spermidine has been researched along with Arthritis, Degenerative in 4 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Spermidine has been known to inhibit the production of pro-inflammatory cytokines." | 5.56 | Spermidine activates RIP1 deubiquitination to inhibit TNF-α-induced NF-κB/p65 signaling pathway in osteoarthritis. ( Chen, Z; Ding, Y; Fang, GB; Fu, Y; Li, CC; Li, SX; Lin, CX; Lin, SP; Luo, WQ; Qiu, JX; Saw, PE; Song, B; Wei-Ping, L, 2020) |
| "Spermidine (SPD) is a natural polyamine that shows beneficial effects on osteoarthritis (OA)." | 4.31 | BRG1 mediates protective ability of spermidine to ameliorate osteoarthritic cartilage by Nrf2/KEAP1 and STAT3 signaling pathway. ( Chen, H; Lai, P; Ma, J; Mao, X; Yan, B, 2023) |
| "Osteoarthritis is a common multifactorial chronic disease that occurs in articular cartilage, subchondral bone, and periarticular tissue." | 1.62 | Analysis of Serum Metabolomics in Rats with Osteoarthritis by Mass Spectrometry. ( Chen, L; Gao, M; Guan, F; He, K; Li, J; Liu, M; Lv, Y; Shi, T; Zhang, H; Zhang, M; Zhao, J; Zhao, Y, 2021) |
| "Spermidine has been known to inhibit the production of pro-inflammatory cytokines." | 1.56 | Spermidine activates RIP1 deubiquitination to inhibit TNF-α-induced NF-κB/p65 signaling pathway in osteoarthritis. ( Chen, Z; Ding, Y; Fang, GB; Fu, Y; Li, CC; Li, SX; Lin, CX; Lin, SP; Luo, WQ; Qiu, JX; Saw, PE; Song, B; Wei-Ping, L, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 3 (75.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhao, J | 1 |
| Liu, M | 1 |
| Shi, T | 1 |
| Gao, M | 1 |
| Lv, Y | 1 |
| Zhao, Y | 1 |
| Li, J | 1 |
| Zhang, M | 1 |
| Zhang, H | 1 |
| Guan, F | 1 |
| He, K | 1 |
| Chen, L | 1 |
| Mao, X | 1 |
| Yan, B | 1 |
| Chen, H | 1 |
| Lai, P | 1 |
| Ma, J | 1 |
| Chen, Z | 1 |
| Lin, CX | 1 |
| Song, B | 1 |
| Li, CC | 1 |
| Qiu, JX | 1 |
| Li, SX | 1 |
| Lin, SP | 1 |
| Luo, WQ | 1 |
| Fu, Y | 1 |
| Fang, GB | 1 |
| Wei-Ping, L | 1 |
| Saw, PE | 1 |
| Ding, Y | 1 |
| Sacitharan, PK | 1 |
| Lwin, S | 1 |
| Gharios, GB | 1 |
| Edwards, JR | 1 |
4 other studies available for spermidine and Arthritis, Degenerative
| Article | Year |
|---|---|
Analysis of Serum Metabolomics in Rats with Osteoarthritis by Mass Spectrometry.
Topics: Animals; Biomarkers; Cartilage, Articular; Chromatography, Liquid; Collagenases; Disease Models, Ani | 2021 |
BRG1 mediates protective ability of spermidine to ameliorate osteoarthritic cartilage by Nrf2/KEAP1 and STAT3 signaling pathway.
Topics: Animals; Antioxidants; Cartilage, Articular; Chondrocytes; Humans; Inflammation; Kelch-Like ECH-Asso | 2023 |
Spermidine activates RIP1 deubiquitination to inhibit TNF-α-induced NF-κB/p65 signaling pathway in osteoarthritis.
Topics: Animals; Anterior Cruciate Ligament Injuries; Cartilage, Articular; Cell Line; Deubiquitinating Enzy | 2020 |
Spermidine restores dysregulated autophagy and polyamine synthesis in aged and osteoarthritic chondrocytes via EP300.
Topics: Animals; Autophagy; Biomarkers; Cellular Senescence; Chondrocytes; Chondrogenesis; E1A-Associated p3 | 2018 |