spermidine has been researched along with Idiopathic Parkinson Disease in 8 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " Our studies showed that osmotic toxicity had an adverse effect on α-synuclein aggregation, autophagic puncta, lipid content and oxidative stress." | 1.48 | Osmotic stress induced toxicity exacerbates Parkinson's associated effects via dysregulation of autophagy in transgenic C. elegans model. ( Jadiya, P; Mir, SS; Nazir, A, 2018) |
| "Spermidine treatment also attenuated oxidative stress, neuroinflammation and restored striatal neurochemistry." | 1.48 | Neuroprotective potential of spermidine against rotenone induced Parkinson's disease in rats. ( Deshmukh, R; Kumar, P; Sharma, S, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 5 (62.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Vrijsen, S | 1 |
| Houdou, M | 1 |
| Cascalho, A | 1 |
| Eggermont, J | 1 |
| Vangheluwe, P | 1 |
| Jadiya, P | 1 |
| Mir, SS | 1 |
| Nazir, A | 1 |
| Sharma, S | 1 |
| Kumar, P | 1 |
| Deshmukh, R | 1 |
| Büttner, S | 1 |
| Broeskamp, F | 1 |
| Sommer, C | 1 |
| Markaki, M | 1 |
| Habernig, L | 1 |
| Alavian-Ghavanini, A | 1 |
| Carmona-Gutierrez, D | 1 |
| Eisenberg, T | 1 |
| Michael, E | 1 |
| Kroemer, G | 1 |
| Tavernarakis, N | 1 |
| Sigrist, SJ | 1 |
| Madeo, F | 1 |
| Paik, MJ | 1 |
| Ahn, YH | 1 |
| Lee, PH | 1 |
| Kang, H | 1 |
| Park, CB | 1 |
| Choi, S | 1 |
| Lee, G | 1 |
| De La Hera, DP | 1 |
| Corradi, GR | 1 |
| Adamo, HP | 1 |
| De Tezanos Pinto, F | 1 |
| Gomes-Trolin, C | 1 |
| Nygren, I | 1 |
| Aquilonius, SM | 1 |
| Askmark, H | 1 |
| Antony, T | 1 |
| Hoyer, W | 1 |
| Cherny, D | 1 |
| Heim, G | 1 |
| Jovin, TM | 1 |
| Subramaniam, V | 1 |
1 review available for spermidine and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
Polyamines in Parkinson's Disease: Balancing Between Neurotoxicity and Neuroprotection.
Topics: Animals; Humans; Mammals; Neuroprotection; Parkinson Disease; Parkinsonian Disorders; Polyamines; Sp | 2023 |
1 trial available for spermidine and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
Increased red blood cell polyamines in ALS and Parkinson's disease.
Topics: Amyotrophic Lateral Sclerosis; Biogenic Polyamines; Erythrocytes; Female; Humans; Levodopa; Male; Mi | 2002 |
6 other studies available for spermidine and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
Osmotic stress induced toxicity exacerbates Parkinson's associated effects via dysregulation of autophagy in transgenic C. elegans model.
Topics: alpha-Synuclein; Animals; Animals, Genetically Modified; Autophagy; Caenorhabditis elegans; Caenorha | 2018 |
Neuroprotective potential of spermidine against rotenone induced Parkinson's disease in rats.
Topics: Animals; Antioxidants; Dopamine; Dopaminergic Neurons; Neuroprotection; Neuroprotective Agents; Oxid | 2018 |
Spermidine protects against α-synuclein neurotoxicity.
Topics: alpha-Synuclein; Animals; Autophagy; Caenorhabditis elegans; Disease Models, Animal; Dopaminergic Ne | 2014 |
Polyamine patterns in the cerebrospinal fluid of patients with Parkinson's disease and multiple system atrophy.
Topics: Aged; Biomarkers; Cerebrospinal Fluid; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; M | 2010 |
Parkinson's disease-associated human P5B-ATPase ATP13A2 increases spermidine uptake.
Topics: Animals; CHO Cells; Cricetinae; Cricetulus; Endosomes; Humans; Kinetics; Lysosomes; Parkinson Diseas | 2013 |
Cellular polyamines promote the aggregation of alpha-synuclein.
Topics: alpha-Synuclein; Binding Sites; Circular Dichroism; Cloning, Molecular; Escherichia coli; Humans; Mi | 2003 |