spermidine has been researched along with Brain Ischemia in 7 studies
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A significant increase of the spermidine level in the peripheral blood could be observed in all patients with focal cerebral ischemia as compared with control subjects (P:<0." | 9.09 | Spermidine: A predictor for neurological outcome and infarct size in focal cerebral ischemia? ( Bruckmann, J; Daffertshofer, M; Els, T; Ernestus, RI; Hennerici, M; Mönting, JS; Röhn, G, 2001) |
| " The effects of addition of putrescine on IR will be evaluated in terms of inflammation and oxidant-antioxidant balance in liver." | 8.31 | Effects of putrescine on oxidative stress, spermidine/spermine-N(1)-acetyltransferase, inflammation and energy levels in liver and serum in rats with brain ischemia-reperfusion. ( Baltaci, AK; Cetin, N; Dasdelen, D; Menevse, E; Mogulkoc, R, 2023) |
| "A significant increase of the spermidine level in the peripheral blood could be observed in all patients with focal cerebral ischemia as compared with control subjects (P:<0." | 5.09 | Spermidine: A predictor for neurological outcome and infarct size in focal cerebral ischemia? ( Bruckmann, J; Daffertshofer, M; Els, T; Ernestus, RI; Hennerici, M; Mönting, JS; Röhn, G, 2001) |
| " The effects of addition of putrescine on IR will be evaluated in terms of inflammation and oxidant-antioxidant balance in liver." | 4.31 | Effects of putrescine on oxidative stress, spermidine/spermine-N(1)-acetyltransferase, inflammation and energy levels in liver and serum in rats with brain ischemia-reperfusion. ( Baltaci, AK; Cetin, N; Dasdelen, D; Menevse, E; Mogulkoc, R, 2023) |
| "Putrescine, spermidine, and spermine levels were measured in the cortex, caudoputamen, and hippocampus of rats during 30 min of severe forebrain ischemia (induced by occlusion of both carotid and vertebral arteries) and subsequent recirculation." | 3.67 | Polyamine changes in reversible cerebral ischemia. ( Djuricic, B; Hossmann, KA; Linn, F; Meese, C; Paschen, W; Schmidt-Kastner, R, 1987) |
| " These data indicate that the polyamine spermine is toxic to neurons in vitro and that toxicity is prevented by the NMDA-associated channel antagonist dizocilpine." | 1.29 | Polyamine neurotoxicity is antagonized by dizocilpine in cultured chick cortical neurons. ( Fahey, JM; Miller, LG; Pritchard, GA, 1993) |
| "Putrescine efflux was significantly increased in 2/5 animals with MCA occlusion but the increase in release was similar to the spontaneous fluctuations observed in control animals." | 1.29 | Release of spermidine from the rat cortex following permanent middle cerebral artery occlusion. ( Carboni, S; Carter, C; Fage, D; Poignet, H; Scatton, B; Voltz, C, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Dasdelen, D | 1 |
| Cetin, N | 1 |
| Menevse, E | 1 |
| Baltaci, AK | 1 |
| Mogulkoc, R | 1 |
| Diler, AS | 1 |
| Ziylan, YZ | 1 |
| Uzum, G | 1 |
| Lefauconnier, JM | 1 |
| Seylaz, J | 1 |
| Pinard, E | 1 |
| Fahey, JM | 1 |
| Pritchard, GA | 1 |
| Miller, LG | 1 |
| Carter, C | 1 |
| Poignet, H | 1 |
| Carboni, S | 1 |
| Fage, D | 1 |
| Voltz, C | 1 |
| Scatton, B | 1 |
| Els, T | 1 |
| Bruckmann, J | 1 |
| Röhn, G | 1 |
| Daffertshofer, M | 1 |
| Mönting, JS | 1 |
| Ernestus, RI | 1 |
| Hennerici, M | 1 |
| Sauer, D | 1 |
| Martin, P | 1 |
| Allegrini, PR | 1 |
| Bernasconi, R | 1 |
| Amacker, H | 1 |
| Fagg, GE | 1 |
| Paschen, W | 1 |
| Schmidt-Kastner, R | 1 |
| Djuricic, B | 1 |
| Meese, C | 1 |
| Linn, F | 1 |
| Hossmann, KA | 1 |
1 trial available for spermidine and Brain Ischemia
| Article | Year |
|---|---|
Spermidine: A predictor for neurological outcome and infarct size in focal cerebral ischemia?
Topics: Aged; Brain; Brain Ischemia; Chromatography, High Pressure Liquid; Erythrocytes; Female; Follow-Up S | 2001 |
6 other studies available for spermidine and Brain Ischemia
| Article | Year |
|---|---|
Effects of putrescine on oxidative stress, spermidine/spermine-N(1)-acetyltransferase, inflammation and energy levels in liver and serum in rats with brain ischemia-reperfusion.
Topics: Acetyltransferases; Animals; Brain Ischemia; Inflammation; Liver; Male; Oxidative Stress; Putrescine | 2023 |
Passage of spermidine across the blood-brain barrier in short recirculation periods following global cerebral ischemia: effects of mild hyperthermia.
Topics: Aminoisobutyric Acids; Animals; Blood-Brain Barrier; Brain; Brain Ischemia; Hypothermia, Induced; Ma | 2002 |
Polyamine neurotoxicity is antagonized by dizocilpine in cultured chick cortical neurons.
Topics: Animals; Brain Ischemia; Cell Survival; Cells, Cultured; Cerebral Cortex; Chick Embryo; Dizocilpine | 1993 |
Release of spermidine from the rat cortex following permanent middle cerebral artery occlusion.
Topics: Animals; Brain Ischemia; Cerebral Arteries; Cerebral Cortex; Chromatography, High Pressure Liquid; E | 1995 |
Differing effects of alpha-difluoromethylornithine and CGP 40116 on polyamine levels and infarct volume in a rat model of focal cerebral ischaemia.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Brain Ischemia; Cerebral Infarction; Eflornithine; Magn | 1992 |
Polyamine changes in reversible cerebral ischemia.
Topics: Animals; Brain Ischemia; Cerebral Cortex; Hippocampus; Polyamines; Putamen; Putrescine; Rats; Spermi | 1987 |