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spermidine and B16 Melanoma

spermidine has been researched along with B16 Melanoma in 12 studies

Research Excerpts

ExcerptRelevanceReference
"The uptake of intracellular putrescine and spermidine was examined in B16 melanoma cells."7.68Evidence for the existence of distinct transporters for the polyamines putrescine and spermidine in B16 melanoma cells. ( Ilett, KF; Martin, RL; Minchin, RF; Raso, A, 1991)
" Hydroxycitrate, spermidine, and alpha-lipoic acid, CRMs that target different metabolic enzymes, administered by aerosol, strongly reduced implantation of intravenously injected B16 melanoma cells without overt signs of toxicity, such as weight loss and changes in lung structure."3.91Local Administration of Caloric Restriction Mimetics to Promote the Immune Control of Lung Metastases. ( Balsari, A; Bianchi, F; Le Noci, V; Sfondrini, L; Sommariva, M; Tagliabue, E; Triulzi, T, 2019)
"This study was conducted to examine the polyamine transporter (PAT) recognization and antitumor effects of anthracenymethyl homospermidine (ANTMHspd) and its apoptotic mechanism in B16 melanoma cells."3.75Polyamine transporter recognization and antitumor effects of anthracenymethyl homospermidine. ( Cheng, PF; Ma, HX; Wang, CJ; Wang, JH; Xie, SQ; Zhao, J, 2009)
"The uptake of intracellular putrescine and spermidine was examined in B16 melanoma cells."3.68Evidence for the existence of distinct transporters for the polyamines putrescine and spermidine in B16 melanoma cells. ( Ilett, KF; Martin, RL; Minchin, RF; Raso, A, 1991)
"We have examined the effect of difluoromethylornithine on the ability of B16 melanoma cells to take up putrescine and the 4,4'-dipyridyl herbicide paraquat."3.67Paraquat is not accumulated in B16 tumor cells by the polyamine transport system. ( Ilett, KF; Martin, RL; Minchin, RF, 1989)
"DFMO inhibited the proliferation of B16 melanoma cells in culture but the inhibitory effect was much less than that on BPAE cells."1.28Tumor angiogenesis and polyamines: alpha-difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase, inhibits B16 melanoma-induced angiogenesis in ovo and the proliferation of vascular endothelial cells in vitro. ( Enomoto, M; Kinoshita, A; Nishida, Y; Pan, HO; Suzuki, F; Takigawa, M, 1990)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's6 (50.00)18.2507
2000's3 (25.00)29.6817
2010's2 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhuo, JC1
Cai, J1
Soloway, AH1
Barth, RF1
Adams, DM1
Ji, W1
Tjarks, W1
Le Noci, V1
Sommariva, M1
Bianchi, F1
Triulzi, T1
Tagliabue, E1
Balsari, A1
Sfondrini, L1
Xie, SQ1
Wang, JH1
Ma, HX1
Cheng, PF1
Zhao, J1
Wang, CJ1
Yamamichi, S1
Nishitani, M1
Nishimura, N1
Matsushita, Y1
Hasumi, K1
Baldini, PM1
Lentini, A2
Mattioli, P1
Provenzano, B2
De Vito, P1
Vismara, D1
Beninati, S3
Caraglia, M1
Shevchenko, A1
Abbruzzese, A2
Cardinali, M1
Stark, PA1
Thrall, BD1
Meadows, GG1
Abdel-Monem, MM1
Regenass, U1
Caravatti, G1
Mett, H1
Stanek, J1
Schneider, P1
Müller, M1
Matter, A1
Vertino, P1
Porter, CW1
Takigawa, M1
Enomoto, M1
Nishida, Y1
Pan, HO1
Kinoshita, A1
Suzuki, F1
Minchin, RF2
Raso, A1
Martin, RL2
Ilett, KF2

Other Studies

12 other studies available for spermidine and B16 Melanoma

ArticleYear
Synthesis and biological evaluation of boron-containing polyamines as potential agents for neutron capture therapy of brain tumors.
    Journal of medicinal chemistry, 1999, Apr-08, Volume: 42, Issue:7

    Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cattle; DNA; Glioma; Melan

1999
Local Administration of Caloric Restriction Mimetics to Promote the Immune Control of Lung Metastases.
    Journal of immunology research, 2019, Volume: 2019

    Topics: Animals; Antigens, CD; Caloric Restriction; Citrates; Dendritic Cells; Integrin alpha Chains; Interl

2019
Polyamine transporter recognization and antitumor effects of anthracenymethyl homospermidine.
    Toxicology, 2009, Sep-19, Volume: 263, Issue:2-3

    Topics: Acetylcysteine; Animals; Anthracenes; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein;

2009
Polyamine-promoted autoactivation of plasma hyaluronan-binding protein.
    Journal of thrombosis and haemostasis : JTH, 2010, Volume: 8, Issue:3

    Topics: Allosteric Regulation; Amino Acid Sequence; Animals; Binding Sites; Blood Coagulation; Carmine; Cell

2010
Decrease of polyamine levels and enhancement of transglutaminase activity in selective reduction of B16-F10 melanoma cell proliferation induced by atrial natriuretic peptide.
    Melanoma research, 2006, Volume: 16, Issue:6

    Topics: Animals; Aorta; Atrial Natriuretic Factor; Cell Line, Tumor; Cell Proliferation; Epidermal Growth Fa

2006
Impairment of the metastatic activity of melanoma cells by transglutaminase-catalyzed incorporation of polyamines into laminin and Matrigel.
    Amino acids, 2008, Volume: 34, Issue:2

    Topics: Animals; Cell Adhesion; Cell Migration Assays; Collagen; Drug Combinations; Laminin; Matrix Metallop

2008
Differences in the post-translational modification of proteins by polyamines between weakly and highly metastatic B16 melanoma cells.
    International journal of cancer, 1993, Mar-12, Volume: 53, Issue:5

    Topics: Animals; Melanins; Melanoma, Experimental; Mice; Neoplasm Metastasis; Neoplasm Proteins; Putrescine;

1993
Synthesis and evaluation of novel spermidine derivatives as targeted cancer chemotherapeutic agents.
    Journal of medicinal chemistry, 1992, Nov-13, Volume: 35, Issue:23

    Topics: Antineoplastic Agents; Cell Division; Chromatography, High Pressure Liquid; Melanoma, Experimental;

1992
New S-adenosylmethionine decarboxylase inhibitors with potent antitumor activity.
    Cancer research, 1992, Sep-01, Volume: 52, Issue:17

    Topics: Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; Cell Division; DNA, Mitochondrial;

1992
Tumor angiogenesis and polyamines: alpha-difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase, inhibits B16 melanoma-induced angiogenesis in ovo and the proliferation of vascular endothelial cells in vitro.
    Cancer research, 1990, Jul-01, Volume: 50, Issue:13

    Topics: Animals; Cattle; Cell Division; Chick Embryo; DNA, Neoplasm; Eflornithine; Endothelium, Vascular; Me

1990
Evidence for the existence of distinct transporters for the polyamines putrescine and spermidine in B16 melanoma cells.
    European journal of biochemistry, 1991, Sep-01, Volume: 200, Issue:2

    Topics: Affinity Labels; Biological Transport; Carrier Proteins; Eflornithine; Kinetics; Melanoma, Experimen

1991
Paraquat is not accumulated in B16 tumor cells by the polyamine transport system.
    Life sciences, 1989, Volume: 45, Issue:1

    Topics: Biological Transport; Dose-Response Relationship, Drug; Eflornithine; Kinetics; Melanoma, Experiment

1989