spermidine has been researched along with Colonic Neoplasms in 47 studies
Colonic Neoplasms: Tumors or cancer of the COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Exogenous spermine and ZmPAO treatment decreased cell viability in a spermine dose‑ and time‑dependent manner, particularly, the viability of the multidrug‑resistant (MDR) colon adenocarcinoma cells, LoVo DX, when compared with drug‑sensitive ones (LoVo WT)." | 7.91 | Maize polyamine oxidase in the presence of spermine/spermidine induces the apoptosis of LoVo human colon adenocarcinoma cells. ( Agostinelli, E; Angelini, R; Canettieri, G; Cona, A; Gaudio, E; Mancinelli, R; Miglietta, S; Ohkubo, S; Spandidos, DA, 2019) |
| "The association of N1-acetylspermidine with human colorectal adenocarcinomas has been evaluated in this study." | 7.67 | Selective elevation of the N1-acetylspermidine level in human colorectal adenocarcinomas. ( Hoshi, H; Kimura, H; Matsuzaki, S; Nakamura, T; Nakano, G; Shoda, H; Takenoshita, S, 1984) |
| "Here we determined whether Spd treatment reduces colitis and carcinogenesis." | 5.72 | Protective Role of Spermidine in Colitis and Colon Carcinogenesis. ( Allaman, MM; Asim, M; Barry, DP; Coburn, LA; Delgado, AG; Finley, JL; Gobert, AP; Latour, YL; Luis, PB; McNamara, KM; Piazuelo, MB; Schneider, C; Sierra, JC; Singh, K; Smith, TM; Washington, MK; Wilson, KT; Zhao, S, 2022) |
| " Exogenous spermine and ZmPAO treatment decreased cell viability in a spermine dose‑ and time‑dependent manner, particularly, the viability of the multidrug‑resistant (MDR) colon adenocarcinoma cells, LoVo DX, when compared with drug‑sensitive ones (LoVo WT)." | 3.91 | Maize polyamine oxidase in the presence of spermine/spermidine induces the apoptosis of LoVo human colon adenocarcinoma cells. ( Agostinelli, E; Angelini, R; Canettieri, G; Cona, A; Gaudio, E; Mancinelli, R; Miglietta, S; Ohkubo, S; Spandidos, DA, 2019) |
| "The association of N1-acetylspermidine with human colorectal adenocarcinomas has been evaluated in this study." | 3.67 | Selective elevation of the N1-acetylspermidine level in human colorectal adenocarcinomas. ( Hoshi, H; Kimura, H; Matsuzaki, S; Nakamura, T; Nakano, G; Shoda, H; Takenoshita, S, 1984) |
| "Here we determined whether Spd treatment reduces colitis and carcinogenesis." | 1.72 | Protective Role of Spermidine in Colitis and Colon Carcinogenesis. ( Allaman, MM; Asim, M; Barry, DP; Coburn, LA; Delgado, AG; Finley, JL; Gobert, AP; Latour, YL; Luis, PB; McNamara, KM; Piazuelo, MB; Schneider, C; Sierra, JC; Singh, K; Smith, TM; Washington, MK; Wilson, KT; Zhao, S, 2022) |
| "In total, 2502 colorectal cancer cases and 2538 age-(5-year interval) and sex-matched controls were recruited from July 2010 to April 2019." | 1.56 | Dietary Polyamines Intake and Risk of Colorectal Cancer: A Case-Control Study. ( Abulimiti, A; Chen, YM; Fang, YJ; Feng, XL; Huang, CY; Li, L; Liu, KY; Yang, X; Zhang, CX; Zhang, X, 2020) |
| "Thus, HGC-27 human gastric cancer cells and DLD-1 human colonic adenocarcinoma cells were evaluated." | 1.35 | Effects of Lactobacillus rhamnosus GG on proliferation and polyamine metabolism in HGC-27 human gastric and DLD-1 colonic cancer cell lines. ( Cavallini, A; Linsalata, M; Messa, C; Orlando, A; Russo, F, 2009) |
| "When human colon cancer cells were exposed to 7beta-OHsitosterol and to 7beta-OHcholesterol at concentrations inhibiting growth by the same degree, both compounds caused a reduction of polyamine biosynthetic enzyme activity, of the polyamine pools, and an increase of N1-acetylspermidine concentration indicating the enhancement of polyamine catabolism." | 1.33 | Perturbation of polyamine metabolism and its relation to cell death in human colon cancer cells treated by 7beta-hydroxycholesterol and 7beta-hydroxysitosterol. ( Aoudé-Werner, D; Geoffroy, P; Gossé, F; Marchioni, E; Miesch, M; Raul, F; Roussi, S; Zhang, X, 2006) |
| "In contrast to other cells of the body, colon cancer cells are exposed to high putrescine concentrations from the lumen." | 1.30 | S-adenosylmethionine decarboxylase activity and utilization of exogenous putrescine are enhanced in colon cancer cells stimulated to grow by EGF. ( Caspary, WF; Fares, FA; Lerner, A; Milovic, V; Stein, J; Turhanowa, L, 1998) |
| "once weekly for 20 wk to induce colon cancer." | 1.28 | Reduced growth rate of dimethylhydrazine-induced colon tumors in rats. ( Koike, T; Shibusawa, M; Tsunoda, A; Tsunoda, Y; Yasuda, N, 1992) |
| "A human colon cancer cell line Hce-8693 was heterotransplanted in nude mice." | 1.28 | [Inhibition by polyamine biosynthesis inhibitor DFMO of the growth of transplanted human colon cancer in nude mice]. ( Wang, M, 1991) |
| "Polyamine content of colorectal cancers was independent of tumour site, Dukes' stage, histological grade and the presence of palpable liver metastases at laparotomy." | 1.27 | Polyamines in colorectal cancer. ( Kingsnorth, AN; Lumsden, AB; Wallace, HM, 1984) |
| "The presence of GR in human colon cancers has been previously reported." | 1.27 | Polyamine levels and gastrin receptors in colon cancers. ( Barranco, SC; Saydjari, R; Singh, P; Thompson, JC; Townsend, CM; Upp, JR, 1988) |
| "RBC putrescine levels were significantly increased at a tumor weight of 12." | 1.27 | Relationship of erythrocyte polyamine levels and growth rate of transplantable tumors in rats. ( Grossie, VB; Martin, RG; Nishioka, K; Ota, DM, 1986) |
| "All 6 patients with localized malignant tumors had elevated urinary polyamine levels." | 1.25 | Urinary polyamine levels in human cancer. ( Kessler, GF; Lipton, A; Sheehan, LM, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (38.30) | 18.7374 |
| 1990's | 17 (36.17) | 18.2507 |
| 2000's | 7 (14.89) | 29.6817 |
| 2010's | 3 (6.38) | 24.3611 |
| 2020's | 2 (4.26) | 2.80 |
| Authors | Studies |
|---|---|
| Lakanen, JR | 1 |
| Coward, JK | 1 |
| Pegg, AE | 1 |
| Gobert, AP | 1 |
| Latour, YL | 1 |
| Asim, M | 1 |
| Barry, DP | 1 |
| Allaman, MM | 1 |
| Finley, JL | 1 |
| Smith, TM | 1 |
| McNamara, KM | 1 |
| Singh, K | 1 |
| Sierra, JC | 1 |
| Delgado, AG | 1 |
| Luis, PB | 1 |
| Schneider, C | 1 |
| Washington, MK | 1 |
| Piazuelo, MB | 1 |
| Zhao, S | 1 |
| Coburn, LA | 1 |
| Wilson, KT | 1 |
| Huang, CY | 1 |
| Fang, YJ | 1 |
| Abulimiti, A | 1 |
| Yang, X | 1 |
| Li, L | 1 |
| Liu, KY | 1 |
| Zhang, X | 2 |
| Feng, XL | 1 |
| Chen, YM | 1 |
| Zhang, CX | 1 |
| Ohkubo, S | 1 |
| Mancinelli, R | 1 |
| Miglietta, S | 1 |
| Cona, A | 1 |
| Angelini, R | 1 |
| Canettieri, G | 1 |
| Spandidos, DA | 1 |
| Gaudio, E | 1 |
| Agostinelli, E | 1 |
| Ralton, LD | 1 |
| Bestwick, CS | 1 |
| Milne, L | 1 |
| Duthie, S | 1 |
| Kong Thoo Lin, P | 1 |
| Orlando, A | 1 |
| Messa, C | 1 |
| Linsalata, M | 2 |
| Cavallini, A | 2 |
| Russo, F | 2 |
| Uemura, T | 1 |
| Stringer, DE | 1 |
| Blohm-Mangone, KA | 1 |
| Gerner, EW | 4 |
| Blachier, F | 1 |
| Davila, AM | 1 |
| Benamouzig, R | 1 |
| Tome, D | 1 |
| Babbar, N | 1 |
| Ignatenko, NA | 2 |
| Casero, RA | 4 |
| Kawakita, M | 1 |
| Hiramatsu, K | 1 |
| Sugimoto, M | 1 |
| Takahashi, K | 1 |
| Toi, M | 1 |
| Roussi, S | 1 |
| Gossé, F | 4 |
| Aoudé-Werner, D | 1 |
| Geoffroy, P | 1 |
| Miesch, M | 1 |
| Marchioni, E | 1 |
| Raul, F | 4 |
| Maldonado-Celisa, ME | 1 |
| Roussia, S | 1 |
| Foltzer-Jourdainne, C | 1 |
| Lobstein, A | 1 |
| Habold, C | 1 |
| Roessner, A | 1 |
| Schneider-Stock, R | 1 |
| Kingsnorth, AN | 1 |
| Lumsden, AB | 1 |
| Wallace, HM | 2 |
| Takenoshita, S | 1 |
| Matsuzaki, S | 1 |
| Nakano, G | 1 |
| Kimura, H | 1 |
| Hoshi, H | 1 |
| Shoda, H | 1 |
| Nakamura, T | 1 |
| Desser, H | 1 |
| Lutz, D | 1 |
| Krieger, O | 1 |
| Stierer, M | 1 |
| Higuchi, CM | 1 |
| Wang, W | 1 |
| Igarashi, K | 1 |
| Koga, K | 1 |
| He, Y | 1 |
| Shimogori, T | 1 |
| Ekimoto, H | 1 |
| Kashiwagi, K | 1 |
| Shirahata, A | 1 |
| McGarrity, TJ | 1 |
| Peiffer, LP | 1 |
| Berloco, P | 1 |
| Di Leo, A | 1 |
| Mackarel, AJ | 1 |
| Löser, C | 2 |
| Starp, F | 1 |
| Fölsch, UR | 2 |
| Duranton, B | 2 |
| Nsi-Emvo, E | 1 |
| Schleiffer, R | 2 |
| Galluser, M | 1 |
| Meyskens, FL | 1 |
| Emerson, S | 1 |
| Pelot, D | 1 |
| Durbin, T | 1 |
| Doyle, K | 1 |
| Lagerberg, W | 1 |
| Milovic, V | 1 |
| Turhanowa, L | 1 |
| Fares, FA | 1 |
| Lerner, A | 1 |
| Caspary, WF | 1 |
| Stein, J | 1 |
| Olaya, J | 1 |
| Neopikhanov, V | 1 |
| Uribe, A | 1 |
| Hasselmann, M | 1 |
| Lipton, A | 1 |
| Sheehan, LM | 1 |
| Kessler, GF | 1 |
| Nishioka, K | 5 |
| Romsdahl, MM | 3 |
| McMurtrey, MJ | 1 |
| Tsunoda, A | 2 |
| Shibusawa, M | 2 |
| Tsunoda, Y | 1 |
| Yasuda, N | 2 |
| Koike, T | 2 |
| Wang, M | 1 |
| Becciolini, A | 1 |
| Porciani, S | 1 |
| Lanini, A | 1 |
| Balzi, M | 1 |
| Cionini, L | 1 |
| Bandettini, L | 1 |
| Yoshizawa, H | 1 |
| Tsuno, K | 1 |
| Takeda, M | 1 |
| Paprotny, C | 1 |
| Creutzfeldt, W | 1 |
| Celano, P | 3 |
| Baylin, SB | 2 |
| Halline, AG | 3 |
| Dudeja, PK | 3 |
| Brasitus, TA | 3 |
| Berchtold, CM | 1 |
| Giardiello, FM | 2 |
| Lashner, BA | 1 |
| Ota, DM | 2 |
| Grossie, B | 1 |
| Dixon, D | 1 |
| Nelkin, BD | 1 |
| Upp, JR | 1 |
| Saydjari, R | 1 |
| Townsend, CM | 1 |
| Singh, P | 1 |
| Barranco, SC | 1 |
| Thompson, JC | 1 |
| Grossie, VB | 1 |
| Martin, RG | 1 |
| LaMuraglia, GM | 1 |
| Lacaine, F | 1 |
| Malt, RA | 1 |
| Thompson, JS | 1 |
| Edney, JA | 1 |
| Laughlin, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Immunomodulary Effects of Arginine Supplementation in Colitis and Colon Cancer[NCT01091558] | 204 participants (Actual) | Observational | 2009-09-30 | Completed | |||
| Urinary Excretion of Acetylamantadine by Cancer Patients[NCT02277938] | 120 participants (Anticipated) | Observational | 2013-08-31 | Recruiting | |||
| To Evaluate the Performance of a Urine Spermine Measuring Device in Predicting Prostate Biopsy Result[NCT04339920] | 0 participants (Actual) | Observational | 2021-09-01 | Withdrawn (stopped due to No funding) | |||
| To Identify Potential New Urine Marker Panel for Cancer Screening[NCT04689802] | 2,500 participants (Anticipated) | Observational | 2021-01-20 | Recruiting | |||
| TArgeting Type 1 Diabetes Using POLyamines (TADPOL): A Randomized, Double-Masked, Placebo-Controlled Phase 2 Study to Evaluate the Efficacy and Safety of Difluoromethylornithine (DFMO) to Preserve Insulin Production in Type 1 Diabetes[NCT05594563] | Phase 2 | 70 participants (Anticipated) | Interventional | 2023-03-14 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for spermidine and Colonic Neoplasms
| Article | Year |
|---|---|
Channelling of arginine in NO and polyamine pathways in colonocytes and consequences.
Topics: Agmatine; Animals; Arginine; Caco-2 Cells; Cell Proliferation; Colon; Colonic Neoplasms; Epithelial | 2011 |
[Clinical usefulness of urinary diacetylpolyamines as novel tumor markers].
Topics: Biomarkers, Tumor; Breast Neoplasms; Colonic Neoplasms; Enzyme-Linked Immunosorbent Assay; Female; H | 2004 |
1 trial available for spermidine and Colonic Neoplasms
| Article | Year |
|---|---|
Effect of alpha-difluoromethylornithine on rectal mucosal levels of polyamines in a randomized, double-blinded trial for colon cancer prevention.
Topics: Adult; Aged; Aged, 80 and over; Anticarcinogenic Agents; Audiometry; Colonic Neoplasms; Double-Blind | 1998 |
44 other studies available for spermidine and Colonic Neoplasms
| Article | Year |
|---|---|
alpha-Methyl polyamines: metabolically stable spermidine and spermine mimics capable of supporting growth in cells depleted of polyamines.
Topics: Animals; Cell Division; Cell Line, Transformed; Colonic Neoplasms; Eflornithine; Humans; Leukemia L1 | 1992 |
Protective Role of Spermidine in Colitis and Colon Carcinogenesis.
Topics: Adenomatous Polyposis Coli Protein; alpha-Defensins; Animals; Azoxymethane; Carcinogenesis; Colitis; | 2022 |
Dietary Polyamines Intake and Risk of Colorectal Cancer: A Case-Control Study.
Topics: Adult; Aged; Case-Control Studies; China; Colonic Neoplasms; Diet; Female; Humans; Male; Middle Aged | 2020 |
Maize polyamine oxidase in the presence of spermine/spermidine induces the apoptosis of LoVo human colon adenocarcinoma cells.
Topics: Adenocarcinoma; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colonic Neoplasms; Dose-Respons | 2019 |
Bisnaphthalimidopropyl spermidine induces apoptosis within colon carcinoma cells.
Topics: Acridine Orange; Antineoplastic Agents; Apoptosis; Caco-2 Cells; Chromatography, High Pressure Liqui | 2009 |
Effects of Lactobacillus rhamnosus GG on proliferation and polyamine metabolism in HGC-27 human gastric and DLD-1 colonic cancer cell lines.
Topics: Biogenic Polyamines; Biosynthetic Pathways; Cell Extracts; Cell Line, Tumor; Cell Proliferation; Cel | 2009 |
Polyamine transport is mediated by both endocytic and solute carrier transport mechanisms in the gastrointestinal tract.
Topics: Animals; Biological Transport; Catalysis; Caveolae; Caveolin 1; Cell Line, Tumor; Colonic Neoplasms; | 2010 |
Cyclooxygenase-independent induction of apoptosis by sulindac sulfone is mediated by polyamines in colon cancer.
Topics: Acetyltransferases; Apoptosis; Blotting, Northern; Blotting, Western; Caco-2 Cells; Cell Membrane; C | 2003 |
Perturbation of polyamine metabolism and its relation to cell death in human colon cancer cells treated by 7beta-hydroxycholesterol and 7beta-hydroxysitosterol.
Topics: Biogenic Polyamines; Caco-2 Cells; Cell Death; Cell Growth Processes; Colonic Neoplasms; Drug Synerg | 2006 |
Modulation by polyamines of apoptotic pathways triggered by procyanidins in human metastatic SW620 cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Colonic Neoplasms; Enzy | 2008 |
Polyamines in colorectal cancer.
Topics: Aged; Colonic Neoplasms; Female; Humans; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging; Polya | 1984 |
Selective elevation of the N1-acetylspermidine level in human colorectal adenocarcinomas.
Topics: Adenocarcinoma; Adenoma; Chromatography, High Pressure Liquid; Colonic Neoplasms; Humans; Rectal Neo | 1984 |
Rapid detection of polyamines in the sera of patients with colorectal carcinoma by liquid ion-exchange chromatography.
Topics: Aged; Cadaverine; Chromatography, Ion Exchange; Colonic Neoplasms; Female; Humans; Male; Middle Aged | 1980 |
Comodulation of cellular polyamines and proliferation: biomarker application to colorectal mucosa.
Topics: Biomarkers; Cell Division; Cell Line; Cells, Cultured; Chromatography, High Pressure Liquid; Colon; | 1995 |
Inhibition of the growth of various human and mouse tumor cells by 1,15-bis(ethylamino)-4,8,12-triazapentadecane.
Topics: Acetyltransferases; Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; Breast Neoplas | 1995 |
Selenium and difluoromethylornithine additively inhibit DMH-induced distal colon tumor formation in rats fed a fiber-free diet.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Colon; Colonic Neoplasms; Diet; Dietary Fiber; Dimethyl | 1993 |
Polyamines, diamine oxidase, and ornithine decarboxylase activity in colorectal cancer and in normal surrounding mucosa.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Amine Oxidase (Copper-Containing); Biomarkers, Tumor | 1993 |
Effect of 5-fluorouracil on polyamine excretion in human colonic cancer cells.
Topics: Colonic Neoplasms; Fluorouracil; Humans; Polyamines; Spermidine; Tumor Cells, Cultured | 1993 |
Dissimilar activation patterns of the carcinogen dimethylhydrazine (DMH) on intracellular polyamine metabolism in various organs.
Topics: 1,2-Dimethylhydrazine; Acetyltransferases; Adenosylmethionine Decarboxylase; Animals; Carcinogens; C | 1996 |
Suppression of preneoplastic changes in the intestine of rats fed low levels of polyamines.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Cell Movement; Colon; Colonic Neoplasms; Dimethylhydraz | 1997 |
Growth arrest- and polyamine-dependent expression of spermidine/spermine N1-acetyltransferase in human tumor cells.
Topics: Acetyltransferases; Blotting, Northern; Cell Division; Colonic Neoplasms; Dactinomycin; Eflornithine | 1996 |
S-adenosylmethionine decarboxylase activity and utilization of exogenous putrescine are enhanced in colon cancer cells stimulated to grow by EGF.
Topics: Adenosylmethionine Decarboxylase; Caco-2 Cells; Cell Division; Colonic Neoplasms; Dose-Response Rela | 1998 |
Lipopolysaccharide of Escherichia coli, polyamines, and acetic acid stimulate cell proliferation in intestinal epithelial cells.
Topics: Acetaldehyde; Acetic Acid; Adenocarcinoma; Ammonium Chloride; Animals; Cadaverine; Cell Division; Ce | 1999 |
Blood polyamine levels after oral ornithine load, a diagnostic marker of hyperproliferative premalignant and malignant stages in a model of colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Biomarkers, Tumor; Biotransformation; Body | 2000 |
Urinary polyamine levels in human cancer.
Topics: Adenocarcinoma; Adenoma; Bone Neoplasms; Breast Neoplasms; Bronchial Neoplasms; Carcinoma, Squamous | 1975 |
Serum polyamine alterations in surgical patients with colorectal carcinoma.
Topics: Colonic Diseases; Colonic Neoplasms; Female; Humans; Male; Middle Aged; Polyamines; Putrescine; Rect | 1977 |
Preliminary longitudinal studies of serum polyamines in patients with colorectal carcinoma.
Topics: Adenocarcinoma; Colonic Neoplasms; Humans; Intestinal Polyps; Longitudinal Studies; Middle Aged; Pro | 1977 |
Reduced growth rate of dimethylhydrazine-induced colon tumors in rats.
Topics: Animals; Body Weight; Cell Division; Colonic Neoplasms; Dimethylhydrazines; Eflornithine; Male; Mito | 1992 |
[Inhibition by polyamine biosynthesis inhibitor DFMO of the growth of transplanted human colon cancer in nude mice].
Topics: Animals; Bone Marrow; Cecal Neoplasms; Colonic Neoplasms; Eflornithine; Humans; Mice; Mice, Inbred B | 1991 |
Polyamine levels in healthy and tumor tissues of patients with colon adenocarcinoma.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Chromatography, High Pressure Liquid; Colon; Colonic | 1991 |
[Raised polyamines in erythrocytes of DMH administrated rats with colonic cancers and those relationship to tumor volume].
Topics: 1,2-Dimethylhydrazine; Animals; Colonic Neoplasms; Dimethylhydrazines; Erythrocytes; Male; Putrescin | 1991 |
Polyamines in colorectal cancer. Evaluation of polyamine concentrations in the colon tissue, serum, and urine of 50 patients with colorectal cancer.
Topics: Antigens, Tumor-Associated, Carbohydrate; Cadaverine; Carcinoembryonic Antigen; Colon; Colonic Neopl | 1990 |
Polyamines in colorectal cancer. Evaluation of polyamine concentrations in the colon tissue, serum, and urine of 50 patients with colorectal cancer.
Topics: Antigens, Tumor-Associated, Carbohydrate; Cadaverine; Carcinoembryonic Antigen; Colon; Colonic Neopl | 1990 |
Polyamines in colorectal cancer. Evaluation of polyamine concentrations in the colon tissue, serum, and urine of 50 patients with colorectal cancer.
Topics: Antigens, Tumor-Associated, Carbohydrate; Cadaverine; Carcinoembryonic Antigen; Colon; Colonic Neopl | 1990 |
Polyamines in colorectal cancer. Evaluation of polyamine concentrations in the colon tissue, serum, and urine of 50 patients with colorectal cancer.
Topics: Antigens, Tumor-Associated, Carbohydrate; Cadaverine; Carcinoembryonic Antigen; Colon; Colonic Neopl | 1990 |
Polyamines differentially modulate the transcription of growth-associated genes in human colon carcinoma cells.
Topics: Actins; Cell Division; Cell Line; Colonic Neoplasms; Eflornithine; Genes; Histones; Humans; Ornithin | 1989 |
1,2-Dimethylhydrazine-induced alterations in N1-acetylspermidine levels in rat distal colonic mucosa: effects of 2-difluoromethylornithine.
Topics: 1,2-Dimethylhydrazine; Acetyltransferases; Adenosylmethionine Decarboxylase; Animals; Chromatography | 1989 |
Modulation of growth gene expression by selective alteration of polyamines in human colon carcinoma cells.
Topics: Adenosine; Blotting, Northern; Cell Division; Cell Line; Colonic Neoplasms; Eflornithine; Gene Expre | 1989 |
Urinary excretion of N1-acetylspermidine and other acetylated and free polyamines in the 1,2-dimethylhydrazine model of experimental rat colon cancer.
Topics: 1,2-Dimethylhydrazine; Acetylation; Animals; Biogenic Polyamines; Biomarkers, Tumor; Colonic Neoplas | 1989 |
Premalignant alterations in rat colonic N1-acetylspermidine levels induced by 1,2-dimethylhydrazine: effects of a high corn oil dietary regimen.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Biogenic Polyamines; Colonic Neoplasms; Corn Oil; Di | 1989 |
Erythrocyte polyamine levels during intravenous feeding of patients with colorectal carcinoma.
Topics: Colonic Neoplasms; Erythrocytes; Humans; Parenteral Nutrition; Polyamines; Prealbumin; Putrescine; R | 1986 |
Effect of polyamine depletion on c-myc expression in human colon carcinoma cells.
Topics: Actins; Cell Cycle; Cell Division; Colonic Neoplasms; Dactinomycin; Eflornithine; Gene Expression Re | 1988 |
Polyamine levels and gastrin receptors in colon cancers.
Topics: Carcinoma; Colonic Neoplasms; Humans; Intestinal Mucosa; Neoplasm Staging; Polyamines; Putrescine; R | 1988 |
Relationship of erythrocyte polyamine levels and growth rate of transplantable tumors in rats.
Topics: Animals; Colonic Neoplasms; Fibrosarcoma; Hematocrit; Male; Neoplasms, Experimental; Polyamines; Put | 1986 |
High ornithine decarboxylase activity and polyamine levels in human colorectal neoplasia.
Topics: Adenocarcinoma; Cell Differentiation; Colonic Neoplasms; Humans; Intestinal Mucosa; Intestinal Polyp | 1986 |
Urinary polyamines in colorectal cancer.
Topics: Adult; Aged; Aged, 80 and over; Chromatography, High Pressure Liquid; Colitis, Ulcerative; Colonic N | 1986 |
Elevation of putrescine and spermidine in sera of patients with solid tumors.
Topics: Autoanalysis; Breast Neoplasms; Cadaverine; Carbon Radioisotopes; Carcinoma; Chromatography, Ion Exc | 1974 |