of chromatography, 1976, Sep-15, Volume: 124, Issue:2

    Topics: Animals; Brain Chemistry; Cells, Cultured; Chromatography, High Pressure Liquid; Dansyl Compounds; L

1976
Diacridines: bifunctional intercalators. II. The biological effects of putrescine, sperimidine and spermine diacridines on HeLa cells and on the L-1210 and P-388 leukemia cells.
    Biochimica et biophysica acta, 1976, Feb-05, Volume: 418, Issue:3

    Topics: Acridines; Animals; Cell Division; HeLa Cells; Leukemia L1210; Leukemia, Experimental; Mice; Protein

1976
Increased survival of L1210 leukemic mice by prevention of the utilization of extracellular polyamines. Studies using a polyamine-uptake mutant, antibiotics and a polyamine-deficient diet.
    Cancer letters, 1992, Sep-14, Volume: 66, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Biological Transport; Carbon Radioisotopes; Drug Resistance; Eflorni

1992
New S-adenosylmethionine decarboxylase inhibitors with potent antitumor activity.
    Cancer research, 1992, Sep-01, Volume: 52, Issue:17

    Topics: Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; Cell Division; DNA, Mitochondrial;

1992
Mechanism of spermidine uptake in cultured mammalian cells and its inhibition by some polyamine analogues.
    Pathobiology : journal of immunopathology, molecular and cellular biology, 1990, Volume: 58, Issue:3

    Topics: Amino Acids; Animals; Biological Transport; Calcimycin; Fibroblasts; Glioma; Gramicidin; Humans; Leu

1990
Selective cellular depletion of mitochondrial DNA by the polyamine analog N1,N12-bis(ethyl)spermine and its relationship to polyamine structure and function.
    Molecular pharmacology, 1991, Volume: 39, Issue:4

    Topics: Animals; Antineoplastic Agents; Blotting, Southern; Cell Division; Cell Line, Transformed; DNA; DNA

1991
Feedback regulation of ornithine decarboxylase expression. Studies using a polysomal run-off system.
    FEBS letters, 1990, Jan-15, Volume: 260, Issue:1

    Topics: Animals; Cell Line; Cell-Free System; Eflornithine; Feedback; Gene Expression Regulation, Enzymologi

1990
Dual mechanisms of inhibition of DNA synthesis by triciribine.
    Cancer research, 1990, Aug-15, Volume: 50, Issue:16

    Topics: Animals; Antineoplastic Agents; DNA Polymerase I; DNA Primase; DNA Replication; DNA, Neoplasm; Kinet

1990
Cellular characterization of a new irreversible inhibitor of S-adenosylmethionine decarboxylase and its use in determining the relative abilities of individual polyamines to sustain growth and viability of L1210 cells.
    The Biochemical journal, 1989, Apr-15, Volume: 259, Issue:2

    Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Cell Division; Cell Survival; Deoxyadenos

1989
Topological complexes between DNA and topoisomerase II and effects of polyamines.
    Biochemistry, 1989, Feb-07, Volume: 28, Issue:3

    Topics: Amsacrine; Animals; DNA Topoisomerases, Type II; DNA, Viral; Kinetics; Leukemia L1210; Mice; Protein

1989
Major increases in spermidine/spermine-N1-acetyltransferase activity by spermine analogues and their relationship to polyamine depletion and growth inhibition in L1210 cells.
    Cancer research, 1989, Nov-15, Volume: 49, Issue:22

    Topics: Acetyltransferases; Animals; Cell Division; Cell Line; Cell Survival; Dogs; Humans; Kinetics; Leukem

1989
Comparison and characterization of growth inhibition in L1210 cells by alpha-difluoromethylornithine, an inhibitor of ornithine decarboxylase, and N1,N8-bis(ethyl)spermidine, an apparent regulator of the enzyme.
    Cancer research, 1986, Volume: 46, Issue:12 Pt 1

    Topics: Adenosylmethionine Decarboxylase; Alkynes; Animals; Cells, Cultured; Diamines; Eflornithine; Leukemi

1986
Regulation of ornithine decarboxylase mRNA translation by polyamines. Studies using a cell-free system and a cell line with an amplified ornithine decarboxylase gene.
    The Journal of biological chemistry, 1988, Mar-05, Volume: 263, Issue:7

    Topics: Animals; Cell-Free System; Eflornithine; Gene Amplification; Leukemia L1210; Mice; Mutation; Ornithi

1988
Effect of inhibitors of S-adenosylmethionine decarboxylase on the contents of ornithine decarboxylase and S-adenosylmethionine decarboxylase in L1210 cells.
    The Biochemical journal, 1988, Aug-15, Volume: 254, Issue:1

    Topics: Adenosine; Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Deoxyadenosines; Leukemia L121

1988
Enzyme regulation as an approach to interference with polyamine biosynthesis--an alternative to enzyme inhibition.
    Advances in enzyme regulation, 1988, Volume: 27

    Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Cell Division; Leukemia L1210; Mice; Orni

1988
Mechanism of antitumor activity of norspermidine, a structural homologue of spermidine.
    Advances in experimental medicine and biology, 1988, Volume: 250

    Topics: Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; DNA, Neoplasm; HeLa Cells; Leukemi

1988
Relative abilities of bis(ethyl) derivatives of putrescine, spermidine, and spermine to regulate polyamine biosynthesis and inhibit L1210 leukemia cell growth.
    Cancer research, 1987, Jun-01, Volume: 47, Issue:11

    Topics: Adenosylmethionine Decarboxylase; Animals; Biological Transport; Cell Division; Leukemia L1210; Mice

1987
Synthesis and antitumor activity of spergualin analogues. II. Chemical modification of the spermidine moiety.
    The Journal of antibiotics, 1987, Volume: 40, Issue:9

    Topics: Animals; Antibiotics, Antineoplastic; Guanidines; Leukemia L1210; Male; Mice; Spermidine; Structure-

1987
Biological properties of N4- and N1,N8-spermidine derivatives in cultured L1210 leukemia cells.
    Cancer research, 1985, Volume: 45, Issue:5

    Topics: Animals; Cells, Cultured; Eflornithine; Kinetics; Leukemia L1210; Mice; Ornithine; Polyamines; Sperm

1985
Characterization of L1210 cell growth inhibition by the bacterial iron chelators parabactin and compound II.
    Cancer research, 1985, Volume: 45, Issue:10

    Topics: Animals; Cell Cycle; DNA; Iron Chelating Agents; Leukemia L1210; Mice; Oxazoles; Ribonucleoside Diph

1985
Synthesis and antitumor activity of spergualin analogues. I. Chemical modification of 7-guanidino-3-hydroxyacyl moiety.
    The Journal of antibiotics, 1985, Volume: 38, Issue:7

    Topics: Animals; Antibiotics, Antineoplastic; Carboxylic Acids; Catalysis; Drug Evaluation, Preclinical; Gua

1985
Depression of polyamine synthesis in L1210 leukemic mice during treatment with a potent antileukemic agent, 5-azacytidine.
    Cancer research, 1973, Volume: 33, Issue:1

    Topics: Animals; Antineoplastic Agents; Azacitidine; Carboxy-Lyases; Cytidine; Depression, Chemical; Enzyme

1973
Polyamines and transfer RNA-methylation in mouse leukemic cells.
    Physiological chemistry and physics, 1972, Volume: 4, Issue:1

    Topics: Animals; Binding Sites; Carbon Radioisotopes; Chromatography, Gel; Chromatography, Paper; Chromatogr

1972
Stimulation of ornithine decarboxylase activity and inhibition of S-adenosyl-L-methionine decarboxylase activity in leukaemic mice by methylglyoxal bis(guanylhydrazone).
    The Biochemical journal, 1973, Volume: 136, Issue:4

    Topics: Adenosine; Amidines; Animals; Carboxy-Lyases; Depression, Chemical; Glyoxal; Hydrazones; Leukemia L1

1973
Effects of methylglyoxal-bis(guanylhydrazone) on polyamine metabolism in spleens of mice with disseminated L1210 lymphoid leukemia.
    Cancer research, 1974, Volume: 34, Issue:4

    Topics: Amidines; Animals; Antineoplastic Agents; Carboxy-Lyases; Glyoxal; Hydrazones; Leukemia L1210; Male;

1974
Effects of methotrexate and cytosine arabinoside on polyamine metabolism in a mouse L1210 leukemia.
    Cancer research, 1972, Volume: 32, Issue:11

    Topics: Animals; Carbon Isotopes; Carboxy-Lyases; Cytarabine; Leukemia L1210; Methotrexate; Mice; Mice, Inbr

1972