spermidine has been researched along with Adenocarcinoma in 29 studies
Adenocarcinoma: A malignant epithelial tumor with a glandular organization.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Exogenous spermine and ZmPAO treatment decreased cell viability in a spermine dose‑ and time‑dependent manner, particularly, the viability of the multidrug‑resistant (MDR) colon adenocarcinoma cells, LoVo DX, when compared with drug‑sensitive ones (LoVo WT)." | 7.91 | Maize polyamine oxidase in the presence of spermine/spermidine induces the apoptosis of LoVo human colon adenocarcinoma cells. ( Agostinelli, E; Angelini, R; Canettieri, G; Cona, A; Gaudio, E; Mancinelli, R; Miglietta, S; Ohkubo, S; Spandidos, DA, 2019) |
| "Urinary N1-acetylspermidine (N1SPD) and N8-acetylspermidine (N8SPD) were measured in 24-hr urine specimens from 42 patients with colon adenocarcinoma and 29 healthy controls to assess their use as markers for colon cancer screening." | 7.69 | Urinary N1-acetylspermidine and N8-acetylspermidine excretion in normal humans and in patients with colorectal cancer. ( Brasitus, TA; Halline, AG; Hankewych, M; Jacoby, R; McCormick, D; O'Brien, BL, 1995) |
| "The association of N1-acetylspermidine with human colorectal adenocarcinomas has been evaluated in this study." | 7.67 | Selective elevation of the N1-acetylspermidine level in human colorectal adenocarcinomas. ( Hoshi, H; Kimura, H; Matsuzaki, S; Nakamura, T; Nakano, G; Shoda, H; Takenoshita, S, 1984) |
| "Because alpha-difluoromethylornithine (DFMO) reduces the incidence of experimental colon cancers, inhibits the growth of human lung cancer cells and human leukemia cells in culture, and in combination with methylglyoxal (bis)guanylhydrazone induces remission in children with leukemia, its effectiveness against a human colon adenocarcinoma cell line (Colo 205) was tested alone and in combination with 5-fluorouracil (5-FU)." | 7.66 | Effects of alpha-difluoromethylornithine and 5-fluorouracil on the proliferation of a human colon adenocarcinoma cell line. ( Diekema, KA; Kingsnorth, AN; Malt, RA; McCann, PP; Russell, WE, 1983) |
| "Histamine was detected in 3 of the 6 cases of thyroid carcinomas, and in case of adenomatous goiter." | 5.26 | Elevated levels of polyamines and histamine in adenocarcinomas of the thyroid. ( Hamana, K; Itoh, K; Matsuzaki, S; Suzuki, M, 1978) |
| " Exogenous spermine and ZmPAO treatment decreased cell viability in a spermine dose‑ and time‑dependent manner, particularly, the viability of the multidrug‑resistant (MDR) colon adenocarcinoma cells, LoVo DX, when compared with drug‑sensitive ones (LoVo WT)." | 3.91 | Maize polyamine oxidase in the presence of spermine/spermidine induces the apoptosis of LoVo human colon adenocarcinoma cells. ( Agostinelli, E; Angelini, R; Canettieri, G; Cona, A; Gaudio, E; Mancinelli, R; Miglietta, S; Ohkubo, S; Spandidos, DA, 2019) |
| "Urinary N1-acetylspermidine (N1SPD) and N8-acetylspermidine (N8SPD) were measured in 24-hr urine specimens from 42 patients with colon adenocarcinoma and 29 healthy controls to assess their use as markers for colon cancer screening." | 3.69 | Urinary N1-acetylspermidine and N8-acetylspermidine excretion in normal humans and in patients with colorectal cancer. ( Brasitus, TA; Halline, AG; Hankewych, M; Jacoby, R; McCormick, D; O'Brien, BL, 1995) |
| "We evaluated polyamine (putrescine, spermidine, and spermine) levels, estrogen receptor concentrations, and their relationship in neoplastic tissue and surrounding mucosa from 30 patients with gastric adenocarcinoma." | 3.69 | Estrogen receptors and polyamine levels in human gastric carcinoma. ( Cavallini, A; Di Leo, A; Linsalata, M; Messa, C; Russo, F, 1994) |
| "We assayed the estrogen receptors and polyamine levels (putrescine, spermidine and spermine) in the neoplastic and "normal" surrounding tissue of patients with colorectal cancer." | 3.68 | Polyamines and estrogen-receptor concentrations in human colorectal carcinomas. ( Cavallini, A; Di Leo, A; Guerra, V; Lacatena, M; Lantone, G; Linsalata, M; Messa, C; Notarnicola, M; Russo, F, 1992) |
| "The association of N1-acetylspermidine with human colorectal adenocarcinomas has been evaluated in this study." | 3.67 | Selective elevation of the N1-acetylspermidine level in human colorectal adenocarcinomas. ( Hoshi, H; Kimura, H; Matsuzaki, S; Nakamura, T; Nakano, G; Shoda, H; Takenoshita, S, 1984) |
| " Tissue concentrations of polyamines can be detected by cation exchange analysis and putrescine, spermine and spermidine were assayed in specimens of benign hyperplasia of prostate and renal adenocarcinoma and in normal control tissues." | 3.66 | Determination of putrescine, spermine and spermidine in human tissues of prostate and kidney. ( Dunzendorfer, U; Russell, DH, 1980) |
| "Because alpha-difluoromethylornithine (DFMO) reduces the incidence of experimental colon cancers, inhibits the growth of human lung cancer cells and human leukemia cells in culture, and in combination with methylglyoxal (bis)guanylhydrazone induces remission in children with leukemia, its effectiveness against a human colon adenocarcinoma cell line (Colo 205) was tested alone and in combination with 5-fluorouracil (5-FU)." | 3.66 | Effects of alpha-difluoromethylornithine and 5-fluorouracil on the proliferation of a human colon adenocarcinoma cell line. ( Diekema, KA; Kingsnorth, AN; Malt, RA; McCann, PP; Russell, WE, 1983) |
| "Histamine was detected in 3 of the 6 cases of thyroid carcinomas, and in case of adenomatous goiter." | 1.26 | Elevated levels of polyamines and histamine in adenocarcinomas of the thyroid. ( Hamana, K; Itoh, K; Matsuzaki, S; Suzuki, M, 1978) |
| "All 6 patients with localized malignant tumors had elevated urinary polyamine levels." | 1.25 | Urinary polyamine levels in human cancer. ( Kessler, GF; Lipton, A; Sheehan, LM, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (41.38) | 18.7374 |
| 1990's | 10 (34.48) | 18.2507 |
| 2000's | 3 (10.34) | 29.6817 |
| 2010's | 3 (10.34) | 24.3611 |
| 2020's | 1 (3.45) | 2.80 |
| Authors | Studies |
|---|---|
| Sierra, JC | 1 |
| Piazuelo, MB | 1 |
| Luis, PB | 1 |
| Barry, DP | 1 |
| Allaman, MM | 1 |
| Asim, M | 1 |
| Sebrell, TA | 1 |
| Finley, JL | 1 |
| Rose, KL | 1 |
| Hill, S | 1 |
| Holshouser, SL | 1 |
| Casero, RA | 1 |
| Cleveland, JL | 1 |
| Woster, PM | 1 |
| Schey, KL | 1 |
| Bimczok, D | 1 |
| Schneider, C | 1 |
| Gobert, AP | 1 |
| Wilson, KT | 1 |
| Ohkubo, S | 1 |
| Mancinelli, R | 1 |
| Miglietta, S | 1 |
| Cona, A | 1 |
| Angelini, R | 1 |
| Canettieri, G | 1 |
| Spandidos, DA | 1 |
| Gaudio, E | 1 |
| Agostinelli, E | 1 |
| Morada, M | 1 |
| Pendyala, L | 1 |
| Wu, G | 1 |
| Merali, S | 1 |
| Yarlett, N | 1 |
| Jung, H | 1 |
| Park, KM | 1 |
| Yang, JA | 1 |
| Oh, EJ | 1 |
| Lee, DW | 1 |
| Park, K | 1 |
| Ryu, SH | 1 |
| Hahn, SK | 1 |
| Kim, K | 1 |
| Weiss, TS | 1 |
| Bernhardt, G | 1 |
| Buschauer, A | 1 |
| Thasler, WE | 1 |
| Dolgner, D | 1 |
| Zirngibl, H | 1 |
| Jauch, KW | 1 |
| Moulinoux, JP | 3 |
| Quemener, V | 3 |
| Larzul, JJ | 1 |
| Le Calve, M | 1 |
| Roch, AM | 1 |
| Toujas, L | 1 |
| Quash, G | 1 |
| Dunzendorfer, U | 2 |
| Russell, DH | 1 |
| Kingsnorth, AN | 2 |
| Russell, WE | 1 |
| McCann, PP | 1 |
| Diekema, KA | 1 |
| Malt, RA | 2 |
| Takenoshita, S | 1 |
| Matsuzaki, S | 2 |
| Nakano, G | 1 |
| Kimura, H | 1 |
| Hoshi, H | 1 |
| Shoda, H | 1 |
| Nakamura, T | 1 |
| O'Brien, BL | 1 |
| Hankewych, M | 1 |
| McCormick, D | 1 |
| Jacoby, R | 1 |
| Brasitus, TA | 2 |
| Halline, AG | 2 |
| Linsalata, M | 3 |
| Messa, C | 2 |
| Russo, F | 3 |
| Cavallini, A | 3 |
| Di Leo, A | 3 |
| Berloco, P | 1 |
| Gray, MR | 1 |
| Wallace, HM | 2 |
| Goulding, H | 1 |
| Hoffman, J | 1 |
| Kenyon, WE | 1 |
| Olaya, J | 1 |
| Neopikhanov, V | 1 |
| Uribe, A | 1 |
| Schleiffer, R | 1 |
| Duranton, B | 1 |
| Gossé, F | 1 |
| Hasselmann, M | 1 |
| Raul, F | 1 |
| Cohen, RJ | 1 |
| Fujiwara, K | 1 |
| Holland, JW | 1 |
| McNeal, JE | 1 |
| Lipton, A | 1 |
| Sheehan, LM | 1 |
| Kessler, GF | 1 |
| Suzuki, M | 1 |
| Hamana, K | 1 |
| Itoh, K | 1 |
| Matsuda, M | 1 |
| Osafune, M | 1 |
| Kotake, T | 1 |
| Sonoda, T | 1 |
| Sobue, K | 1 |
| Nakajima, T | 1 |
| Nishioka, K | 1 |
| Romsdahl, MM | 1 |
| Cipolla, B | 2 |
| Guille, F | 2 |
| Lévêque, JM | 1 |
| Lobel, B | 2 |
| Twentyman, PR | 1 |
| Wright, KA | 1 |
| Notarnicola, M | 1 |
| Guerra, V | 1 |
| Lantone, G | 1 |
| Lacatena, M | 1 |
| Havouis, R | 1 |
| Martin, LA | 1 |
| Becciolini, A | 1 |
| Porciani, S | 1 |
| Lanini, A | 1 |
| Balzi, M | 1 |
| Cionini, L | 1 |
| Bandettini, L | 1 |
| Knöner, M | 1 |
| Hawrylewicz, EJ | 1 |
| Moshovitis, CK | 1 |
| Reger, C | 1 |
| Madell, J | 1 |
| Dudeja, PK | 1 |
| LaMuraglia, GM | 1 |
| Lacaine, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Urinary Excretion of Acetylamantadine by Cancer Patients[NCT02277938] | 120 participants (Anticipated) | Observational | 2013-08-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
29 other studies available for spermidine and Adenocarcinoma
| Article | Year |
|---|---|
Spermine oxidase mediates Helicobacter pylori-induced gastric inflammation, DNA damage, and carcinogenic signaling.
Topics: Adenocarcinoma; Animals; beta Catenin; Cell Transformation, Neoplastic; DNA Damage; Gastritis; Helic | 2020 |
Maize polyamine oxidase in the presence of spermine/spermidine induces the apoptosis of LoVo human colon adenocarcinoma cells.
Topics: Adenocarcinoma; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colonic Neoplasms; Dose-Respons | 2019 |
Cryptosporidium parvum induces an endoplasmic stress response in the intestinal adenocarcinoma HCT-8 cell line.
Topics: Acetyltransferases; Adenocarcinoma; Apoptosis; Calreticulin; Cell Line, Tumor; Cryptosporidiosis; Cr | 2013 |
Theranostic systems assembled in situ on demand by host-guest chemistry.
Topics: Adenocarcinoma; Animals; Breast Neoplasms; Bridged-Ring Compounds; Cell Line, Tumor; Female; Fluores | 2011 |
Polyamine levels of human colorectal adenocarcinomas are correlated with tumor stage and grade.
Topics: Acetyltransferases; Adenocarcinoma; Aged; Biomarkers, Tumor; Chromatography, Liquid; Colorectal Neop | 2002 |
Red blood cell polyamines in mice bearing the Lewis lung carcinoma (3LL) and in patients with bronchopulmonary cancers.
Topics: Adenocarcinoma; Adult; Aged; Animals; Bronchial Neoplasms; Carcinoma, Small Cell; Carcinoma, Squamou | 1984 |
Determination of putrescine, spermine and spermidine in human tissues of prostate and kidney.
Topics: Adenocarcinoma; Adult; Humans; Kidney; Kidney Neoplasms; Male; Polyamines; Prostate; Prostatic Hyper | 1980 |
Effects of alpha-difluoromethylornithine and 5-fluorouracil on the proliferation of a human colon adenocarcinoma cell line.
Topics: Adenocarcinoma; Antineoplastic Agents; Cell Cycle; Cell Line; Cell Survival; Eflornithine; Fluoroura | 1983 |
Selective elevation of the N1-acetylspermidine level in human colorectal adenocarcinomas.
Topics: Adenocarcinoma; Adenoma; Chromatography, High Pressure Liquid; Colonic Neoplasms; Humans; Rectal Neo | 1984 |
Urinary N1-acetylspermidine and N8-acetylspermidine excretion in normal humans and in patients with colorectal cancer.
Topics: Adenocarcinoma; Adult; Chromatography, High Pressure Liquid; Circadian Rhythm; Colorectal Neoplasms; | 1995 |
Estrogen receptors and polyamine levels in human gastric carcinoma.
Topics: Adenocarcinoma; Biogenic Polyamines; Female; Gastric Mucosa; Humans; Male; Middle Aged; Putrescine; | 1994 |
Polyamines, diamine oxidase, and ornithine decarboxylase activity in colorectal cancer and in normal surrounding mucosa.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Amine Oxidase (Copper-Containing); Biomarkers, Tumor | 1993 |
Mucosal polyamine metabolism in the columnar lined oesophagus.
Topics: Adenocarcinoma; Barrett Esophagus; Biomarkers; Chromatography, High Pressure Liquid; Esophageal Neop | 1993 |
Lipopolysaccharide of Escherichia coli, polyamines, and acetic acid stimulate cell proliferation in intestinal epithelial cells.
Topics: Acetaldehyde; Acetic Acid; Adenocarcinoma; Ammonium Chloride; Animals; Cadaverine; Cell Division; Ce | 1999 |
Blood polyamine levels after oral ornithine load, a diagnostic marker of hyperproliferative premalignant and malignant stages in a model of colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Biomarkers, Tumor; Biotransformation; Body | 2000 |
Polyamines in prostatic epithelial cells and adenocarcinoma; the effects of androgen blockade.
Topics: Adenocarcinoma; Androgen Antagonists; Eosinophils; Epithelial Cells; Humans; Immunohistochemistry; M | 2001 |
Urinary polyamine levels in human cancer.
Topics: Adenocarcinoma; Adenoma; Bone Neoplasms; Breast Neoplasms; Bronchial Neoplasms; Carcinoma, Squamous | 1975 |
Elevated levels of polyamines and histamine in adenocarcinomas of the thyroid.
Topics: Adenocarcinoma; Adenoma; Adult; DNA; Female; Graves Disease; Histamine; Humans; Middle Aged; Polyami | 1978 |
Concentrations of polyamines in renal cell carcinoma.
Topics: Adenocarcinoma; Adult; Aged; DNA, Neoplasm; Female; Humans; Kidney; Kidney Neoplasms; Male; Middle A | 1978 |
Preliminary longitudinal studies of serum polyamines in patients with colorectal carcinoma.
Topics: Adenocarcinoma; Colonic Neoplasms; Humans; Intestinal Polyps; Longitudinal Studies; Middle Aged; Pro | 1977 |
[The diagnostic value of erythrocyte polyamines (EPA) in prostatic adenocarcinoma (PA): apropos of 100 patients].
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Erythrocytes; Humans; Male; Middl | 1992 |
Effects of cyclosporin A and a non-immunosuppressive analogue, O-acetyl cyclosporin A, upon the growth of parent and multidrug resistant human lung cancer cells in vitro.
Topics: Adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Division; Cell Line; Cel | 1992 |
Polyamines and estrogen-receptor concentrations in human colorectal carcinomas.
Topics: Adenocarcinoma; Adult; Aged; Carcinoembryonic Antigen; Colorectal Neoplasms; Female; Humans; Intesti | 1992 |
Erythrocyte polyamine levels in human prostatic carcinoma.
Topics: Adenocarcinoma; Aged; Chromatography, High Pressure Liquid; Erythrocytes; Humans; Male; Prostatic Hy | 1990 |
Polyamine levels in healthy and tumor tissues of patients with colon adenocarcinoma.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Chromatography, High Pressure Liquid; Colon; Colonic | 1991 |
[Therapy with inhibitors of polyamine biosynthesis in refractory prostatic carcinoma. An experimental and clinical study].
Topics: Adenocarcinoma; Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; Carboxy-Lyases; Ca | 1985 |
Dietary protein enhanced mammary ornithine decarboxylase activity and tumorigenesis in rats.
Topics: Adenocarcinoma; Animals; Dietary Proteins; Epithelium; Female; Liver; Mammary Glands, Animal; Mammar | 1989 |
Premalignant alterations in rat colonic N1-acetylspermidine levels induced by 1,2-dimethylhydrazine: effects of a high corn oil dietary regimen.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Biogenic Polyamines; Colonic Neoplasms; Corn Oil; Di | 1989 |
High ornithine decarboxylase activity and polyamine levels in human colorectal neoplasia.
Topics: Adenocarcinoma; Cell Differentiation; Colonic Neoplasms; Humans; Intestinal Mucosa; Intestinal Polyp | 1986 |