sparsomycin and Leukemia-L5178

sparsomycin has been researched along with Leukemia-L5178* in 1 studies

Other Studies

1 other study(ies) available for sparsomycin and Leukemia-L5178

Article	Year
Sparsomycin analogs. VI. Synthesis and antitumor activity of octylsparsomycin analogs. Chemical & pharmaceutical bulletin, 1989, Volume: 37, Issue:3 Five sparsomycin analogs (9-13) were prepared and examined for their ability to inhibit deoxyribonucleic acid (DNA) synthesis in L5178Y lymphoma cells. All of the compounds showed significant activity in the DNA synthesis assay. The compounds having Rc configuration exhibited almost the same activities independently of the configuration at the sulfoxide sulfur atom. Among the Sc isomers, the Rs configuration was advantageous for the appearance of activity. Topics: Animals; Antibiotics, Antineoplastic; Chemical Phenomena; Chemistry; Leukemia L5178; Mice; Sparsomycin; Tumor Cells, Cultured	1989

Article

Year

Sparsomycin analogs. VI. Synthesis and antitumor activity of octylsparsomycin analogs.

Chemical & pharmaceutical bulletin, 1989, Volume: 37, Issue:3

Five sparsomycin analogs (9-13) were prepared and examined for their ability to inhibit deoxyribonucleic acid (DNA) synthesis in L5178Y lymphoma cells. All of the compounds showed significant activity in the DNA synthesis assay. The compounds having Rc configuration exhibited almost the same activities independently of the configuration at the sulfoxide sulfur atom. Among the Sc isomers, the Rs configuration was advantageous for the appearance of activity.

Topics: Animals; Antibiotics, Antineoplastic; Chemical Phenomena; Chemistry; Leukemia L5178; Mice; Sparsomycin; Tumor Cells, Cultured

1989