Page last updated: 2024-10-20

spermidine and Cardiac Failure

spermidine has been researched along with Cardiac Failure in 3 studies

Research Excerpts

ExcerptRelevanceReference
" Here we show that oral supplementation of the natural polyamine spermidine extends the lifespan of mice and exerts cardioprotective effects, reducing cardiac hypertrophy and preserving diastolic function in old mice."3.83Cardioprotection and lifespan extension by the natural polyamine spermidine. ( Abdellatif, M; Beckers, J; Büttner, S; Carmona-Gutierrez, D; Dammbrueck, C; de Angelis, MH; Dengjel, J; Eisenberg, T; Eller, K; Fuchs, H; Gailus-Durner, V; Gross, AS; Haemmerle, G; Harger, A; Herbst, V; Horsch, M; Hu, Z; Janik, D; Kiechl, S; Kirsch, A; Knittelfelder, O; Kroemer, G; Linke, WA; Madeo, F; Magnes, C; Mayr, M; Meinitzer, A; Moreth, K; Moustafa, T; Mühlfeld, C; Narath, S; Neff, F; Pechlaner, R; Pendl, T; Pieber, T; Pieske, B; Pietrocola, F; Primessnig, U; Rahn, A; Rathkolb, B; Rockenfeller, P; Rozman, J; Ruckenstuhl, C; Sadoshima, J; Schipke, J; Schmidt, A; Schrepfer, E; Schroeder, S; Scorrano, L; Sedej, S; Sigrist, SJ; Simonini, C; Stekovic, S; Tong, M; Trausinger, G; von Frieling-Salewsky, M; Willeit, J; Willeit, P; Zimmermann, A, 2016)
"Heart failure is an age-related disease, as the incidence increases with age."2.48Role of autophagy in aging. ( Otsu, K; Yamaguchi, O, 2012)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cheng, ML1
Wang, CH1
Shiao, MS1
Liu, MH1
Huang, YY1
Huang, CY1
Mao, CT1
Lin, JF1
Ho, HY1
Yang, NI1
Eisenberg, T1
Abdellatif, M1
Schroeder, S1
Primessnig, U1
Stekovic, S1
Pendl, T1
Harger, A1
Schipke, J1
Zimmermann, A1
Schmidt, A1
Tong, M1
Ruckenstuhl, C1
Dammbrueck, C1
Gross, AS1
Herbst, V1
Magnes, C1
Trausinger, G1
Narath, S1
Meinitzer, A1
Hu, Z1
Kirsch, A1
Eller, K1
Carmona-Gutierrez, D1
Büttner, S1
Pietrocola, F1
Knittelfelder, O1
Schrepfer, E1
Rockenfeller, P1
Simonini, C1
Rahn, A1
Horsch, M1
Moreth, K1
Beckers, J1
Fuchs, H1
Gailus-Durner, V1
Neff, F1
Janik, D1
Rathkolb, B1
Rozman, J1
de Angelis, MH1
Moustafa, T1
Haemmerle, G1
Mayr, M1
Willeit, P1
von Frieling-Salewsky, M1
Pieske, B1
Scorrano, L1
Pieber, T1
Pechlaner, R1
Willeit, J1
Sigrist, SJ1
Linke, WA1
Mühlfeld, C1
Sadoshima, J1
Dengjel, J1
Kiechl, S1
Kroemer, G1
Sedej, S1
Madeo, F1
Yamaguchi, O1
Otsu, K1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Spermidine Anti-Hypertension Study[NCT04405388]Phase 346 participants (Anticipated)Interventional2020-02-25Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for spermidine and Cardiac Failure

ArticleYear
Role of autophagy in aging.
    Journal of cardiovascular pharmacology, 2012, Volume: 60, Issue:3

    Topics: Aging; Animals; Autophagy; Caloric Restriction; Heart Failure; Humans; Sirolimus; Spermidine

2012

Other Studies

2 other studies available for spermidine and Cardiac Failure

ArticleYear
Metabolic disturbances identified in plasma are associated with outcomes in patients with heart failure: diagnostic and prognostic value of metabolomics.
    Journal of the American College of Cardiology, 2015, Apr-21, Volume: 65, Issue:15

    Topics: Amino Acids, Essential; Biomarkers; Carnitine; Case-Control Studies; Female; Heart Failure; Humans;

2015
Cardioprotection and lifespan extension by the natural polyamine spermidine.
    Nature medicine, 2016, Volume: 22, Issue:12

    Topics: Adult; Aged; Aging; Animals; Autophagy; Autophagy-Related Protein 5; Blood Pressure; Cardiomegaly; C

2016