spermidine has been researched along with Cirrhosis in 5 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Spermidine supplementation is a potentially clinically meaningful approach to treating and curing liver fibrosis, preventing cirrhosis and HCC in patients." | 8.31 | Spermidine suppresses the activation of hepatic stellate cells to cure liver fibrosis through autophagy activator MAP1S. ( Ao, J; Jiang, X; Liang, M; Liang, X; Liu, L; Liu, Z; Shi, B; Wang, W; Xu, F; Xu, G; Ye, M; Yu, Z; Zhang, Y; Zhou, X, 2023) |
| " Here we report that arginine metabolism is the most altered in unilateral ureteral obstruction (UUO)-induced fibrosis of the kidneys in metabolomic analysis." | 8.31 | Spermidine from arginine metabolism activates Nrf2 and inhibits kidney fibrosis. ( Aihara, S; Imazu, N; Kitazono, T; Nakano, T; Torisu, K; Uchida, Y, 2023) |
| "HFD induced cardiac hypertrophy as demonstrated by higher volumes of the left ventricle, cardiomyocytes, interstitium, myofibrils and cardiomyocyte mitochondria." | 5.62 | Voluntary activity reverses spermidine-induced myocardial fibrosis and lipid accumulation in the obese male mouse. ( Bornemann, M; Mühlfeld, C; Pfeiffer, C; Schipke, J; Schneider, V, 2021) |
| "Spermidine supplementation is a potentially clinically meaningful approach to treating and curing liver fibrosis, preventing cirrhosis and HCC in patients." | 4.31 | Spermidine suppresses the activation of hepatic stellate cells to cure liver fibrosis through autophagy activator MAP1S. ( Ao, J; Jiang, X; Liang, M; Liang, X; Liu, L; Liu, Z; Shi, B; Wang, W; Xu, F; Xu, G; Ye, M; Yu, Z; Zhang, Y; Zhou, X, 2023) |
| " Here we report that arginine metabolism is the most altered in unilateral ureteral obstruction (UUO)-induced fibrosis of the kidneys in metabolomic analysis." | 4.31 | Spermidine from arginine metabolism activates Nrf2 and inhibits kidney fibrosis. ( Aihara, S; Imazu, N; Kitazono, T; Nakano, T; Torisu, K; Uchida, Y, 2023) |
| "HFD induced cardiac hypertrophy as demonstrated by higher volumes of the left ventricle, cardiomyocytes, interstitium, myofibrils and cardiomyocyte mitochondria." | 1.62 | Voluntary activity reverses spermidine-induced myocardial fibrosis and lipid accumulation in the obese male mouse. ( Bornemann, M; Mühlfeld, C; Pfeiffer, C; Schipke, J; Schneider, V, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 5 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ni, Y | 1 |
| Hu, Y | 1 |
| Lou, X | 1 |
| Rong, N | 1 |
| Liu, F | 1 |
| Yang, C | 1 |
| Zheng, A | 1 |
| Yang, S | 1 |
| Bao, J | 1 |
| Fu, Z | 1 |
| Shi, B | 1 |
| Wang, W | 1 |
| Ye, M | 1 |
| Liang, M | 1 |
| Yu, Z | 1 |
| Zhang, Y | 1 |
| Liu, Z | 1 |
| Liang, X | 1 |
| Ao, J | 1 |
| Xu, F | 1 |
| Xu, G | 1 |
| Jiang, X | 1 |
| Zhou, X | 1 |
| Liu, L | 1 |
| Wei, C | 1 |
| Xu, J | 1 |
| Liu, Y | 1 |
| Qadir, J | 1 |
| Zhang, S | 1 |
| Yuan, H | 1 |
| Aihara, S | 1 |
| Torisu, K | 1 |
| Uchida, Y | 1 |
| Imazu, N | 1 |
| Nakano, T | 1 |
| Kitazono, T | 1 |
| Mühlfeld, C | 1 |
| Pfeiffer, C | 1 |
| Schneider, V | 1 |
| Bornemann, M | 1 |
| Schipke, J | 1 |
5 other studies available for spermidine and Cirrhosis
| Article | Year |
|---|---|
Spermidine Ameliorates Nonalcoholic Steatohepatitis through Thyroid Hormone-Responsive Protein Signaling and the Gut Microbiota-Mediated Metabolism of Bile Acids.
Topics: Animals; Bile Acids and Salts; Fibrosis; Gastrointestinal Microbiome; Humans; Inflammation; Lipid Me | 2022 |
Spermidine suppresses the activation of hepatic stellate cells to cure liver fibrosis through autophagy activator MAP1S.
Topics: Animals; Autophagy; Carcinoma, Hepatocellular; Fatty Liver; Fibrosis; Hepatic Stellate Cells; Humans | 2023 |
Exogenous Spermidine Alleviates Diabetic Myocardial Fibrosis Via Suppressing Inflammation and Pyroptosis in db/db Mice
Topics: Animals; Collagen; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Fibrosis; Inflammatio | 2023 |
Spermidine from arginine metabolism activates Nrf2 and inhibits kidney fibrosis.
Topics: Animals; Arginine; Fibrosis; Humans; Kidney; Mice; Mice, Knockout; NF-E2-Related Factor 2; Renal Ins | 2023 |
Voluntary activity reverses spermidine-induced myocardial fibrosis and lipid accumulation in the obese male mouse.
Topics: Administration, Oral; Animals; Cardiomegaly; Diet, High-Fat; Fibrosis; Hypertrophy, Left Ventricular | 2021 |