Page last updated: 2024-10-20

spermidine and Cardiovascular Diseases

spermidine has been researched along with Cardiovascular Diseases in 7 studies

Cardiovascular Diseases: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.

Research Excerpts

ExcerptRelevanceReference
" Here we show that oral supplementation of the natural polyamine spermidine extends the lifespan of mice and exerts cardioprotective effects, reducing cardiac hypertrophy and preserving diastolic function in old mice."3.83Cardioprotection and lifespan extension by the natural polyamine spermidine. ( Abdellatif, M; Beckers, J; Büttner, S; Carmona-Gutierrez, D; Dammbrueck, C; de Angelis, MH; Dengjel, J; Eisenberg, T; Eller, K; Fuchs, H; Gailus-Durner, V; Gross, AS; Haemmerle, G; Harger, A; Herbst, V; Horsch, M; Hu, Z; Janik, D; Kiechl, S; Kirsch, A; Knittelfelder, O; Kroemer, G; Linke, WA; Madeo, F; Magnes, C; Mayr, M; Meinitzer, A; Moreth, K; Moustafa, T; Mühlfeld, C; Narath, S; Neff, F; Pechlaner, R; Pendl, T; Pieber, T; Pieske, B; Pietrocola, F; Primessnig, U; Rahn, A; Rathkolb, B; Rockenfeller, P; Rozman, J; Ruckenstuhl, C; Sadoshima, J; Schipke, J; Schmidt, A; Schrepfer, E; Schroeder, S; Scorrano, L; Sedej, S; Sigrist, SJ; Simonini, C; Stekovic, S; Tong, M; Trausinger, G; von Frieling-Salewsky, M; Willeit, J; Willeit, P; Zimmermann, A, 2016)
"Cardiovascular diseases are the most prominent maladies in aging societies."2.58Autophagy in Cardiovascular Aging. ( Abdellatif, M; Carmona-Gutierrez, D; Kroemer, G; Madeo, F; Sedej, S, 2018)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (71.43)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
Wu, H1
Wang, J1
Jiang, H1
Liu, X1
Sun, X1
Chen, Y1
Hu, C1
Wang, Z1
Han, T1
Sun, C1
Wei, W1
Jiang, W1
Abdellatif, M3
Ljubojevic-Holzer, S1
Madeo, F4
Sedej, S3
Eisenberg, T2
Pietrocola, F2
Kroemer, G3
Frati, G1
Vecchione, C1
Sciarretta, S1
Carmona-Gutierrez, D2
Schroeder, S1
Primessnig, U1
Stekovic, S1
Pendl, T1
Harger, A1
Schipke, J1
Zimmermann, A1
Schmidt, A1
Tong, M1
Ruckenstuhl, C1
Dammbrueck, C1
Gross, AS1
Herbst, V1
Magnes, C1
Trausinger, G1
Narath, S1
Meinitzer, A1
Hu, Z1
Kirsch, A1
Eller, K1
Büttner, S1
Knittelfelder, O1
Schrepfer, E1
Rockenfeller, P1
Simonini, C1
Rahn, A1
Horsch, M1
Moreth, K1
Beckers, J1
Fuchs, H1
Gailus-Durner, V1
Neff, F1
Janik, D1
Rathkolb, B1
Rozman, J1
de Angelis, MH1
Moustafa, T1
Haemmerle, G1
Mayr, M1
Willeit, P1
von Frieling-Salewsky, M1
Pieske, B1
Scorrano, L1
Pieber, T1
Pechlaner, R1
Willeit, J1
Sigrist, SJ1
Linke, WA1
Mühlfeld, C1
Sadoshima, J1
Dengjel, J1
Kiechl, S1
Soda, K1
Kano, Y1
Chiba, F1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Autophagy Characterization and Multi-level Molecular Profiling of Spermidine Supplementation: a Clinical Study[NCT04823806]80 participants (Anticipated)Interventional2020-12-01Active, not recruiting
Spermidine Anti-Hypertension Study[NCT04405388]Phase 346 participants (Anticipated)Interventional2020-02-25Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for spermidine and Cardiovascular Diseases

ArticleYear
Autophagy in cardiovascular health and disease.
    Progress in molecular biology and translational science, 2020, Volume: 172

    Topics: Aging; Animals; Autophagosomes; Autophagy; Autophagy-Related Proteins; Caloric Restriction; Cardiova

2020
Spermidine in health and disease.
    Science (New York, N.Y.), 2018, Jan-26, Volume: 359, Issue:6374

    Topics: Aging; Animals; Anti-Inflammatory Agents, Non-Steroidal; Autophagy; Biological Transport; Caloric Re

2018
Autophagy in Cardiovascular Aging.
    Circulation research, 2018, 09-14, Volume: 123, Issue:7

    Topics: Age Factors; Aging; Animals; Autophagy; Caloric Restriction; Cardiovascular Diseases; Cardiovascular

2018

Other Studies

4 other studies available for spermidine and Cardiovascular Diseases

ArticleYear
The association of dietary spermidine with all-cause mortality and CVD mortality: The U.S. National Health and Nutrition Examination Survey, 2003 to 2014.
    Frontiers in public health, 2022, Volume: 10

    Topics: Cardiovascular Diseases; Diet; Nutrition Surveys; Prospective Studies; Spermidine; Vegetables

2022
Novel Beneficial Cardiovascular Effects of Natural Activators of Autophagy.
    Circulation research, 2018, 09-28, Volume: 123, Issue:8

    Topics: Animals; Autophagy; Autophagy-Related Proteins; Cardiovascular Diseases; Cardiovascular System; Huma

2018
Cardioprotection and lifespan extension by the natural polyamine spermidine.
    Nature medicine, 2016, Volume: 22, Issue:12

    Topics: Adult; Aged; Aging; Animals; Autophagy; Autophagy-Related Protein 5; Blood Pressure; Cardiomegaly; C

2016
Food polyamine and cardiovascular disease--an epidemiological study.
    Global journal of health science, 2012, Sep-28, Volume: 4, Issue:6

    Topics: Cardiovascular Diseases; Diet; Fruit; Global Health; Gross Domestic Product; Humans; Linear Models;

2012