sparsomycin and Cell-Transformation--Neoplastic

sparsomycin has been researched along with Cell-Transformation--Neoplastic* in 2 studies

Other Studies

2 other study(ies) available for sparsomycin and Cell-Transformation--Neoplastic

Article	Year
Synthesis and activity of pyrimidinylpropenamide antibiotics: the alkyl analogues of sparsomycin. Bioscience, biotechnology, and biochemistry, 2003, Volume: 67, Issue:12 Facile syntheses of sparsomycin (3) and its four analogues (4-7) based on diastereoselective oxidation of sulfide, sulfenylation, and coupling of 6-methyluracylacryllic acid with monooxodithioacetal amine, are described. Studies on the biological activity of morphological reversion on src(ts)-NRK cells were also carried out. Topics: Animals; Antibiotics, Antineoplastic; Avian Sarcoma Viruses; Cell Transformation, Neoplastic; Mice; Oxidation-Reduction; Sparsomycin; Tumor Cells, Cultured	2003
Synthesis and morphological reversion activity on srctsNRK cells of pyrimidinylpropanamide antibiotics, sparsomycin, sparoxomycin A1, A2, and their analogues. Bioorganic & medicinal chemistry letters, 1998, Dec-01, Volume: 8, Issue:23 Three pyrimidinylpropanamide antibiotics sparsomycin (1), sparoxomycins A1, A2 (2, 3), and also six analogues (4-9) have been synthesized by employing asymmetric sulfide oxidation conditions as a key step. Sparsomycin (1) and its alkyl analogues (5-7) showed higher morphological reversion activities on srctsNRK cells than 2 and 3. Topics: Antibiotics, Antineoplastic; Avian Sarcoma Viruses; Cell Line; Cell Transformation, Neoplastic; Pyrimidinones; Sparsomycin	1998

Article

Year

Synthesis and activity of pyrimidinylpropenamide antibiotics: the alkyl analogues of sparsomycin.

Bioscience, biotechnology, and biochemistry, 2003, Volume: 67, Issue:12

Facile syntheses of sparsomycin (3) and its four analogues (4-7) based on diastereoselective oxidation of sulfide, sulfenylation, and coupling of 6-methyluracylacryllic acid with monooxodithioacetal amine, are described. Studies on the biological activity of morphological reversion on src(ts)-NRK cells were also carried out.

Topics: Animals; Antibiotics, Antineoplastic; Avian Sarcoma Viruses; Cell Transformation, Neoplastic; Mice; Oxidation-Reduction; Sparsomycin; Tumor Cells, Cultured

2003

Synthesis and morphological reversion activity on srctsNRK cells of pyrimidinylpropanamide antibiotics, sparsomycin, sparoxomycin A1, A2, and their analogues.

Bioorganic & medicinal chemistry letters, 1998, Dec-01, Volume: 8, Issue:23

Three pyrimidinylpropanamide antibiotics sparsomycin (1), sparoxomycins A1, A2 (2, 3), and also six analogues (4-9) have been synthesized by employing asymmetric sulfide oxidation conditions as a key step. Sparsomycin (1) and its alkyl analogues (5-7) showed higher morphological reversion activities on srctsNRK cells than 2 and 3.

Topics: Antibiotics, Antineoplastic; Avian Sarcoma Viruses; Cell Line; Cell Transformation, Neoplastic; Pyrimidinones; Sparsomycin

1998