spermidine has been researched along with Acute Confusional Senile Dementia in 14 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Supplementation with spermidine may support healthy aging, but elevated spermidine tissue levels were shown to be an indicator of Alzheimer's disease (AD)." | 8.31 | Association of spermidine plasma levels with brain aging in a population-based study. ( Bahls, M; Bülow, R; Flöel, A; Frenzel, S; Friedrich, N; Grabe, HJ; Habes, M; Nauck, M; Schwarz, C; Van der Auwera, S; Völzke, H; Wittfeld, K; Wortha, SM; Zylla, S, 2023) |
| " This work investigates three hallmarks of the disease (autophagy, neuroinflammation, and senescence) and systematically analyzes if there is a beneficial effect from three substances derived from food sources, the so called "nutraceuticals" epigallocatechin gallate, fisetin, and spermidine, on these hallmarks." | 5.05 | Nutraceutical Approaches of Autophagy and Neuroinflammation in Alzheimer's Disease: A Systematic Review. ( Gruendler, R; Haslberger, AG; Hippe, B; Peterlin, B; Sendula Jengic, V, 2020) |
| "Supplementation with spermidine may support healthy aging, but elevated spermidine tissue levels were shown to be an indicator of Alzheimer's disease (AD)." | 4.31 | Association of spermidine plasma levels with brain aging in a population-based study. ( Bahls, M; Bülow, R; Flöel, A; Frenzel, S; Friedrich, N; Grabe, HJ; Habes, M; Nauck, M; Schwarz, C; Van der Auwera, S; Völzke, H; Wittfeld, K; Wortha, SM; Zylla, S, 2023) |
| "Abnormal tau build-up is a hallmark of Alzheimer's disease (AD) and more than 20 other serious neurodegenerative diseases." | 1.91 | Spermidine Rescues Bioenergetic and Mitophagy Deficits Induced by Disease-Associated Tau Protein. ( Eckert, A; Fairley, LH; Grimm, A; Lejri, I, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (21.43) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 8 (57.14) | 2.80 |
| Authors | Studies |
|---|---|
| Sternberg, Z | 1 |
| Podolsky, R | 1 |
| Nir, A | 1 |
| Yu, J | 1 |
| Nir, R | 1 |
| Halvorsen, SW | 1 |
| Quinn, JF | 1 |
| Kaye, J | 1 |
| Kolb, C | 1 |
| Freitag, K | 1 |
| Sterczyk, N | 1 |
| Wendlinger, S | 1 |
| Obermayer, B | 1 |
| Schulz, J | 1 |
| Farztdinov, V | 1 |
| Mülleder, M | 1 |
| Ralser, M | 1 |
| Houtman, J | 1 |
| Fleck, L | 1 |
| Braeuning, C | 1 |
| Sansevrino, R | 1 |
| Hoffmann, C | 1 |
| Milovanovic, D | 1 |
| Sigrist, SJ | 1 |
| Conrad, T | 1 |
| Beule, D | 1 |
| Heppner, FL | 1 |
| Jendrach, M | 1 |
| Wortha, SM | 1 |
| Frenzel, S | 1 |
| Bahls, M | 1 |
| Habes, M | 1 |
| Wittfeld, K | 1 |
| Van der Auwera, S | 1 |
| Bülow, R | 1 |
| Zylla, S | 1 |
| Friedrich, N | 1 |
| Nauck, M | 1 |
| Völzke, H | 1 |
| Grabe, HJ | 1 |
| Schwarz, C | 1 |
| Flöel, A | 1 |
| Fairley, LH | 1 |
| Lejri, I | 1 |
| Grimm, A | 1 |
| Eckert, A | 1 |
| Pekar, T | 2 |
| Wendzel, A | 2 |
| Flak, W | 2 |
| Kremer, A | 2 |
| Pauschenwein-Frantsich, S | 2 |
| Gschaider, A | 2 |
| Wantke, F | 2 |
| Jarisch, R | 2 |
| Bruckner, K | 1 |
| Oppliger, M | 1 |
| Willesberger, J | 1 |
| Ungersbäck, P | 1 |
| Gruendler, R | 1 |
| Hippe, B | 1 |
| Sendula Jengic, V | 1 |
| Peterlin, B | 1 |
| Haslberger, AG | 1 |
| Amin, M | 1 |
| Tang, S | 1 |
| Shalamanova, L | 1 |
| Taylor, RL | 1 |
| Wylie, S | 1 |
| Abdullah, BM | 1 |
| Whitehead, KA | 1 |
| Luo, J | 1 |
| Yu, CH | 1 |
| Yu, H | 1 |
| Borstnar, R | 1 |
| Kamerlin, SC | 1 |
| Gräslund, A | 1 |
| Abrahams, JP | 1 |
| Wärmländer, SK | 1 |
| Zhou, ZQ | 1 |
| Fan, HX | 1 |
| He, RR | 1 |
| Xiao, J | 1 |
| Tsoi, B | 1 |
| Lan, KH | 1 |
| Kurihara, H | 1 |
| So, KF | 1 |
| Yao, XS | 1 |
| Gao, H | 1 |
| Palmer, AM | 1 |
| Burns, MA | 1 |
| Morrison, LD | 1 |
| Kish, SJ | 1 |
| Seidl, R | 1 |
| Beninati, S | 1 |
| Cairns, N | 1 |
| Singewald, N | 1 |
| Risser, D | 1 |
| Bavan, H | 1 |
| Nemethova, M | 1 |
| Lubec, G | 1 |
| Zhang, YH | 1 |
| Zhao, XY | 1 |
| Chen, XQ | 1 |
| Wang, Y | 1 |
| Yang, HH | 1 |
| Hu, GY | 1 |
2 reviews available for spermidine and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
Nutraceutical Approaches of Autophagy and Neuroinflammation in Alzheimer's Disease: A Systematic Review.
Topics: Alzheimer Disease; Animals; Autophagy; Catechin; Cellular Senescence; Dietary Supplements; Flavonols | 2020 |
Polyamine biomarkers as indicators of human disease.
Topics: Acrolein; Alzheimer Disease; Apoptosis; Biomarkers; Biotransformation; Cadaverine; Cell Movement; Hu | 2021 |
1 trial available for spermidine and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
The positive effect of spermidine in older adults suffering from dementia : First results of a 3-month trial.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Dementia; Humans; Memory; Mental Status and Demen | 2021 |
11 other studies available for spermidine and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
Elevated spermidine serum levels in mild cognitive impairment, a potential biomarker of progression to Alzheimer dementia, a pilot study.
Topics: Alzheimer Disease; Biomarkers; Cognitive Dysfunction; Cross-Sectional Studies; Disease Progression; | 2022 |
Spermidine reduces neuroinflammation and soluble amyloid beta in an Alzheimer's disease mouse model.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Disease Models, Animal; Mice; Neuroinflammatory D | 2022 |
Association of spermidine plasma levels with brain aging in a population-based study.
Topics: Adult; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Brain; Humans; Magnetic Resonance Imaging; | 2023 |
Spermidine Rescues Bioenergetic and Mitophagy Deficits Induced by Disease-Associated Tau Protein.
Topics: Adenosine Triphosphate; Alzheimer Disease; Energy Metabolism; Humans; Mitophagy; Neuroblastoma; Sper | 2023 |
Spermidine in dementia : Relation to age and memory performance.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Dementia; Humans; Memory; Mental Status and Dementia Tes | 2020 |
Cellular polyamines promote amyloid-beta (Aβ) peptide fibrillation and modulate the aggregation pathways.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Humans; Peptide Fragments; Polyamines; Putrescine | 2013 |
Lycibarbarspermidines A-O, New Dicaffeoylspermidine Derivatives from Wolfberry, with Activities against Alzheimer's Disease and Oxidation.
Topics: Alzheimer Disease; Antioxidants; Fruit; Glycosides; Lycium; Neuroprotective Agents; Oxidation-Reduct | 2016 |
Preservation of redox, polyamine, and glycine modulatory domains of the N-methyl-D-aspartate receptor in Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Biguanides; Binding Sites; Brain; | 1994 |
Brain polyamine levels are altered in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Biogenic Polyamines; Brain Chemistry; Calcium; Female; Humans; Male; Neurof | 1995 |
Polyamines in frontal cortex of patients with Down syndrome and Alzheimer disease.
Topics: Aged; Alzheimer Disease; Case-Control Studies; Choline O-Acetyltransferase; Down Syndrome; Female; F | 1996 |
Spermidine antagonizes the inhibitory effect of huperzine A on [3H]dizocilpine (MK-801) binding in synaptic membrane of rat cerebral cortex.
Topics: Alkaloids; Alzheimer Disease; Animals; Binding Sites; Binding, Competitive; Cerebral Cortex; Choline | 2002 |