spermidine has been researched along with Hypertension in 8 studies
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Polyamines (putrescine, spermidine and spermine) play an important role in the development of hypertension and in the expression of atrial natriuretic peptide (ANP), a cardiac hormone involved in the regulation of blood pressure." | 7.71 | Hypertension in normotensive and hypertensive rats by spermine ingestion. ( Li, S; Tipnis, UR, 2001) |
| "The aim was to investigate the involvement of polyamines in the development of cardiovascular hypertrophy in a rat angiotensin II infusion model of hypertension." | 7.69 | Role of polyamines in hypertension induced by angiotensin II. ( Hughes, AD; Ibrahim, J; Schachter, M; Sever, PS, 1995) |
| " We therefore tested the protective capacity of the natural autophagy inducer spermidine in animal models of aging and hypertension, which both represent major risk factors for the development of cardiovascular disease." | 3.85 | Dietary spermidine for lowering high blood pressure. ( Abdellatif, M; Carmona-Gutierrez, D; Dammbrueck, C; Dengjel, J; Eisenberg, T; Gross, AS; Harger, A; Herbst, V; Kiechl, S; Kroemer, G; Linke, WA; Madeo, F; Magnes, C; Mühlfeld, C; Pendl, T; Pieber, TR; Pietrocola, F; Ruckenstuhl, C; Sadoshima, J; Schipke, J; Schmidt, A; Schroeder, S; Sedej, S; Sigrist, SJ; Stekovic, S; Zimmermann, A, 2017) |
| "Polyamines (putrescine, spermidine and spermine) play an important role in the development of hypertension and in the expression of atrial natriuretic peptide (ANP), a cardiac hormone involved in the regulation of blood pressure." | 3.71 | Hypertension in normotensive and hypertensive rats by spermine ingestion. ( Li, S; Tipnis, UR, 2001) |
| "The aim was to investigate the involvement of polyamines in the development of cardiovascular hypertrophy in a rat angiotensin II infusion model of hypertension." | 3.69 | Role of polyamines in hypertension induced by angiotensin II. ( Hughes, AD; Ibrahim, J; Schachter, M; Sever, PS, 1995) |
| "Hydralazine is an antihypertensive drug that elicits andti-nuclear antibodies in patients as an adverse effect." | 1.29 | Triplex-DNA stabilization by hydralazine and the presence of anti-(triplex DNA) antibodies in patients treated with hydralazine. ( Adams, LE; Hess, EV; Seibold, JR; Thomas, TJ, 1995) |
| " The effects of chronic administration of alpha-difluoromethylornithine, a specific irreversible inhibitor of ornithine decarboxylase and thus polyamine biosynthesis, on vascular polyamine contents, structure, and function as well as the development of hypertension was studied." | 1.28 | Polyamines, vascular smooth muscle, and deoxycorticosterone acetate-salt hypertension. ( Newman, PS; Olson, JW; Soltis, EE, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Eisenberg, T | 1 |
| Abdellatif, M | 1 |
| Zimmermann, A | 1 |
| Schroeder, S | 1 |
| Pendl, T | 1 |
| Harger, A | 1 |
| Stekovic, S | 1 |
| Schipke, J | 1 |
| Magnes, C | 1 |
| Schmidt, A | 1 |
| Ruckenstuhl, C | 1 |
| Dammbrueck, C | 1 |
| Gross, AS | 1 |
| Herbst, V | 1 |
| Carmona-Gutierrez, D | 1 |
| Pietrocola, F | 1 |
| Pieber, TR | 1 |
| Sigrist, SJ | 1 |
| Linke, WA | 1 |
| Mühlfeld, C | 1 |
| Sadoshima, J | 1 |
| Dengjel, J | 1 |
| Kiechl, S | 1 |
| Kroemer, G | 1 |
| Sedej, S | 1 |
| Madeo, F | 1 |
| Burke, M | 1 |
| Neufeld, E | 1 |
| Goldberg, S | 1 |
| Chayen, R | 1 |
| Thomas, TJ | 1 |
| Seibold, JR | 1 |
| Adams, LE | 1 |
| Hess, EV | 1 |
| Ibrahim, J | 1 |
| Schachter, M | 1 |
| Hughes, AD | 1 |
| Sever, PS | 1 |
| Maione, S | 1 |
| Berrino, L | 1 |
| Pizzirusso, A | 1 |
| Leyva, J | 1 |
| Filippelli, A | 1 |
| Vitagliano, S | 1 |
| Rossi, F | 1 |
| Tipnis, UR | 1 |
| Li, S | 1 |
| Sohn, HS | 1 |
| Park, YN | 1 |
| Lee, SR | 1 |
| Soltis, EE | 1 |
| Newman, PS | 1 |
| Olson, JW | 1 |
8 other studies available for spermidine and Hypertension
| Article | Year |
|---|---|
Dietary spermidine for lowering high blood pressure.
Topics: Animals; Humans; Hypertension; Mice, Inbred C57BL; Models, Biological; Rats, Inbred Dahl; Spermidine | 2017 |
Lack of inhibition of diamine oxidase during hydralazine therapy.
Topics: Amine Oxidase (Copper-Containing); Cadaverine; Humans; Hydralazine; Hypertension; Male; Putrescine; | 1984 |
Triplex-DNA stabilization by hydralazine and the presence of anti-(triplex DNA) antibodies in patients treated with hydralazine.
Topics: Adolescent; Adult; Antibodies, Antinuclear; Antihypertensive Agents; Circular Dichroism; DNA; Female | 1995 |
Role of polyamines in hypertension induced by angiotensin II.
Topics: Angiotensin II; Animals; Aorta; Cardiomegaly; Disease Models, Animal; Heart Ventricles; Hypertension | 1995 |
Effects of the polyamine spermidine on NMDA-induced arterial hypertension in freely moving rats.
Topics: Animals; Biguanides; Blood Pressure; Drug Synergism; Hypertension; Male; Microinjections; N-Methylas | 1994 |
Hypertension in normotensive and hypertensive rats by spermine ingestion.
Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Heart Ventricles; Hypertension; Myocardium; Poly | 2001 |
Effect of immobilization stress on brain polyamine levels in spontaneously hypertensive and Wistar-Kyoto rats.
Topics: Acute Disease; Animals; Biogenic Polyamines; Brain; Chronic Disease; Frontal Lobe; Hippocampus; Hype | 2002 |
Polyamines, vascular smooth muscle, and deoxycorticosterone acetate-salt hypertension.
Topics: Acetylcholine; Animals; Aorta; Arteries; Blood Pressure; Body Weight; Desoxycorticosterone; Dose-Res | 1991 |