spermidine has been researched along with Hypertension, Pulmonary in 5 studies
Hypertension, Pulmonary: Increased VASCULAR RESISTANCE in the PULMONARY CIRCULATION, usually secondary to HEART DISEASES or LUNG DISEASES.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In support of this contention, we have shown in rat models of monocrotaline (MCT)- and chronic hypoxia-induced pulmonary hypertension that whole-lung polyamine contents are elevated and that blockade of polyamine synthesis forestalls development of hypertensive pulmonary vascular remodeling and sustained pulmonary hypertension." | 7.67 | Polyamine content in pulmonary arteries from rats with monocrotaline-induced pulmonary hypertension. ( Gillespie, MN; Olson, JW; Orlinska, U, 1988) |
| "Lung putrescine levels were increased from days 7 through 21, and both spermidine and spermine were first elevated at day 10 following MCT administration." | 5.27 | Polyamines and the development of monocrotaline-induced pulmonary hypertension. ( Altiere, RJ; Gillespie, MN; Hacker, AD; Olson, JW, 1984) |
| " In support of this contention, we have shown in rat models of monocrotaline (MCT)- and chronic hypoxia-induced pulmonary hypertension that whole-lung polyamine contents are elevated and that blockade of polyamine synthesis forestalls development of hypertensive pulmonary vascular remodeling and sustained pulmonary hypertension." | 3.67 | Polyamine content in pulmonary arteries from rats with monocrotaline-induced pulmonary hypertension. ( Gillespie, MN; Olson, JW; Orlinska, U, 1988) |
| "Putrescine efflux also was altered by hypoxic exposure; T1/2 for loss of diamine from a slowly effluxing pool was increased from 60." | 1.28 | Mechanisms of lung polyamine accumulation in chronic hypoxic pulmonary hypertension. ( Gillespie, MN; Kostenbauder, HB; Olson, JW; Shiao, RT, 1990) |
| "Lung putrescine levels were increased from days 7 through 21, and both spermidine and spermine were first elevated at day 10 following MCT administration." | 1.27 | Polyamines and the development of monocrotaline-induced pulmonary hypertension. ( Altiere, RJ; Gillespie, MN; Hacker, AD; Olson, JW, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, Q | 1 |
| Zhou, X | 1 |
| Wang, Y | 1 |
| Hu, Y | 1 |
| Olson, JW | 4 |
| Hacker, AD | 1 |
| Altiere, RJ | 1 |
| Gillespie, MN | 4 |
| Babal, P | 1 |
| Ruchko, M | 1 |
| Ault-Ziel, K | 1 |
| Cronenberg, L | 1 |
| Shiao, RT | 1 |
| Kostenbauder, HB | 1 |
| Orlinska, U | 1 |
5 other studies available for spermidine and Hypertension, Pulmonary
| Article | Year |
|---|---|
LncRNA GAS5 promotes spermidine‑induced autophagy through the miRNA‑31‑5p/NAT8L axis in pulmonary artery endothelial cells of patients with CTEPH.
Topics: Acetyltransferases; Animals; Autophagy; Endothelial Cells; Hypertension, Pulmonary; MicroRNAs; Pulmo | 2022 |
Polyamines and the development of monocrotaline-induced pulmonary hypertension.
Topics: Adenosylmethionine Decarboxylase; Animals; Blood Pressure; Eflornithine; Heart Ventricles; Hypertens | 1984 |
Regulation of ornithine decarboxylase and polyamine import by hypoxia in pulmonary artery endothelial cells.
Topics: Animals; Blotting, Western; Carbon Radioisotopes; Cattle; Cells, Cultured; Endothelium, Vascular; En | 2002 |
Mechanisms of lung polyamine accumulation in chronic hypoxic pulmonary hypertension.
Topics: Animals; Blood Pressure; Cardiomegaly; Disease Models, Animal; Hypertension, Pulmonary; Hypoxia; Liv | 1990 |
Polyamine content in pulmonary arteries from rats with monocrotaline-induced pulmonary hypertension.
Topics: Animals; Hypertension, Pulmonary; Lung; Male; Monocrotaline; Polyamines; Pulmonary Artery; Putrescin | 1988 |