spermidine has been researched along with Fatty Liver, Nonalcoholic in 8 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Spermidine serves as an oral supplement to attenuate obesity and metabolic disorders through hypothalamus-dependent or -independent BAT activation and skeletal muscle adaptation." | 8.02 | Oral Spermidine Targets Brown Fat and Skeletal Muscle to Mitigate Diet-Induced Obesity and Metabolic Disorders. ( Guo, C; Jia, Y; Jie, H; Li, R; Li, Y; Mao, H; Tao, Y; Wang, D; Wang, Q; Yin, J; Zhang, L; Zhao, J; Zhou, Z; Zhu, F, 2021) |
| "In this study, treatment of high-fat diet-induced obesity (DIO) C57BL/6J mice with spermidine decreased body weight and subcutaneous and visceral fat content, reversed the apparent hepatosteatosis, and reduced hepatic intracellular and serum triglyceride and total cholesterol concentrations." | 7.88 | Spermidine ameliorates non-alcoholic fatty liver disease through regulating lipid metabolism via AMPK. ( Bi, Y; Du, Y; Fang, F; Gao, M; Li, C; Li, M; Liu, X; Xie, X; Zhao, W, 2018) |
| " Based on severity of liver fibrosis, body composition and body weight, the mice from both dietary groups were randomized into another two groups: half receiving 3 mM spermidine in drinking water, half normal water for subsequent 12 weeks." | 4.31 | Restoring polyamine levels by supplementation of spermidine modulates hepatic immune landscape in murine model of NASH. ( Cohen, TS; Ford, M; Lasky, G; Oldham, S; Rhodes, CJ; Rivera, C; Sellman, BR; Szydlowska, M, 2023) |
| "Spermidine serves as an oral supplement to attenuate obesity and metabolic disorders through hypothalamus-dependent or -independent BAT activation and skeletal muscle adaptation." | 4.02 | Oral Spermidine Targets Brown Fat and Skeletal Muscle to Mitigate Diet-Induced Obesity and Metabolic Disorders. ( Guo, C; Jia, Y; Jie, H; Li, R; Li, Y; Mao, H; Tao, Y; Wang, D; Wang, Q; Yin, J; Zhang, L; Zhao, J; Zhou, Z; Zhu, F, 2021) |
| "In this study, treatment of high-fat diet-induced obesity (DIO) C57BL/6J mice with spermidine decreased body weight and subcutaneous and visceral fat content, reversed the apparent hepatosteatosis, and reduced hepatic intracellular and serum triglyceride and total cholesterol concentrations." | 3.88 | Spermidine ameliorates non-alcoholic fatty liver disease through regulating lipid metabolism via AMPK. ( Bi, Y; Du, Y; Fang, F; Gao, M; Li, C; Li, M; Liu, X; Xie, X; Zhao, W, 2018) |
| "Spermidine is a natural polyamine that has health benefits and extends life span in several species." | 1.72 | Spermidine-mediated hypusination of translation factor EIF5A improves mitochondrial fatty acid oxidation and prevents non-alcoholic steatohepatitis progression. ( Cook, SA; Diehl, AM; Ho, JP; Pang, J; Petretto, E; Shekeran, SG; Singh, BK; Suzuki, A; Tripathi, M; Widjaja, AA; Yen, PM; Zhou, J, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 6 (75.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ni, Y | 1 |
| Hu, Y | 1 |
| Lou, X | 1 |
| Rong, N | 1 |
| Liu, F | 1 |
| Yang, C | 1 |
| Zheng, A | 1 |
| Yang, S | 1 |
| Bao, J | 1 |
| Fu, Z | 1 |
| Zhou, J | 1 |
| Pang, J | 1 |
| Tripathi, M | 1 |
| Ho, JP | 1 |
| Widjaja, AA | 1 |
| Shekeran, SG | 1 |
| Cook, SA | 1 |
| Suzuki, A | 1 |
| Diehl, AM | 1 |
| Petretto, E | 1 |
| Singh, BK | 1 |
| Yen, PM | 1 |
| Preethy, S | 1 |
| Ikewaki, N | 1 |
| Levy, GA | 1 |
| Raghavan, K | 1 |
| Dedeepiya, VD | 1 |
| Yamamoto, N | 1 |
| Srinivasan, S | 1 |
| Ranganathan, N | 1 |
| Iwasaki, M | 1 |
| Senthilkumar, R | 1 |
| Abraham, SJK | 1 |
| Szydlowska, M | 1 |
| Lasky, G | 1 |
| Oldham, S | 1 |
| Rivera, C | 1 |
| Ford, M | 1 |
| Sellman, BR | 1 |
| Rhodes, CJ | 1 |
| Cohen, TS | 1 |
| Sasaki, GY | 1 |
| Li, J | 1 |
| Cichon, MJ | 1 |
| Kopec, RE | 1 |
| Bruno, RS | 1 |
| Wang, D | 1 |
| Yin, J | 1 |
| Zhou, Z | 1 |
| Tao, Y | 1 |
| Jia, Y | 1 |
| Jie, H | 1 |
| Zhao, J | 1 |
| Li, R | 1 |
| Li, Y | 1 |
| Guo, C | 1 |
| Zhu, F | 1 |
| Mao, H | 1 |
| Zhang, L | 1 |
| Wang, Q | 1 |
| Gao, M | 1 |
| Zhao, W | 1 |
| Li, C | 1 |
| Xie, X | 1 |
| Li, M | 1 |
| Bi, Y | 1 |
| Fang, F | 1 |
| Du, Y | 1 |
| Liu, X | 1 |
| Bonhoure, N | 1 |
| Byrnes, A | 1 |
| Moir, RD | 1 |
| Hodroj, W | 1 |
| Preitner, F | 1 |
| Praz, V | 1 |
| Marcelin, G | 1 |
| Chua, SC | 1 |
| Martinez-Lopez, N | 1 |
| Singh, R | 1 |
| Moullan, N | 1 |
| Auwerx, J | 1 |
| Willemin, G | 1 |
| Shah, H | 1 |
| Hartil, K | 1 |
| Vaitheesvaran, B | 1 |
| Kurland, I | 1 |
| Hernandez, N | 1 |
| Willis, IM | 1 |
8 other studies available for spermidine and Fatty Liver, Nonalcoholic
| Article | Year |
|---|---|
Spermidine Ameliorates Nonalcoholic Steatohepatitis through Thyroid Hormone-Responsive Protein Signaling and the Gut Microbiota-Mediated Metabolism of Bile Acids.
Topics: Animals; Bile Acids and Salts; Fibrosis; Gastrointestinal Microbiome; Humans; Inflammation; Lipid Me | 2022 |
Spermidine-mediated hypusination of translation factor EIF5A improves mitochondrial fatty acid oxidation and prevents non-alcoholic steatohepatitis progression.
Topics: Animals; Fatty Acids; Lysine; Mice; Mitochondria; Non-alcoholic Fatty Liver Disease; Peptide Initiat | 2022 |
Two unique biological response-modifier glucans beneficially regulating gut microbiota and faecal metabolome in a non-alcoholic steatohepatitis animal model, with potential applications in human health and disease.
Topics: Animals; Anti-Inflammatory Agents; Disease Models, Animal; Firmicutes; Fructose; Gastrointestinal Mi | 2022 |
Restoring polyamine levels by supplementation of spermidine modulates hepatic immune landscape in murine model of NASH.
Topics: Animals; Body Weight; Diet, High-Fat; Dietary Supplements; Disease Models, Animal; Humans; Male; Mic | 2023 |
Catechin-Rich Green Tea Extract and the Loss-of-TLR4 Signaling Differentially Alter the Hepatic Metabolome in Mice with Nonalcoholic Steatohepatitis.
Topics: Acetyl Coenzyme A; Animals; Arginine; Bile Acids and Salts; Catechin; Dietary Supplements; Genotype; | 2021 |
Oral Spermidine Targets Brown Fat and Skeletal Muscle to Mitigate Diet-Induced Obesity and Metabolic Disorders.
Topics: Adipose Tissue, Brown; Administration, Oral; Animals; Diet, High-Fat; Hypothalamus; Insulin Resistan | 2021 |
Spermidine ameliorates non-alcoholic fatty liver disease through regulating lipid metabolism via AMPK.
Topics: AMP-Activated Protein Kinases; Animals; Body Weight; Cells, Cultured; Diet, High-Fat; Fatty Acid Syn | 2018 |
Loss of the RNA polymerase III repressor MAF1 confers obesity resistance.
Topics: Animals; Autophagy; Eating; Energy Metabolism; Lipid Metabolism; Longevity; Mice, Inbred C57BL; Mice | 2015 |