spermidine has been researched along with DDPAC in 1 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " We have tested the therapeutic potential of rapamycin, an inhibitor of the mammalian target of rapamycin (mTOR) and three other autophagy activators (spermidine, carbamazepine, and tamoxifen) in a FTLD-U mouse model with TDP-43 proteinopathies." | 3.78 | Autophagy activators rescue and alleviate pathogenesis of a mouse model with proteinopathies of the TAR DNA-binding protein 43. ( Guo, BS; Liu, YC; Shen, CK; Tsai, KJ; Wang, IF; Wu, CC; Yang, CH, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, IF | 1 |
| Guo, BS | 1 |
| Liu, YC | 1 |
| Wu, CC | 1 |
| Yang, CH | 1 |
| Tsai, KJ | 1 |
| Shen, CK | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Rapamycin (Sirolimus) Treatment for Amyotrophic Lateral Sclerosis[NCT03359538] | Phase 2 | 63 participants (Actual) | Interventional | 2017-09-19 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 other study available for spermidine and DDPAC
| Article | Year |
|---|---|
Autophagy activators rescue and alleviate pathogenesis of a mouse model with proteinopathies of the TAR DNA-binding protein 43.
Topics: Analysis of Variance; Animals; Autophagy; Blotting, Western; Carbamazepine; Caspase 3; Fluorometry; | 2012 |