sparsomycin has been researched along with Cell-Transformation--Neoplastic* in 2 studies
2 other study(ies) available for sparsomycin and Cell-Transformation--Neoplastic
Article | Year |
---|---|
Synthesis and activity of pyrimidinylpropenamide antibiotics: the alkyl analogues of sparsomycin.
Facile syntheses of sparsomycin (3) and its four analogues (4-7) based on diastereoselective oxidation of sulfide, sulfenylation, and coupling of 6-methyluracylacryllic acid with monooxodithioacetal amine, are described. Studies on the biological activity of morphological reversion on src(ts)-NRK cells were also carried out. Topics: Animals; Antibiotics, Antineoplastic; Avian Sarcoma Viruses; Cell Transformation, Neoplastic; Mice; Oxidation-Reduction; Sparsomycin; Tumor Cells, Cultured | 2003 |
Synthesis and morphological reversion activity on srctsNRK cells of pyrimidinylpropanamide antibiotics, sparsomycin, sparoxomycin A1, A2, and their analogues.
Three pyrimidinylpropanamide antibiotics sparsomycin (1), sparoxomycins A1, A2 (2, 3), and also six analogues (4-9) have been synthesized by employing asymmetric sulfide oxidation conditions as a key step. Sparsomycin (1) and its alkyl analogues (5-7) showed higher morphological reversion activities on srctsNRK cells than 2 and 3. Topics: Antibiotics, Antineoplastic; Avian Sarcoma Viruses; Cell Line; Cell Transformation, Neoplastic; Pyrimidinones; Sparsomycin | 1998 |