spermidine has been researched along with Cystic Fibrosis in 14 studies
Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Free and conjugated [14C]spermidine were measured in plasma samples from normal individuals and cystic fibrosis patients." | 7.66 | Cystic fibrosis: decreased conjugation and excretion of [14C]spermidine. ( Beckerman, RC; Durie, BG; Rosenblum, MG; Russell, DH; Taussig, LM, 1978) |
| "Previous studies have shown an abnormality of the spermidine-to-spermine (Spd/Spm) ratio in whole blood of cystic fibrosis homo-and heterozygotes." | 7.65 | Distribution of spermidine and spermine in blood from cystic fibrosis patients and control subjects. ( Cohen, LF; Farrell, PM; Lundgren, DW, 1976) |
| "Serum putrescine (Pu), spermidine (Sd), spermine (Sp), and plasma diamine oxidase ativity (DAO) were determined in cystic fibrosis (CF) homozygotes and heterozygotes plus age-matched controls." | 3.66 | Age-related abnormalities of circulating polyamines and diamine oxidase activity in cystic fibrosis heterozygotes and homozygotes. ( Baylin, SB; Lockwood, DH; Marton, LJ; Rosenstein, BJ, 1980) |
| "Children with cystic fibrosis excreted elevated urinary levels of all three polyamines--putrescine, spermidine, and spermine." | 3.66 | Altered polyamine metabolism in cystic fibrosis. ( Barnett, DR; Beckerman, RC; Durie, BG; Rosenblum, MG; Russell, DH; Taussig, LM, 1979) |
| "Free and conjugated [14C]spermidine were measured in plasma samples from normal individuals and cystic fibrosis patients." | 3.66 | Cystic fibrosis: decreased conjugation and excretion of [14C]spermidine. ( Beckerman, RC; Durie, BG; Rosenblum, MG; Russell, DH; Taussig, LM, 1978) |
| "Previous studies have shown an abnormality of the spermidine-to-spermine (Spd/Spm) ratio in whole blood of cystic fibrosis homo-and heterozygotes." | 3.65 | Distribution of spermidine and spermine in blood from cystic fibrosis patients and control subjects. ( Cohen, LF; Farrell, PM; Lundgren, DW, 1976) |
| "Increased blood levels of spermidine and an increased spermidine/spermine ratio is documented in 31 patients with cystic fibrosis (CF)." | 3.65 | Polyamine metabolism in cystic fibrosis. ( Frias, J; Rennert, OM; Shukla, JB, 1976) |
| "The polyamines, spermidine and spermine, have been measured in whole blood extracts from control volunteers, patients with cystic fibrosis, and obligate cystic fibrosis heterozygotes." | 3.65 | Polyamine alterations in blood of male homozygotes and heterozygotes for cystic fibrosis. ( Di Sant'Agnese, PA; Farrell, PM; Lundgren, DW, 1975) |
| "Spermidine was elevated in lungs during P." | 1.72 | Pseudomonas aeruginosa utilizes the host-derived polyamine spermidine to facilitate antimicrobial tolerance. ( Cox, AA; Fothergill, JL; Green, AE; Hasan, CM; Jones, T; Kadioglu, A; Neill, DR; Pottenger, S; White, JS; Winstanley, C; Wright, MH, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (92.86) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Hasan, CM | 1 |
| Pottenger, S | 1 |
| Green, AE | 1 |
| Cox, AA | 1 |
| White, JS | 1 |
| Jones, T | 1 |
| Winstanley, C | 1 |
| Kadioglu, A | 1 |
| Wright, MH | 1 |
| Neill, DR | 1 |
| Fothergill, JL | 1 |
| Theoharides, TC | 1 |
| Russell, DH | 3 |
| Baylin, SB | 1 |
| Rosenstein, BJ | 1 |
| Marton, LJ | 1 |
| Lockwood, DH | 1 |
| Rosenblum, MG | 2 |
| Beckerman, RC | 2 |
| Durie, BG | 2 |
| Taussig, LM | 2 |
| Barnett, DR | 1 |
| Wright, RK | 1 |
| Buehler, BA | 1 |
| Schott, SN | 1 |
| Rennert, OM | 2 |
| Gahl, WA | 1 |
| Changus, JE | 1 |
| Pitot, HC | 1 |
| Cohen, LF | 1 |
| Lundgren, DW | 2 |
| Farrell, PM | 2 |
| Arvanitakis, S | 1 |
| Mangos, J | 1 |
| McSherry, NR | 1 |
| Rennert, O | 1 |
| Frias, J | 1 |
| Shukla, JB | 1 |
| Di Sant'Agnese, PA | 1 |
| McEvoy, FA | 1 |
| Hartley, CB | 1 |
2 reviews available for spermidine and Cystic Fibrosis
| Article | Year |
|---|---|
Polyamines spermidine and spermine as modulators of calcium-dependent immune processes.
Topics: Adenosine Diphosphate; Animals; Biological Transport; Calcium; Cystic Fibrosis; Enzyme Induction; ga | 1980 |
Clinical relevance of polyamines.
Topics: Animals; Cadaverine; Cystic Fibrosis; Diamines; Female; Growth Disorders; Humans; Kidney Failure, Ch | 1983 |
12 other studies available for spermidine and Cystic Fibrosis
| Article | Year |
|---|---|
Pseudomonas aeruginosa utilizes the host-derived polyamine spermidine to facilitate antimicrobial tolerance.
Topics: Animals; Anti-Infective Agents; Cystic Fibrosis; Mice; Microbial Sensitivity Tests; Polyamines; Pseu | 2022 |
Age-related abnormalities of circulating polyamines and diamine oxidase activity in cystic fibrosis heterozygotes and homozygotes.
Topics: Adolescent; Adult; Age Factors; Amine Oxidase (Copper-Containing); Child; Child, Preschool; Cystic F | 1980 |
Altered polyamine metabolism in cystic fibrosis.
Topics: Adult; Child; Child, Preschool; Cystic Fibrosis; Female; Heterozygote; Humans; Male; Polyamines; Put | 1979 |
Cystic fibrosis: decreased conjugation and excretion of [14C]spermidine.
Topics: Cystic Fibrosis; Humans; Spermidine | 1978 |
Spermine and spermidine, modulators of the cell surface enzyme adenylate cyclase.
Topics: Adenylyl Cyclase Inhibitors; Adult; Cell Membrane; Cells, Cultured; Child; Child, Preschool; Cystic | 1978 |
The effect of spermidine and spermine on proliferation in vitro of fibroblasts from normal and cystic fibrosis patients.
Topics: Cell Division; Cystic Fibrosis; Depression, Chemical; Fibroblasts; Humans; Spermidine; Spermine | 1976 |
Distribution of spermidine and spermine in blood from cystic fibrosis patients and control subjects.
Topics: Cell Fractionation; Cell Separation; Citrates; Cystic Fibrosis; Heparin; Humans; Male; Polyamines; S | 1976 |
Effect of polyamines and cystic fibrosis serum on glucose transport.
Topics: Adult; Animals; Child; Cystic Fibrosis; Epithelium; Female; Glucose; Heterozygote; Homozygote; Human | 1976 |
Polyamine metabolism in cystic fibrosis.
Topics: Animals; Cricetinae; Cystic Fibrosis; Electrolytes; Polyamines; Spermidine | 1976 |
Polyamine alterations in blood of male homozygotes and heterozygotes for cystic fibrosis.
Topics: Cystic Fibrosis; Female; Heterozygote; Homozygote; Humans; Male; Sex Factors; Spermidine; Spermine | 1975 |
Polyamines in cystic fibrosis.
Topics: Bile; Cystic Fibrosis; Duodenum; Humans; Intestinal Secretions; Polyamines; Saliva; Spermidine; Sper | 1975 |
Developments in cystic fibrosis research.
Topics: Biological Transport; Blood Glucose; Calcium; Cystic Fibrosis; Genes, Recessive; Heterozygote; Hexos | 1973 |