Page last updated: 2024-10-20

spermidine and Cancer of Lung

spermidine has been researched along with Cancer of Lung in 23 studies

Research Excerpts

ExcerptRelevanceReference
" Hydroxycitrate, spermidine, and alpha-lipoic acid, CRMs that target different metabolic enzymes, administered by aerosol, strongly reduced implantation of intravenously injected B16 melanoma cells without overt signs of toxicity, such as weight loss and changes in lung structure."3.91Local Administration of Caloric Restriction Mimetics to Promote the Immune Control of Lung Metastases. ( Balsari, A; Bianchi, F; Le Noci, V; Sfondrini, L; Sommariva, M; Tagliabue, E; Triulzi, T, 2019)
"This study was conducted to examine the polyamine transporter (PAT) recognization and antitumor effects of anthracenymethyl homospermidine (ANTMHspd) and its apoptotic mechanism in B16 melanoma cells."3.75Polyamine transporter recognization and antitumor effects of anthracenymethyl homospermidine. ( Cheng, PF; Ma, HX; Wang, CJ; Wang, JH; Xie, SQ; Zhao, J, 2009)
"Most cases of breast cancer (BrCa) mortality are due to vascular metastasis."1.38HIF-1-dependent expression of angiopoietin-like 4 and L1CAM mediates vascular metastasis of hypoxic breast cancer cells to the lungs. ( Chaturvedi, P; Chen, J; Gilkes, DM; Korangath, P; Krishnamachary, B; Mitzner, WA; Raman, V; Schito, L; Semenza, GL; Sukumar, S; Wei, H; Winnard, PT; Wong, CC; Zhang, H; Zhen, L, 2012)
"All 6 patients with localized malignant tumors had elevated urinary polyamine levels."1.25Urinary polyamine levels in human cancer. ( Kessler, GF; Lipton, A; Sheehan, LM, 1975)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199013 (56.52)18.7374
1990's6 (26.09)18.2507
2000's2 (8.70)29.6817
2010's2 (8.70)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Le Noci, V1
Sommariva, M1
Bianchi, F1
Triulzi, T1
Tagliabue, E1
Balsari, A1
Sfondrini, L1
Xie, SQ1
Wang, JH1
Ma, HX1
Cheng, PF1
Zhao, J1
Wang, CJ1
Bandyopadhyay, K1
Banères, JL1
Martin, A1
Blonski, C1
Parello, J1
Gjerset, RA1
Zhang, H1
Wong, CC1
Wei, H1
Gilkes, DM1
Korangath, P1
Chaturvedi, P1
Schito, L1
Chen, J1
Krishnamachary, B1
Winnard, PT1
Raman, V1
Zhen, L1
Mitzner, WA1
Sukumar, S1
Semenza, GL1
Moulinoux, JP1
Quemener, V1
Larzul, JJ1
Le Calve, M1
Roch, AM1
Toujas, L1
Quash, G1
Woo, KB1
Waalkes, TP1
Abeloff, MD1
Lenhard, RE1
Gehrke, CW1
Kuo, KC1
Gutman, M1
Beltran, PJ1
Fan, D1
Delworth, MG1
Singh, RK1
Wilson, MR1
Fidler, IJ1
Igarashi, K1
Koga, K1
He, Y1
Shimogori, T1
Ekimoto, H1
Kashiwagi, K1
Shirahata, A1
Gerner, EW1
Kurtts, TA1
Fuller, DJ1
Casero, RA4
Felschow, DM1
Mi, Z1
Stanek, J1
Frei, J1
Porter, CW2
Lipton, A2
Sheehan, LM1
Kessler, GF1
Sheehan, L1
Mortel, R1
Harvey, HA1
Twentyman, PR1
Wright, KA1
Wallace, HM1
Abe, K1
Saito, T1
Kitamura, S1
Konaka, R1
Celano, P1
Ervin, SJ2
Bergeron, RJ1
Libby, PR1
Denstman, SC1
Chen, ZZ1
Fan, ZF1
Liu, CY1
Wang, JL1
Bassalyk, LS1
Tkacheva, GA1
Ausekar, BV1
Smirnova, KD1
Gershteĭn, ES1
Go, B1
Theiss, HW1
Smith, J1
Baylin, SB1
Luk, GD1
Sarhan, S2
Knodgen, B1
Gerhart, F1
Seiler, N2
Dezeure, F1
Hibasami, H1
Tsukada, T1
Nakashima, K1
Marton, LJ1
Russell, DH1
Levy, CC1

Reviews

1 review available for spermidine and Cancer of Lung

ArticleYear
[Cancer metastasis and polyamines].
    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1985, Volume: 30, Issue:5

    Topics: Adenosylmethionine Decarboxylase; Animals; Humans; Lung Neoplasms; Mammary Neoplasms, Experimental;

1985

Other Studies

22 other studies available for spermidine and Cancer of Lung

ArticleYear
Local Administration of Caloric Restriction Mimetics to Promote the Immune Control of Lung Metastases.
    Journal of immunology research, 2019, Volume: 2019

    Topics: Animals; Antigens, CD; Caloric Restriction; Citrates; Dendritic Cells; Integrin alpha Chains; Interl

2019
Polyamine transporter recognization and antitumor effects of anthracenymethyl homospermidine.
    Toxicology, 2009, Sep-19, Volume: 263, Issue:2-3

    Topics: Acetylcysteine; Animals; Anthracenes; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein;

2009
Spermidinyl-CoA-based HAT inhibitors block DNA repair and provide cancer-specific chemo- and radiosensitization.
    Cell cycle (Georgetown, Tex.), 2009, Sep-01, Volume: 8, Issue:17

    Topics: Acetylation; Antineoplastic Agents; Cell Line, Tumor; Coenzyme A; DNA Repair; Histone Acetyltransfer

2009
HIF-1-dependent expression of angiopoietin-like 4 and L1CAM mediates vascular metastasis of hypoxic breast cancer cells to the lungs.
    Oncogene, 2012, Apr-05, Volume: 31, Issue:14

    Topics: Angiopoietin-Like Protein 3; Angiopoietin-like Proteins; Angiopoietins; Animals; Breast Neoplasms; C

2012
Red blood cell polyamines in mice bearing the Lewis lung carcinoma (3LL) and in patients with bronchopulmonary cancers.
    International journal of cancer, 1984, Aug-15, Volume: 34, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Animals; Bronchial Neoplasms; Carcinoma, Small Cell; Carcinoma, Squamou

1984
Urinary polyamines for evaluating the course of disease for patients with small cell carcinoma of the lung.
    Cancer, 1983, Nov-01, Volume: 52, Issue:9

    Topics: Carcinoma, Small Cell; Creatinine; Humans; Lung Neoplasms; Neoplasm Metastasis; Polyamines; Putresci

1983
Treatment of nude mice with 4-amidinoindan -1- one2 '- amidinohydrazone, a new S-adenosylmethionine decarboxylase inhibitor, delays growth and inhibits metastasis of human melanoma cells.
    Melanoma research, 1995, Volume: 5, Issue:3

    Topics: Adenosylmethionine Decarboxylase; Amidines; Animals; Cell Division; Culture Media; Dose-Response Rel

1995
Inhibition of the growth of various human and mouse tumor cells by 1,15-bis(ethylamino)-4,8,12-triazapentadecane.
    Cancer research, 1995, Jun-15, Volume: 55, Issue:12

    Topics: Acetyltransferases; Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; Breast Neoplas

1995
Stress induction of the spermidine/spermine N1-acetyltransferase by a post-transcriptional mechanism in mammalian cells.
    The Biochemical journal, 1993, Sep-01, Volume: 294 ( Pt 2)

    Topics: Acetylation; Acetyltransferases; Animals; CHO Cells; Cricetinae; Ditiocarb; Eflornithine; Enzyme Ind

1993
Selective labelling of cell-surface polyamine-binding proteins on leukaemic and solid-tumour cell types using a new polyamine photoprobe.
    The Biochemical journal, 1997, Dec-15, Volume: 328 ( Pt 3)

    Topics: Animals; Binding, Competitive; Biological Transport; Carrier Proteins; Cell Membrane; Cross-Linking

1997
Urinary polyamine levels in human cancer.
    Cancer, 1975, Volume: 35, Issue:2

    Topics: Adenocarcinoma; Adenoma; Bone Neoplasms; Breast Neoplasms; Bronchial Neoplasms; Carcinoma, Squamous

1975
Urinary polyamine levels in patients with localized malignancy.
    Cancer, 1976, Volume: 38, Issue:3

    Topics: Adolescent; Adult; Female; Gastrointestinal Neoplasms; Genital Neoplasms, Female; Humans; Lung Neopl

1976
Effects of cyclosporin A and a non-immunosuppressive analogue, O-acetyl cyclosporin A, upon the growth of parent and multidrug resistant human lung cancer cells in vitro.
    British journal of cancer, 1992, Volume: 65, Issue:3

    Topics: Adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Division; Cell Line; Cel

1992
Elevated spermidine level in pleural fluid of patients with lung cancer.
    Clinica chimica acta; international journal of clinical chemistry, 1990, Apr-30, Volume: 188, Issue:2

    Topics: Body Fluids; Chromatography, High Pressure Liquid; Humans; Lung Neoplasms; Pleura; Pleural Effusion;

1990
Differential induction of spermidine/spermine N1-acetyltransferase in human lung cancer cells by the bis(ethyl)polyamine analogues.
    Cancer research, 1989, Jul-15, Volume: 49, Issue:14

    Topics: Acetyltransferases; Antineoplastic Agents; Carcinoma, Small Cell; Cell Line; Enzyme Induction; Human

1989
Comparison of the effects of treatment with the polyamine analogue N1,N8 bis(ethyl)spermidine (BESpd) or difluoromethylornithine (DFMO) on the Topoisomerase II mediated formation of 4'-(9-acridinylamino) methanesulfon-m-anisidide (m-AMSA) induced cleavabl
    Biochemical and biophysical research communications, 1987, Nov-30, Volume: 149, Issue:1

    Topics: Amsacrine; Chemical Precipitation; DNA Topoisomerases, Type II; DNA, Neoplasm; Eflornithine; Humans;

1987
[Studies on polyamine radioimmunoassay. III. Spermidine radioimmunoassay].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 1985, Volume: 7, Issue:2

    Topics: Humans; Lung Neoplasms; Radioimmunoassay; Spermidine

1985
[Biochemical methods and their place in prognosis and evaluation of the effectiveness of treatment of small cell lung cancer].
    Voprosy onkologii, 1985, Volume: 31, Issue:10

    Topics: Adrenocorticotropic Hormone; Adult; Aged; Calcitonin; Carcinoembryonic Antigen; Carcinoma, Small Cel

1985
Cytotoxic response of the relatively difluoromethylornithine-resistant human lung tumor cell line NCI H157 to the polyamine analogue N1,N8-bis(ethyl)spermidine.
    Cancer research, 1987, Aug-01, Volume: 47, Issue:15

    Topics: Carcinoma, Non-Small-Cell Lung; Cell Division; Cell Line; Cell Survival; Dose-Response Relationship,

1987
Chain-fluorinated polyamines as tumor markers--I. In vivo transformation of 2,2-difluoroputrescine into 6,6-difluorospermidine and 6,6-difluorospermine.
    The International journal of biochemistry, 1987, Volume: 19, Issue:9

    Topics: Animals; Biomarkers, Tumor; Biotransformation; Cattle; Cell Division; Eflornithine; Female; Liver Ne

1987
Chain-fluorinated polyamines as tumor markers--IV. Comparison of 2-fluoroputrescine and 2,2-difluoroputrescine as substrates of spermidine synthase in vitro and in vivo.
    The International journal of biochemistry, 1988, Volume: 20, Issue:11

    Topics: Animals; Binding Sites; Biomarkers, Tumor; Dose-Response Relationship, Drug; In Vitro Techniques; Li

1988
Measurement of putrescine, spermidine, and spermine in physiological fluids by use of an amino acid analyzer.
    Clinical chemistry, 1973, Volume: 19, Issue:8

    Topics: Autoanalysis; Carbon Isotopes; Carcinoma, Squamous Cell; Chromatography, Ion Exchange; Humans; Lung

1973