spermidine has been researched along with Arthritis, Rheumatoid in 4 studies
Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chu, SH | 1 |
| Cui, J | 1 |
| Sparks, JA | 1 |
| Lu, B | 1 |
| Tedeschi, SK | 1 |
| Speyer, CB | 1 |
| Moss, L | 1 |
| Feser, ML | 1 |
| Kelmenson, LB | 1 |
| Mewshaw, EA | 1 |
| Edison, JD | 1 |
| Deane, KD | 1 |
| Clish, C | 1 |
| Lasky-Su, J | 1 |
| Karlson, EW | 1 |
| Costenbader, KH | 1 |
| Shaw, AM | 1 |
| Qasem, A | 1 |
| Naser, SA | 1 |
| Furumitsu, Y | 1 |
| Yukioka, K | 1 |
| Yukioka, M | 1 |
| Ochi, T | 1 |
| Morishima, Y | 1 |
| Matsui-Yuasa, I | 1 |
| Otani, S | 1 |
| Inaba, M | 1 |
| Nishizawa, Y | 1 |
| Morii, H | 1 |
| Flescher, E | 1 |
| Bowlin, TL | 1 |
| Ballester, A | 1 |
| Houk, R | 1 |
| Talal, N | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| TArgeting Type 1 Diabetes Using POLyamines (TADPOL): A Randomized, Double-Masked, Placebo-Controlled Phase 2 Study to Evaluate the Efficacy and Safety of Difluoromethylornithine (DFMO) to Preserve Insulin Production in Type 1 Diabetes[NCT05594563] | Phase 2 | 70 participants (Anticipated) | Interventional | 2023-03-14 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for spermidine and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Circulating plasma metabolites and risk of rheumatoid arthritis in the Nurses' Health Study.
Topics: Adult; Age Factors; Arthritis, Rheumatoid; Body Mass Index; Butyric Acid; Caprylates; Carnitine; Cas | 2020 |
Modulation of
Topics: Arthritis, Rheumatoid; CRISPR-Cas Systems; Crohn Disease; Gene Expression Regulation, Leukemic; Gene | 2021 |
Interleukin-1beta induces elevation of spermidine/spermine N1-acetyltransferase activity and an increase in the amount of putrescine in synovial adherent cells from patients with rheumatoid arthritis.
Topics: Acetyltransferases; Arthritis, Rheumatoid; Cell Division; Cells, Cultured; Collagenases; Dinoproston | 2000 |
Increased polyamines may downregulate interleukin 2 production in rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Biogenic Polyamines; Cell Separation; Cells, Cultured; Female; H | 1989 |