spermidine has been researched along with Leishmaniasis, Visceral in 3 studies
Leishmaniasis, Visceral: A chronic disease caused by LEISHMANIA DONOVANI and transmitted by the bite of several sandflies of the genera Phlebotomus and Lutzomyia. It is commonly characterized by fever, chills, vomiting, anemia, hepatosplenomegaly, leukopenia, hypergammaglobulinemia, emaciation, and an earth-gray color of the skin. The disease is classified into three main types according to geographic distribution: Indian, Mediterranean (or infantile), and African.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Trypanothione is a unique and essential redox metabolite of trypanosomatid parasites, the biosynthetic pathway of which is regarded as a promising target for antiparasitic drugs." | 1.40 | Genetic and chemical analyses reveal that trypanothione synthetase but not glutathionylspermidine synthetase is essential for Leishmania infantum. ( Benítez, D; Castro, H; Comini, MA; Flohé, L; Gomes-Alves, AG; Jaeger, T; Passos, J; Sousa, AF; Stuhlmann, F; Tomás, AM, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jagu, E | 1 |
| Pomel, S | 1 |
| Diez-Martinez, A | 1 |
| Ramiandrasoa, F | 1 |
| Krauth-Siegel, RL | 1 |
| Pethe, S | 1 |
| Blonski, C | 1 |
| Labruère, R | 1 |
| Loiseau, PM | 1 |
| Singh, S | 1 |
| Kumari, E | 1 |
| Bhardwaj, R | 1 |
| Kumar, R | 1 |
| Dubey, VK | 1 |
| Sousa, AF | 1 |
| Gomes-Alves, AG | 1 |
| Benítez, D | 1 |
| Comini, MA | 1 |
| Flohé, L | 1 |
| Jaeger, T | 1 |
| Passos, J | 1 |
| Stuhlmann, F | 1 |
| Tomás, AM | 1 |
| Castro, H | 1 |
3 other studies available for spermidine and Leishmaniasis, Visceral
| Article | Year |
|---|---|
Synthesis and in vitro antikinetoplastid activity of polyamine-hydroxybenzotriazole conjugates.
Topics: Animals; Antiprotozoal Agents; Humans; Leishmania donovani; Leishmaniasis, Visceral; NADH, NADPH Oxi | 2017 |
Molecular events leading to death of Leishmania donovani under spermidine starvation after hypericin treatment.
Topics: Adenosine Triphosphate; Anthracenes; Gene Expression Regulation; Humans; Leishmania donovani; Leishm | 2017 |
Genetic and chemical analyses reveal that trypanothione synthetase but not glutathionylspermidine synthetase is essential for Leishmania infantum.
Topics: Amide Synthases; Animals; Antiprotozoal Agents; Gene Knockout Techniques; Glutathione; Leishmania in | 2014 |