Page last updated: 2024-10-20

spermidine and Ischemia

spermidine has been researched along with Ischemia in 6 studies

Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.

Research Excerpts

ExcerptRelevanceReference
"Spermidine is a naturally occurring polyamine, and its dietary supplementation has exhibited distinct anti-aging and healthy lifespan-extending effects in various species such as yeast, worms, flies, and mice."5.91Spermidine improves angiogenic capacity of senescent endothelial cells, and enhances ischemia-induced neovascularization in aged mice. ( Ikeda, K; Katayama, A; Matoba, S; Ueno, D; Urata, R; Yamazaki, E, 2023)
"In liver cells recovering from reversible ischemia the increase in RNA synthesis by isolated nuclei is preceded by activation of ornithine decarboxylase, leading in turn to an increase in putrescine concentration."3.66Relationships between polyamine metabolism and RNA synthesis in post-ischemic liver cell repair. ( Bernelli-Zazzera, A; Cairo, G; Ferioli, ME; Scalabrino, G; Schiaffonati, L, 1980)
"Spermidine is a naturally occurring polyamine, and its dietary supplementation has exhibited distinct anti-aging and healthy lifespan-extending effects in various species such as yeast, worms, flies, and mice."1.91Spermidine improves angiogenic capacity of senescent endothelial cells, and enhances ischemia-induced neovascularization in aged mice. ( Ikeda, K; Katayama, A; Matoba, S; Ueno, D; Urata, R; Yamazaki, E, 2023)
"Thymoquinone treatment caused the reversal of I/R-induced changes in MDA as well as GST and SOD activity."1.37Effect of thymoquinone on hepatorenal dysfunction and alteration of CYP3A1 and spermidine/spermine N-1-acetyl-transferase gene expression induced by renal ischaemia-reperfusion in rats. ( Awad, AS; Kamel, R; Sherief, MA, 2011)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's1 (16.67)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Ueno, D1
Ikeda, K1
Yamazaki, E1
Katayama, A1
Urata, R1
Matoba, S1
Awad, AS1
Kamel, R1
Sherief, MA1
Weiss, TS1
Bernhardt, G1
Buschauer, A1
Thasler, WE1
Dolgner, D1
Zirngibl, H1
Jauch, KW1
Morrison, B1
Pringle, AK1
McManus, T1
Ellard, J1
Bradley, M1
Signorelli, F1
Iannotti, F1
Sundstrom, LE1
Ferioli, ME1
Schiaffonati, L1
Scalabrino, G1
Cairo, G1
Bernelli-Zazzera, A1
Guzman, C1
MacLeod, RJ1
Hamilton, JR1

Other Studies

6 other studies available for spermidine and Ischemia

ArticleYear
Spermidine improves angiogenic capacity of senescent endothelial cells, and enhances ischemia-induced neovascularization in aged mice.
    Scientific reports, 2023, 05-23, Volume: 13, Issue:1

    Topics: Animals; Cardiovascular Physiological Phenomena; Endothelial Cells; Ischemia; Mice; Neovascularizati

2023
Effect of thymoquinone on hepatorenal dysfunction and alteration of CYP3A1 and spermidine/spermine N-1-acetyl-transferase gene expression induced by renal ischaemia-reperfusion in rats.
    The Journal of pharmacy and pharmacology, 2011, Volume: 63, Issue:8

    Topics: Acetyltransferases; Alanine Transaminase; Animals; Antioxidants; Benzoquinones; Creatinine; Cytochro

2011
Polyamine levels of human colorectal adenocarcinomas are correlated with tumor stage and grade.
    International journal of colorectal disease, 2002, Volume: 17, Issue:6

    Topics: Acetyltransferases; Adenocarcinoma; Aged; Biomarkers, Tumor; Chromatography, Liquid; Colorectal Neop

2002
L-arginyl-3,4-spermidine is neuroprotective in several in vitro models of neurodegeneration and in vivo ischaemia without suppressing synaptic transmission.
    British journal of pharmacology, 2002, Volume: 137, Issue:8

    Topics: Animals; Arginine; Cell Death; Cell Hypoxia; Cells, Cultured; Hippocampus; Ischemia; Neurodegenerati

2002
Relationships between polyamine metabolism and RNA synthesis in post-ischemic liver cell repair.
    Journal of cellular physiology, 1980, Volume: 103, Issue:1

    Topics: Adenosylmethionine Decarboxylase; Animals; Hypophysectomy; Ischemia; Liver; Ornithine Decarboxylase;

1980
Failure of ornithine decarboxylase inhibition to alter small intestinal epithelial repair after transient segmental ischaemia.
    Gut, 1988, Volume: 29, Issue:7

    Topics: Animals; Eflornithine; Intestinal Mucosa; Intestine, Small; Ischemia; Ornithine Decarboxylase Inhibi

1988