Page last updated: 2024-10-20

spermidine and Adenoma, Prostatic

spermidine has been researched along with Adenoma, Prostatic in 12 studies

Research Excerpts

ExcerptRelevanceReference
" Tissue concentrations of polyamines can be detected by cation exchange analysis and putrescine, spermine and spermidine were assayed in specimens of benign hyperplasia of prostate and renal adenocarcinoma and in normal control tissues."3.66Determination of putrescine, spermine and spermidine in human tissues of prostate and kidney. ( Dunzendorfer, U; Russell, DH, 1980)
"PCa, benign prostatic hyperplasia (BPH) patients and healthy controls (HC) showing PSA>4."1.43Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers. ( Chan, CF; Chan, WL; Chiu, KF; Ng, CF; Tsoi, TH; Wong, KL; Wong, WT, 2016)
"Only 29% of the patients with breast carcinoma had elevated levels of spermidine compared to normal female subjects."1.26Plasma spermidine concentrations in patients with tumours of the breast or prostate or testis. ( Blamey, RW; Chaisiri, P; Griffiths, K; Harper, ME; Peeling, WB, 1980)
"All 6 patients with localized malignant tumors had elevated urinary polyamine levels."1.25Urinary polyamine levels in human cancer. ( Kessler, GF; Lipton, A; Sheehan, LM, 1975)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19909 (75.00)18.7374
1990's2 (16.67)18.2507
2000's0 (0.00)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tsoi, TH1
Chan, CF1
Chan, WL1
Chiu, KF1
Wong, WT1
Ng, CF1
Wong, KL1
Chaisiri, P2
Harper, ME2
Blamey, RW1
Peeling, WB2
Griffiths, K2
Dunzendorfer, U5
Russell, DH3
Slade, J1
Lipton, A1
Sheehan, LM1
Kessler, GF1
Cipolla, B2
Guille, F2
Quemener, V2
Lévêque, JM1
Moulinoux, JP2
Lobel, B2
Havouis, R1
Martin, LA1
Knöner, M1
Sakai, S1
Ito, Y1
Koide, T1
Tei, K1
Hara, A1
Sawada, H1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Artificial Intelligence (AI)-Assisted Risk-based Prostate Cancer Detection: A Synergy of Novel Biomarkers, Advanced Imaging, and Robotic-assisted Diagnosis[NCT05443412]510 participants (Anticipated)Observational2022-08-01Not yet recruiting
To Evaluate the Performance of a Urine Spermine Measuring Device in Predicting Prostate Biopsy Result[NCT04339920]0 participants (Actual)Observational2021-09-01Withdrawn (stopped due to No funding)
To Investigate the Diagnostic Accuracy of Exosomal microRNA in Predicting the Aggressiveness of Prostate Cancer in Chinese Patients[NCT03911999]180 participants (Actual)Observational2018-05-03Completed
To Identify Potential New Urine Marker Panel for Cancer Screening[NCT04689802]2,500 participants (Anticipated)Observational2021-01-20Recruiting
To Investigate the Role of Gut Microbiome in Androgen Deprivation Therapy Related Metabolic Changes in Prostate Cancer Patients[NCT04687709]50 participants (Anticipated)Observational2021-01-14Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for spermidine and Adenoma, Prostatic

ArticleYear
Prostate cancer. Hormonal relationships, receptors, and tumour markers.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1981, Volume: 78

    Topics: Acid Phosphatase; Aged; Androgens; Humans; Male; Polyamines; Prostatic Hyperplasia; Prostatic Neopla

1981

Other Studies

11 other studies available for spermidine and Adenoma, Prostatic

ArticleYear
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromato

2016
Plasma spermidine concentrations in patients with tumours of the breast or prostate or testis.
    Clinica chimica acta; international journal of clinical chemistry, 1980, Jul-01, Volume: 104, Issue:3

    Topics: Adult; Aged; Breast Neoplasms; Female; Humans; Male; Menopause; Middle Aged; Pregnancy; Prostatic Hy

1980
Determination of putrescine, spermine and spermidine in human tissues of prostate and kidney.
    Arzneimittel-Forschung, 1980, Volume: 30, Issue:10

    Topics: Adenocarcinoma; Adult; Humans; Kidney; Kidney Neoplasms; Male; Polyamines; Prostate; Prostatic Hyper

1980
[Therapy of prostate carcinoma with polyamine synthesis inhibitors. I. Physiological and pathophysiological principles].
    Urologia internationalis, 1982, Volume: 37, Issue:5

    Topics: Antineoplastic Agents; Humans; Male; Polyamines; Prostatic Hyperplasia; Prostatic Neoplasms; Putresc

1982
Urinary polyamine levels in human cancer.
    Cancer, 1975, Volume: 35, Issue:2

    Topics: Adenocarcinoma; Adenoma; Bone Neoplasms; Breast Neoplasms; Bronchial Neoplasms; Carcinoma, Squamous

1975
Altered polyamine profiles in prostatic hyperplasia and in kidney tumors.
    Cancer research, 1978, Volume: 38, Issue:8

    Topics: Adult; Aged; Female; Humans; Kidney; Kidney Neoplasms; Male; Middle Aged; Polyamines; Prostate; Pros

1978
Altered polyamines and peptide hormones (FSH, TSH, prolactin, C-peptide) in prostatic hyperplasia and kidney tumors.
    Cellular and molecular biology, including cyto-enzymology, 1979, Volume: 24, Issue:4

    Topics: C-Peptide; Follicle Stimulating Hormone; Humans; Kidney; Kidney Neoplasms; Male; Peptides; Polyamine

1979
[The diagnostic value of erythrocyte polyamines (EPA) in prostatic adenocarcinoma (PA): apropos of 100 patients].
    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie, 1992, Volume: 2, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Erythrocytes; Humans; Male; Middl

1992
Erythrocyte polyamine levels in human prostatic carcinoma.
    The Journal of urology, 1990, Volume: 144, Issue:5

    Topics: Adenocarcinoma; Aged; Chromatography, High Pressure Liquid; Erythrocytes; Humans; Male; Prostatic Hy

1990
[Therapy with inhibitors of polyamine biosynthesis in refractory prostatic carcinoma. An experimental and clinical study].
    Onkologie, 1985, Volume: 8, Issue:4

    Topics: Adenocarcinoma; Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; Carboxy-Lyases; Ca

1985
[Detection of urinary polyamine by a new enzymatic differential assay. (III). Studies on urinary polyamines in patients with malignant genitourinary diseases].
    Hinyokika kiyo. Acta urologica Japonica, 1986, Volume: 32, Issue:3

    Topics: Diamines; Humans; Kidney Neoplasms; Male; Polyamines; Prostatic Hyperplasia; Prostatic Neoplasms; Sp

1986